Location: New York, NY
CIK: 0001633313 · Show all filings
Period: Q1 2022 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $5.478B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | HORIZON THERAPEUTICS PLC | 6,500,000 | $684M | 12.5% | $48.54 | — | Common | G46188101 |
| UTHR | UNITED THERAPEUTICS CORP | 3,030,000 | $544M | 9.9% | $133.73 | +42.5% | Common | 91307C102 |
| APLS | APELLIS PHARMACEUTICALS INC | 9,450,000 | $480M | 8.8% | $47.78 | -7.6% | Common | 03753U106 |
| — | MIRATI THERAPEUTICS INC | 5,325,000 | $438M | 8.0% | $53.26 | — | Common | 60468T105 |
| ARGX | ARGENX SE | 1,255,000 | $396M | 7.2% | $136.82 | — | Sponsored ADR | 04016X101 |
| XBI | SPDR SERIES TRUST - S&P BIOTECH | 3,050,000 | $274M | 5.0% | $97.48 | — | ETF | 78464A870 |
| ASND | ASCENDIS PHARMA | 2,200,000 | $258M | 4.7% | $131.30 | — | Sponsored ADR | 04351P101 |
| SRPT | SAREPTA THERAPEUTICS INC | 3,135,000 | $245M | 4.5% | $99.17 | -22.8% | Common | 803607100 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 3,035,000 | $234M | 4.3% | $83.49 | +0.2% | Common | 09061G101 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,300,000 | $212M | 3.9% | $154.30 | -1.3% | Common | 02043Q107 |
| FOLD | AMICUS THERAPEUTICS INC | 20,500,000 | $194M | 3.5% | $11.11 | -15.6% | Common | 03152W109 |
| — | SEAGEN INC | 1,315,000 | $189M | 3.5% | $144.05 | — | Common | 81181C104 |
| XENE | XENON PHARMACEUTICALS INC | 4,985,000 | $152M | 2.8% | $16.29 | +83.8% | Common | 98420N105 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 9,125,000 | $152M | 2.8% | $16.43 | -5.9% | Common | 462260100 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,425,000 | $140M | 2.6% | $124.06 | -32.0% | Common | 558868105 |
| — | IVERIC BIO INC | 7,250,000 | $122M | 2.2% | $6.39 | — | Common | 46583P102 |
| KURA | KURA ONCOLOGY INC | 4,800,000 | $77.18M | 1.4% | $23.38 | -38.2% | Common | 50127T109 |
| KRYS | KRYSTAL BIOTECH INC | 1,005,000 | $66.87M | 1.2% | $60.43 | +3.3% | Common | 501147102 |
| ACAD | ACADIA PHARMACEUTICALS INC | 2,275,000 | $55.1M | 1.0% | $47.61 | -49.2% | Common | 004225108 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 3,311,434 | $46.43M | 0.8% | $20.37 | -31.8% | Common | 61225M102 |
| PMVP | PMV PHARMACEUTICALS INC | 2,200,000 | $45.8M | 0.8% | $29.39 | -40.0% | Common | 69353Y103 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 2,220,500 | $38.59M | 0.7% | $20.62 | -18.3% | Common | 87164F105 |
| DSGN | DESIGN THERAPEUTICS INC | 2,222,222 | $35.89M | 0.7% | $25.91 | -40.9% | Common | 25056L103 |
| KYMR | KYMERA THERAPEUTICS INC | 816,500 | $34.55M | 0.6% | $52.87 | -20.1% | Common | 501575104 |
| MNKD | MANNKIND CORP | 8,800,000 | $32.38M | 0.6% | $3.55 | +2.9% | Common | 56400P706 |
| — | CYMABAY THERAPEUTICS INC | 10,300,000 | $32.03M | 0.6% | $6.26 | — | Common | 23257D103 |
| WHWK | AADI BIOSCIENCES INC | 1,829,402 | $31.05M | 0.6% | $30.48 | -37.1% | Common | 00032Q104 |
| BCRX | BIOCRYST PHARMACEUTICLAS INC | 1,875,000 | $30.49M | 0.6% | $16.04 | 0.0% | Common | 09058V103 |
| — | MARINUS PHARMACEUTICALS INC | 3,150,000 | $29.45M | 0.5% | $12.20 | — | Common | 56854Q200 |
| — | MERSANA THERAPEUTICS INC | 6,800,000 | $27.13M | 0.5% | $23.19 | — | Common | 59045L106 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,300,000 | $24.01M | 0.4% | $24.59 | -30.9% | Common | 05370A108 |
| — | PRAXIS PRECISION MEDICINES INC | 2,150,000 | $21.95M | 0.4% | $36.14 | — | Common | 74006W108 |
| — | DICE THERAPEUTICS INC | 1,075,000 | $20.57M | 0.4% | $26.26 | — | Common | 23345J104 |
| — | AMARIN CORP PLC | 6,000,000 | $19.74M | 0.4% | $8.22 | — | Sponsored ADR | 023111206 |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 230,000 | $16.7M | 0.3% | $69.58 | 0.0% | Common | 90400D108 |
| NUVL | NUVALENT INC | 1,049,471 | $14.58M | 0.3% | $29.01 | -49.9% | Common | 670703107 |
| TNGX | TANGO THERAPEUTICS INC | 1,550,000 | $11.75M | 0.2% | $11.99 | -27.7% | Common | 87583X109 |
| — | AVADEL PHARMACEUTICALS PLC | 1,670,000 | $11.41M | 0.2% | $7.90 | — | Sponsored ADR | 05337M104 |
| IOBT | IO BIOTECH INC | 2,055,883 | $9.58M | 0.2% | $9.66 | -31.6% | Common | 449778109 |
| — | ADVERUM BIOTECHNOLOGIES INC | 6,950,000 | $9.105M | 0.2% | $11.14 | — | Common | 00773U108 |
| — | APPLIED MOLECULAR TRANS INC | 1,030,000 | $7.746M | 0.1% | $7.52 | — | Common | 03824M109 |
| FENC | FENNEC PHARMACEUTICALS INC | 1,200,000 | $6.72M | 0.1% | $9.85 | -48.9% | Common | 31447P100 |
| GNCAQ | GENOCEA BIOSCIENCES INC | 5,084,184 | $6.355M | 0.1% | $2.62 | -58.5% | Common | 372427401 |