5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q4 2021 (← Previous) (Next →)

Filing Date: Feb 3, 2022

Total Value: $533M (100.0% shares, 0.0% debt)

Holdings (17)

— PEAR THERAPEUTICS INC 21.7%

Value $116M Shares 18,631,771 Est. Cost $6.20 Unrealized —

TRDA ENTRADA THERAPEUTICS INC 14.2%

Value $75.47M Shares 4,408,379 Est. Cost $17.12 Unrealized —

— VOR BIOPHARMA INC 13.9%

Value $73.92M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— RALLYBIO CORP 7.5%

Value $39.98M Shares 4,190,724 Est. Cost $17.58 Unrealized —

— AKOUOS INC 6.6%

Value $35.15M Shares 4,135,784 Est. Cost $22.50 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 6.2%

Value $33.05M Shares 1,398,066 Est. Cost $7.13 Unrealized +225.6%

ARVN ARVINAS INC 6.2%

Value $32.86M Shares 400,000 Est. Cost $29.28 Unrealized +178.0%

— IMPEL NEUROPHARMA INC 4.7%

Value $24.9M Shares 2,884,791 Est. Cost $8.85 Unrealized —

CRNX CRINETICS PHARMACEUTICALS IN 4.6%

Value $24.5M Shares 862,286 Est. Cost $19.04 Unrealized +29.5%

— SCPHARMACEUTICALS INC 3.6%

Value $19.23M Shares 3,831,474 Est. Cost $5.92 Unrealized —

— HOMOLOGY MEDICINES INC 3.1%

Value $16.51M Shares 4,535,919 Est. Cost $20.70 Unrealized —

— IVERIC BIO INC 2.0%

Value $10.76M Shares 643,248 Est. Cost $16.24 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.7%

Value $9.283M Shares 390,555 Est. Cost $21.74 Unrealized +9.9%

JANX JANUX THERAPEUTICS INC 1.7%

Value $8.805M Shares 446,266 Est. Cost $22.27 Unrealized -5.9%

CABA CABALETTA BIO INC 1.5%

Value $7.824M Shares 2,064,263 Est. Cost $11.85 Unrealized -10.0%

— 5 01 ACQUISITION CORP 0.7%

Value $3.596M Shares 365,126 Est. Cost $10.17 Unrealized —

— CIDARA THERAPEUTICS INC 0.3%

Value $1.441M Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	PEAR THERAPEUTICS INC	18,631,771	$116M	21.7%	$6.20	—	CLASS A COM	704723105
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$75.47M	14.2%	$17.12	—	COM	29384C108
—	VOR BIOPHARMA INC	6,361,723	$73.92M	13.9%	$43.10	—	COM	929033108
—	RALLYBIO CORP	4,190,724	$39.98M	7.5%	$17.58	—	COM	75120L100
—	AKOUOS INC	4,135,784	$35.15M	6.6%	$22.50	—	COM	00973J101
IDYA	IDEAYA BIOSCIENCES INC	1,398,066	$33.05M	6.2%	$7.13	+225.6%	COM	45166A102
ARVN	ARVINAS INC	400,000	$32.86M	6.2%	$29.28	+178.0%	COM	04335A105
—	IMPEL NEUROPHARMA INC	2,884,791	$24.9M	4.7%	$8.85	—	COM	45258K109
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$24.5M	4.6%	$19.04	+29.5%	COM	22663K107
—	SCPHARMACEUTICALS INC	3,831,474	$19.23M	3.6%	$5.92	—	COM	810648105
—	HOMOLOGY MEDICINES INC	4,535,919	$16.51M	3.1%	$20.70	—	COM	438083107
—	IVERIC BIO INC	643,248	$10.76M	2.0%	$16.24	—	COM	46583P102
RNAM	AVIDITY BIOSCIENCES INC	390,555	$9.283M	1.7%	$21.74	+9.9%	COM	05370A108
JANX	JANUX THERAPEUTICS INC	446,266	$8.805M	1.7%	$22.27	-5.9%	COM	47103J105
CABA	CABALETTA BIO INC	2,064,263	$7.824M	1.5%	$11.85	-10.0%	COM	12674W109
—	5 01 ACQUISITION CORP	365,126	$3.596M	0.7%	$10.17	—	COM CL A	33836P105
—	CIDARA THERAPEUTICS INC	1,134,511	$1.441M	0.3%	$3.84	—	COM	171757107