Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	SPI ENERGY CO LTD	5,568	$70.36M	13.7%	—	—	Put	G8651P950
—	ISHARES RUSSELL 2000	2,104	$46.49M	9.0%	—	—	Put	464287955
—	BIOGEN INC	1,518	$42.47M	8.3%	—	—	Call	09062X903
—	SPDR SERIES TRUST	2,449	$33.22M	6.5%	—	—	Put	78464A950
—	SPDR S&P 500 ETF TR	834	$33.05M	6.4%	—	—	Put	78462F953
—	BARCLAYS BANK PLC	14,336	$16.34M	3.2%	—	—	Call	06746P901
—	SPDR GOLD TRUST	966	$15.45M	3.0%	—	—	Call	78463V907
—	SORRENTO THERAPEUTICS INC	18,306	$15.14M	2.9%	—	—	Put	83587F952
SRNE	SORRENTO THERAPEUTICS INC	1,064,933	$8.807M	1.7%	$10.56	0.0%	COM	83587F202
—	PENN NATIONAL GAMING INC	731	$7.664M	1.5%	—	—	Put	707569959
—	SECOND SIGHT MEDICAL PRODS INC	922,193	$7.608M	1.5%	$8.25	—	COM	81362J209
—	ASENSUS SURGICAL INC	2,301,061	$7.478M	1.5%	$3.25	—	COM	04367G103
—	NEWAGE INC	2,364,694	$6.763M	1.3%	$2.86	—	COM	650194103
—	KANDI TECHNOLOGIES GROUP INC	10,737	$6.711M	1.3%	—	—	Put	483709951
—	WIMI HOLOGRAM CLOUD INC	980,786	$6.473M	1.3%	$6.60	—	ADS	97264L100
—	BARCLAYS BANK PLC	525,000	$5.985M	1.2%	$11.40	—	ETF	06746P621
—	CBAK ENERGY TECHNOLOGY	11,632	$5.932M	1.2%	—	—	Put	14986C952
—	MOGO INC	6,302	$5.357M	1.0%	—	—	Put	60800C959
—	RIOT BLOCKCHAIN INC	900	$4.794M	0.9%	—	—	Put	767292955
—	KEMPHARM INC	5,023	$4.621M	0.9%	—	—	Put	488445956
—	REDHILL BIOPHARMA LTD	631,287	$4.621M	0.9%	$7.32	—	ADS	757468103
PENN	PENN NATIONAL GAMING INC	40,399	$4.235M	0.8%	$110.76	0.0%	COM	707569109
—	KEMPHARM INC	4,193	$3.858M	0.8%	—	—	Call	488445906
—	IONIS PHARMACEUTICALS	830	$3.732M	0.7%	—	—	Put	462222950
PCVX	VAXCYTE INC	178,992	$3.535M	0.7%	$25.16	0.0%	COM	92243G108
—	MMTEC INC	1,350,870	$3.458M	0.7%	$2.56	—	SHS	G6181K106
VTSI	VIRTRA INC	561,088	$3.451M	0.7%	$4.75	0.0%	COM	92827K301
—	AMARIN CORP PLC	5,533	$3.436M	0.7%	—	—	Call	023111906
—	NUZEE INC	965,139	$3.368M	0.7%	$3.49	—	COM	67073S208
—	HUMANCO ACQUISITION CORP	336,211	$3.345M	0.7%	$9.95	—	COM	44487N109
—	REWALK ROBOTICS LTD	1,291,893	$3.126M	0.6%	$2.26	—	SHS	M8216Q200
—	9 METERS BIOPHARMA INC	26,197	$3.065M	0.6%	—	—	Put	654405959
AUTL	AUTOLUS THERAPEUTICS LTD	525,230	$3.01M	0.6%	$5.73	—	ADS	05280R100
—	BIOGEN INC	100	$2.798M	0.5%	—	—	Put	09062X953
—	ASLAN PHARMACEUTICALS	817,165	$2.738M	0.5%	$3.35	—	ADS	04522R101
—	CEL-SCI CORP	1,760	$2.677M	0.5%	—	—	Call	150837907
—	ATOSSA THERAPEUTICS INC	12,673	$2.674M	0.5%	—	—	Put	04962H956
—	EKSO BIONICS HLDGS INC	423,360	$2.612M	0.5%	$6.17	—	COM	282644301
—	CLEVELAND BIOLABS INC	478,941	$2.514M	0.5%	$5.25	—	COM	185860202
—	MIRATI THERAPEUTICS INC	145	$2.484M	0.5%	—	—	Call	60468T905
IONS	IONIS PHARMACEUTICALS	54,688	$2.459M	0.5%	$55.77	0.0%	COM	462222100
RVPH	REVIVA PHARMACEURICALS HLDGS INC	418,437	$2.402M	0.5%	$10.02	-16.8%	COM	76152G100
—	XPRESSPA GROUP INC	12,967	$2.386M	0.5%	—	—	Put	98420U953
—	CALADRIUS BIOSCIENCES INC	11,954	$2.307M	0.4%	—	—	Put	128058953
—	ASENSUS SURGICAL INC	6,959	$2.262M	0.4%	—	—	Put	04367G953
—	MOGO INC	265,828	$2.26M	0.4%	$8.50	—	COM	60800C109
—	CEL-SCI CORP	1,448	$2.202M	0.4%	—	—	Put	150837957
—	ODONATE THERAPEUTICS INC	634,728	$2.171M	0.4%	$4.63	—	COM	676079106
—	TRILLIUM THERAPEUTICS INC	199,569	$2.143M	0.4%	$13.13	—	COM	89620X506
—	ASENSUS SURGICAL INC	6,556	$2.131M	0.4%	—	—	Call	04367G903
—	SEANERGY MARITIME HLDGS CORP	1,994,783	$2.114M	0.4%	$1.06	—	SHS	Y73760194
—	OCULAR THERAPEUTIX INC	1,230	$2.018M	0.4%	—	—	Put	67576A950
—	IONIS PHARMACEUTICALS	428	$1.924M	0.4%	—	—	Call	462222900
—	APPLIED GENETIC TECHNOLOGIES	3,775	$1.914M	0.4%	—	—	Put	03820J950
—	TRICIDA INC	354,755	$1.877M	0.4%	$6.28	—	COM	89610F101
AFIB	ACUTUS MEDICAL INC	132,522	$1.772M	0.3%	$26.41	-14.8%	COM	005111109
—	ORAMED PHARMACEUTICALS INC	1,686	$1.713M	0.3%	—	—	Put	68403P953
INFIQ	INFINITY PHARMACEUTICALS INC	530,000	$1.712M	0.3%	$3.34	0.0%	COM	45665G303
—	BRAINSTORM CELL	4,424	$1.694M	0.3%	—	—	Put	10501E951
—	DIGITAL ALLY INC	10,220	$1.666M	0.3%	—	—	Put	25382P958
—	EXELA TECHNOLOGIES	750,000	$1.635M	0.3%	$2.18	—	COM	30162V409
—	VINCERX PHARMA INC	82,948	$1.601M	0.3%	$19.30	—	COM	92731L106
—	OCULAR THERAPEUTIX INC	966	$1.585M	0.3%	—	—	Call	67576A900
—	AMPLITECH GROUP INC	342,425	$1.5M	0.3%	$4.38	—	*W	03211Q119
—	PAINREFORM LTD	330,000	$1.459M	0.3%	$4.45	—	SHS	M77798102
—	MIRATI THERAPEUTICS INC	8,500	$1.456M	0.3%	$188.37	—	COM	60468T105
DXR	DAXOR CORP	118,736	$1.437M	0.3%	$16.69	-24.2%	COM	239467103
—	ADITX THERAPEUTICS INC	5,423	$1.383M	0.3%	—	—	Put	007025959
—	OCEAN POWER TECHNOLOGIES INC	4,153	$1.375M	0.3%	—	—	Put	674870956
—	ARK	114	$1.367M	0.3%	—	—	Put	00214Q954
—	SAGE THERAPEUTICS INC	166	$1.243M	0.2%	—	—	Put	78667J958
—	WIMI HOLOGRAM CLOUD INC	1,838	$1.213M	0.2%	—	—	Put	97264L950
XBI	SPDR SERIES TRUST	8,735	$1.185M	0.2%	$135.66	—	ETF	78464A870
—	BIOPHYTIS SA	92,345	$1.182M	0.2%	$12.80	—	ADS	09076G104
—	DIGITAL ALLY INC	692,350	$1.129M	0.2%	$1.63	—	COM	25382P208
AUPH	AURINIA PHARMACEUTICALS	85,625	$1.112M	0.2%	$15.03	-3.4%	COM	05156V102
—	THERAPEUTICSMD INC	800,000	$1.072M	0.2%	$1.34	—	COM	88338N107
—	ARCADIA BIOSCIENCES INC	3,820	$1.052M	0.2%	—	—	Put	039014954
—	AMARIN CORP PLC	169,136	$1.05M	0.2%	$6.21	—	ADR	023111206
SPIEF	SPI ENERGY CO LTD	131,898	$989K	0.2%	$9.04	0.0%	SHS	G8651P110
RIOT	RIOT BLOCKCHAIN INC	18,000	$959K	0.2%	$40.49	0.0%	COM	767292105
—	VIRPAX PHARMACEUTICALS INC	200,000	$942K	0.2%	$4.71	—	COM	928251107
—	CALADRIUS BIOSCIENCES INC	484,970	$936K	0.2%	$1.93	—	COM	128058203
—	MACROGENICS INC	288	$917K	0.2%	—	—	Call	556099909
—	CURIS INC	985	$912K	0.2%	—	—	Call	231269900
—	REWALK ROBOTICS LTD	3,449	$835K	0.2%	—	—	Put	M8216Q950
—	PLURISTEM THERAPEUTICS INC	1,739	$830K	0.2%	—	—	Put	72940R950
—	PURPLE BIOTECH LTD	1,948	$805K	0.2%	—	—	Put	74638P959
—	CONTRAFECT CORP	166,175	$798K	0.2%	$4.80	—	COM	212326300
—	HUMANCO ACQUISITION CORP	67,974	$717K	0.1%	$11.02	—	UNIT	44487N208
—	LEXARIA BIOSCIENCE CORP	291,000	$695K	0.1%	$2.39	—	*W	52886N117
—	TRILLIUM THERAPEUTICS INC	646	$694K	0.1%	—	—	Call	89620X906
—	AETERNA ZENTARIS INC	598,442	$682K	0.1%	$1.14	—	COM	007975402
—	BUTTERFLY NETWORK INC	397	$668K	0.1%	—	—	Call	124155902
—	9 METERS BIOPHARMA INC	564,527	$661K	0.1%	$1.17	—	COM	654405109
—	DIGINEX LTD	592	$649K	0.1%	—	—	Put	Y2074E959
—	CELLECTAR BIOSCIENCES INC	389,061	$626K	0.1%	$2.08	—	COM	15117F500
—	TRILLIUM THERAPEUTICS INC	582	$625K	0.1%	—	—	Put	89620X956
—	BRIACELL THERAPEUTICS	160,182	$618K	0.1%	$3.86	—	COM	10778Y302
—	AURINIA PHARMACEUTICALS	469	$609K	0.1%	—	—	Call	05156V902
—	MACROGENICS INC	182	$580K	0.1%	—	—	Put	556099959
—	HEPION PHARMACEUTICALS INC	306,338	$564K	0.1%	$1.84	—	COM	426897104
—	CITIUS PHARMACEUTICALS INC	314,000	$559K	0.1%	$1.78	—	COM	17322U207
BFLY	BUTTERFLY NETWORK INC	33,047	$556K	0.1%	$19.79	0.0%	COM	124155102
—	BIO-KEY INTL INC	1,566	$547K	0.1%	—	—	Put	09060C958
—	BIOCEPT INC	1,037	$528K	0.1%	—	—	Put	09072V951
—	THE9 LTD	168	$524K	0.1%	—	—	Call	88337K902
IWM	ISHARES RUSSELL 2000	2,372	$524K	0.1%	$220.91	—	ETF	464287655
—	BRAINSTORM CELL	136,610	$523K	0.1%	$3.83	—	COM	10501E201
—	ATOSSA THERAPEUTICS INC	242,237	$511K	0.1%	$2.11	—	COM	04962H506
—	BIO PATH HLDGS INC	71,920	$505K	0.1%	$7.02	—	COM	09057N300
—	MEATECH 3D LTD	53,695	$501K	0.1%	$9.33	—	ADS	583435102
—	THE9 LTD	156	$487K	0.1%	—	—	Put	88337K952
—	STEALTH BIOTHERAPEUTICS CORP	301,575	$473K	0.1%	$1.57	—	ADS	85789A105
—	AVEO PHARMACEUTICALS INC	620	$454K	0.1%	—	—	Put	053588957
—	PHIO PHARMACEUTICALS INC	1,591	$427K	0.1%	—	—	Put	71880W953
—	ADITX THERAPEUTICS INC	166,363	$424K	0.1%	$2.55	—	COM	007025109
—	SALARIUS PHARMACEUTICALS INC	266,955	$395K	0.1%	$1.48	—	COM	79400X107
—	UCOMMUNE INTL LTD	128,564	$386K	0.1%	$3.00	—	COM	G9449A100
—	NEMAURA MEDICAL INC	501	$383K	0.1%	—	—	Put	640442958
—	TITAN PHARMACEUTICALS INC	1,263	$376K	0.1%	—	—	Put	888314956
—	BIOCEPT INC	61,464	$313K	0.1%	$4.75	—	COM	09072V501
—	ADAMIS PHARMACEUTICALS CORP	3,034	$285K	0.1%	—	—	Put	00547W958
—	NABRIVA THERAPEUTICS PLC	164,007	$272K	0.1%	$2.42	—	SHS	G63637113
—	AGRIFY CORP	21,342	$266K	0.1%	$12.46	—	COM	00853E107
—	LIXTE BIOTECHNOLOGY HLDGS INC	79,735	$262K	0.1%	$3.29	—	COM	539319202
—	THE9 LTD	8,293	$259K	0.1%	$31.23	—	ADS	88337K302
—	CARDIFF ONCOLOGY INC	275	$255K	0.0%	—	—	Call	14147L908
—	HEPION PHARMACEUTICALS INC	1,382	$254K	0.0%	—	—	Put	426897954
—	PLURISTEM THERAPEUTICS INC	50,822	$242K	0.0%	$4.76	—	COM	72940R300
—	POLARITYTE INC	210,562	$234K	0.0%	$0.68	—	COM	731094108
—	COLLPLANT BIOTECHNOLOGIES LTD	17,045	$229K	0.0%	$13.44	—	ADS	19516R107
—	AETERNA ZENTARIS INC	1,994	$227K	0.0%	—	—	Put	007975952
—	INFINITY PHARMACEUTICALS INC	679	$219K	0.0%	—	—	Call	45665G903
—	AMARIN CORP PLC	322	$200K	0.0%	—	—	Put	023111956
—	ARCADIA BIOSCIENCES INC	67,136	$185K	0.0%	$2.88	—	COM	039014204
—	HUMANCO ACQUISITION CORP	141,136	$183K	0.0%	$1.30	—	*W	44487N117
—	IT TECH PACKAGING INC	2,684	$177K	0.0%	—	—	Put	46527C950
—	VASCULAR BIOGENICS LTD	825	$165K	0.0%	—	—	Put	M96883959
—	INTEC PHARMA LTD	37,501	$164K	0.0%	$4.12	—	SHS	M53644148
—	REVIVA PHARMACEURICALS HLDGS INC	350,000	$161K	0.0%	$0.46	—	*W	76152G118
—	CARDIFF ONCOLOGY INC	169	$156K	0.0%	—	—	Put	14147L958
OCUL	OCULAR THERAPEUTIX INC	9,250	$152K	0.0%	$19.26	0.0%	COM	67576A100
—	POLARITYTE INC	1,355	$150K	0.0%	—	—	Put	731094958
—	LIXTE BIOTECHNOLOGY HLDGS INC	157,374	$128K	0.0%	$0.90	—	*W	539319111
—	BIO-KEY INTL INC	33,487	$117K	0.0%	$3.49	—	COM	09060C408
—	TANZANIAN GOLD CORP	1,515	$89,000	0.0%	—	—	Put	87601A957
—	AVEO PHARMACEUTICALS INC	10,815	$79,000	0.0%	$4.95	—	COM	053588307
—	PURPLE BIOTECH LTD	18,847	$78,000	0.0%	$4.14	—	ADS	74638P109
—	NABRIVA THERAPEUTICS PLC	463	$77,000	0.0%	—	—	Put	G63637953
—	ACTINIUM PHARMACEUTICALS INC	100	$76,000	0.0%	—	—	Put	00507W956
—	PHIO PHARMACEUTICALS INC	23,007	$62,000	0.0%	$2.69	—	COM	71880W303
—	AETERNA ZENTARIS INC	462	$53,000	0.0%	—	—	Call	007975902
—	PHASEBIO PHARMACEUTICALS INC	15,000	$52,000	0.0%	$9.10	—	COM	717224109
—	DIGITAL ALLY INC	309	$50,000	0.0%	—	—	Call	25382P908
—	CHINA JO JO DRUGSTORES INC	25,000	$28,000	0.0%	$1.38	—	COM	16949A206