Avoro Capital Advisors LLC Diversified Active

Location: NEW YORK, NY

CIK: 0001633313 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value ($000): $5,710,278 (100.0% shares, 0.0% debt)

Holdings (30)

ASND ASCENDIS PHARMA 15.1%

Value ($000) $859,548 Shares 4,980,000 Est. Cost $127.83 Unrealized —

UTHR UNITED THERAPEUTICS CORP 11.9%

Value ($000) $681,020 Shares 2,370,000 Est. Cost $134.94 Unrealized +121.5%

ARGX ARGENX SE 11.3%

Value ($000) $647,684 Shares 1,175,000 Est. Cost $186.36 Unrealized —

MDGL MADRIGAL PHARMACEUTICALS INC 9.9%

Value ($000) $567,450 Shares 1,875,000 Est. Cost $138.83 Unrealized +114.6%

KRYS KRYSTAL BIOTECH INC 6.4%

Value ($000) $365,644 Shares 2,660,000 Est. Cost $89.11 Unrealized +64.8%

KYMR KYMERA THERAPEUTICS INC 5.0%

Value ($000) $286,084 Shares 6,555,555 Est. Cost $35.30 Unrealized -2.4%

APLS APELLIS PHARMACEUTICALS INC. 3.7%

Value ($000) $211,567 Shares 12,222,222 Est. Cost $47.01 Unrealized -60.6%

RNAM AVIDITY BIOSCIENCES INC 3.5%

Value ($000) $200,220 Shares 7,050,000 Est. Cost $22.48 Unrealized +32.6%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 3.4%

Value ($000) $195,880 Shares 4,150,000 Est. Cost $37.53 Unrealized +8.5%

— AKERO THERAPEUTICS INC 3.3%

Value ($000) $186,760 Shares 3,500,000 Est. Cost $53.36 Unrealized —

SLNO SOLENO THERAPEUTICS INC 3.0%

Value ($000) $171,749 Shares 2,050,000 Est. Cost $40.48 Unrealized +84.9%

XENE XENON PHARMACEUTICALS INC 3.0%

Value ($000) $169,020 Shares 5,400,000 Est. Cost $19.12 Unrealized +70.6%

ARWR ARROWHEAD PHARMACEUTICALS INC. 2.9%

Value ($000) $167,480 Shares 10,600,000 Est. Cost $29.27 Unrealized -51.0%

— MERUS N V 2.9%

Value ($000) $165,982 Shares 3,155,555 Est. Cost $40.46 Unrealized —

VERA VERA THERAPEUTICS INC 2.6%

Value ($000) $148,428 Shares 6,300,000 Est. Cost $36.12 Unrealized -37.7%

FOLD AMICUS THERAPEUTICS INC. 1.8%

Value ($000) $103,140 Shares 18,000,000 Est. Cost $10.47 Unrealized -38.3%

ALKS ALKERMES PLC 1.5%

Value ($000) $82,969 Shares 2,900,000 Est. Cost $28.91 Unrealized +3.0%

OCUL OCULAR THERAPEUTIX INC 1.2%

Value ($000) $68,672 Shares 7,400,000 Est. Cost $6.99 Unrealized +11.9%

— 89BIO INC 1.2%

Value ($000) $66,285 Shares 6,750,000 Est. Cost $7.76 Unrealized —

CNTA CENTESSA PHARMACEUTICALS PLC 1.2%

Value ($000) $65,700 Shares 5,000,000 Est. Cost $14.14 Unrealized —

QURE UNIQURE NV 0.9%

Value ($000) $50,533 Shares 3,625,000 Est. Cost $10.56 Unrealized +27.4%

TSHA TAYSHA GENE THERAPIES INC 0.9%

Value ($000) $50,127 Shares 21,700,000 Est. Cost $2.05 Unrealized +6.0%

— BLUEPRINT MEDICINES CORP 0.8%

Value ($000) $48,068 Shares 375,000 Est. Cost $88.11 Unrealized —

— TOURMALINE BIO INC 0.7%

Value ($000) $40,863 Shares 2,555,555 Est. Cost $23.05 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS INC 0.7%

Value ($000) $40,320 Shares 4,500,000 Est. Cost $10.72 Unrealized -13.1%

MNKD MANNKIND CORP 0.4%

Value ($000) $21,879 Shares 5,850,000 Est. Cost $3.56 Unrealized +23.9%

GLUE MONTE ROSA THERAPEUTICS INC 0.3%

Value ($000) $16,800 Shares 3,725,000 Est. Cost $13.91 Unrealized -67.9%

SEPN SEPTERNA INC 0.2%

Value ($000) $13,080 Shares 1,237,500 Est. Cost $21.57 Unrealized -61.8%

RARE ULTRAGENYX PHARMACEUTICAL INC 0.2%

Value ($000) $11,999 Shares 330,000 Est. Cost $49.13 Unrealized -26.6%

WHWK WHITEHAWK THERAPEUTICS INC 0.1%

Value ($000) $5,328 Shares 2,849,402 Est. Cost $24.27 Unrealized -92.8%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ASND	ASCENDIS PHARMA	4,980,000	$859,548	15.1%	$127.83	—	Sponsored ADR	04351P101
UTHR	UNITED THERAPEUTICS CORP	2,370,000	$681,020	11.9%	$134.94	+121.5%	Common	91307C102
ARGX	ARGENX SE	1,175,000	$647,684	11.3%	$186.36	—	Sponsored ADR	04016X101
MDGL	MADRIGAL PHARMACEUTICALS INC	1,875,000	$567,450	9.9%	$138.83	+114.6%	Common	558868105
KRYS	KRYSTAL BIOTECH INC	2,660,000	$365,644	6.4%	$89.11	+64.8%	Common	501147102
KYMR	KYMERA THERAPEUTICS INC	6,555,555	$286,084	5.0%	$35.30	-2.4%	Common	501575104
APLS	APELLIS PHARMACEUTICALS INC.	12,222,222	$211,567	3.7%	$47.01	-60.6%	Common	03753U106
RNAM	AVIDITY BIOSCIENCES INC	7,050,000	$200,220	3.5%	$22.48	+32.6%	Common	05370A108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	4,150,000	$195,880	3.4%	$37.53	+8.5%	CLASS A ORD	61559X104
—	AKERO THERAPEUTICS INC	3,500,000	$186,760	3.3%	$53.36	—	Common	00973Y108
SLNO	SOLENO THERAPEUTICS INC	2,050,000	$171,749	3.0%	$40.48	+84.9%	Common	834203309
XENE	XENON PHARMACEUTICALS INC	5,400,000	$169,020	3.0%	$19.12	+70.6%	Common	98420N105
ARWR	ARROWHEAD PHARMACEUTICALS INC.	10,600,000	$167,480	2.9%	$29.27	-51.0%	Common	04280A100
—	MERUS N V	3,155,555	$165,982	2.9%	$40.46	—	Common	N5749R100
VERA	VERA THERAPEUTICS INC	6,300,000	$148,428	2.6%	$36.12	-37.7%	Common	92337R101
FOLD	AMICUS THERAPEUTICS INC.	18,000,000	$103,140	1.8%	$10.47	-38.3%	Common	03152W109
ALKS	ALKERMES PLC	2,900,000	$82,969	1.5%	$28.91	+3.0%	Common	G01767105
OCUL	OCULAR THERAPEUTIX INC	7,400,000	$68,672	1.2%	$6.99	+11.9%	Common	67576A100
—	89BIO INC	6,750,000	$66,285	1.2%	$7.76	—	Common	282559103
CNTA	CENTESSA PHARMACEUTICALS PLC	5,000,000	$65,700	1.2%	$14.14	—	SPONSORED ADR	152309100
QURE	UNIQURE NV	3,625,000	$50,533	0.9%	$10.56	+27.4%	Common	N90064101
TSHA	TAYSHA GENE THERAPIES INC	21,700,000	$50,127	0.9%	$2.05	+6.0%	Common	877619106
—	BLUEPRINT MEDICINES CORP	375,000	$48,068	0.8%	$88.11	—	Common	09627Y109
—	TOURMALINE BIO INC	2,555,555	$40,863	0.7%	$23.05	—	Common	89157D105
BCRX	BIOCRYST PHARMACEUTICALS INC	4,500,000	$40,320	0.7%	$10.72	-13.1%	Common	09058V103
MNKD	MANNKIND CORP	5,850,000	$21,879	0.4%	$3.56	+23.9%	Common	56400P706
GLUE	MONTE ROSA THERAPEUTICS INC	3,725,000	$16,800	0.3%	$13.91	-67.9%	Common	61225M102
SEPN	SEPTERNA INC	1,237,500	$13,080	0.2%	$21.57	-61.8%	Common	81734D104
RARE	ULTRAGENYX PHARMACEUTICAL INC	330,000	$11,999	0.2%	$49.13	-26.6%	Common	90400D108
WHWK	WHITEHAWK THERAPEUTICS INC	2,849,402	$5,328	0.1%	$24.27	-92.8%	Common	00032Q104