Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ION GEOPHYSICAL CORP	3,150,000	$320M	45.1%	$101.54	—	NOTE	462044AJ7
—	SPI ENERGY CO LTD	3,714	$40.53M	5.7%	—	—	Put	G8651P950
—	ISHARES RUSSELL 2000	1,294	$29.68M	4.2%	—	—	Put	464287955
—	SORRENTO THERAPEUTICS	20,242	$19.61M	2.8%	—	—	Put	83587F952
—	SPDR S&P 500 ETF TR	434	$18.58M	2.6%	—	—	Put	78462F953
—	SPDR SERIES TRUST	1,284	$17.39M	2.5%	—	—	Put	78464A950
—	ATOSSA THERAPEUTICS INC	25,446	$16.08M	2.3%	—	—	Put	04962H956
SRNE	SORRENTO THERAPEUTICS	1,197,976	$11.61M	1.6%	$10.27	-22.5%	COM	83587F202
—	KEMPHARM INC	7,117	$9.124M	1.3%	—	—	Put	488445956
—	COCRYSTAL PHARMA INC	6,110,657	$7.638M	1.1%	$1.25	—	COM	19188J300
—	ENOCHIAN BIOSCIENCES INC	1,341,663	$6.668M	0.9%	$4.97	—	COM	29350E104
—	ATOSSA THERAPEUTICS INC	1,045,987	$6.611M	0.9%	$5.35	—	COM	04962H506
—	MOGO INC	8,183	$6.424M	0.9%	—	—	Put	60800C959
—	ATERIAN INC.	433,000	$6.329M	0.9%	$14.62	—	COM	02156U101
—	BARCLAYS BANK PLC	190,600	$5.615M	0.8%	$29.46	—	IPTH	06747R477
—	KANDI TECHNOLOGIES GROUP INC	9,267	$5.542M	0.8%	—	—	Put	483709951
—	CBAK ENERGY TECH INC	11,089	$5.223M	0.7%	—	—	Put	14986C952
—	RECON TECHNOLOGY LTD	930,000	$4.027M	0.6%	$4.33	—	SHS	G7415M124
—	HUMANCO ACQUISITION CORP	404,185	$3.945M	0.6%	$9.92	—	COM	44487N109
—	NEWAGE INC	1,729,931	$3.858M	0.5%	$2.86	—	COM	650194103
—	RIOT BLOCKCHAIN INC	1,019	$3.839M	0.5%	—	—	Put	767292955
—	MOGO INC	460,270	$3.613M	0.5%	$8.23	—	COM	60800C109
—	VINCERX PHARMA INC	271,063	$3.521M	0.5%	$14.92	—	COM	92731L106
—	BUTTERFLY NETWORK INC	2,410	$3.49M	0.5%	—	—	Call	124155902
—	WIMI HOLOGRAM CLOUD INC	626,095	$3.437M	0.5%	$6.60	—	ADS	97264L100
—	IONIS PHARMACEUTICALS	841	$3.355M	0.5%	—	—	Put	462222950
—	MIRATI THERAPEUTICS INC	193	$3.118M	0.4%	—	—	Call	60468T905
IONS	IONIS PHARMACEUTICALS	78,000	$3.111M	0.4%	$50.81	-22.9%	COM	462222100
—	CANAAN INC	3,742	$3.05M	0.4%	—	—	Put	134748952
—	DIGITAL ALLY INC NEW	16,612	$2.99M	0.4%	—	—	Put	25382P958
—	ASENSUS SURGICAL INC	931,414	$2.953M	0.4%	$3.25	—	COM	04367G103
—	MARATHON DIGITAL	912	$2.861M	0.4%	—	—	Put	565788956
—	ATERIAN INC	1,914	$2.8M	0.4%	—	—	Put	02156U951
—	AMARIN CORP PLC	6,268	$2.745M	0.4%	—	—	Call	023111906
GLBS	GLOBUS MARITIME LTD	700,427	$2.718M	0.4%	$4.55	0.0%	COM	Y27265126
PCVX	VAXCYTE INC	117,994	$2.656M	0.4%	$25.16	-18.6%	COM	92243G108
AUTL	AUTOLUS THERAPEUTICS LTD	400,050	$2.656M	0.4%	$5.73	—	ADS	05280R100
—	BARCLAYS BANK PLC	875	$2.578M	0.4%	—	—	Call	06747R907
—	ASLAN PHARMACEUTICALS LTD	765,276	$2.525M	0.4%	$3.35	—	ADS	04522R101
—	ARCADIA BIOSCIENCES INC	8,340	$2.477M	0.3%	—	—	Put	039014954
—	THE9 LTD	1,689	$2.409M	0.3%	—	—	Put	88337K952
—	KIROMIC BIOPHARMA INC	500,508	$2.407M	0.3%	$4.81	—	COM	497634105
RIOT	RIOT BLOCKCHAIN INC	63,000	$2.373M	0.3%	$37.10	-3.7%	COM	767292105
—	OCULAR THERAPEUTIX INC	1,668	$2.365M	0.3%	—	—	Call	67576A900
—	REDHILL BIOPHARMA LTD	340,440	$2.342M	0.3%	$7.32	—	ADS	757468103
—	REWALK ROBOTICS LTD	1,368,658	$2.313M	0.3%	$2.22	—	SHS	M8216Q200
—	BIT BROTHER LTD	1,039,458	$2.287M	0.3%	$2.20	—	SHS	G1144D109
—	NEWAGE INC	10,113	$2.255M	0.3%	—	—	Call	650194903
—	KEMPHARM INC	1,735	$2.224M	0.3%	—	—	Call	488445906
—	EKSO BIONICS HLDGS INC	402,873	$2.216M	0.3%	$6.17	—	COM	282644301
—	OCULAR THERAPEUTIX INC	1,558	$2.209M	0.3%	—	—	Put	67576A950
ZVRA	KEMPHARM INC	172,163	$2.207M	0.3%	$10.75	0.0%	COM	488445206
—	CLEVELAND BIOLABS INC	400,080	$2.188M	0.3%	$5.25	—	COM	185860202
—	MMTEC INC	1,003,477	$2.087M	0.3%	$2.56	—	SHS	G6181K106
—	NUZEE INC	660,044	$2.079M	0.3%	$3.49	—	COM	67073S208
—	NEMAURA MEDICAL INC	2,005	$2.075M	0.3%	—	—	Put	640442958
—	9 METERS BIOPHARMA INC	18,128	$1.994M	0.3%	—	—	Put	654405959
—	ORAMED PHARMACEUTICALS INC	1,418	$1.897M	0.3%	—	—	Put	68403P953
—	TRICIDA INC	436,500	$1.886M	0.3%	$5.92	—	COM	89610F101
—	ADOMANI INC	6,166,711	$1.821M	0.3%	$0.30	—	COM	00726A100
—	BRAINSTORM CELL	4,713	$1.791M	0.3%	—	—	Put	10501E951
—	ASENSUS SURGICAL INC	5,594	$1.773M	0.2%	—	—	Put	04367G953
AFIB	ACUTUS MEDICAL INC	103,100	$1.751M	0.2%	$26.41	-44.6%	COM	005111109
—	XPRESSPA GROUP INC	11,077	$1.706M	0.2%	—	—	Put	98420U953
—	CALADRIUS BIOSCIENCES INC	10,414	$1.677M	0.2%	—	—	Put	128058953
—	CEL-SCI CORP	1,916	$1.663M	0.2%	—	—	Put	150837957
—	WIMI HOLOGRAM CLOUD INC	2,941	$1.615M	0.2%	—	—	Put	97264L950
—	OCEAN POWER TECHS	4,180	$1.496M	0.2%	—	—	Put	674870956
—	AMARIN CORP PLC	3,384	$1.482M	0.2%	—	—	Put	023111956
—	AMARIN CORP PLC	326,975	$1.432M	0.2%	$5.33	—	ADR	023111206
—	ADITX THERAPEUTICS INC	5,414	$1.402M	0.2%	—	—	Put	007025959
—	TRILLIUM THERAPEUTICS INC	143,496	$1.392M	0.2%	$13.13	—	COM	89620X506
BIIB	BIOGEN INC	4,000	$1.385M	0.2%	$302.94	0.0%	COM	09062X103
INFIQ	INFINITY PHARMACEUTICALS	441,473	$1.32M	0.2%	$3.34	-5.2%	COM	45665G303
—	CEL-SCI CORP	145,285	$1.261M	0.2%	$8.68	—	COM	150837607
—	INHIBIKASE THERAPEUTICS INC	421,200	$1.179M	0.2%	$2.80	—	COM	45719W106
AMPG	AMPLITECH GROUP INC	229,102	$1.061M	0.1%	$5.75	0.0%	COM	03211Q200
—	BRIACELL THERAPEUTICS	196,033	$1.045M	0.1%	$4.13	—	COM	10778Y302
DXR	DAXOR CORP	97,487	$1.033M	0.1%	$16.69	-36.6%	COM	239467103
—	LEXARIA BIOSCIENCE CORP.	401,246	$1.007M	0.1%	$2.42	—	*W	52886N117
—	PURPLE BIOTECH LTD	2,063	$1.007M	0.1%	—	—	Put	74638P959
—	PAINREFORM LTD	347,468	$980K	0.1%	$4.37	—	SHS	M77798102
—	MIRATI THERAPEUTICS INC	6,000	$969K	0.1%	$188.37	—	COM	60468T105
—	BIOPHYTIS SA	91,018	$964K	0.1%	$12.80	—	ADS	09076G104
—	ATOSSA THERAPEUTICS INC	1,517	$959K	0.1%	—	—	Call	04962H906
SBEVW	SPLASH BEVERAGE GROUP INC	860,609	$947K	0.1%	$1.10	—	*W	84862C112
—	BRAINSTORM CELL	242,850	$923K	0.1%	$3.82	—	COM	10501E201
—	TRILLIUM THERAPEUTICS INC	942	$914K	0.1%	—	—	Put	89620X956
MARA	MARATHON DIGITAL	27,590	$866K	0.1%	$31.73	0.0%	COM	565788106
—	SECOND SIGHT MEDICAL PRODS INC	174,900	$864K	0.1%	$8.25	—	COM	81362J209
CBAT	CBAK ENERGY TECH INC	175,097	$825K	0.1%	$4.46	0.0%	COM	14986C102
—	THERAPEUTICSMD INC	625,000	$744K	0.1%	$1.34	—	COM	88338N107
—	CONTRAFECT CORP	166,175	$731K	0.1%	$4.80	—	COM	212326300
—	SEANERGY MARITIME HLDGS CORP	650,000	$728K	0.1%	$1.06	—	SHS	Y73760194
—	INFINITY PHARMACEUTICALS	2,418	$723K	0.1%	—	—	Call	45665G903
—	METEN EDTECHX EDUCATION LTD	733,840	$712K	0.1%	$0.97	—	ORD	G6055H114
—	VIRPAX PHARMACEUTICALS INC	154,737	$704K	0.1%	$4.71	—	COM	928251107
—	REWALK ROBOTICS LTD	4,003	$677K	0.1%	—	—	Put	M8216Q950
—	ATHERSYS INC NEW	4,321	$622K	0.1%	—	—	Call	04744L906
—	AURINIA PHARMACEUTICALS INC	469	$608K	0.1%	—	—	Call	05156V902
—	APPLIED GENETIC TECHNOLOGIES	1,545	$604K	0.1%	—	—	Put	03820J950
—	BIO-KEY INTL INC	1,587	$603K	0.1%	—	—	Put	09060C958
—	THE9 LTD	422	$602K	0.1%	—	—	Call	88337K902
—	DIGITAL ALLY INC NEW	332,375	$598K	0.1%	$1.63	—	COM	25382P208
—	ADAMIS PHARMACEUTICALS CORP	5,168	$568K	0.1%	—	—	Put	00548A956
—	AMPLITECH GROUP INC	337,599	$554K	0.1%	$4.38	—	*W	03211Q119
—	GLOBUS MARITIME LTD	1,399	$543K	0.1%	—	—	Put	Y27265956
—	THE9 LTD	36,900	$526K	0.1%	$18.07	—	ADS	88337K302
—	CELLECTAR BIOSCIENCES	426,561	$508K	0.1%	$2.00	—	COM	15117F500
—	1847 GOEDEKER INC	1,305	$502K	0.1%	—	—	Put	28252C959
—	ATHERSYS INC NEW	345,400	$497K	0.1%	$1.44	—	COM	04744L106
—	MACROGENICS INC	182	$489K	0.1%	—	—	Put	556099959
—	BIOCEPT INC	1,160	$486K	0.1%	—	—	Put	09072V951
—	ADITX THERAPEUTICS INC	185,299	$480K	0.1%	$2.55	—	COM	007025109
—	MEATECH 3D LTD	64,003	$429K	0.1%	$8.91	—	ADS	583435102
JOB	GEE GROUP INC	700,000	$401K	0.1%	$0.67	0.0%	COM	36165A102
POLWQ	1847 GOEDEKER INC	180,000	$385K	0.1%	$2.14	—	*W	28252C117
—	PHIO PHARMACEUTICALS CORP	1,621	$366K	0.1%	—	—	Put	71880W953
—	TITAN PHARMACEUTICALS INC	1,274	$331K	0.0%	—	—	Put	888314956
—	BIOCEPT INC	76,892	$322K	0.0%	$4.64	—	COM	09072V501
—	DIGINEX LTD	488	$320K	0.0%	—	—	Put	Y2074E959
OCUL	OCULAR THERAPEUTIX INC	19,217	$273K	0.0%	$17.16	-11.4%	COM	67576A100
—	SALARIUS PHARMACEUTICALS	249,033	$264K	0.0%	$1.48	—	COM	79400X107
—	PURPLE BIOTECH LTD	50,590	$247K	0.0%	$4.61	—	ADS	74638P109
—	MACROGENICS INC	92	$247K	0.0%	—	—	Call	556099909
—	CASTOR MARITIME INC	93,525	$244K	0.0%	$2.61	—	SHS	Y1146L125
—	HUMANCO ACQUISITION CORP	200,314	$238K	0.0%	$1.26	—	*W	44487N117
—	UCOMMUNE INTL LTD	100,650	$223K	0.0%	$3.00	—	COM	G9449A100
—	HEPION PHARMS INC	1,110	$220K	0.0%	—	—	Call	426897904
—	PALISADE BIO INC	52,500	$214K	0.0%	$4.08	—	COM	696389105
—	AETERNA ZENTARIS INC	244,240	$214K	0.0%	$1.14	—	COM	007975402
—	PLURISTEM THERAPEUTICS INC	531	$210K	0.0%	—	—	Put	72940R950
—	LIXTE BIOTECHNOLOGY INC	65,511	$199K	0.0%	$3.29	—	COM	539319202
—	HEPION PHARMS INC	980	$194K	0.0%	—	—	Put	426897954
—	NOVAN INC	19,132	$192K	0.0%	$10.04	—	COM	66988N205
—	CASTOR MARITIME INC	726	$189K	0.0%	—	—	Put	Y1146L955
—	HARBOR CUSTOM DEVELOPMENT IN	272,103	$171K	0.0%	$0.63	—	*W	41150T116
—	NABRIVA THERAPEUTICS PLC	1,225	$165K	0.0%	—	—	Put	G63637953
TVTX	TRAVERE THERAPEUTICS INC	10,042	$147K	0.0%	$19.72	0.0%	COM	89422G107
—	META MATERIALS INC	182	$136K	0.0%	—	—	Put	59134N954
—	TRILLIUM THERAPEUTICS INC	121	$117K	0.0%	—	—	Call	89620X906
—	REDHILL BIOPHARMA LTD	170	$117K	0.0%	—	—	Call	757468903
—	PHIO PHARMACEUTICALS CORP	51,756	$117K	0.0%	$2.45	—	COM	71880W303
—	VASCULAR BIOGENICS LTD	492	$117K	0.0%	—	—	Put	M96883959
—	CARDIFF ONCOLOGY INC	167	$111K	0.0%	—	—	Put	14147L958
—	1847 GOEDEKER INC	28,603	$110K	0.0%	$3.85	—	COM	28252C109
—	EVOFEM BIOSCIENCES INC	945	$107K	0.0%	—	—	Put	30048L954
—	LIXTE BIOTECHNOLOGY INC	140,089	$107K	0.0%	$0.90	—	*W	539319111
—	ION GEOPHYSICAL CORP	500	$105K	0.0%	—	—	Call	462044907
—	9 METERS BIOPHARMA INC	862	$95,000	0.0%	—	—	Call	654405909
—	AETERNA ZENTARIS INC	920	$81,000	0.0%	—	—	Put	007975952
—	TANZANIAN GOLD CORP	1,568	$80,000	0.0%	—	—	Put	87601A957
—	NABRIVA THERAPEUTICS PLC	57,766	$78,000	0.0%	$2.42	—	COM	G63637113
—	BIO-KEY INTL INC	16,995	$65,000	0.0%	$3.49	—	COM	09060C408
—	EVOKE PHARMA INC	47,431	$65,000	0.0%	$1.37	—	COM	30049G104
—	TRICIDA INC	146	$63,000	0.0%	$5.92	—	Call	89610F101
—	ADAMIS PHARMACEUTICALS CORP	553	$61,000	0.0%	—	—	Call	00548A906
—	IT TECH PACKAGING	1,228	$58,000	0.0%	—	—	Put	46527C950
—	ODONATE THERAPEUTICS INC	14,979	$52,000	0.0%	$4.63	—	COM	676079106
—	VASCULAR BIOGENICS LTD	198	$47,000	0.0%	—	—	Call	M96883909
—	ATHERSYS INC NEW	204	$29,000	0.0%	—	—	Put	04744L956
—	GROM SOCIAL ENTERPRISES INC	29,471	$29,000	0.0%	$0.98	—	*W	39878L118