GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2017 (← Previous) (Next →)

Filing Date: Aug 14, 2017

Total Value: $558M (100.0% shares, 0.0% debt)

Holdings (38)

— ARENA PHARMACEUTICALS INC 7.4%

Value $41.16M Shares 2,439,930 Est. Cost $16.87 Unrealized —

— ADAMAS PHARMACEUTICALS INC 6.9%

Value $38.76M Shares 2,216,351 Est. Cost $18.31 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 6.5%

Value $36.38M Shares 2,232,238 Est. Cost $10.87 Unrealized +32.6%

— ZOGENIX INC 6.3%

Value $35.39M Shares 2,440,959 Est. Cost $11.56 Unrealized —

PTCT PTC THERAPEUTICS INC 6.2%

Value $34.83M Shares 1,900,000 Est. Cost $12.42 Unrealized +8.5%

— SYNERGY PHARMACEUTICALS DEL 5.8%

Value $32.15M Shares 7,223,509 Est. Cost $4.54 Unrealized —

— CONCERT PHARMACEUTICALS INC 5.0%

Value $27.9M Shares 2,000,000 Est. Cost $17.06 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 4.9%

Value $27.6M Shares 600,000 Est. Cost $43.70 Unrealized +11.0%

— RIGEL PHARMACEUTICALS INC 4.5%

Value $24.86M Shares 9,105,691 Est. Cost $3.31 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 4.0%

Value $22.19M Shares 4,781,708 Est. Cost $7.50 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 4.0%

Value $22.08M Shares 276,800 Est. Cost $62.99 Unrealized +1.5%

— SAGE THERAPEUTICS INC 3.5%

Value $19.42M Shares 243,800 Est. Cost $36.69 Unrealized —

— SELECTA BIOSCIENCES INC 3.3%

Value $18.62M Shares 937,500 Est. Cost $19.86 Unrealized —

— IGNYTA INC 3.2%

Value $18.11M Shares 1,749,323 Est. Cost $5.55 Unrealized —

— DBV TECHNOLOGIES SA 3.2%

Value $17.86M Shares 500,000 Est. Cost $35.48 Unrealized —

— ACCELERON PHARMA INC 2.7%

Value $15M Shares 493,500 Est. Cost $28.01 Unrealized —

PCRX PACIRA PHARMACEUTICALS INC 2.6%

Value $14.31M Shares 300,000 Est. Cost $46.40 Unrealized 0.0%

— SEATTLE GENETICS INC 2.3%

Value $12.91M Shares 249,500 Est. Cost — Unrealized —

— PORTOLA PHARMACEUTICALS INC 2.2%

Value $12.14M Shares 216,200 Est. Cost — Unrealized —

— NEURODERM LTD 1.7%

Value $9.299M Shares 311,000 Est. Cost $26.55 Unrealized —

INSM INSMED INC 1.7%

Value $9.24M Shares 538,473 Est. Cost $17.08 Unrealized 0.0%

— AIMMUNE THERAPEUTICS INC 1.6%

Value $8.952M Shares 435,402 Est. Cost $20.89 Unrealized —

— NEWLINK GENETICS CORP 1.4%

Value $8.032M Shares 1,092,849 Est. Cost $7.35 Unrealized —

— BOVIE MEDICAL CORP 1.3%

Value $7.222M Shares 2,924,015 Est. Cost $2.83 Unrealized —

— AMARIN CORPORATION PLC 1.3%

Value $7.133M Shares 1,770,000 Est. Cost $4.03 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 1.3%

Value $6.985M Shares 255,400 Est. Cost $14.45 Unrealized —

PTCT PTC THERAPEUTICS INC 0.9%

Value $4.766M Shares 260,000 Est. Cost $12.42 Unrealized +8.5%

— DYNAVAX TECHNOLOGIES CORP 0.8%

Value $4.203M Shares 435,500 Est. Cost $9.65 Unrealized —

— CARA THERAPEUTICS INC 0.7%

Value $4.177M Shares 271,400 Est. Cost $15.38 Unrealized —

— SAGE THERAPEUTICS INC 0.7%

Value $4.109M Shares 51,600 Est. Cost $36.69 Unrealized —

— SUNESIS PHARMACEUTICALS INC 0.7%

Value $3.864M Shares 1,431,149 Est. Cost $4.14 Unrealized —

— MYOVANT SCIENCES LTD 0.5%

Value $2.9M Shares 247,899 Est. Cost $12.34 Unrealized —

— CONNECTURE INC 0.5%

Value $2.55M Shares 4,127,232 Est. Cost $9.01 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.2%

Value $1.242M Shares 169,014 Est. Cost $6.36 Unrealized 0.0%

— ARADIGM CORP 0.1%

Value $835K Shares 637,279 Est. Cost $8.85 Unrealized —

— CARA THERAPEUTICS INC 0.1%

Value $761K Shares 49,471 Est. Cost $15.38 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.0%

Value $139K Shares 130,137 Est. Cost $6.45 Unrealized —

FOLD AMICUS THERAPEUTICS INC 0.0%

Value $125K Shares 12,400 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ARENA PHARMACEUTICALS INC	2,439,930	$41.16M	7.4%	$16.87	—	COM NEW	040047607
—	ADAMAS PHARMACEUTICALS INC	2,216,351	$38.76M	6.9%	$18.31	—	COM	00548A106
VNDA	VANDA PHARMACEUTICALS INC	2,232,238	$36.38M	6.5%	$10.87	+32.6%	COM	921659108
—	ZOGENIX INC	2,440,959	$35.39M	6.3%	$11.56	—	COM NEW	98978L204
PTCT	PTC THERAPEUTICS INC	1,900,000	$34.83M	6.2%	$12.42	+8.5%	COM	69366J200
—	SYNERGY PHARMACEUTICALS DEL	7,223,509	$32.15M	5.8%	$4.54	—	COM NEW	871639308
—	CONCERT PHARMACEUTICALS INC	2,000,000	$27.9M	5.0%	$17.06	—	COM	206022105
NBIX	NEUROCRINE BIOSCIENCES INC	600,000	$27.6M	4.9%	$43.70	+11.0%	COM	64125C109
—	RIGEL PHARMACEUTICALS INC	9,105,691	$24.86M	4.5%	$3.31	—	COM NEW	766559603
—	FOAMIX PHARMACEUTICALS LTD	4,781,708	$22.19M	4.0%	$7.50	—	SHS	M46135105
ALNY	ALNYLAM PHARMACEUTICALS INC	276,800	$22.08M	4.0%	$62.99	+1.5%	COM	02043Q107
—	SAGE THERAPEUTICS INC	243,800	$19.42M	3.5%	$36.69	—	COM	78667J108
—	SELECTA BIOSCIENCES INC	937,500	$18.62M	3.3%	$19.86	—	COM	816212104
—	IGNYTA INC	1,749,323	$18.11M	3.2%	$5.55	—	COM	451731103
—	DBV TECHNOLOGIES SA	500,000	$17.86M	3.2%	$35.48	—	SPONSORED ADR	23306J101
—	ACCELERON PHARMA INC	493,500	$15M	2.7%	$28.01	—	COM	00434H108
PCRX	PACIRA PHARMACEUTICALS INC	300,000	$14.31M	2.6%	$46.40	0.0%	COM	695127100
—	SEATTLE GENETICS INC	249,500	$12.91M	2.3%	—	—	Call	812578102
—	PORTOLA PHARMACEUTICALS INC	216,200	$12.14M	2.2%	—	—	Call	737010108
—	NEURODERM LTD	311,000	$9.299M	1.7%	$26.55	—	ORD SHS	M74231107
INSM	INSMED INC	538,473	$9.24M	1.7%	$17.08	0.0%	COM PAR	457669307
—	AIMMUNE THERAPEUTICS INC	435,402	$8.952M	1.6%	$20.89	—	COM	00900T107
—	NEWLINK GENETICS CORP	1,092,849	$8.032M	1.4%	$7.35	—	COM	651511107
—	BOVIE MEDICAL CORP	2,924,015	$7.222M	1.3%	$2.83	—	COM	10211F100
—	AMARIN CORPORATION PLC	1,770,000	$7.133M	1.3%	$4.03	—	SPONS ADR NEW	023111206
—	GLOBAL BLOOD THERAPEUTICS IN	255,400	$6.985M	1.3%	$14.45	—	COM	37890U108
PTCT	PTC THERAPEUTICS INC	260,000	$4.766M	0.9%	$12.42	+8.5%	Call	69366J200
—	DYNAVAX TECHNOLOGIES CORP	435,500	$4.203M	0.8%	$9.65	—	COM NEW	268158201
—	CARA THERAPEUTICS INC	271,400	$4.177M	0.7%	$15.38	—	Put	140755109
—	SAGE THERAPEUTICS INC	51,600	$4.109M	0.7%	$36.69	—	Put	78667J108
—	SUNESIS PHARMACEUTICALS INC	1,431,149	$3.864M	0.7%	$4.14	—	COM PAR	867328700
—	MYOVANT SCIENCES LTD	247,899	$2.9M	0.5%	$12.34	—	COM	G637AM102
—	CONNECTURE INC	4,127,232	$2.55M	0.5%	$9.01	—	COM	20786J106
IOVA	IOVANCE BIOTHERAPEUTICS INC	169,014	$1.242M	0.2%	$6.36	0.0%	COM	462260100
—	ARADIGM CORP	637,279	$835K	0.1%	$8.85	—	COM PAR	038505400
—	CARA THERAPEUTICS INC	49,471	$761K	0.1%	$15.38	—	COM	140755109
—	STREAMLINE HEALTH SOLUTIONS	130,137	$139K	0.0%	$6.45	—	COM	86323X106
FOLD	AMICUS THERAPEUTICS INC	12,400	$125K	0.0%	—	—	Call	03152W109