Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q3 2013 (← Previous) (Next →)

Filing Date: Nov 20, 2013

Total Value: $954M (100.0% shares, 0.0% debt)

Holdings (34)

— ViroPharma Incorporated 12.7%

Value $121M Shares 3,093,291 Share Price $39.26 Est. Cost/Share $28.65 Unrealized @ Report Date —

— Cyberonics, Inc. 10.2%

Value $97.4M Shares 1,919,518 Share Price $50.74 Est. Cost/Share $51.92 Unrealized @ Report Date —

UTHR United Therapeutics Corp 8.8%

Value $83.85M Shares 1,063,442 Share Price $78.85 * Est. Cost/Share $65.75 Unrealized @ Report Date +11.2%

— Auxilium Pharmaceuticals, Inc. 8.7%

Value $83.06M Shares 4,563,520 Share Price $18.20 Est. Cost/Share $17.22 Unrealized @ Report Date —

— Cubist Pharmaceuticals, Inc. 6.8%

Value $64.48M Shares 1,014,611 Share Price $63.55 Est. Cost/Share $52.17 Unrealized @ Report Date —

— Intermune Inc. 5.8%

Value $55.3M Shares 3,595,756 Share Price $15.38 Est. Cost/Share $12.54 Unrealized @ Report Date —

— Abiomed Inc. 5.3%

Value $50.59M Shares 2,654,347 Share Price $19.06 Est. Cost/Share $21.24 Unrealized @ Report Date —

STAA STAAR Surgical Company 4.6%

Value $43.48M Shares 3,211,318 Share Price $13.54 * Est. Cost/Share $8.10 Unrealized @ Report Date +45.2%

— Onyx Pharmaceuticals, Inc. 4.5%

Value $42.83M Shares 343,473 Share Price $124.70 Est. Cost/Share $86.82 Unrealized @ Report Date —

BMRN Biomarin Pharmaceuticals, Inc 4.3%

Value $40.73M Shares 564,287 Share Price $72.17 * Est. Cost/Share $62.32 Unrealized @ Report Date +6.6%

— Questcor Pharmaceuticals, Inc. 4.0%

Value $38.05M Shares 655,997 Share Price $58.00 Est. Cost/Share $45.44 Unrealized @ Report Date —

— AMAG Pharmaceuticals, Inc. 3.9%

Value $36.84M Shares 1,715,377 Share Price $21.47 Est. Cost/Share $22.23 Unrealized @ Report Date —

VNDA Vanda Pharmaceutical Inc. 3.3%

Value $31.85M Shares 2,908,314 Share Price $10.95 * Est. Cost/Share $7.45 Unrealized @ Report Date +43.4%

— Rigel Pharmaceuticals Inc. 2.4%

Value $22.55M Shares 6,299,664 Share Price $3.58 Est. Cost/Share $3.43 Unrealized @ Report Date —

— Sequenom Inc. 2.3%

Value $21.9M Shares 8,202,254 Share Price $2.67 Est. Cost/Share $4.21 Unrealized @ Report Date —

— Anacor Pharmaceuticals, Inc. 1.8%

Value $16.99M Shares 1,600,178 Share Price $10.62 Est. Cost/Share $5.59 Unrealized @ Report Date —

— Momenta Pharmaceuticals, Inc. 1.7%

Value $16.36M Shares 1,136,676 Share Price $14.39 Est. Cost/Share $15.06 Unrealized @ Report Date —

— Kythera BioPharm 1.5%

Value $14.55M Shares 319,113 Share Price $45.59 Est. Cost/Share $40.58 Unrealized @ Report Date —

— Alimera Sciences, Inc. 1.4%

Value $13.67M Shares 3,634,984 Share Price $3.76 Est. Cost/Share $4.88 Unrealized @ Report Date —

FOLD Amicus Therapeutics, Inc. 1.1%

Value $10.72M Shares 4,622,230 Share Price $2.32 * Est. Cost/Share $3.07 Unrealized @ Report Date -18.4%

— QLT Inc. 1.0%

Value $9.503M Shares 2,052,411 Share Price $4.63 Est. Cost/Share $4.40 Unrealized @ Report Date —

EXAS Exact Sciences Corp 1.0%

Value $9.203M Shares 779,876 Share Price $11.80 * Est. Cost/Share $12.83 Unrealized @ Report Date 0.0%

— AVEO Pharmaceuticals, Inc. 0.8%

Value $7.229M Shares 3,509,205 Share Price $2.06 Est. Cost/Share $2.50 Unrealized @ Report Date —

— Savient Pharmaceuticals, Inc. 0.6%

Value $5.465M Shares 8,752,981 Share Price $0.62 Est. Cost/Share $0.56 Unrealized @ Report Date —

INSM Insmed, Inc. 0.4%

Value $4.157M Shares 266,299 Share Price $15.61 * Est. Cost/Share $10.22 Unrealized @ Report Date +24.3%

— Spectrum Pharmaceuticals Inc. 0.3%

Value $3.318M Shares 395,985 Share Price $8.38 Est. Cost/Share $7.46 Unrealized @ Report Date —

— Cytokinetics Inc. 0.2%

Value $1.98M Shares 261,544 Share Price $7.57 Est. Cost/Share $11.57 Unrealized @ Report Date —

— Xoma Ltd. 0.2%

Value $1.878M Shares 418,183 Share Price $4.49 Est. Cost/Share $3.63 Unrealized @ Report Date —

PRTA Prothena Corp PLC 0.2%

Value $1.79M Shares 88,500 Share Price $20.23 * Est. Cost/Share $9.30 Unrealized @ Report Date +90.2%

— Hyperion Therapeutics 0.2%

Value $1.638M Shares 62,700 Share Price $26.12 Est. Cost/Share $22.00 Unrealized @ Report Date —

— NxStage Medical, Inc. 0.1%

Value $581K Shares 44,129 Share Price $13.17 Est. Cost/Share $14.28 Unrealized @ Report Date —

— Celgene Corp. 0.0%

Value $260K Shares 1,690 Share Price $153.85 Est. Cost/Share $153.85 Unrealized @ Report Date —

— Sophiris Bio Inc 0.0%

Value $257K Shares 55,000 Share Price $4.67 Est. Cost/Share $4.67 Unrealized @ Report Date —

— Align Technology, Inc. 0.0%

Value $245K Shares 5,088 Share Price $48.15 Est. Cost/Share $48.15 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
—	ViroPharma Incorporated	3,093,291	$121M	12.7%	$39.26	$28.65	—	COM	928241108
—	Cyberonics, Inc.	1,919,518	$97.4M	10.2%	$50.74	$51.92	—	COM	23251P102
UTHR	United Therapeutics Corp	1,063,442	$83.85M	8.8%	$78.85 *	$65.75	+11.2%	COM	91307C102
—	Auxilium Pharmaceuticals, Inc.	4,563,520	$83.06M	8.7%	$18.20	$17.22	—	COM	05334D107
—	Cubist Pharmaceuticals, Inc.	1,014,611	$64.48M	6.8%	$63.55	$52.17	—	COM	229678107
—	Intermune Inc.	3,595,756	$55.3M	5.8%	$15.38	$12.54	—	COM	45884X103
—	Abiomed Inc.	2,654,347	$50.59M	5.3%	$19.06	$21.24	—	COM	003654100
STAA	STAAR Surgical Company	3,211,318	$43.48M	4.6%	$13.54 *	$8.10	+45.2%	COM	852312305
—	Onyx Pharmaceuticals, Inc.	343,473	$42.83M	4.5%	$124.70	$86.82	—	COM	683399109
BMRN	Biomarin Pharmaceuticals, Inc	564,287	$40.73M	4.3%	$72.17 *	$62.32	+6.6%	COM	09061G101
—	Questcor Pharmaceuticals, Inc.	655,997	$38.05M	4.0%	$58.00	$45.44	—	COM	74835Y101
—	AMAG Pharmaceuticals, Inc.	1,715,377	$36.84M	3.9%	$21.47	$22.23	—	COM	00163U106
VNDA	Vanda Pharmaceutical Inc.	2,908,314	$31.85M	3.3%	$10.95 *	$7.45	+43.4%	COM	921659108
—	Rigel Pharmaceuticals Inc.	6,299,664	$22.55M	2.4%	$3.58	$3.43	—	COM	766559603
—	Sequenom Inc.	8,202,254	$21.9M	2.3%	$2.67	$4.21	—	COM	817337405
—	Anacor Pharmaceuticals, Inc.	1,600,178	$16.99M	1.8%	$10.62	$5.59	—	COM	032420101
—	Momenta Pharmaceuticals, Inc.	1,136,676	$16.36M	1.7%	$14.39	$15.06	—	COM	60877T100
—	Kythera BioPharm	319,113	$14.55M	1.5%	$45.59	$40.58	—	COM	501570105
—	Alimera Sciences, Inc.	3,634,984	$13.67M	1.4%	$3.76	$4.88	—	COM	016259103
FOLD	Amicus Therapeutics, Inc.	4,622,230	$10.72M	1.1%	$2.32 *	$3.07	-18.4%	COM	03152W109
—	QLT Inc.	2,052,411	$9.503M	1.0%	$4.63	$4.40	—	COM	746927102
EXAS	Exact Sciences Corp	779,876	$9.203M	1.0%	$11.80 *	$12.83	0.0%	COM	30063P105
—	AVEO Pharmaceuticals, Inc.	3,509,205	$7.229M	0.8%	$2.06	$2.50	—	COM	053588109
—	Savient Pharmaceuticals, Inc.	8,752,981	$5.465M	0.6%	$0.62	$0.56	—	COM	80517Q100
INSM	Insmed, Inc.	266,299	$4.157M	0.4%	$15.61 *	$10.22	+24.3%	COM	457669307
—	Spectrum Pharmaceuticals Inc.	395,985	$3.318M	0.3%	$8.38	$7.46	—	COM	84763A108
—	Cytokinetics Inc.	261,544	$1.98M	0.2%	$7.57	$11.57	—	COM	23282W100
—	Xoma Ltd.	418,183	$1.878M	0.2%	$4.49	$3.63	—	COM	98419J107
PRTA	Prothena Corp PLC	88,500	$1.79M	0.2%	$20.23 *	$9.30	+90.2%	COM	G72800108
—	Hyperion Therapeutics	62,700	$1.638M	0.2%	$26.12	$22.00	—	COM	44915N101
—	NxStage Medical, Inc.	44,129	$581K	0.1%	$13.17	$14.28	—	COM	67072V103
—	Celgene Corp.	1,690	$260K	0.0%	$153.85	$153.85	—	COM	151020104
—	Sophiris Bio Inc	55,000	$257K	0.0%	$4.67	$4.67	—	COM	83578Q209
—	Align Technology, Inc.	5,088	$245K	0.0%	$48.15	$48.15	—	COM	162551014