GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2015 (← Previous) (Next →)

Filing Date: Aug 14, 2015

Total Value: $257M (100.0% shares, 0.0% debt)

Holdings (34)

— CONNECTURE INC 17.0%

Value $43.58M Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ADAMAS PHARMACEUTICALS INC 7.9%

Value $20.26M Shares 772,600 Est. Cost $19.32 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 7.0%

Value $17.94M Shares 1,413,599 Est. Cost $11.29 Unrealized -4.5%

— FIVE PRIME THERAPEUTICS INC 6.6%

Value $16.86M Shares 678,595 Est. Cost $24.84 Unrealized —

— SYNERGY PHARMACEUTICALS DEL 6.5%

Value $16.68M Shares 2,009,984 Est. Cost $8.30 Unrealized —

— DYAX CORP 4.9%

Value $12.53M Shares 472,739 Est. Cost $21.64 Unrealized —

— PARATEK PHARMACEUTICALS INC 4.2%

Value $10.7M Shares 415,338 Est. Cost $25.77 Unrealized —

— RELYPSA INC 3.1%

Value $7.942M Shares 240,000 Est. Cost $33.09 Unrealized —

— ALCOBRA LTD 3.0%

Value $7.777M Shares 1,189,086 Est. Cost $5.79 Unrealized —

— ALIMERA SCIENCES INC 3.0%

Value $7.759M Shares 1,683,162 Est. Cost $6.86 Unrealized —

— SUNESIS PHARMACEUTICALS INC 3.0%

Value $7.65M Shares 2,541,459 Est. Cost $2.78 Unrealized —

— BOVIE MEDICAL CORP 2.9%

Value $7.477M Shares 2,680,000 Est. Cost $2.72 Unrealized —

— OCERA THERAPEUTICS INC 2.9%

Value $7.463M Shares 1,963,777 Est. Cost $6.20 Unrealized —

VCEL VERICEL CORP 2.9%

Value $7.447M Shares 2,086,028 Est. Cost $2.85 Unrealized +20.3%

— ARADIGM CORP 2.9%

Value $7.402M Shares 1,002,962 Est. Cost $8.85 Unrealized —

— ANTARES PHARMA INC 2.3%

Value $5.824M Shares 2,800,000 Est. Cost $2.08 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 2.3%

Value $5.812M Shares 1,941,144 Est. Cost $3.55 Unrealized +4.5%

— STEMLINE THERAPEUTICS INC 2.2%

Value $5.593M Shares 475,200 Est. Cost $14.47 Unrealized —

ASND ASCENDIS PHARMA A S 2.1%

Value $5.502M Shares 311,222 Est. Cost $17.35 Unrealized —

— CALADRIUS BIOSCIENCES INC 1.8%

Value $4.63M Shares 2,476,120 Est. Cost $1.87 Unrealized —

— ZOGENIX INC 1.6%

Value $4.2M Shares 2,500,000 Est. Cost $1.68 Unrealized —

— BIODEL INC 1.6%

Value $4.132M Shares 4,011,511 Est. Cost $1.03 Unrealized —

— TENAX THERAPEUTICS INC 1.6%

Value $4.091M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— SAGENT PHARMACEUTICALS INC 1.3%

Value $3.45M Shares 141,900 Est. Cost $24.31 Unrealized —

— XENOPORT INC 1.2%

Value $2.973M Shares 485,000 Est. Cost $6.13 Unrealized —

EXEL EXELIXIS INC 1.1%

Value $2.801M Shares 745,000 Est. Cost — Unrealized —

— OREXIGEN THERAPEUTICS INC 0.8%

Value $2.178M Shares 440,000 Est. Cost $4.95 Unrealized —

— DERMA SCIENCES INC 0.8%

Value $2.005M Shares 280,000 Est. Cost $12.35 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 0.6%

Value $1.575M Shares 35,000 Est. Cost $38.91 Unrealized -0.0%

— ATHERSYS INC 0.4%

Value $977K Shares 807,700 Est. Cost — Unrealized —

ESPR ESPERION THERAPEUTICS INC NE 0.3%

Value $687K Shares 8,400 Est. Cost $97.89 Unrealized 0.0%

— STREAMLINE HEALTH SOLUTIONS 0.2%

Value $424K Shares 151,611 Est. Cost $6.45 Unrealized —

— ATHERSYS INC 0.0%

Value $121K Shares 100,000 Est. Cost — Unrealized —

— BIODELIVERY SCIENCES INTL IN 0.0%

Value $82,000 Shares 10,300 Est. Cost $7.96 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CONNECTURE INC	4,127,232	$43.58M	17.0%	$9.01	—	COM	20786J106
—	ADAMAS PHARMACEUTICALS INC	772,600	$20.26M	7.9%	$19.32	—	COM	00548A106
VNDA	VANDA PHARMACEUTICALS INC	1,413,599	$17.94M	7.0%	$11.29	-4.5%	COM	921659108
—	FIVE PRIME THERAPEUTICS INC	678,595	$16.86M	6.6%	$24.84	—	COM	33830X104
—	SYNERGY PHARMACEUTICALS DEL	2,009,984	$16.68M	6.5%	$8.30	—	COM NEW	871639308
—	DYAX CORP	472,739	$12.53M	4.9%	$21.64	—	COM	26746E103
—	PARATEK PHARMACEUTICALS INC	415,338	$10.7M	4.2%	$25.77	—	COM	699374302
—	RELYPSA INC	240,000	$7.942M	3.1%	$33.09	—	COM	759531106
—	ALCOBRA LTD	1,189,086	$7.777M	3.0%	$5.79	—	SHS	M2239P109
—	ALIMERA SCIENCES INC	1,683,162	$7.759M	3.0%	$6.86	—	COM	016259103
—	SUNESIS PHARMACEUTICALS INC	2,541,459	$7.65M	3.0%	$2.78	—	COM NEW	867328601
—	BOVIE MEDICAL CORP	2,680,000	$7.477M	2.9%	$2.72	—	COM	10211F100
—	OCERA THERAPEUTICS INC	1,963,777	$7.463M	2.9%	$6.20	—	COM	67552A108
VCEL	VERICEL CORP	2,086,028	$7.447M	2.9%	$2.85	+20.3%	COM	92346J108
—	ARADIGM CORP	1,002,962	$7.402M	2.9%	$8.85	—	COM NO PAR VALUE	038505400
—	ANTARES PHARMA INC	2,800,000	$5.824M	2.3%	$2.08	—	COM	036642106
AUPH	AURINIA PHARMACEUTICALS INC	1,941,144	$5.812M	2.3%	$3.55	+4.5%	COM	05156V102
—	STEMLINE THERAPEUTICS INC	475,200	$5.593M	2.2%	$14.47	—	COM	85858C107
ASND	ASCENDIS PHARMA A S	311,222	$5.502M	2.1%	$17.35	—	SPONSORED ADR	04351P101
—	CALADRIUS BIOSCIENCES INC	2,476,120	$4.63M	1.8%	$1.87	—	COM	128058104
—	ZOGENIX INC	2,500,000	$4.2M	1.6%	$1.68	—	COM	98978L105
—	BIODEL INC	4,011,511	$4.132M	1.6%	$1.03	—	COM NEW	09064M204
—	TENAX THERAPEUTICS INC	1,108,593	$4.091M	1.6%	$3.93	—	COM	88032L100
—	SAGENT PHARMACEUTICALS INC	141,900	$3.45M	1.3%	$24.31	—	COM	786692103
—	XENOPORT INC	485,000	$2.973M	1.2%	$6.13	—	COM	98411C100
EXEL	EXELIXIS INC	745,000	$2.801M	1.1%	—	—	Put	30161Q104
—	OREXIGEN THERAPEUTICS INC	440,000	$2.178M	0.8%	$4.95	—	COM	686164104
—	DERMA SCIENCES INC	280,000	$2.005M	0.8%	$12.35	—	COM PAR $.01	249827502
ENTA	ENANTA PHARMACEUTICALS INC	35,000	$1.575M	0.6%	$38.91	-0.0%	COM	29251M106
—	ATHERSYS INC	807,700	$977K	0.4%	—	—	Call	04744L106
ESPR	ESPERION THERAPEUTICS INC NE	8,400	$687K	0.3%	$97.89	0.0%	COM	29664W105
—	STREAMLINE HEALTH SOLUTIONS	151,611	$424K	0.2%	$6.45	—	COM	86323X106
—	ATHERSYS INC	100,000	$121K	0.0%	—	—	Put	04744L106
—	BIODELIVERY SCIENCES INTL IN	10,300	$82,000	0.0%	$7.96	—	COM	09060J106