Avoro Capital Advisors LLC Diversified Active

Location: NEW YORK, NY

CIK: 0001633313 · Show all filings

Period: Q3 2024 (← Previous) (Next →)

Filing Date: Nov 14, 2024

Total Value ($000): $6,858,151 (100.0% shares, 0.0% debt)

Holdings (36)

UTHR UNITED THERAPEUTICS CORP 14.9%

Value ($000) $1,024,483 Shares 2,858,888 Est. Cost $134.94 Unrealized +150.3%

ASND ASCENDIS PHARMA 10.9%

Value ($000) $744,891 Shares 4,988,888 Est. Cost $126.96 Unrealized —

ARGX ARGENX SE 9.8%

Value ($000) $671,348 Shares 1,238,467 Est. Cost $186.36 Unrealized —

KRYS KRYSTAL BIOTECH INC 7.0%

Value ($000) $477,323 Shares 2,622,222 Est. Cost $86.03 Unrealized +124.1%

MDGL MADRIGAL PHARMACEUTICALS INC 6.3%

Value ($000) $430,594 Shares 2,029,000 Est. Cost $138.83 Unrealized +84.3%

APLS APELLIS PHARMACEUTICALS INC. 4.7%

Value ($000) $320,444 Shares 11,111,111 Est. Cost $48.71 Unrealized -24.0%

SRPT SAREPTA THERAPEUTICS INC 4.7%

Value ($000) $319,163 Shares 2,555,555 Est. Cost $106.42 Unrealized +29.9%

RNAM AVIDITY BIOSCIENCES INC 4.6%

Value ($000) $315,769 Shares 6,875,000 Est. Cost $20.57 Unrealized +111.0%

FOLD AMICUS THERAPEUTICS INC. 3.6%

Value ($000) $247,509 Shares 23,175,000 Est. Cost $10.47 Unrealized +4.0%

— INTRA-CELLULAR THERAPIES INC 3.3%

Value ($000) $223,169 Shares 3,050,000 Est. Cost $70.93 Unrealized —

XENE XENON PHARMACEUTICALS INC 3.3%

Value ($000) $223,097 Shares 5,666,666 Est. Cost $18.87 Unrealized +113.7%

KYMR KYMERA THERAPEUTICS INC 3.1%

Value ($000) $212,985 Shares 4,500,000 Est. Cost $33.55 Unrealized +31.6%

VERA VERA THERAPEUTICS INC 2.8%

Value ($000) $190,484 Shares 4,309,590 Est. Cost $35.64 Unrealized +6.5%

ARWR ARROWHEAD PHARMACEUTICALS INC. 2.5%

Value ($000) $172,178 Shares 8,888,888 Est. Cost $31.44 Unrealized -22.4%

BMRN BIOMARIN PHARMACEUTICAL INC 2.1%

Value ($000) $143,252 Shares 2,038,015 Est. Cost $85.96 Unrealized -2.8%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 2.0%

Value ($000) $139,668 Shares 2,770,100 Est. Cost $35.93 Unrealized +30.4%

PCVX VAXCYTE INC 2.0%

Value ($000) $134,267 Shares 1,175,000 Est. Cost $79.91 Unrealized +12.8%

SLNO SOLENO THERAPEUTICS INC 1.6%

Value ($000) $110,119 Shares 2,181,000 Est. Cost $38.69 Unrealized +23.7%

BCRX BIOCRYST PHARMACEUTICALS INC 1.3%

Value ($000) $90,174 Shares 11,865,000 Est. Cost $10.72 Unrealized -29.1%

SNDX SYNDAX PHARMACEUTICALS INC 1.1%

Value ($000) $74,852 Shares 3,888,437 Est. Cost $18.81 Unrealized +9.8%

OCUL OCULAR THERAPEUTIX INC 1.0%

Value ($000) $70,122 Shares 8,060,000 Est. Cost $6.99 Unrealized +17.9%

KURA KURA ONCOLOGY INC 1.0%

Value ($000) $69,201 Shares 3,541,505 Est. Cost $22.49 Unrealized -9.9%

— MERUS N V 1.0%

Value ($000) $67,696 Shares 1,355,000 Est. Cost $37.11 Unrealized —

— TOURMALINE BIO INC 0.8%

Value ($000) $57,133 Shares 2,222,222 Est. Cost $24.18 Unrealized —

MNKD MANNKIND CORP 0.8%

Value ($000) $55,038 Shares 8,750,000 Est. Cost $3.56 Unrealized +61.6%

RARE ULTRAGENYX PHARMACEUTICAL INC 0.7%

Value ($000) $46,107 Shares 830,000 Est. Cost $49.13 Unrealized +3.7%

AUTL AUTOLUS THERAPEUTICS PLC 0.7%

Value ($000) $44,815 Shares 12,345,678 Est. Cost $6.38 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.6%

Value ($000) $39,814 Shares 4,240,000 Est. Cost $14.36 Unrealized -34.0%

TSHA TAYSHA GENE THERAPIES INC 0.5%

Value ($000) $37,487 Shares 18,650,000 Est. Cost $2.04 Unrealized +7.7%

GLUE MONTE ROSA THERAPEUTICS INC 0.4%

Value ($000) $30,688 Shares 5,790,236 Est. Cost $14.44 Unrealized -65.1%

CGON CG ONCOLOGY INC 0.4%

Value ($000) $26,411 Shares 700,000 Est. Cost $40.84 Unrealized -14.2%

DYN DYNE THERAPEUTICS INC. 0.3%

Value ($000) $23,348 Shares 650,000 Est. Cost $37.89 Unrealized +5.0%

SYRE SPYRE THERAPEUTICS INC 0.3%

Value ($000) $17,605 Shares 598,600 Est. Cost $13.77 Unrealized +102.2%

WHWK AADI BIOSCIENCES INC 0.1%

Value ($000) $5,870 Shares 2,849,402 Est. Cost $24.27 Unrealized -93.3%

NGNE NEUROGENE INC 0.0%

Value ($000) $924 Shares 22,029 Est. Cost $35.27 Unrealized +10.0%

— INSMED INC 0.0%

Value ($000) $125 Shares 50,000 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
UTHR	UNITED THERAPEUTICS CORP	2,858,888	$1,024,483	14.9%	$134.94	+150.3%	Common	91307C102
ASND	ASCENDIS PHARMA	4,988,888	$744,891	10.9%	$126.96	—	Sponsored ADR	04351P101
ARGX	ARGENX SE	1,238,467	$671,348	9.8%	$186.36	—	Sponsored ADR	04016X101
KRYS	KRYSTAL BIOTECH INC	2,622,222	$477,323	7.0%	$86.03	+124.1%	Common	501147102
MDGL	MADRIGAL PHARMACEUTICALS INC	2,029,000	$430,594	6.3%	$138.83	+84.3%	Common	558868105
APLS	APELLIS PHARMACEUTICALS INC.	11,111,111	$320,444	4.7%	$48.71	-24.0%	Common	03753U106
SRPT	SAREPTA THERAPEUTICS INC	2,555,555	$319,163	4.7%	$106.42	+29.9%	Common	803607100
RNAM	AVIDITY BIOSCIENCES INC	6,875,000	$315,769	4.6%	$20.57	+111.0%	Common	05370A108
FOLD	AMICUS THERAPEUTICS INC.	23,175,000	$247,509	3.6%	$10.47	+4.0%	Common	03152W109
—	INTRA-CELLULAR THERAPIES INC	3,050,000	$223,169	3.3%	$70.93	—	Common	46116X101
XENE	XENON PHARMACEUTICALS INC	5,666,666	$223,097	3.3%	$18.87	+113.7%	Common	98420N105
KYMR	KYMERA THERAPEUTICS INC	4,500,000	$212,985	3.1%	$33.55	+31.6%	Common	501575104
VERA	VERA THERAPEUTICS INC	4,309,590	$190,484	2.8%	$35.64	+6.5%	Common	92337R101
ARWR	ARROWHEAD PHARMACEUTICALS INC.	8,888,888	$172,178	2.5%	$31.44	-22.4%	Common	04280A100
BMRN	BIOMARIN PHARMACEUTICAL INC	2,038,015	$143,252	2.1%	$85.96	-2.8%	Common	09061G101
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	2,770,100	$139,668	2.0%	$35.93	+30.4%	CLASS A ORD	61559X104
PCVX	VAXCYTE INC	1,175,000	$134,267	2.0%	$79.91	+12.8%	Common	92243G108
SLNO	SOLENO THERAPEUTICS INC	2,181,000	$110,119	1.6%	$38.69	+23.7%	Common	834203309
BCRX	BIOCRYST PHARMACEUTICALS INC	11,865,000	$90,174	1.3%	$10.72	-29.1%	Common	09058V103
SNDX	SYNDAX PHARMACEUTICALS INC	3,888,437	$74,852	1.1%	$18.81	+9.8%	Common	87164F105
OCUL	OCULAR THERAPEUTIX INC	8,060,000	$70,122	1.0%	$6.99	+17.9%	Common	67576A100
KURA	KURA ONCOLOGY INC	3,541,505	$69,201	1.0%	$22.49	-9.9%	Common	50127T109
—	MERUS N V	1,355,000	$67,696	1.0%	$37.11	—	Common	N5749R100
—	TOURMALINE BIO INC	2,222,222	$57,133	0.8%	$24.18	—	Common	89157D105
MNKD	MANNKIND CORP	8,750,000	$55,038	0.8%	$3.56	+61.6%	Common	56400P706
RARE	ULTRAGENYX PHARMACEUTICAL INC	830,000	$46,107	0.7%	$49.13	+3.7%	Common	90400D108
AUTL	AUTOLUS THERAPEUTICS PLC	12,345,678	$44,815	0.7%	$6.38	—	Sponsored ADR	05280R100
IOVA	IOVANCE BIOTHERAPEUTICS INC	4,240,000	$39,814	0.6%	$14.36	-34.0%	Common	462260100
TSHA	TAYSHA GENE THERAPIES INC	18,650,000	$37,487	0.5%	$2.04	+7.7%	Common	877619106
GLUE	MONTE ROSA THERAPEUTICS INC	5,790,236	$30,688	0.4%	$14.44	-65.1%	Common	61225M102
CGON	CG ONCOLOGY INC	700,000	$26,411	0.4%	$40.84	-14.2%	Common	156944100
DYN	DYNE THERAPEUTICS INC.	650,000	$23,348	0.3%	$37.89	+5.0%	Common	26818M108
SYRE	SPYRE THERAPEUTICS INC	598,600	$17,605	0.3%	$13.77	+102.2%	Common	00773J202
WHWK	AADI BIOSCIENCES INC	2,849,402	$5,870	0.1%	$24.27	-93.3%	Common	00032Q104
NGNE	NEUROGENE INC	22,029	$924	0.0%	$35.27	+10.0%	Common	64135M105
—	INSMED INC	50,000	$125	0.0%	—	—	Put	457669957