Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value ($000): $1,502,748 (100.0% shares, 0.0% debt)

Holdings (39)

WGS GENEDX HOLDINGS CORP 17.9%

Value ($000) $269,561 Shares 3,507,164 Est. Cost $9.11 Unrealized +666.5%

BLFS BIOLIFE SOLUTIONS INC 15.0%

Value ($000) $226,038 Shares 8,707,165 Est. Cost $19.43 Unrealized +28.1%

RVMD REVOLUTION MEDICINES INC 10.8%

Value ($000) $161,807 Shares 3,699,283 Est. Cost $25.89 Unrealized +94.9%

SRPT SAREPTA THERAPEUTICS INC 8.7%

Value ($000) $130,527 Shares 1,073,500 Est. Cost $100.84 Unrealized +21.5%

LAB STANDARD BIOTOOLS INC 8.3%

Value ($000) $124,696 Shares 71,254,677 Est. Cost $2.36 Unrealized -21.1%

ILMN ILLUMINA INC 6.7%

Value ($000) $100,223 Shares 750,000 Est. Cost $119.44 Unrealized +19.2%

RNAM AVIDITY BIOSCIENCES INC 4.0%

Value ($000) $59,469 Shares 2,045,000 Est. Cost $14.11 Unrealized +196.3%

CDXS CODEXIS INC 2.6%

Value ($000) $38,637 Shares 8,100,000 Est. Cost $2.87 Unrealized +43.7%

RLAY RELAY THERAPEUTICS INC 2.5%

Value ($000) $36,868 Shares 8,948,574 Est. Cost $19.94 Unrealized -72.7%

EXAS EXACT SCIENCES CORP 2.4%

Value ($000) $36,524 Shares 650,000 Est. Cost $74.77 Unrealized -16.8%

ALNY ALNYLAM PHARMACEUTICALS INC 2.2%

Value ($000) $32,943 Shares 140,000 Est. Cost $138.08 Unrealized +90.5%

BEAM BEAM THERAPEUTICS INC 2.1%

Value ($000) $31,000 Shares 1,250,000 Est. Cost $40.28 Unrealized -36.6%

NGNE NEUROGENE INC 2.0%

Value ($000) $29,612 Shares 1,295,361 Est. Cost $27.94 Unrealized +33.2%

— BLUEPRINT MEDICINES CORP 1.9%

Value ($000) $28,467 Shares 326,378 Est. Cost $3820.05 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 1.6%

Value ($000) $23,320 Shares 2,000,000 Est. Cost $37.51 Unrealized -58.4%

— VERVE THERAPEUTICS INC 1.5%

Value ($000) $22,535 Shares 3,995,571 Est. Cost $36.00 Unrealized —

DNLI DENALI THERAPEUTICS INC 1.3%

Value ($000) $20,176 Shares 990,000 Est. Cost $29.48 Unrealized -13.2%

GPCR STRUCTURE THERAPEUTICS INC 1.3%

Value ($000) $18,984 Shares 700,000 Est. Cost $33.80 Unrealized —

SEPN SEPTERNA INC 0.8%

Value ($000) $12,670 Shares 553,268 Est. Cost $23.65 Unrealized 0.0%

VCYT VERACYTE INC 0.7%

Value ($000) $10,942 Shares 276,308 Est. Cost $24.40 Unrealized +55.2%

GH GUARDANT HEALTH INC 0.7%

Value ($000) $10,693 Shares 350,000 Est. Cost $26.87 Unrealized +4.7%

TNYA TENAYA THERAPEUTICS INC 0.6%

Value ($000) $9,628 Shares 6,732,971 Est. Cost $12.86 Unrealized -82.6%

AGIO AGIOS PHARMACEUTICALS INC 0.5%

Value ($000) $8,215 Shares 250,000 Est. Cost $46.98 Unrealized 0.0%

MRNA MODERNA INC 0.5%

Value ($000) $7,277 Shares 175,000 Est. Cost $47.80 Unrealized 0.0%

MRNA MODERNA INC 0.5%

Value ($000) $7,277 Shares 175,000 Est. Cost $47.80 Unrealized 0.0%

FDMT 4D MOLECULAR THERAPEUTICS IN 0.4%

Value ($000) $6,406 Shares 1,150,000 Est. Cost $16.94 Unrealized -53.7%

SNDX SYNDAX PHARMACEUTICALS INC 0.4%

Value ($000) $6,280 Shares 475,000 Est. Cost $18.99 Unrealized -9.9%

— 2SEVENTY BIO INC 0.4%

Value ($000) $5,880 Shares 2,000,000 Est. Cost $9.15 Unrealized —

IPSC CENTURY THERAPEUTICS INC 0.3%

Value ($000) $5,242 Shares 5,190,506 Est. Cost $10.97 Unrealized -87.6%

FTRE FORTREA HLDGS INC 0.3%

Value ($000) $5,129 Shares 275,000 Est. Cost $19.49 Unrealized 0.0%

CTNM CONTINEUM THERAPEUTICS INC 0.3%

Value ($000) $4,346 Shares 296,666 Est. Cost $16.10 Unrealized -1.7%

TNGX TANGO THERAPEUTICS INC 0.2%

Value ($000) $3,672 Shares 1,188,349 Est. Cost $5.87 Unrealized -20.9%

ABSI ABSCI CORPORATION 0.2%

Value ($000) $2,550 Shares 973,260 Est. Cost $19.41 Unrealized -81.9%

PACB PACIFIC BIOSCIENCES CALIF IN 0.1%

Value ($000) $1,896 Shares 1,035,859 Est. Cost $11.43 Unrealized -82.9%

RXRX RECURSION PHARMACEUTICALS IN 0.1%

Value ($000) $1,118 Shares 165,323 Est. Cost $6.72 Unrealized 0.0%

PRME PRIME MEDICINE INC 0.1%

Value ($000) $1,072 Shares 367,175 Est. Cost $18.06 Unrealized -80.6%

GLUE MONTE ROSA THERAPEUTICS INC 0.0%

Value ($000) $597 Shares 86,014 Est. Cost $20.37 Unrealized -63.2%

DNA GINKGO BIOWORKS HOLDINGS INC 0.0%

Value ($000) $358 Shares 36,493 Est. Cost $10.02 Unrealized -14.5%

— KRONOS BIO INC 0.0%

Value ($000) $118 Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WGS	GENEDX HOLDINGS CORP	3,507,164	$269,561	17.9%	$9.11	+666.5%	COM CL A	81663L200
BLFS	BIOLIFE SOLUTIONS INC	8,707,165	$226,038	15.0%	$19.43	+28.1%	COM NEW	09062W204
RVMD	REVOLUTION MEDICINES INC	3,699,283	$161,807	10.8%	$25.89	+94.9%	COM	76155X100
SRPT	SAREPTA THERAPEUTICS INC	1,073,500	$130,527	8.7%	$100.84	+21.5%	COM	803607100
LAB	STANDARD BIOTOOLS INC	71,254,677	$124,696	8.3%	$2.36	-21.1%	COM	34385P108
ILMN	ILLUMINA INC	750,000	$100,223	6.7%	$119.44	+19.2%	COM	452327109
RNAM	AVIDITY BIOSCIENCES INC	2,045,000	$59,469	4.0%	$14.11	+196.3%	COM	05370A108
CDXS	CODEXIS INC	8,100,000	$38,637	2.6%	$2.87	+43.7%	COM	192005106
RLAY	RELAY THERAPEUTICS INC	8,948,574	$36,868	2.5%	$19.94	-72.7%	COM	75943R102
EXAS	EXACT SCIENCES CORP	650,000	$36,524	2.4%	$74.77	-16.8%	COM	30063P105
ALNY	ALNYLAM PHARMACEUTICALS INC	140,000	$32,943	2.2%	$138.08	+90.5%	COM	02043Q107
BEAM	BEAM THERAPEUTICS INC	1,250,000	$31,000	2.1%	$40.28	-36.6%	COM	07373V105
NGNE	NEUROGENE INC	1,295,361	$29,612	2.0%	$27.94	+33.2%	COM	64135M105
—	BLUEPRINT MEDICINES CORP	326,378	$28,467	1.9%	$3820.05	—	COM	09627Y109
NTLA	INTELLIA THERAPEUTICS INC	2,000,000	$23,320	1.6%	$37.51	-58.4%	COM	45826J105
—	VERVE THERAPEUTICS INC	3,995,571	$22,535	1.5%	$36.00	—	COM	92539P101
DNLI	DENALI THERAPEUTICS INC	990,000	$20,176	1.3%	$29.48	-13.2%	COM	24823R105
GPCR	STRUCTURE THERAPEUTICS INC	700,000	$18,984	1.3%	$33.80	—	SPONSORED ADS	86366E106
SEPN	SEPTERNA INC	553,268	$12,670	0.8%	$23.65	0.0%	COM	81734D104
VCYT	VERACYTE INC	276,308	$10,942	0.7%	$24.40	+55.2%	COM	92337F107
GH	GUARDANT HEALTH INC	350,000	$10,693	0.7%	$26.87	+4.7%	COM	40131M109
TNYA	TENAYA THERAPEUTICS INC	6,732,971	$9,628	0.6%	$12.86	-82.6%	COM	87990A106
AGIO	AGIOS PHARMACEUTICALS INC	250,000	$8,215	0.5%	$46.98	0.0%	COM	00847X104
MRNA	MODERNA INC	175,000	$7,277	0.5%	$47.80	0.0%	COM	60770K107
MRNA	MODERNA INC	175,000	$7,277	0.5%	$47.80	0.0%	Call	60770K107
FDMT	4D MOLECULAR THERAPEUTICS IN	1,150,000	$6,406	0.4%	$16.94	-53.7%	COM	35104E100
SNDX	SYNDAX PHARMACEUTICALS INC	475,000	$6,280	0.4%	$18.99	-9.9%	COM	87164F105
—	2SEVENTY BIO INC	2,000,000	$5,880	0.4%	$9.15	—	COMMON STOCK	901384107
IPSC	CENTURY THERAPEUTICS INC	5,190,506	$5,242	0.3%	$10.97	-87.6%	COM	15673T100
FTRE	FORTREA HLDGS INC	275,000	$5,129	0.3%	$19.49	0.0%	COMMON STOCK	34965K107
CTNM	CONTINEUM THERAPEUTICS INC	296,666	$4,346	0.3%	$16.10	-1.7%	CL A	21217B100
TNGX	TANGO THERAPEUTICS INC	1,188,349	$3,672	0.2%	$5.87	-20.9%	COM	87583X109
ABSI	ABSCI CORPORATION	973,260	$2,550	0.2%	$19.41	-81.9%	COM	00091E109
PACB	PACIFIC BIOSCIENCES CALIF IN	1,035,859	$1,896	0.1%	$11.43	-82.9%	COM	69404D108
RXRX	RECURSION PHARMACEUTICALS IN	165,323	$1,118	0.1%	$6.72	0.0%	CL A	75629V104
PRME	PRIME MEDICINE INC	367,175	$1,072	0.1%	$18.06	-80.6%	COM	74168J101
GLUE	MONTE ROSA THERAPEUTICS INC	86,014	$597	0.0%	$20.37	-63.2%	COM	61225M102
DNA	GINKGO BIOWORKS HOLDINGS INC	36,493	$358	0.0%	$10.02	-14.5%	CL A NEW	37611X209
—	KRONOS BIO INC	123,839	$118	0.0%	$29.87	—	COM	50107A104