5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 15, 2021

Total Value: $492M (100.0% shares, 0.0% debt)

Holdings (16)

— VOR BIOPHARMA INC 21.3%

Value $105M Shares 6,692,429 Est. Cost $43.10 Unrealized —

— RALLYBIO CORP 15.0%

Value $73.67M Shares 4,190,724 Est. Cost $17.58 Unrealized —

— AKOUOS INC 9.7%

Value $48.02M Shares 4,135,784 Est. Cost $22.50 Unrealized —

— HOMOLOGY MEDICINES INC 7.2%

Value $35.7M Shares 4,535,919 Est. Cost $20.70 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 7.2%

Value $35.64M Shares 1,398,066 Est. Cost $7.13 Unrealized +227.3%

— IMPEL NEUROPHARMA INC 7.1%

Value $35.14M Shares 2,884,791 Est. Cost $8.85 Unrealized —

ARVN ARVINAS INC 6.7%

Value $32.87M Shares 400,000 Est. Cost $29.28 Unrealized +201.9%

CABA CABALETTA BIO INC 5.8%

Value $28.69M Shares 2,359,263 Est. Cost $11.85 Unrealized -22.2%

CRNX CRINETICS PHARMACEUTICALS IN 5.8%

Value $28.68M Shares 1,362,286 Est. Cost $19.04 Unrealized +9.9%

— SCPHARMACEUTICALS INC 5.2%

Value $25.48M Shares 3,831,474 Est. Cost $5.92 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 2.8%

Value $13.68M Shares 555,555 Est. Cost $21.74 Unrealized 0.0%

— IVERIC BIO INC 2.5%

Value $12.51M Shares 770,000 Est. Cost $16.24 Unrealized —

JANX JANUX THERAPEUTICS INC 2.0%

Value $9.653M Shares 446,266 Est. Cost $22.27 Unrealized +29.2%

— 5 01 ACQUISITION CORP 0.7%

Value $3.586M Shares 365,126 Est. Cost $10.17 Unrealized —

— CIDARA THERAPEUTICS INC 0.5%

Value $2.541M Shares 1,134,511 Est. Cost $3.84 Unrealized —

SPRY SILVERBACK THERAPEUTICS INC 0.3%

Value $1.694M Shares 169,748 Est. Cost $24.66 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	VOR BIOPHARMA INC	6,692,429	$105M	21.3%	$43.10	—	COM	929033108
—	RALLYBIO CORP	4,190,724	$73.67M	15.0%	$17.58	—	COM	75120L100
—	AKOUOS INC	4,135,784	$48.02M	9.7%	$22.50	—	COM	00973J101
—	HOMOLOGY MEDICINES INC	4,535,919	$35.7M	7.2%	$20.70	—	COM	438083107
IDYA	IDEAYA BIOSCIENCES INC	1,398,066	$35.64M	7.2%	$7.13	+227.3%	COM	45166A102
—	IMPEL NEUROPHARMA INC	2,884,791	$35.14M	7.1%	$8.85	—	COM	45258K109
ARVN	ARVINAS INC	400,000	$32.87M	6.7%	$29.28	+201.9%	COM	04335A105
CABA	CABALETTA BIO INC	2,359,263	$28.69M	5.8%	$11.85	-22.2%	COM	12674W109
CRNX	CRINETICS PHARMACEUTICALS IN	1,362,286	$28.68M	5.8%	$19.04	+9.9%	COM	22663K107
—	SCPHARMACEUTICALS INC	3,831,474	$25.48M	5.2%	$5.92	—	COM	810648105
RNAM	AVIDITY BIOSCIENCES INC	555,555	$13.68M	2.8%	$21.74	0.0%	COM	05370A108
—	IVERIC BIO INC	770,000	$12.51M	2.5%	$16.24	—	COM	46583P102
JANX	JANUX THERAPEUTICS INC	446,266	$9.653M	2.0%	$22.27	+29.2%	COM	47103J105
—	5 01 ACQUISITION CORP	365,126	$3.586M	0.7%	$10.17	—	COM CL A	33836P105
—	CIDARA THERAPEUTICS INC	1,134,511	$2.541M	0.5%	$3.84	—	COM	171757107
SPRY	SILVERBACK THERAPEUTICS INC	169,748	$1.694M	0.3%	$24.66	0.0%	COM	82835W108