Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q3 2013 (← Previous) (Next →)

Filing Date: Nov 20, 2013

Total Value: $954M (100.0% shares, 0.0% debt)

Holdings (34)

— ViroPharma Incorporated 12.7%

Value $121M Shares 3,093,291 Est. Cost $28.65 Unrealized —

— Cyberonics, Inc. 10.2%

Value $97.4M Shares 1,919,518 Est. Cost $51.92 Unrealized —

UTHR United Therapeutics Corp 8.8%

Value $83.85M Shares 1,063,442 Est. Cost $65.75 Unrealized +11.2%

— Auxilium Pharmaceuticals, Inc. 8.7%

Value $83.06M Shares 4,563,520 Est. Cost $17.22 Unrealized —

— Cubist Pharmaceuticals, Inc. 6.8%

Value $64.48M Shares 1,014,611 Est. Cost $52.17 Unrealized —

— Intermune Inc. 5.8%

Value $55.3M Shares 3,595,756 Est. Cost $12.54 Unrealized —

— Abiomed Inc. 5.3%

Value $50.59M Shares 2,654,347 Est. Cost $21.24 Unrealized —

STAA STAAR Surgical Company 4.6%

Value $43.48M Shares 3,211,318 Est. Cost $8.10 Unrealized +45.2%

— Onyx Pharmaceuticals, Inc. 4.5%

Value $42.83M Shares 343,473 Est. Cost $86.82 Unrealized —

BMRN Biomarin Pharmaceuticals, Inc 4.3%

Value $40.73M Shares 564,287 Est. Cost $62.32 Unrealized +6.6%

— Questcor Pharmaceuticals, Inc. 4.0%

Value $38.05M Shares 655,997 Est. Cost $45.44 Unrealized —

— AMAG Pharmaceuticals, Inc. 3.9%

Value $36.84M Shares 1,715,377 Est. Cost $22.23 Unrealized —

VNDA Vanda Pharmaceutical Inc. 3.3%

Value $31.85M Shares 2,908,314 Est. Cost $7.45 Unrealized +43.4%

— Rigel Pharmaceuticals Inc. 2.4%

Value $22.55M Shares 6,299,664 Est. Cost $3.43 Unrealized —

— Sequenom Inc. 2.3%

Value $21.9M Shares 8,202,254 Est. Cost $4.21 Unrealized —

— Anacor Pharmaceuticals, Inc. 1.8%

Value $16.99M Shares 1,600,178 Est. Cost $5.59 Unrealized —

— Momenta Pharmaceuticals, Inc. 1.7%

Value $16.36M Shares 1,136,676 Est. Cost $15.06 Unrealized —

— Kythera BioPharm 1.5%

Value $14.55M Shares 319,113 Est. Cost $40.58 Unrealized —

— Alimera Sciences, Inc. 1.4%

Value $13.67M Shares 3,634,984 Est. Cost $4.88 Unrealized —

FOLD Amicus Therapeutics, Inc. 1.1%

Value $10.72M Shares 4,622,230 Est. Cost $3.07 Unrealized -18.4%

— QLT Inc. 1.0%

Value $9.503M Shares 2,052,411 Est. Cost $4.40 Unrealized —

EXAS Exact Sciences Corp 1.0%

Value $9.203M Shares 779,876 Est. Cost $12.83 Unrealized 0.0%

— AVEO Pharmaceuticals, Inc. 0.8%

Value $7.229M Shares 3,509,205 Est. Cost $2.50 Unrealized —

— Savient Pharmaceuticals, Inc. 0.6%

Value $5.465M Shares 8,752,981 Est. Cost $0.56 Unrealized —

INSM Insmed, Inc. 0.4%

Value $4.157M Shares 266,299 Est. Cost $10.22 Unrealized +24.3%

— Spectrum Pharmaceuticals Inc. 0.3%

Value $3.318M Shares 395,985 Est. Cost $7.46 Unrealized —

— Cytokinetics Inc. 0.2%

Value $1.98M Shares 261,544 Est. Cost $11.57 Unrealized —

— Xoma Ltd. 0.2%

Value $1.878M Shares 418,183 Est. Cost $3.63 Unrealized —

PRTA Prothena Corp PLC 0.2%

Value $1.79M Shares 88,500 Est. Cost $9.30 Unrealized +90.2%

— Hyperion Therapeutics 0.2%

Value $1.638M Shares 62,700 Est. Cost $22.00 Unrealized —

— NxStage Medical, Inc. 0.1%

Value $581K Shares 44,129 Est. Cost $14.28 Unrealized —

— Celgene Corp. 0.0%

Value $260K Shares 1,690 Est. Cost $153.85 Unrealized —

— Sophiris Bio Inc 0.0%

Value $257K Shares 55,000 Est. Cost $4.67 Unrealized —

— Align Technology, Inc. 0.0%

Value $245K Shares 5,088 Est. Cost $48.15 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ViroPharma Incorporated	3,093,291	$121M	12.7%	$28.65	—	COM	928241108
—	Cyberonics, Inc.	1,919,518	$97.4M	10.2%	$51.92	—	COM	23251P102
UTHR	United Therapeutics Corp	1,063,442	$83.85M	8.8%	$65.75	+11.2%	COM	91307C102
—	Auxilium Pharmaceuticals, Inc.	4,563,520	$83.06M	8.7%	$17.22	—	COM	05334D107
—	Cubist Pharmaceuticals, Inc.	1,014,611	$64.48M	6.8%	$52.17	—	COM	229678107
—	Intermune Inc.	3,595,756	$55.3M	5.8%	$12.54	—	COM	45884X103
—	Abiomed Inc.	2,654,347	$50.59M	5.3%	$21.24	—	COM	003654100
STAA	STAAR Surgical Company	3,211,318	$43.48M	4.6%	$8.10	+45.2%	COM	852312305
—	Onyx Pharmaceuticals, Inc.	343,473	$42.83M	4.5%	$86.82	—	COM	683399109
BMRN	Biomarin Pharmaceuticals, Inc	564,287	$40.73M	4.3%	$62.32	+6.6%	COM	09061G101
—	Questcor Pharmaceuticals, Inc.	655,997	$38.05M	4.0%	$45.44	—	COM	74835Y101
—	AMAG Pharmaceuticals, Inc.	1,715,377	$36.84M	3.9%	$22.23	—	COM	00163U106
VNDA	Vanda Pharmaceutical Inc.	2,908,314	$31.85M	3.3%	$7.45	+43.4%	COM	921659108
—	Rigel Pharmaceuticals Inc.	6,299,664	$22.55M	2.4%	$3.43	—	COM	766559603
—	Sequenom Inc.	8,202,254	$21.9M	2.3%	$4.21	—	COM	817337405
—	Anacor Pharmaceuticals, Inc.	1,600,178	$16.99M	1.8%	$5.59	—	COM	032420101
—	Momenta Pharmaceuticals, Inc.	1,136,676	$16.36M	1.7%	$15.06	—	COM	60877T100
—	Kythera BioPharm	319,113	$14.55M	1.5%	$40.58	—	COM	501570105
—	Alimera Sciences, Inc.	3,634,984	$13.67M	1.4%	$4.88	—	COM	016259103
FOLD	Amicus Therapeutics, Inc.	4,622,230	$10.72M	1.1%	$3.07	-18.4%	COM	03152W109
—	QLT Inc.	2,052,411	$9.503M	1.0%	$4.40	—	COM	746927102
EXAS	Exact Sciences Corp	779,876	$9.203M	1.0%	$12.83	0.0%	COM	30063P105
—	AVEO Pharmaceuticals, Inc.	3,509,205	$7.229M	0.8%	$2.50	—	COM	053588109
—	Savient Pharmaceuticals, Inc.	8,752,981	$5.465M	0.6%	$0.56	—	COM	80517Q100
INSM	Insmed, Inc.	266,299	$4.157M	0.4%	$10.22	+24.3%	COM	457669307
—	Spectrum Pharmaceuticals Inc.	395,985	$3.318M	0.3%	$7.46	—	COM	84763A108
—	Cytokinetics Inc.	261,544	$1.98M	0.2%	$11.57	—	COM	23282W100
—	Xoma Ltd.	418,183	$1.878M	0.2%	$3.63	—	COM	98419J107
PRTA	Prothena Corp PLC	88,500	$1.79M	0.2%	$9.30	+90.2%	COM	G72800108
—	Hyperion Therapeutics	62,700	$1.638M	0.2%	$22.00	—	COM	44915N101
—	NxStage Medical, Inc.	44,129	$581K	0.1%	$14.28	—	COM	67072V103
—	Celgene Corp.	1,690	$260K	0.0%	$153.85	—	COM	151020104
—	Sophiris Bio Inc	55,000	$257K	0.0%	$4.67	—	COM	83578Q209
—	Align Technology, Inc.	5,088	$245K	0.0%	$48.15	—	COM	162551014