Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q1 2021 (← Previous) (Next →)
Filing Date: May 14, 2021
Total Value: $1.663B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| NTRA | Natera | 3,100,560 | $315M | 18.9% | $9.81 | +1017.1% | COMM | 632307104 |
| — | Karuna Therapeutics, Inc. | 1,952,441 | $235M | 14.1% | $26.41 | — | COMM | 48576A100 |
| — | Bolt Biotherapeutics, Inc. | 2,754,437 | $90.65M | 5.4% | $32.91 | — | COMM | 097702104 |
| ASND | Ascendis Pharma A/S | 521,923 | $67.27M | 4.0% | $69.98 | — | ADR | 04351P101 |
| — | Y-mAbs Therapeutics, Inc | 2,194,278 | $66.36M | 4.0% | $26.75 | — | COMM | 984241109 |
| AZN | AstraZeneca PLC | 1,035,732 | $51.5M | 3.1% | $49.94 | — | ADR | 046353108 |
| — | Health Care Select Sector SPDR | 400,000 | $46.7M | 2.8% | — | — | Put | 81369Y959 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $43.78M | 2.6% | $11.51 | — | COMM | 162818108 |
| JAZZ | Jazz Pharmaceuticals PLC | 255,928 | $42.07M | 2.5% | $132.04 | +24.6% | COMM | G50871105 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $40.16M | 2.4% | $26.29 | — | COMM | 45790W108 |
| UTHR | United Therapeutics Corp | 215,054 | $35.97M | 2.2% | $94.24 | +76.9% | COMM | 91307C102 |
| LLY | Eli Lilly and Co | 180,501 | $33.72M | 2.0% | $177.44 | +4.9% | COMM | 532457108 |
| — | Nucana Biomed Ltd | 5,599,999 | $27.94M | 1.7% | $9.47 | — | ADR | 67022C106 |
| — | Merus N.V. | 1,311,039 | $27.39M | 1.6% | $18.53 | — | COMM | N5749R100 |
| GRTX | Galera Therapeutics, Inc | 3,083,712 | $27.2M | 1.6% | $12.19 | -10.0% | COMM | 36338D108 |
| — | Nextcure, Inc | 2,671,856 | $26.75M | 1.6% | $10.01 | — | COMM | 65343E108 |
| ALGN | Align Technology Inc | 45,500 | $24.64M | 1.5% | $552.79 | 0.0% | COMM | 016255101 |
| — | Acceleron Pharma Inc | 178,538 | $24.21M | 1.5% | $119.61 | — | COMM | 00434H108 |
| — | Reata Pharmaceuticals Inc | 238,520 | $23.78M | 1.4% | $110.30 | — | COMM | 75615P103 |
| — | Mirati Therapeutics Inc | 138,030 | $23.64M | 1.4% | $171.30 | — | COMM | 60468T105 |
| — | Intra-Cellular Therapies Inc | 655,001 | $22.22M | 1.3% | $27.53 | — | COMM | 46116X101 |
| PTCT | PTC Therapeutics Inc | 466,840 | $22.11M | 1.3% | $48.68 | +22.0% | COMM | 69366J200 |
| INSM | Insmed Inc | 618,950 | $21.08M | 1.3% | $31.50 | +21.3% | COMM | 457669307 |
| — | Akouos, Inc | 1,515,074 | $21.01M | 1.3% | $22.50 | — | COMM | 00973J101 |
| — | Gilead Sciences Inc | 300,000 | $19.39M | 1.2% | — | — | Call | 375558903 |
| EXEL | Exelixis Inc | 839,181 | $18.96M | 1.1% | $22.58 | 0.0% | COMM | 30161Q104 |
| PTGX | Protagonist Therapeutics Inc | 654,900 | $16.96M | 1.0% | $25.31 | 0.0% | COMM | 74366E102 |
| — | ObsEva SA | 4,749,623 | $15.44M | 0.9% | $13.49 | — | COMM | H5861P103 |
| QURE | Uniqure NV | 427,122 | $14.39M | 0.9% | $35.84 | 0.0% | COMM | N90064101 |
| RGNX | Regenxbio Inc | 361,735 | $12.34M | 0.7% | $36.49 | +16.9% | COMM | 75901B107 |
| — | Horizon Therapeutics PLC | 133,997 | $12.33M | 0.7% | $73.15 | — | COMM | G46188101 |
| — | Nucana Biomed Ltd | 2,400,000 | $11.98M | 0.7% | $4.99 | — | Ordinary Shares | GB00BYWYV |
| VRTX | Vertex Pharmaceuticals Inc | 45,700 | $9.82M | 0.6% | $219.65 | 0.0% | COMM | 92532F100 |
| DXCM | Dexcom Inc | 27,000 | $9.704M | 0.6% | $93.87 | 0.0% | COMM | 252131107 |
| AMGN | Amgen Inc | 38,868 | $9.671M | 0.6% | $205.28 | -0.3% | COMM | 031162100 |
| — | Agenus Inc | 3,478,201 | $9.461M | 0.6% | $2.72 | — | COMM | 00847G705 |
| MIRM | Mirum Pharmaceuticals Inc | 476,401 | $9.442M | 0.6% | $17.49 | +9.4% | COMM | 604749101 |
| — | Athira Pharma, Inc. | 509,168 | $9.369M | 0.6% | $18.46 | — | COMM | 04746L104 |
| — | ChemoCentryx Inc | 179,999 | $9.223M | 0.6% | $50.39 | — | COMM | 16383L106 |
| CYTK | Cytokinetics Inc | 389,720 | $9.065M | 0.5% | $20.33 | +5.0% | COMM | 23282W605 |
| — | ChemoCentryx Inc | 150,000 | $7.686M | 0.5% | — | — | Put | 16383L956 |
| — | TCR2 Therapeutics Inc | 336,682 | $7.434M | 0.4% | $25.43 | — | COMM | 87808K106 |
| — | Amarin Corp | 1,170,584 | $7.269M | 0.4% | $7.81 | — | ADR | 023111206 |
| SNDX | Syndax Pharmaceuticals Inc | 298,644 | $6.678M | 0.4% | $20.74 | +8.9% | COMM | 87164F105 |
| CHRS | Coherus BioSciences | 434,555 | $6.349M | 0.4% | $10.94 | +55.2% | COMM | 19249H103 |
| — | Arena Pharmaceuticals Inc | 91,448 | $6.346M | 0.4% | $73.99 | — | COMM | 040047607 |
| — | Marinus Pharmaceuticals Inc | 370,351 | $5.733M | 0.3% | $13.05 | — | COMM | 56854Q200 |
| — | Jounce Therapeutics Inc | 511,822 | $5.256M | 0.3% | $7.00 | — | COMM | 481116101 |
| PODD | Insulet Corp | 17,500 | $4.566M | 0.3% | $267.81 | 0.0% | COMM | 45784P101 |
| FATE | Fate Therapeutics Inc | 54,795 | $4.518M | 0.3% | $80.81 | +18.6% | COMM | 31189P102 |
| REPL | Replimune Group Inc | 142,209 | $4.339M | 0.3% | $38.04 | -1.6% | COMM | 76029N106 |
| IMTX | Immatics NV | 385,099 | $4.317M | 0.3% | $10.75 | +5.5% | COMM | N44445109 |
| — | Aligos Therapeutics Inc | 185,532 | $4.219M | 0.3% | $27.65 | — | COMM | 01626L105 |
| — | Aptose Biosciences Inc | 696,928 | $4.164M | 0.3% | $4.38 | — | COMM | 03835T200 |
| — | Heron Therapeutics Inc | 250,000 | $4.053M | 0.2% | — | — | Call | 427746902 |
| BCRX | BioCryst Pharmaceuticals Inc | 378,774 | $3.852M | 0.2% | $4.01 | +157.0% | COMM | 09058V103 |
| SVRA | Savara Inc | 1,737,450 | $3.614M | 0.2% | $1.71 | 0.0% | COMM | 805111101 |
| PBYI | Puma Biotechnology Inc | 344,917 | $3.353M | 0.2% | $10.04 | +11.2% | COMM | 74587V107 |
| — | Otonomy Inc | 1,251,256 | $3.191M | 0.2% | $3.81 | — | COMM | 68906L105 |
| KURA | Kura Oncology Inc | 83,164 | $2.351M | 0.1% | $14.42 | +119.3% | COMM | 50127T109 |
| MGNX | MacroGenics Inc | 73,201 | $2.331M | 0.1% | $23.02 | +5.5% | COMM | 556099109 |
| — | Synlogic Inc. | 574,972 | $2.058M | 0.1% | $9.38 | — | COMM | 87166L100 |
| — | Calithera Biosciences Inc | 757,533 | $1.833M | 0.1% | $3.79 | — | COMM | 13089P101 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $649K | 0.0% | $8.36 | -51.9% | COMM | 70465T107 |