5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q2 2022 (← Previous) (Next →)

Filing Date: Aug 15, 2022

Total Value: $404M (100.0% shares, 0.0% debt)

Holdings (21)

— CINCOR PHARMA INC 20.2%

Value $81.72M Shares 4,337,646 Est. Cost $17.54 Unrealized —

TRDA ENTRADA THERAPEUTICS INC 13.3%

Value $53.69M Shares 4,408,379 Est. Cost $17.12 Unrealized —

— VOR BIOPHARMA INC 7.8%

Value $31.62M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— PEAR THERAPEUTICS INC 7.1%

Value $28.69M Shares 18,631,771 Est. Cost $6.20 Unrealized —

— RALLYBIO CORP 7.0%

Value $28.17M Shares 3,730,724 Est. Cost $17.58 Unrealized —

— IMPEL NEUROPHARMA INC 6.7%

Value $26.89M Shares 2,884,791 Est. Cost $8.85 Unrealized —

— AKOUOS INC 4.8%

Value $19.4M Shares 4,135,784 Est. Cost $22.50 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 4.8%

Value $19.29M Shares 1,398,066 Est. Cost $7.13 Unrealized +55.9%

— SCPHARMACEUTICALS INC 4.2%

Value $17.17M Shares 3,561,474 Est. Cost $5.92 Unrealized —

ARVN ARVINAS INC 4.2%

Value $16.84M Shares 400,000 Est. Cost $29.28 Unrealized +71.4%

CRNX CRINETICS PHARMACEUTICALS IN 4.0%

Value $16.08M Shares 862,286 Est. Cost $19.04 Unrealized +4.8%

PHVS PHARVARIS N V 3.2%

Value $12.99M Shares 587,600 Est. Cost $18.63 Unrealized 0.0%

COGT COGENT BIOSCIENCES INC 2.5%

Value $10.19M Shares 1,129,200 Est. Cost $6.91 Unrealized -1.3%

— IVERIC BIO INC 2.4%

Value $9.888M Shares 1,027,874 Est. Cost $16.46 Unrealized —

— HOMOLOGY MEDICINES INC 2.2%

Value $8.936M Shares 4,535,919 Est. Cost $20.70 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.4%

Value $5.675M Shares 390,555 Est. Cost $21.74 Unrealized -31.5%

JANX JANUX THERAPEUTICS INC 1.3%

Value $5.449M Shares 446,266 Est. Cost $22.27 Unrealized -46.8%

— PROMETHEUS BIOSCIENCES INC 1.3%

Value $5.148M Shares 182,370 Est. Cost $28.23 Unrealized —

— 5 01 ACQUISITION CORP 0.9%

Value $3.615M Shares 365,126 Est. Cost $10.17 Unrealized —

CABA CABALETTA BIO INC 0.5%

Value $2.188M Shares 2,064,263 Est. Cost $11.85 Unrealized -88.1%

— CIDARA THERAPEUTICS INC 0.1%

Value $554K Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CINCOR PHARMA INC	4,337,646	$81.72M	20.2%	$17.54	—	COM	17240Y109
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$53.69M	13.3%	$17.12	—	COM	29384C108
—	VOR BIOPHARMA INC	6,361,723	$31.62M	7.8%	$43.10	—	COM	929033108
—	PEAR THERAPEUTICS INC	18,631,771	$28.69M	7.1%	$6.20	—	CLASS A COM	704723105
—	RALLYBIO CORP	3,730,724	$28.17M	7.0%	$17.58	—	COM	75120L100
—	IMPEL NEUROPHARMA INC	2,884,791	$26.89M	6.7%	$8.85	—	COM	45258K109
—	AKOUOS INC	4,135,784	$19.4M	4.8%	$22.50	—	COM	00973J101
IDYA	IDEAYA BIOSCIENCES INC	1,398,066	$19.29M	4.8%	$7.13	+55.9%	COM	45166A102
—	SCPHARMACEUTICALS INC	3,561,474	$17.17M	4.2%	$5.92	—	COM	810648105
ARVN	ARVINAS INC	400,000	$16.84M	4.2%	$29.28	+71.4%	COM	04335A105
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$16.08M	4.0%	$19.04	+4.8%	COM	22663K107
PHVS	PHARVARIS N V	587,600	$12.99M	3.2%	$18.63	0.0%	COM	N69605108
COGT	COGENT BIOSCIENCES INC	1,129,200	$10.19M	2.5%	$6.91	-1.3%	COM	19240Q201
—	IVERIC BIO INC	1,027,874	$9.888M	2.4%	$16.46	—	COM	46583P102
—	HOMOLOGY MEDICINES INC	4,535,919	$8.936M	2.2%	$20.70	—	COM	438083107
RNAM	AVIDITY BIOSCIENCES INC	390,555	$5.675M	1.4%	$21.74	-31.5%	COM	05370A108
JANX	JANUX THERAPEUTICS INC	446,266	$5.449M	1.3%	$22.27	-46.8%	COM	47103J105
—	PROMETHEUS BIOSCIENCES INC	182,370	$5.148M	1.3%	$28.23	—	COM	74349U108
—	5 01 ACQUISITION CORP	365,126	$3.615M	0.9%	$10.17	—	COM CL A	33836P105
CABA	CABALETTA BIO INC	2,064,263	$2.188M	0.5%	$11.85	-88.1%	COM	12674W109
—	CIDARA THERAPEUTICS INC	1,134,511	$554K	0.1%	$3.84	—	COM	171757107