GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q1 2015 (← Previous) (Next →)

Filing Date: May 15, 2015

Total Value: $227M (100.0% shares, 0.0% debt)

Holdings (33)

— CONNECTURE INC 25.1%

Value $56.96M Shares 5,502,965 Est. Cost $9.01 Unrealized —

— HYPERION THERAPEUTICS INC 10.1%

Value $22.95M Shares 500,000 Est. Cost $25.57 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 5.7%

Value $12.91M Shares 1,388,599 Est. Cost $11.30 Unrealized 0.0%

OM2 ORTHOFIX INTL N V 4.7%

Value $10.77M Shares 300,000 Est. Cost $34.16 Unrealized —

— ADAMAS PHARMACEUTICALS INC 4.7%

Value $10.64M Shares 608,650 Est. Cost $17.46 Unrealized —

— OCERA THERAPEUTICS INC 4.1%

Value $9.249M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— ALIMERA SCIENCES INC 3.8%

Value $8.675M Shares 1,731,550 Est. Cost $6.86 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 3.7%

Value $8.511M Shares 1,941,144 Est. Cost $3.55 Unrealized +11.7%

— DERMA SCIENCES INC 3.6%

Value $8.283M Shares 977,923 Est. Cost $12.35 Unrealized —

VCEL VERICEL CORP 3.4%

Value $7.718M Shares 2,086,028 Est. Cost $2.85 Unrealized +19.7%

— VERSARTIS INC 3.1%

Value $7.072M Shares 385,000 Est. Cost $18.37 Unrealized —

— SUCAMPO PHARMACEUTICALS INC 3.1%

Value $7.002M Shares 450,000 Est. Cost $15.56 Unrealized —

— STEMLINE THERAPEUTICS INC 3.0%

Value $6.877M Shares 475,200 Est. Cost $14.47 Unrealized —

— ARADIGM CORP 2.8%

Value $6.338M Shares 1,002,962 Est. Cost $8.85 Unrealized —

ASND ASCENDIS PHARMA A S 2.6%

Value $5.896M Shares 339,863 Est. Cost $17.35 Unrealized —

— ALCOBRA LTD 2.4%

Value $5.539M Shares 983,786 Est. Cost $5.63 Unrealized —

— DYAX CORP 1.7%

Value $3.953M Shares 235,950 Est. Cost $16.75 Unrealized —

HRTX HERON THERAPEUTICS INC 1.7%

Value $3.929M Shares 270,000 Est. Cost $11.27 Unrealized 0.0%

— TENAX THERAPEUTICS INC 1.6%

Value $3.614M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— AMPIO PHARMACEUTICALS INC 1.4%

Value $3.174M Shares 421,500 Est. Cost — Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 1.3%

Value $3.062M Shares 100,000 Est. Cost $38.91 Unrealized 0.0%

EBS EMERGENT BIOSOLUTIONS INC 1.3%

Value $2.956M Shares 102,791 Est. Cost $22.90 Unrealized +25.3%

— SUNESIS PHARMACEUTICALS INC 1.1%

Value $2.545M Shares 1,038,652 Est. Cost $2.45 Unrealized —

— ATHERSYS INC 1.1%

Value $2.391M Shares 830,200 Est. Cost — Unrealized —

— MELA SCIENCES INC 0.6%

Value $1.464M Shares 569,591 Est. Cost $2.57 Unrealized —

— BELLICUM PHARMACEUTICALS INC 0.5%

Value $1.159M Shares 50,000 Est. Cost $23.04 Unrealized —

— BOVIE MEDICAL CORP 0.5%

Value $1.147M Shares 480,000 Est. Cost $2.39 Unrealized —

— VICAL INC 0.4%

Value $800K Shares 846,762 Est. Cost $1.19 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.2%

Value $538K Shares 151,611 Est. Cost $6.45 Unrealized —

VCYT VERACYTE INC 0.2%

Value $497K Shares 68,158 Est. Cost $13.38 Unrealized -38.8%

— ATHERSYS INC 0.1%

Value $288K Shares 100,000 Est. Cost — Unrealized —

— OSIRIS THERAPEUTICS INC NEW 0.1%

Value $214K Shares 12,165 Est. Cost $17.59 Unrealized —

— MEI PHARMA INC 0.0%

Value $94,000 Shares 52,254 Est. Cost $11.25 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CONNECTURE INC	5,502,965	$56.96M	25.1%	$9.01	—	COM	20786J106
—	HYPERION THERAPEUTICS INC	500,000	$22.95M	10.1%	$25.57	—	COM	44915N101
VNDA	VANDA PHARMACEUTICALS INC	1,388,599	$12.91M	5.7%	$11.30	0.0%	COM	921659108
OM2	ORTHOFIX INTL N V	300,000	$10.77M	4.7%	$34.16	—	COM	N6748L102
—	ADAMAS PHARMACEUTICALS INC	608,650	$10.64M	4.7%	$17.46	—	COM	00548A106
—	OCERA THERAPEUTICS INC	1,963,777	$9.249M	4.1%	$6.20	—	COM	67552A108
—	ALIMERA SCIENCES INC	1,731,550	$8.675M	3.8%	$6.86	—	COM	016259103
AUPH	AURINIA PHARMACEUTICALS INC	1,941,144	$8.511M	3.7%	$3.55	+11.7%	COM	05156V102
—	DERMA SCIENCES INC	977,923	$8.283M	3.6%	$12.35	—	COM PAR $.01	249827502
VCEL	VERICEL CORP	2,086,028	$7.718M	3.4%	$2.85	+19.7%	COM	92346J108
—	VERSARTIS INC	385,000	$7.072M	3.1%	$18.37	—	COM	92529L102
—	SUCAMPO PHARMACEUTICALS INC	450,000	$7.002M	3.1%	$15.56	—	CL A	864909106
—	STEMLINE THERAPEUTICS INC	475,200	$6.877M	3.0%	$14.47	—	COM	85858C107
—	ARADIGM CORP	1,002,962	$6.338M	2.8%	$8.85	—	SPONSORED ADR	038505400
ASND	ASCENDIS PHARMA A S	339,863	$5.896M	2.6%	$17.35	—	COM	04351P101
—	ALCOBRA LTD	983,786	$5.539M	2.4%	$5.63	—	SHS	M2239P109
—	DYAX CORP	235,950	$3.953M	1.7%	$16.75	—	COM	26746E103
HRTX	HERON THERAPEUTICS INC	270,000	$3.929M	1.7%	$11.27	0.0%	COM	427746102
—	TENAX THERAPEUTICS INC	1,108,593	$3.614M	1.6%	$3.93	—	COM	88032L100
—	AMPIO PHARMACEUTICALS INC	421,500	$3.174M	1.4%	—	—	Put	03209T109
ENTA	ENANTA PHARMACEUTICALS INC	100,000	$3.062M	1.3%	$38.91	0.0%	COM	29251M106
EBS	EMERGENT BIOSOLUTIONS INC	102,791	$2.956M	1.3%	$22.90	+25.3%	COM	29089Q105
—	SUNESIS PHARMACEUTICALS INC	1,038,652	$2.545M	1.1%	$2.45	—	COM NEW	867328601
—	ATHERSYS INC	830,200	$2.391M	1.1%	—	—	Call	04744L106
—	MELA SCIENCES INC	569,591	$1.464M	0.6%	$2.57	—	COM NEW	55277R308
—	BELLICUM PHARMACEUTICALS INC	50,000	$1.159M	0.5%	$23.04	—	COM	079481107
—	BOVIE MEDICAL CORP	480,000	$1.147M	0.5%	$2.39	—	COM	10211F100
—	VICAL INC	846,762	$800K	0.4%	$1.19	—	COM	925602104
—	STREAMLINE HEALTH SOLUTIONS	151,611	$538K	0.2%	$6.45	—	COM	86323X106
VCYT	VERACYTE INC	68,158	$497K	0.2%	$13.38	-38.8%	COM	92337F107
—	ATHERSYS INC	100,000	$288K	0.1%	—	—	Put	04744L106
—	OSIRIS THERAPEUTICS INC NEW	12,165	$214K	0.1%	$17.59	—	COM	68827R108
—	MEI PHARMA INC	52,254	$94,000	0.0%	$11.25	—	COM NEW	55279B202