EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q1 2017 (← Previous) (Next →)

Filing Date: May 19, 2017

Total Value ($000): $395,567 (94.6% shares, 5.4% debt)

Holdings (33)

— ASSEMBLY BIOSCIENCES INC 19.0%

Value ($000) $75,021 Shares 2,943,164 Est. Cost $8.38 Unrealized —

IRWD IRONWOOD PHARMACEUTICALS INC 12.5%

Value ($000) $49,568 Shares 2,905,515 Est. Cost $9.45 Unrealized +44.6%

GLPG GALAPAGOS NV 12.0%

Value ($000) $47,494 Shares 551,041 Est. Cost $57.70 Unrealized —

— GILEAD SCIENCES INC 8.6%

Value ($000) $33,960 Shares 500,000 Est. Cost — Unrealized —

ASND ASCENDIS PHARMA A S 7.3%

Value ($000) $28,720 Shares 1,025,700 Est. Cost $20.59 Unrealized —

KURA KURA ONCOLOGY INC COM 5.8%

Value ($000) $22,985 Shares 2,611,906 Est. Cost $10.12 Unrealized -27.5%

— THERAVANCE BIOPHARMA INC 5.4%

Value ($000) $21,441 Shares 17,000,000 Est. Cost $1.14 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 5.1%

Value ($000) $20,072 Shares 673,100 Est. Cost $26.78 Unrealized +7.7%

CTMX CYTOMX THERAPEUTICS INC 3.5%

Value ($000) $13,729 Shares 794,969 Est. Cost $13.16 Unrealized 0.0%

— CASCADIAN THERAPEUTICS INC 3.1%

Value ($000) $12,420 Shares 3,000,000 Est. Cost $4.14 Unrealized —

FATE FATE THERAPEUTICS INC 2.9%

Value ($000) $11,543 Shares 2,537,026 Est. Cost $3.66 Unrealized 0.0%

— ATARA BIOTHERAPEUTICS INC 2.3%

Value ($000) $8,935 Shares 434,812 Est. Cost $17.40 Unrealized —

— ATYR PHARMA INC 2.0%

Value ($000) $8,024 Shares 2,292,659 Est. Cost $2.92 Unrealized —

— OVASCIENCE INC 1.7%

Value ($000) $6,568 Shares 3,512,332 Est. Cost $1.87 Unrealized —

— JOUNCE THERAPEUTICS INC 1.4%

Value ($000) $5,683 Shares 258,457 Est. Cost $21.99 Unrealized —

XNCR XENCOR INC 1.4%

Value ($000) $5,617 Shares 234,813 Est. Cost $24.05 Unrealized +0.2%

— KINDRED BIOSCIENCES INC 1.0%

Value ($000) $3,841 Shares 544,880 Est. Cost $7.10 Unrealized —

— NABRIVA THERAPEUTICS AG 0.8%

Value ($000) $3,177 Shares 264,773 Est. Cost $9.50 Unrealized —

— REGULUS THERAPEUTICS INC 0.6%

Value ($000) $2,492 Shares 1,510,000 Est. Cost $1.65 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 0.6%

Value ($000) $2,361 Shares 874,447 Est. Cost $4.11 Unrealized —

— VERSARTIS INC 0.5%

Value ($000) $2,135 Shares 100,000 Est. Cost $21.35 Unrealized —

— VIVEVE MED INC 0.4%

Value ($000) $1,583 Shares 250,000 Est. Cost $6.33 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 0.3%

Value ($000) $1,361 Shares 23,300 Est. Cost $43.55 Unrealized +10.1%

— DICERNA PHARMACEUTICALS INC 0.3%

Value ($000) $1,299 Shares 382,000 Est. Cost $3.40 Unrealized —

— FIBROGEN INC 0.3%

Value ($000) $1,036 Shares 42,009 Est. Cost $24.72 Unrealized —

— SYROS PHARMACEUTICALS INC 0.3%

Value ($000) $1,013 Shares 63,596 Est. Cost $13.87 Unrealized —

BMY BRISTOL MYERS SQUIBB CO 0.2%

Value ($000) $928 Shares 17,060 Est. Cost $39.73 Unrealized +0.5%

— CHEMOCENTRYX INC 0.2%

Value ($000) $859 Shares 118,000 Est. Cost $7.28 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC COM 0.1%

Value ($000) $484 Shares 35,301 Est. Cost $12.54 Unrealized -17.2%

— CASCADIAN THERAPEUTICS INC 0.1%

Value ($000) $430 Shares 103,800 Est. Cost — Unrealized —

— OREXIGEN THERAPEUTICS INC 0.1%

Value ($000) $405 Shares 117,726 Est. Cost $3.44 Unrealized —

WVE WAVE LIFE SCIENCES LTD 0.1%

Value ($000) $275 Shares 10,000 Est. Cost $27.93 Unrealized 0.0%

— FORWARD PHARMA A/S 0.0%

Value ($000) $108 Shares 5,025 Est. Cost $21.49 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$75,021	19.0%	$8.38	—	COM	045396108
IRWD	IRONWOOD PHARMACEUTICALS INC	2,905,515	$49,568	12.5%	$9.45	+44.6%	COM	46333X108
GLPG	GALAPAGOS NV	551,041	$47,494	12.0%	$57.70	—	SPONSORED ADR	36315X101
—	GILEAD SCIENCES INC	500,000	$33,960	8.6%	—	—	Call	375558903
ASND	ASCENDIS PHARMA A S	1,025,700	$28,720	7.3%	$20.59	—	SPONSORED ADR	04351P101
KURA	KURA ONCOLOGY INC COM	2,611,906	$22,985	5.8%	$10.12	-27.5%	COM	50127T109
—	THERAVANCE BIOPHARMA INC	17,000,000	$21,441	5.4%	$1.14	—	NOTE	88339KAA0
ACRS	ACLARIS THERAPEUTICS INC	673,100	$20,072	5.1%	$26.78	+7.7%	COM	00461U105
CTMX	CYTOMX THERAPEUTICS INC	794,969	$13,729	3.5%	$13.16	0.0%	COM	23284F105
—	CASCADIAN THERAPEUTICS INC	3,000,000	$12,420	3.1%	$4.14	—	COM	14740B606
FATE	FATE THERAPEUTICS INC	2,537,026	$11,543	2.9%	$3.66	0.0%	COM	31189P102
—	ATARA BIOTHERAPEUTICS INC	434,812	$8,935	2.3%	$17.40	—	COM	046513107
—	ATYR PHARMA INC	2,292,659	$8,024	2.0%	$2.92	—	COM	002120103
—	OVASCIENCE INC	3,512,332	$6,568	1.7%	$1.87	—	COM	69014Q101
—	JOUNCE THERAPEUTICS INC	258,457	$5,683	1.4%	$21.99	—	COM	481116101
XNCR	XENCOR INC	234,813	$5,617	1.4%	$24.05	+0.2%	COM	98401F105
—	KINDRED BIOSCIENCES INC	544,880	$3,841	1.0%	$7.10	—	COM	494577109
—	NABRIVA THERAPEUTICS AG	264,773	$3,177	0.8%	$9.50	—	SPONSORED ADR	62957M104
—	REGULUS THERAPEUTICS INC	1,510,000	$2,492	0.6%	$1.65	—	COM	75915K101
—	ADVERUM BIOTECHNOLOGIES INC	874,447	$2,361	0.6%	$4.11	—	COM	00773U108
—	VERSARTIS INC	100,000	$2,135	0.5%	$21.35	—	COM	92529L102
—	VIVEVE MED INC	250,000	$1,583	0.4%	$6.33	—	COM	92852W204
AGIO	AGIOS PHARMACEUTICALS INC	23,300	$1,361	0.3%	$43.55	+10.1%	COM	00847X104
—	DICERNA PHARMACEUTICALS INC	382,000	$1,299	0.3%	$3.40	—	COM	253031108
—	FIBROGEN INC	42,009	$1,036	0.3%	$24.72	—	COM	31572Q808
—	SYROS PHARMACEUTICALS INC	63,596	$1,013	0.3%	$13.87	—	COM	87184Q107
BMY	BRISTOL MYERS SQUIBB CO	17,060	$928	0.2%	$39.73	+0.5%	COM	110122108
—	CHEMOCENTRYX INC	118,000	$859	0.2%	$7.28	—	COM	16383L106
SNDX	SYNDAX PHARMACEUTICALS INC COM	35,301	$484	0.1%	$12.54	-17.2%	COM	87164F105
—	CASCADIAN THERAPEUTICS INC	103,800	$430	0.1%	—	—	Call	14740B906
—	OREXIGEN THERAPEUTICS INC	117,726	$405	0.1%	$3.44	—	COM	686164302
WVE	WAVE LIFE SCIENCES LTD	10,000	$275	0.1%	$27.93	0.0%	SHS	Y95308105
—	FORWARD PHARMA A/S	5,025	$108	0.0%	$21.49	—	SPONSORED ADR	34986J105