5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q3 2022 (← Previous) (Next →)

Filing Date: Nov 14, 2022

Total Value: $522M (100.0% shares, 0.0% debt)

Holdings (21)

— CINCOR PHARMA INC 31.0%

Value $162M Shares 4,937,646 Est. Cost $19.40 Unrealized —

TRDA ENTRADA THERAPEUTICS INC 13.3%

Value $69.48M Shares 4,408,379 Est. Cost $17.12 Unrealized —

— RALLYBIO CORP 10.3%

Value $53.98M Shares 3,730,724 Est. Cost $17.58 Unrealized —

— PEAR THERAPEUTICS INC 6.6%

Value $34.48M Shares 16,903,603 Est. Cost $6.20 Unrealized —

— AKOUOS INC 5.4%

Value $27.96M Shares 4,135,784 Est. Cost $22.50 Unrealized —

— VOR BIOPHARMA INC 4.9%

Value $25.32M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— SCPHARMACEUTICALS INC 4.2%

Value $21.74M Shares 3,334,852 Est. Cost $5.92 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 3.4%

Value $17.85M Shares 1,196,298 Est. Cost $7.13 Unrealized +82.1%

ARVN ARVINAS INC 3.4%

Value $17.8M Shares 400,000 Est. Cost $29.28 Unrealized +65.8%

CRNX CRINETICS PHARMACEUTICALS IN 3.2%

Value $16.93M Shares 862,286 Est. Cost $19.04 Unrealized +7.1%

— IMPEL NEUROPHARMA INC 2.7%

Value $14.05M Shares 2,884,791 Est. Cost $8.85 Unrealized —

COGT COGENT BIOSCIENCES INC 2.3%

Value $11.79M Shares 790,440 Est. Cost $6.91 Unrealized +98.3%

VRDN VIRIDIAN THERAPEUTICS INC 1.9%

Value $9.945M Shares 484,891 Est. Cost $17.98 Unrealized 0.0%

— IVERIC BIO INC 1.7%

Value $9.129M Shares 508,847 Est. Cost $16.46 Unrealized —

— HOMOLOGY MEDICINES INC 1.4%

Value $7.303M Shares 4,535,919 Est. Cost $20.70 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.2%

Value $6.378M Shares 390,555 Est. Cost $21.74 Unrealized -12.0%

JANX JANUX THERAPEUTICS INC 1.2%

Value $6.042M Shares 446,266 Est. Cost $22.27 Unrealized -40.0%

PHVS PHARVARIS N V 0.9%

Value $4.507M Shares 587,600 Est. Cost $18.63 Unrealized -16.3%

— 5 01 ACQUISITION CORP 0.7%

Value $3.651M Shares 365,126 Est. Cost $10.17 Unrealized —

— GEMINI THERAPEUTICS INC 0.2%

Value $860K Shares 524,500 Est. Cost $1.64 Unrealized —

— CIDARA THERAPEUTICS INC 0.1%

Value $712K Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CINCOR PHARMA INC	4,937,646	$162M	31.0%	$19.40	—	COM	17240Y109
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$69.48M	13.3%	$17.12	—	COM	29384C108
—	RALLYBIO CORP	3,730,724	$53.98M	10.3%	$17.58	—	COM	75120L100
—	PEAR THERAPEUTICS INC	16,903,603	$34.48M	6.6%	$6.20	—	CLASS A COM	704723105
—	AKOUOS INC	4,135,784	$27.96M	5.4%	$22.50	—	COM	00973J101
—	VOR BIOPHARMA INC	6,361,723	$25.32M	4.9%	$43.10	—	COM	929033108
—	SCPHARMACEUTICALS INC	3,334,852	$21.74M	4.2%	$5.92	—	COM	810648105
IDYA	IDEAYA BIOSCIENCES INC	1,196,298	$17.85M	3.4%	$7.13	+82.1%	COM	45166A102
ARVN	ARVINAS INC	400,000	$17.8M	3.4%	$29.28	+65.8%	COM	04335A105
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$16.93M	3.2%	$19.04	+7.1%	COM	22663K107
—	IMPEL NEUROPHARMA INC	2,884,791	$14.05M	2.7%	$8.85	—	COM	45258K109
COGT	COGENT BIOSCIENCES INC	790,440	$11.79M	2.3%	$6.91	+98.3%	COM	19240Q201
VRDN	VIRIDIAN THERAPEUTICS INC	484,891	$9.945M	1.9%	$17.98	0.0%	COM	92790C104
—	IVERIC BIO INC	508,847	$9.129M	1.7%	$16.46	—	COM	46583P102
—	HOMOLOGY MEDICINES INC	4,535,919	$7.303M	1.4%	$20.70	—	COM	438083107
RNAM	AVIDITY BIOSCIENCES INC	390,555	$6.378M	1.2%	$21.74	-12.0%	COM	05370A108
JANX	JANUX THERAPEUTICS INC	446,266	$6.042M	1.2%	$22.27	-40.0%	COM	47103J105
PHVS	PHARVARIS N V	587,600	$4.507M	0.9%	$18.63	-16.3%	COM	N69605108
—	5 01 ACQUISITION CORP	365,126	$3.651M	0.7%	$10.17	—	COM CL A	33836P105
—	GEMINI THERAPEUTICS INC	524,500	$860K	0.2%	$1.64	—	COM	36870G105
—	CIDARA THERAPEUTICS INC	1,134,511	$712K	0.1%	$3.84	—	COM	171757107