GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q1 2017 (← Previous) (Next →)

Filing Date: May 15, 2017

Total Value: $504M (100.0% shares, 0.0% debt)

Holdings (37)

— ADAMAS PHARMACEUTICALS INC 9.0%

Value $45.52M Shares 2,601,351 Est. Cost $18.31 Unrealized —

— CONCERT PHARMACEUTICALS INC 7.5%

Value $37.53M Shares 2,200,000 Est. Cost $17.06 Unrealized —

— SYNERGY PHARMACEUTICALS DEL 6.7%

Value $33.66M Shares 7,223,509 Est. Cost $4.54 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 6.2%

Value $31.25M Shares 2,232,238 Est. Cost $10.87 Unrealized +31.1%

— RIGEL PHARMACEUTICALS INC 6.0%

Value $30.14M Shares 9,105,691 Est. Cost $3.31 Unrealized —

— ZOGENIX INC 5.3%

Value $26.48M Shares 2,440,959 Est. Cost $11.56 Unrealized —

— IGNYTA INC 5.2%

Value $26.41M Shares 3,071,300 Est. Cost $5.55 Unrealized —

— THERAPEUTICSMD INC 4.9%

Value $24.91M Shares 3,460,225 Est. Cost $5.85 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 4.8%

Value $24.25M Shares 560,000 Est. Cost $43.36 Unrealized -1.2%

— SAGE THERAPEUTICS INC 4.3%

Value $21.45M Shares 301,809 Est. Cost $36.69 Unrealized —

— SAGE THERAPEUTICS INC 4.2%

Value $21.32M Shares 300,000 Est. Cost $36.69 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 3.6%

Value $18.22M Shares 3,681,708 Est. Cost $8.36 Unrealized —

— DBV TECHNOLOGIES S A 3.4%

Value $17.11M Shares 485,915 Est. Cost $35.48 Unrealized —

— AVEXIS INC 3.0%

Value $15.21M Shares 200,000 Est. Cost $41.71 Unrealized —

PTCT PTC THERAPEUTICS INC 2.9%

Value $14.45M Shares 1,468,521 Est. Cost $12.10 Unrealized 0.0%

ALNY ALNYLAM PHARMACEUTICALS INC 2.5%

Value $12.81M Shares 250,000 Est. Cost $41.87 Unrealized +10.4%

— GLOBAL BLOOD THERAPEUTICS IN 2.2%

Value $11.05M Shares 300,000 Est. Cost $14.45 Unrealized —

— PARATEK PHARMACEUTICALS INC 2.1%

Value $10.39M Shares 539,571 Est. Cost $19.25 Unrealized —

— ACORDA THERAPEUTICS INC 1.8%

Value $9.083M Shares 432,500 Est. Cost — Unrealized —

— NEURODERM LTD 1.7%

Value $8.356M Shares 314,724 Est. Cost $26.55 Unrealized —

— BOVIE MEDICAL CORP 1.6%

Value $8.157M Shares 3,055,000 Est. Cost $2.83 Unrealized —

— ACCELERON PHARMA INC 1.6%

Value $7.941M Shares 300,000 Est. Cost $26.47 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 1.5%

Value $7.34M Shares 1,000,000 Est. Cost $4.62 Unrealized 0.0%

— SUNESIS PHARMACEUTICALS INC 1.3%

Value $6.305M Shares 1,537,873 Est. Cost $4.14 Unrealized —

— FIVE PRIME THERAPEUTICS INC 1.1%

Value $5.613M Shares 155,265 Est. Cost $36.15 Unrealized —

— BLUEPRINT MEDICINES CORP 1.0%

Value $4.884M Shares 122,129 Est. Cost $39.99 Unrealized —

— MYOVANT SCIENCES LTD 1.0%

Value $4.785M Shares 407,559 Est. Cost $12.34 Unrealized —

— CONNECTURE INC 0.9%

Value $4.416M Shares 4,127,232 Est. Cost $9.01 Unrealized —

JAZZ JAZZ PHARMACEUTICALS PLC 0.7%

Value $3.628M Shares 25,000 Est. Cost $130.25 Unrealized 0.0%

— AIMMUNE THERAPEUTICS INC 0.5%

Value $2.661M Shares 122,455 Est. Cost $21.73 Unrealized —

— RADIUS HEALTH INC 0.4%

Value $1.933M Shares 50,000 Est. Cost — Unrealized —

— ACORDA THERAPEUTICS INC 0.3%

Value $1.68M Shares 80,000 Est. Cost — Unrealized —

— CASCADIAN THERAPEUTICS INC 0.3%

Value $1.565M Shares 377,900 Est. Cost $4.14 Unrealized —

— TREVENA INC 0.2%

Value $1.242M Shares 338,292 Est. Cost $5.88 Unrealized —

— ARADIGM CORP 0.2%

Value $988K Shares 637,279 Est. Cost $8.85 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 0.1%

Value $590K Shares 11,517 Est. Cost $41.87 Unrealized +10.4%

— STREAMLINE HEALTH SOLUTIONS 0.0%

Value $155K Shares 151,611 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ADAMAS PHARMACEUTICALS INC	2,601,351	$45.52M	9.0%	$18.31	—	COM	00548A106
—	CONCERT PHARMACEUTICALS INC	2,200,000	$37.53M	7.5%	$17.06	—	COM	206022105
—	SYNERGY PHARMACEUTICALS DEL	7,223,509	$33.66M	6.7%	$4.54	—	COM NEW	871639308
VNDA	VANDA PHARMACEUTICALS INC	2,232,238	$31.25M	6.2%	$10.87	+31.1%	COM	921659108
—	RIGEL PHARMACEUTICALS INC	9,105,691	$30.14M	6.0%	$3.31	—	COM NEW	766559603
—	ZOGENIX INC	2,440,959	$26.48M	5.3%	$11.56	—	COM NEW	98978L204
—	IGNYTA INC	3,071,300	$26.41M	5.2%	$5.55	—	COM	451731103
—	THERAPEUTICSMD INC	3,460,225	$24.91M	4.9%	$5.85	—	COM	88338N107
NBIX	NEUROCRINE BIOSCIENCES INC	560,000	$24.25M	4.8%	$43.36	-1.2%	COM	64125C109
—	SAGE THERAPEUTICS INC	301,809	$21.45M	4.3%	$36.69	—	COM	78667J108
—	SAGE THERAPEUTICS INC	300,000	$21.32M	4.2%	$36.69	—	Put	78667J108
—	FOAMIX PHARMACEUTICALS LTD	3,681,708	$18.22M	3.6%	$8.36	—	SHS	M46135105
—	DBV TECHNOLOGIES S A	485,915	$17.11M	3.4%	$35.48	—	SPONSORED ADR	23306J101
—	AVEXIS INC	200,000	$15.21M	3.0%	$41.71	—	COM	05366U100
PTCT	PTC THERAPEUTICS INC	1,468,521	$14.45M	2.9%	$12.10	0.0%	COM	69366J200
ALNY	ALNYLAM PHARMACEUTICALS INC	250,000	$12.81M	2.5%	$41.87	+10.4%	Call	02043Q107
—	GLOBAL BLOOD THERAPEUTICS IN	300,000	$11.05M	2.2%	$14.45	—	COM	37890U108
—	PARATEK PHARMACEUTICALS INC	539,571	$10.39M	2.1%	$19.25	—	COM	699374302
—	ACORDA THERAPEUTICS INC	432,500	$9.083M	1.8%	—	—	Put	00484M106
—	NEURODERM LTD	314,724	$8.356M	1.7%	$26.55	—	ORD SHS	M74231107
—	BOVIE MEDICAL CORP	3,055,000	$8.157M	1.6%	$2.83	—	COM	10211F100
—	ACCELERON PHARMA INC	300,000	$7.941M	1.6%	$26.47	—	COM	00434H108
AUPH	AURINIA PHARMACEUTICALS INC	1,000,000	$7.34M	1.5%	$4.62	0.0%	COM	05156V102
—	SUNESIS PHARMACEUTICALS INC	1,537,873	$6.305M	1.3%	$4.14	—	COM PAR	867328700
—	FIVE PRIME THERAPEUTICS INC	155,265	$5.613M	1.1%	$36.15	—	COM	33830X104
—	BLUEPRINT MEDICINES CORP	122,129	$4.884M	1.0%	$39.99	—	COM	09627Y109
—	MYOVANT SCIENCES LTD	407,559	$4.785M	1.0%	$12.34	—	COM	G637AM102
—	CONNECTURE INC	4,127,232	$4.416M	0.9%	$9.01	—	COM	20786J106
JAZZ	JAZZ PHARMACEUTICALS PLC	25,000	$3.628M	0.7%	$130.25	0.0%	SHS USD	G50871105
—	AIMMUNE THERAPEUTICS INC	122,455	$2.661M	0.5%	$21.73	—	COM	00900T107
—	RADIUS HEALTH INC	50,000	$1.933M	0.4%	—	—	Put	750469207
—	ACORDA THERAPEUTICS INC	80,000	$1.68M	0.3%	—	—	Call	00484M106
—	CASCADIAN THERAPEUTICS INC	377,900	$1.565M	0.3%	$4.14	—	COM NEW	14740B606
—	TREVENA INC	338,292	$1.242M	0.2%	$5.88	—	COM	89532E109
—	ARADIGM CORP	637,279	$988K	0.2%	$8.85	—	COM NO PAR VALUE	038505400
ALNY	ALNYLAM PHARMACEUTICALS INC	11,517	$590K	0.1%	$41.87	+10.4%	COM	02043Q107
—	STREAMLINE HEALTH SOLUTIONS	151,611	$155K	0.0%	$6.45	—	COM	86323X106