GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2019 (← Previous) (Next →)

Filing Date: Aug 14, 2019

Total Value: $900.8B (100.0% shares, 0.0% debt)

Holdings (30)

IOVA IOVANCE BIOTHERAPEUTICS, INC. 14.3%

Value $129B Shares 5,260,803 Est. Cost $9.91 Unrealized +52.0%

PTCT PTC THERAPEUTICS, INC. 9.9%

Value $88.85B Shares 1,974,385 Est. Cost $28.46 Unrealized +38.7%

— ZOGENIX, INC. 8.5%

Value $76.13B Shares 1,593,396 Est. Cost $11839.82 Unrealized —

— AUDENTES THERAPEUTICS, INC. 8.1%

Value $72.8B Shares 1,922,937 Est. Cost $6914.70 Unrealized —

KURA KURA ONCOLOGY, INC. 6.7%

Value $60.01B Shares 3,047,800 Est. Cost $12.67 Unrealized +31.0%

— ACCELERON PHARMA INC 6.6%

Value $59.54B Shares 1,449,300 Est. Cost $18289.17 Unrealized —

ASND ASCENDIS PHARMA AS 6.4%

Value $57.58B Shares 500,000 Est. Cost $19673.19 Unrealized —

— TRICIDA, INC. 6.2%

Value $56.19B Shares 1,423,998 Est. Cost $39460.03 Unrealized —

ACAD ACADIA PHARMACEUTICALS, INC. 4.5%

Value $40.09B Shares 1,500,000 Est. Cost $18.73 Unrealized +36.4%

— MIRATI THERAPEUTICS INC. 3.4%

Value $30.9B Shares 300,000 Est. Cost $103000.00 Unrealized —

— MIRATI THERAPEUTICS INC. 3.4%

Value $30.9B Shares 300,000 Est. Cost $103000.00 Unrealized —

— ZYMEWORKS INC. 2.6%

Value $23.41B Shares 1,064,041 Est. Cost $21698.24 Unrealized —

— RETROPHIN INC. 2.2%

Value $20.16B Shares 1,003,600 Est. Cost $20089.68 Unrealized —

— MIRATII THERAPEUTICS INC. 2.0%

Value $18.02B Shares 175,000 Est. Cost $103000.00 Unrealized —

PRTA PROTHENA CORPORATION PLC 2.0%

Value $17.72B Shares 1,676,250 Est. Cost $10.27 Unrealized 0.0%

— BIOHAVEN PHARMACEUTICAL HOLDING CO LTD. 1.7%

Value $15.33B Shares 350,000 Est. Cost $43791.43 Unrealized —

— MILLENDO THERAPEUTICS, INC. 1.7%

Value $14.89B Shares 1,288,093 Est. Cost $7.95 Unrealized —

— DERMIRA INC. 1.6%

Value $14.85B Shares 1,552,900 Est. Cost $338.76 Unrealized —

— ZOGENIX, INC. 1.6%

Value $14.33B Shares 300,000 Est. Cost $11839.82 Unrealized —

GNFTY GENFIT 1.5%

Value $13.71B Shares 694,253 Est. Cost $24.00 Unrealized —

— MENLO THERAPEUTICS INC. 1.2%

Value $10.39B Shares 1,733,882 Est. Cost $7.51 Unrealized —

— BIOHAVEN PHARMACEUTICAL HOLDING CO. LTD. 1.0%

Value $8.758B Shares 200,000 Est. Cost $43791.43 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 0.6%

Value $5.022B Shares 2,110,071 Est. Cost $7.50 Unrealized —

IOVA IOVANCE BIOTHERAPETUICS, INC. 0.5%

Value $4.904B Shares 200,000 Est. Cost $9.91 Unrealized +52.0%

— MOMENTA PHARMACEUTICALS, INC. 0.5%

Value $4.259B Shares 342,064 Est. Cost $1196.13 Unrealized —

RVLPQ OSMOTICA PHARMACEUTICALS PLC 0.4%

Value $3.522B Shares 926,933 Est. Cost $8.00 Unrealized -58.5%

— PROTEOSTASIS THERAPEUTICS INC. 0.4%

Value $3.416B Shares 3,500,000 Est. Cost $2.98 Unrealized —

— FIVE PRIME THERAPEUTICS, INC. 0.4%

Value $3.303B Shares 547,712 Est. Cost $6226.03 Unrealized —

— ZAFGEN INC. 0.3%

Value $2.631B Shares 2,211,194 Est. Cost $9.93 Unrealized —

— STREAMLINE HEALTH SOLUTNS, INC. 0.0%

Value $197M Shares 130,137 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
IOVA	IOVANCE BIOTHERAPEUTICS, INC.	5,260,803	$129B	14.3%	$9.91	+52.0%	COM	462260100
PTCT	PTC THERAPEUTICS, INC.	1,974,385	$88.85B	9.9%	$28.46	+38.7%	COM	69366J200
—	ZOGENIX, INC.	1,593,396	$76.13B	8.5%	$11839.82	—	COM	98978L204
—	AUDENTES THERAPEUTICS, INC.	1,922,937	$72.8B	8.1%	$6914.70	—	COM	05070R104
KURA	KURA ONCOLOGY, INC.	3,047,800	$60.01B	6.7%	$12.67	+31.0%	COM	50127T109
—	ACCELERON PHARMA INC	1,449,300	$59.54B	6.6%	$18289.17	—	COM	00434H108
ASND	ASCENDIS PHARMA AS	500,000	$57.58B	6.4%	$19673.19	—	SPOSORED ADR	04351P101
—	TRICIDA, INC.	1,423,998	$56.19B	6.2%	$39460.03	—	COM	89610F101
ACAD	ACADIA PHARMACEUTICALS, INC.	1,500,000	$40.09B	4.5%	$18.73	+36.4%	COM	004225108
—	MIRATI THERAPEUTICS INC.	300,000	$30.9B	3.4%	$103000.00	—	Put	60468T105
—	MIRATI THERAPEUTICS INC.	300,000	$30.9B	3.4%	$103000.00	—	COM	60468T105
—	ZYMEWORKS INC.	1,064,041	$23.41B	2.6%	$21698.24	—	COM	98985W102
—	RETROPHIN INC.	1,003,600	$20.16B	2.2%	$20089.68	—	COM	761299106
—	MIRATII THERAPEUTICS INC.	175,000	$18.02B	2.0%	$103000.00	—	Call	60468T105
PRTA	PROTHENA CORPORATION PLC	1,676,250	$17.72B	2.0%	$10.27	0.0%	COM	G72800108
—	BIOHAVEN PHARMACEUTICAL HOLDING CO LTD.	350,000	$15.33B	1.7%	$43791.43	—	COM	G11196105
—	MILLENDO THERAPEUTICS, INC.	1,288,093	$14.89B	1.7%	$7.95	—	COM	60040X103
—	DERMIRA INC.	1,552,900	$14.85B	1.6%	$338.76	—	COM	24983L104
—	ZOGENIX, INC.	300,000	$14.33B	1.6%	$11839.82	—	Put	98978L204
GNFTY	GENFIT	694,253	$13.71B	1.5%	$24.00	—	ADS	372279109
—	MENLO THERAPEUTICS INC.	1,733,882	$10.39B	1.2%	$7.51	—	COM	586858102
—	BIOHAVEN PHARMACEUTICAL HOLDING CO. LTD.	200,000	$8.758B	1.0%	$43791.43	—	Put	G11196105
—	FOAMIX PHARMACEUTICALS LTD	2,110,071	$5.022B	0.6%	$7.50	—	COM	M46135105
IOVA	IOVANCE BIOTHERAPETUICS, INC.	200,000	$4.904B	0.5%	$9.91	+52.0%	Call	462260100
—	MOMENTA PHARMACEUTICALS, INC.	342,064	$4.259B	0.5%	$1196.13	—	COM	60877T100
RVLPQ	OSMOTICA PHARMACEUTICALS PLC	926,933	$3.522B	0.4%	$8.00	-58.5%	COM	G6S41R101
—	PROTEOSTASIS THERAPEUTICS INC.	3,500,000	$3.416B	0.4%	$2.98	—	COM	74373B109
—	FIVE PRIME THERAPEUTICS, INC.	547,712	$3.303B	0.4%	$6226.03	—	COM	33830X104
—	ZAFGEN INC.	2,211,194	$2.631B	0.3%	$9.93	—	COM	98885E103
—	STREAMLINE HEALTH SOLUTNS, INC.	130,137	$197M	0.0%	$6.45	—	COM	86323X106