GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q2 2017 (← Previous) (Next →)

Filing Date: Aug 14, 2017

Total Value ($000): $558,190 (100.0% shares, 0.0% debt)

Holdings (38)

— ARENA PHARMACEUTICALS INC 7.4%

Value ($000) $41,162 Shares 2,439,930 Est. Cost $16.87 Unrealized —

— ADAMAS PHARMACEUTICALS INC 6.9%

Value ($000) $38,764 Shares 2,216,351 Est. Cost $18.31 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 6.5%

Value ($000) $36,385 Shares 2,232,238 Est. Cost $10.87 Unrealized +32.6%

— ZOGENIX INC 6.3%

Value ($000) $35,394 Shares 2,440,959 Est. Cost $11.56 Unrealized —

PTCT PTC THERAPEUTICS INC 6.2%

Value ($000) $34,827 Shares 1,900,000 Est. Cost $12.42 Unrealized +8.5%

— SYNERGY PHARMACEUTICALS DEL 5.8%

Value ($000) $32,145 Shares 7,223,509 Est. Cost $4.54 Unrealized —

— CONCERT PHARMACEUTICALS INC 5.0%

Value ($000) $27,900 Shares 2,000,000 Est. Cost $17.06 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 4.9%

Value ($000) $27,600 Shares 600,000 Est. Cost $43.70 Unrealized +11.0%

— RIGEL PHARMACEUTICALS INC 4.5%

Value ($000) $24,859 Shares 9,105,691 Est. Cost $3.31 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 4.0%

Value ($000) $22,187 Shares 4,781,708 Est. Cost $7.50 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 4.0%

Value ($000) $22,078 Shares 276,800 Est. Cost $62.99 Unrealized +1.5%

— SAGE THERAPEUTICS INC 3.5%

Value ($000) $19,416 Shares 243,800 Est. Cost $36.69 Unrealized —

— SELECTA BIOSCIENCES INC 3.3%

Value ($000) $18,619 Shares 937,500 Est. Cost $19.86 Unrealized —

— IGNYTA INC 3.2%

Value ($000) $18,105 Shares 1,749,323 Est. Cost $5.55 Unrealized —

— DBV TECHNOLOGIES SA 3.2%

Value ($000) $17,855 Shares 500,000 Est. Cost $35.48 Unrealized —

— ACCELERON PHARMA INC 2.7%

Value ($000) $14,997 Shares 493,500 Est. Cost $28.01 Unrealized —

PCRX PACIRA PHARMACEUTICALS INC 2.6%

Value ($000) $14,310 Shares 300,000 Est. Cost $46.40 Unrealized 0.0%

— SEATTLE GENETICS INC 2.3%

Value ($000) $12,909 Shares 249,500 Est. Cost — Unrealized —

— PORTOLA PHARMACEUTICALS INC 2.2%

Value ($000) $12,144 Shares 216,200 Est. Cost — Unrealized —

— NEURODERM LTD 1.7%

Value ($000) $9,299 Shares 311,000 Est. Cost $26.55 Unrealized —

INSM INSMED INC 1.7%

Value ($000) $9,240 Shares 538,473 Est. Cost $17.08 Unrealized 0.0%

— AIMMUNE THERAPEUTICS INC 1.6%

Value ($000) $8,952 Shares 435,402 Est. Cost $20.89 Unrealized —

— NEWLINK GENETICS CORP 1.4%

Value ($000) $8,032 Shares 1,092,849 Est. Cost $7.35 Unrealized —

— BOVIE MEDICAL CORP 1.3%

Value ($000) $7,222 Shares 2,924,015 Est. Cost $2.83 Unrealized —

— AMARIN CORPORATION PLC 1.3%

Value ($000) $7,133 Shares 1,770,000 Est. Cost $4.03 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 1.3%

Value ($000) $6,985 Shares 255,400 Est. Cost $14.45 Unrealized —

PTCT PTC THERAPEUTICS INC 0.9%

Value ($000) $4,766 Shares 260,000 Est. Cost $12.42 Unrealized +8.5%

— DYNAVAX TECHNOLOGIES CORP 0.8%

Value ($000) $4,203 Shares 435,500 Est. Cost $9.65 Unrealized —

— CARA THERAPEUTICS INC 0.7%

Value ($000) $4,177 Shares 271,400 Est. Cost $15.38 Unrealized —

— SAGE THERAPEUTICS INC 0.7%

Value ($000) $4,109 Shares 51,600 Est. Cost $36.69 Unrealized —

— SUNESIS PHARMACEUTICALS INC 0.7%

Value ($000) $3,864 Shares 1,431,149 Est. Cost $4.14 Unrealized —

— MYOVANT SCIENCES LTD 0.5%

Value ($000) $2,900 Shares 247,899 Est. Cost $12.34 Unrealized —

— CONNECTURE INC 0.5%

Value ($000) $2,550 Shares 4,127,232 Est. Cost $9.01 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.2%

Value ($000) $1,242 Shares 169,014 Est. Cost $6.36 Unrealized 0.0%

— ARADIGM CORP 0.1%

Value ($000) $835 Shares 637,279 Est. Cost $8.85 Unrealized —

— CARA THERAPEUTICS INC 0.1%

Value ($000) $761 Shares 49,471 Est. Cost $15.38 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.0%

Value ($000) $139 Shares 130,137 Est. Cost $6.45 Unrealized —

FOLD AMICUS THERAPEUTICS INC 0.0%

Value ($000) $125 Shares 12,400 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	ARENA PHARMACEUTICALS INC	2,439,930	$41,162	7.4%	$16.87	—	COM NEW	040047607
—	ADAMAS PHARMACEUTICALS INC	2,216,351	$38,764	6.9%	$18.31	—	COM	00548A106
VNDA	VANDA PHARMACEUTICALS INC	2,232,238	$36,385	6.5%	$10.87	+32.6%	COM	921659108
—	ZOGENIX INC	2,440,959	$35,394	6.3%	$11.56	—	COM NEW	98978L204
PTCT	PTC THERAPEUTICS INC	1,900,000	$34,827	6.2%	$12.42	+8.5%	COM	69366J200
—	SYNERGY PHARMACEUTICALS DEL	7,223,509	$32,145	5.8%	$4.54	—	COM NEW	871639308
—	CONCERT PHARMACEUTICALS INC	2,000,000	$27,900	5.0%	$17.06	—	COM	206022105
NBIX	NEUROCRINE BIOSCIENCES INC	600,000	$27,600	4.9%	$43.70	+11.0%	COM	64125C109
—	RIGEL PHARMACEUTICALS INC	9,105,691	$24,859	4.5%	$3.31	—	COM NEW	766559603
—	FOAMIX PHARMACEUTICALS LTD	4,781,708	$22,187	4.0%	$7.50	—	SHS	M46135105
ALNY	ALNYLAM PHARMACEUTICALS INC	276,800	$22,078	4.0%	$62.99	+1.5%	COM	02043Q107
—	SAGE THERAPEUTICS INC	243,800	$19,416	3.5%	$36.69	—	COM	78667J108
—	SELECTA BIOSCIENCES INC	937,500	$18,619	3.3%	$19.86	—	COM	816212104
—	IGNYTA INC	1,749,323	$18,105	3.2%	$5.55	—	COM	451731103
—	DBV TECHNOLOGIES SA	500,000	$17,855	3.2%	$35.48	—	SPONSORED ADR	23306J101
—	ACCELERON PHARMA INC	493,500	$14,997	2.7%	$28.01	—	COM	00434H108
PCRX	PACIRA PHARMACEUTICALS INC	300,000	$14,310	2.6%	$46.40	0.0%	COM	695127100
—	SEATTLE GENETICS INC	249,500	$12,909	2.3%	—	—	Call	812578102
—	PORTOLA PHARMACEUTICALS INC	216,200	$12,144	2.2%	—	—	Call	737010108
—	NEURODERM LTD	311,000	$9,299	1.7%	$26.55	—	ORD SHS	M74231107
INSM	INSMED INC	538,473	$9,240	1.7%	$17.08	0.0%	COM PAR	457669307
—	AIMMUNE THERAPEUTICS INC	435,402	$8,952	1.6%	$20.89	—	COM	00900T107
—	NEWLINK GENETICS CORP	1,092,849	$8,032	1.4%	$7.35	—	COM	651511107
—	BOVIE MEDICAL CORP	2,924,015	$7,222	1.3%	$2.83	—	COM	10211F100
—	AMARIN CORPORATION PLC	1,770,000	$7,133	1.3%	$4.03	—	SPONS ADR NEW	023111206
—	GLOBAL BLOOD THERAPEUTICS IN	255,400	$6,985	1.3%	$14.45	—	COM	37890U108
PTCT	PTC THERAPEUTICS INC	260,000	$4,766	0.9%	$12.42	+8.5%	Call	69366J200
—	DYNAVAX TECHNOLOGIES CORP	435,500	$4,203	0.8%	$9.65	—	COM NEW	268158201
—	CARA THERAPEUTICS INC	271,400	$4,177	0.7%	$15.38	—	Put	140755109
—	SAGE THERAPEUTICS INC	51,600	$4,109	0.7%	$36.69	—	Put	78667J108
—	SUNESIS PHARMACEUTICALS INC	1,431,149	$3,864	0.7%	$4.14	—	COM PAR	867328700
—	MYOVANT SCIENCES LTD	247,899	$2,900	0.5%	$12.34	—	COM	G637AM102
—	CONNECTURE INC	4,127,232	$2,550	0.5%	$9.01	—	COM	20786J106
IOVA	IOVANCE BIOTHERAPEUTICS INC	169,014	$1,242	0.2%	$6.36	0.0%	COM	462260100
—	ARADIGM CORP	637,279	$835	0.1%	$8.85	—	COM PAR	038505400
—	CARA THERAPEUTICS INC	49,471	$761	0.1%	$15.38	—	COM	140755109
—	STREAMLINE HEALTH SOLUTIONS	130,137	$139	0.0%	$6.45	—	COM	86323X106
FOLD	AMICUS THERAPEUTICS INC	12,400	$125	0.0%	—	—	Call	03152W109