Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: Feb 16, 2021
Total Value: $1.68B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NTRA | Natera | 3,100,560 | $309M | 18.4% | $99.52 * | $9.81 | +751.8% | COMM | 632307104 |
| — | Karuna Therapeutics, Inc. | 1,952,441 | $198M | 11.8% | $101.59 | $26.41 | — | COMM | 48576A100 |
| ASND | Ascendis Pharma A/S | 1,109,874 | $185M | 11.0% | $166.78 | $69.98 | — | ADR | 04351P101 |
| — | Y-mAbs Therapeutics, Inc | 2,194,278 | $109M | 6.5% | $49.51 | $26.75 | — | COMM | 984241109 |
| UTHR | United Therapeutics Corp | 347,901 | $52.81M | 3.1% | $151.79 * | $94.24 | +39.3% | COMM | 91307C102 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $52.62M | 3.1% | $14.59 | $11.51 | — | COMM | 162818108 |
| AZN | AstraZeneca PLC | 842,600 | $42.12M | 2.5% | $49.99 | $49.99 | — | ADR | 046353108 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $41.86M | 2.5% | $20.64 | $26.29 | — | COMM | 45790W108 |
| AMGN | Amgen Inc | 164,663 | $37.86M | 2.3% | $229.92 * | $205.28 | -4.4% | COMM | 031162100 |
| JAZZ | Jazz Pharmaceuticals PLC | 212,911 | $35.14M | 2.1% | $165.05 * | $125.47 | +18.7% | COMM | G50871105 |
| XLV | Health Care Select Sector SPDR | 300,000 | $34.03M | 2.0% | $113.44 | — | — | Put | 81369Y209 |
| GRTX | Galera Therapeutics, Inc | 3,083,712 | $31.55M | 1.9% | $10.23 * | $12.19 | -10.3% | COMM | 36338D108 |
| ABBV | Abbvie Inc | 293,596 | $31.46M | 1.9% | $107.15 * | $71.54 | +10.3% | COMM | 00287Y109 |
| — | Akouos, Inc | 1,515,074 | $30.04M | 1.8% | $19.83 | $22.50 | — | ADR | 00973J101 |
| — | Nextcure, Inc | 2,671,856 | $29.12M | 1.7% | $10.90 | $10.90 | — | COMM | 00653E112 |
| — | Intra-Cellular Therapies Inc | 848,162 | $26.97M | 1.6% | $31.80 | $27.53 | — | COMM | 46116X101 |
| IWM | iShares Russell 2000 ETF | 130,000 | $25.49M | 1.5% | $196.06 | — | — | Put | 464287655 |
| — | Nucana Biomed Ltd | 5,599,999 | $25.14M | 1.5% | $4.49 | $9.47 | — | ADR | 67022C106 |
| — | Merus N.V. | 1,311,039 | $22.98M | 1.4% | $17.53 | $18.53 | — | COMM | N5749R100 |
| PTCT | PTC Therapeutics Inc | 316,478 | $19.32M | 1.1% | $61.03 * | $43.59 | +35.2% | COMM | 69366J200 |
| — | Reata Pharmaceuticals Inc | 148,937 | $18.41M | 1.1% | $123.62 | $116.68 | — | COMM | 75615P103 |
| — | Athira Pharma, Inc. | 509,168 | $17.44M | 1.0% | $34.25 | $18.46 | — | COMM | 04746L104 |
| — | Otonomy Inc | 2,620,668 | $16.96M | 1.0% | $6.47 | $3.81 | — | COMM | 68906L105 |
| — | Horizon Therapeutics PLC | 213,390 | $15.61M | 0.9% | $73.15 | $73.15 | — | COMM | G46188101 |
| — | Protagonist Therapeutics Inc | 724,904 | $14.61M | 0.9% | $20.16 | $20.16 | — | COMM | 00744E106 |
| BMRN | Biomarin Pharmaceutical Inc | 164,545 | $14.43M | 0.9% | $87.69 * | $95.51 | -17.0% | COMM | 09061G101 |
| ACRS | Aclaris Therapeutics | 1,911,573 | $12.37M | 0.7% | $6.47 * | $19.07 | -77.9% | COMM | 00461U105 |
| RGNX | Regenxbio Inc | 271,114 | $12.3M | 0.7% | $45.36 * | $34.43 | +1.5% | COMM | 75901B107 |
| — | GW Pharmaceuticals PLC | 100,762 | $11.63M | 0.7% | $115.41 | $100.55 | — | ADR | 36197T103 |
| — | Nucana Biomed Ltd | 2,400,000 | $10.78M | 0.6% | $4.49 | $5.41 | — | Ordinary Shares | GBOOBYWYV |
| CYTK | Cytokinetics Inc | 508,394 | $10.56M | 0.6% | $20.78 * | $20.33 | -10.1% | COMM | 23282W605 |
| MGNX | MacroGenics Inc | 458,807 | $10.49M | 0.6% | $22.86 | $23.02 | 0.0% | COMM | 556099109 |
| — | TCR2 Therapeutics Inc | 333,707 | $10.32M | 0.6% | $30.93 | $25.43 | — | COMM | 87808K106 |
| INSM | Insmed Inc | 309,662 | $10.31M | 0.6% | $33.29 * | $24.78 | +47.4% | COMM | 457669307 |
| — | ObsEva SA | 4,749,623 | $9.879M | 0.6% | $2.08 | $13.49 | — | COMM | H5861P103 |
| — | Arena Pharmaceuticals Inc | 121,373 | $9.325M | 0.6% | $76.83 | $73.99 | — | COMM | 040047607 |
| SRPT | Sarepta Therapeutics Inc | 51,848 | $8.84M | 0.5% | $170.50 * | $148.17 | 0.0% | COMM | 803607100 |
| ACAD | ACADIA Pharmaceuticals Inc | 164,625 | $8.801M | 0.5% | $53.46 * | $47.72 | +4.0% | COMM | 004225108 |
| BCRX | BioCryst Pharmaceuticals Inc | 1,122,800 | $8.365M | 0.5% | $7.45 * | $4.01 | +28.5% | COMM | 09058V103 |
| SNDX | Syndax Pharmaceuticals Inc | 372,909 | $8.293M | 0.5% | $22.24 * | $20.74 | 0.0% | COMM | 87164F105 |
| MIRM | Mirum Pharmaceuticals Inc | 454,974 | $7.944M | 0.5% | $17.46 * | $17.41 | +12.9% | COMM | 604749101 |
| CHRS | Coherus BioSciences | 434,555 | $7.553M | 0.4% | $17.38 * | $10.94 | +62.7% | COMM | 19249H103 |
| — | ChemoCentryx Inc | 113,213 | $7.01M | 0.4% | $61.92 | $49.89 | — | COMM | 16383L106 |
| — | Jounce Therapeutics Inc | 925,280 | $6.477M | 0.4% | $7.00 | $7.00 | — | COMM | 481116101 |
| PBYI | Puma Biotechnology Inc | 629,650 | $6.46M | 0.4% | $10.26 | $10.04 | +0.9% | COMM | 74587V107 |
| LLY | Eli Lilly and Co | 36,909 | $6.232M | 0.4% | $168.85 * | $143.90 | -1.8% | COMM | 532457108 |
| — | Amarin Corp | 1,170,584 | $5.724M | 0.3% | $4.89 | $7.81 | — | ADR | 023111206 |
| — | Aligos Therapeutics Inc | 191,061 | $5.283M | 0.3% | $27.65 | $27.65 | — | COMM | 01626L105 |
| RCUS | Arcus Biosciences Inc | 186,278 | $4.836M | 0.3% | $25.96 * | $24.20 | 0.0% | COMM | 03969F109 |
| — | Acceleron Pharma Inc | 36,688 | $4.694M | 0.3% | $127.94 | $57.73 | — | COMM | 00434H108 |
| IOVA | Iovance Biotherapeutics Inc | 100,000 | $4.64M | 0.3% | $46.40 | — | — | Put | 462260100 |
| — | Aptose Biosciences Inc | 981,135 | $4.297M | 0.3% | $4.38 | $4.38 | — | COMM | 03835T200 |
| — | IGM Biosciences Inc | 45,131 | $3.985M | 0.2% | $88.30 | $88.30 | — | COMM | 449585108 |
| KURA | Kura Oncology Inc | 120,677 | $3.941M | 0.2% | $32.66 * | $14.42 | +143.6% | COMM | 50127T109 |
| TGTX | TG Therapeutics Inc | 65,474 | $3.406M | 0.2% | $52.02 * | $12.49 | +170.5% | COMM | 88322Q108 |
| — | Marinus Pharmaceuticals Inc | 274,027 | $3.343M | 0.2% | $12.20 | $12.20 | — | COMM | 56854Q200 |
| IMTX | Immatics NV | 279,532 | $3.016M | 0.2% | $10.79 * | $10.53 | +0.1% | COMM | N44445109 |
| — | Calithera Biosciences Inc | 500,326 | $2.457M | 0.1% | $4.91 | $4.49 | — | COMM | 13089P101 |
| — | Calithera Biosciences Inc | 400,000 | $1.964M | 0.1% | $4.91 | $4.49 | — | Put | 13089P101 |
| — | Zogenix Inc | 89,579 | $1.791M | 0.1% | $19.99 | $19.99 | — | COMM | 98978L204 |
| — | Synlogic Inc. | 574,972 | $1.242M | 0.1% | $2.16 | $9.38 | — | COMM | 87166L100 |
| FATE | Fate Therapeutics Inc | 13,497 | $1.227M | 0.1% | $90.91 * | $34.92 | +77.9% | COMM | 31189P102 |
| — | Kadmon Holdings Inc | 228,893 | $950K | 0.1% | $4.15 | $2.74 | — | COMM | 48283N106 |
| — | Calithera Biosciences Inc | 175,000 | $860K | 0.1% | $4.91 | $4.49 | — | Call | 13089P101 |
| REPL | Replimune Group Inc | 20,000 | $763K | 0.0% | $38.15 * | $41.67 | 0.0% | COMM | 76029N106 |
| LQDA | Liquidia Corp | 147,744 | $436K | 0.0% | $2.95 * | $7.59 | -51.6% | COMM | 53635D202 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $305K | 0.0% | $2.14 * | $8.36 | -73.8% | COMM | 70465T107 |
| BCAB | Bioatla Inc | 3,000 | $102K | 0.0% | $34.00 | $33.43 | 0.0% | COMM | 09077B104 |