EcoR1 Capital, LLC Quant / Systematic

Location: San Francisco, CA

CIK: 0001587114 · Show all filings

Period: Q2 2017 (← Previous) (Next →)

Filing Date: Aug 14, 2017

Total Value: $563M (100.0% shares, 0.0% debt)

Holdings (36)

— ALEXION PHARMACEUTICALS, INC 13.9%

Value $78.22M Shares 569,500 Est. Cost — Unrealized —

IRWD IRONWOOD PHARMACEUTICALS INC 12.6%

Value $70.87M Shares 3,753,635 Est. Cost $10.60 Unrealized +37.1%

— ASSEMBLY BIOSCIENCES INC 10.8%

Value $60.78M Shares 2,943,164 Est. Cost $8.38 Unrealized —

— FIBROGEN INC 9.1%

Value $51.21M Shares 1,585,457 Est. Cost $32.10 Unrealized —

GLPG GALAPAGOS NV SPON ADR 7.9%

Value $44.27M Shares 578,505 Est. Cost $58.59 Unrealized —

ASND ASCENDIS PHARMA A S 7.3%

Value $41.16M Shares 1,482,600 Est. Cost $22.80 Unrealized —

— GILEAD SCIENCES INC 6.8%

Value $38.05M Shares 500,000 Est. Cost — Unrealized —

SGMO SANGAMO BIOSCIENCES INC 4.0%

Value $22.6M Shares 2,568,119 Est. Cost $6.42 Unrealized 0.0%

KURA KURA ONCOLOGY INC COM 3.4%

Value $18.91M Shares 2,033,622 Est. Cost $10.12 Unrealized -10.1%

— TOCAGEN INC 3.2%

Value $18.07M Shares 1,502,373 Est. Cost $12.03 Unrealized —

CTMX CYTOMX THERAPEUTICS INC 2.2%

Value $12.32M Shares 794,969 Est. Cost $13.16 Unrealized +14.5%

EDIT EDITAS MEDICINE INC COM 2.1%

Value $12.03M Shares 717,107 Est. Cost $18.02 Unrealized 0.0%

— CASCADIAN THERAPEUTICS INC 2.0%

Value $11.14M Shares 3,000,000 Est. Cost $4.14 Unrealized —

CRVS CORVUS PHARMACEUTICALS INC 1.7%

Value $9.741M Shares 805,000 Est. Cost $10.68 Unrealized 0.0%

— VERTEX PHARMACEUTICALS INC 1.6%

Value $9.109M Shares 60,000 Est. Cost — Unrealized —

FATE FATE THERAPEUTICS INC 1.5%

Value $8.22M Shares 2,537,026 Est. Cost $3.66 Unrealized +4.7%

— ATYR PHARMA INC 1.4%

Value $7.795M Shares 2,292,659 Est. Cost $2.92 Unrealized —

— OVASCIENCE INC 1.0%

Value $5.479M Shares 3,512,332 Est. Cost $1.87 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 0.9%

Value $5.03M Shares 185,472 Est. Cost $26.78 Unrealized +1.5%

— KINDRED BIOSCIENCES INC 0.8%

Value $4.686M Shares 544,880 Est. Cost $7.10 Unrealized —

— TETRAPHASE PHARMACEUTICALS INC 0.8%

Value $4.516M Shares 633,400 Est. Cost $7.13 Unrealized —

— EDITAS MEDICINE INC COM 0.8%

Value $4.315M Shares 255,000 Est. Cost — Unrealized —

— REGULUS THERAPEUTICS INC 0.6%

Value $3.656M Shares 3,709,144 Est. Cost $1.26 Unrealized —

— ACHILLION PHARMACEUTICALS INC 0.6%

Value $3.41M Shares 742,835 Est. Cost $4.59 Unrealized —

— NABRIVA THERAPEUTICS 0.5%

Value $2.775M Shares 264,773 Est. Cost $10.48 Unrealized —

— DICERNA PHARMACEUTICALS INC 0.4%

Value $2.435M Shares 767,992 Est. Cost $3.28 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 0.4%

Value $2.186M Shares 874,447 Est. Cost $4.11 Unrealized —

— MINERVA NEUROSCIENCES INC 0.4%

Value $1.981M Shares 223,802 Est. Cost $8.85 Unrealized —

— BIOHAVEN PHARMACEUTICAL HLDG CO LTD 0.3%

Value $1.75M Shares 70,000 Est. Cost $25.00 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 0.2%

Value $1.199M Shares 23,300 Est. Cost $43.55 Unrealized +17.4%

— CHEMOCENTRYX INC 0.2%

Value $1.104M Shares 118,000 Est. Cost $7.28 Unrealized —

BMY BRISTOL MYERS SQUIBB CO 0.2%

Value $951K Shares 17,060 Est. Cost $39.73 Unrealized +0.4%

— CLOVIS ONCOLOGY INC 0.2%

Value $936K Shares 10,000 Est. Cost $93.60 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 0.1%

Value $831K Shares 10,425 Est. Cost $63.91 Unrealized 0.0%

— SEATTLE GENETICS INC 0.1%

Value $776K Shares 15,000 Est. Cost $51.73 Unrealized —

— ARATANA THERAPEUTICS INC 0.1%

Value $723K Shares 100,000 Est. Cost $7.23 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ALEXION PHARMACEUTICALS, INC	569,500	$78.22M	13.9%	—	—	Call	015351909
IRWD	IRONWOOD PHARMACEUTICALS INC	3,753,635	$70.87M	12.6%	$10.60	+37.1%	COM	46333X108
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$60.78M	10.8%	$8.38	—	COM	045396108
—	FIBROGEN INC	1,585,457	$51.21M	9.1%	$32.10	—	COM	31572Q808
GLPG	GALAPAGOS NV SPON ADR	578,505	$44.27M	7.9%	$58.59	—	SPONSORED ADR	36315X101
ASND	ASCENDIS PHARMA A S	1,482,600	$41.16M	7.3%	$22.80	—	SPONSORED ADR	04351P101
—	GILEAD SCIENCES INC	500,000	$38.05M	6.8%	—	—	Call	375558903
SGMO	SANGAMO BIOSCIENCES INC	2,568,119	$22.6M	4.0%	$6.42	0.0%	COM	800677106
KURA	KURA ONCOLOGY INC COM	2,033,622	$18.91M	3.4%	$10.12	-10.1%	COM	50127T109
—	TOCAGEN INC	1,502,373	$18.07M	3.2%	$12.03	—	COM	888846102
CTMX	CYTOMX THERAPEUTICS INC	794,969	$12.32M	2.2%	$13.16	+14.5%	COM	23284F105
EDIT	EDITAS MEDICINE INC COM	717,107	$12.03M	2.1%	$18.02	0.0%	COM	28106W103
—	CASCADIAN THERAPEUTICS INC	3,000,000	$11.14M	2.0%	$4.14	—	COM	14740B606
CRVS	CORVUS PHARMACEUTICALS INC	805,000	$9.741M	1.7%	$10.68	0.0%	COM	221015100
—	VERTEX PHARMACEUTICALS INC	60,000	$9.109M	1.6%	—	—	Call	92532F900
FATE	FATE THERAPEUTICS INC	2,537,026	$8.22M	1.5%	$3.66	+4.7%	COM	31189P102
—	ATYR PHARMA INC	2,292,659	$7.795M	1.4%	$2.92	—	COM	002120103
—	OVASCIENCE INC	3,512,332	$5.479M	1.0%	$1.87	—	COM	69014Q101
ACRS	ACLARIS THERAPEUTICS INC	185,472	$5.03M	0.9%	$26.78	+1.5%	COM	00461U105
—	KINDRED BIOSCIENCES INC	544,880	$4.686M	0.8%	$7.10	—	COM	494577109
—	TETRAPHASE PHARMACEUTICALS INC	633,400	$4.516M	0.8%	$7.13	—	COM	88165N105
—	EDITAS MEDICINE INC COM	255,000	$4.315M	0.8%	—	—	Call	28106W903
—	REGULUS THERAPEUTICS INC	3,709,144	$3.656M	0.6%	$1.26	—	COM	75915K101
—	ACHILLION PHARMACEUTICALS INC	742,835	$3.41M	0.6%	$4.59	—	COM	00448Q201
—	NABRIVA THERAPEUTICS	264,773	$2.775M	0.5%	$10.48	—	COM	G63637105
—	DICERNA PHARMACEUTICALS INC	767,992	$2.435M	0.4%	$3.28	—	COM	253031108
—	ADVERUM BIOTECHNOLOGIES INC	874,447	$2.186M	0.4%	$4.11	—	COM	00773U108
—	MINERVA NEUROSCIENCES INC	223,802	$1.981M	0.4%	$8.85	—	COM	603380106
—	BIOHAVEN PHARMACEUTICAL HLDG CO LTD	70,000	$1.75M	0.3%	$25.00	—	COM	G11196105
AGIO	AGIOS PHARMACEUTICALS INC	23,300	$1.199M	0.2%	$43.55	+17.4%	COM	00847X104
—	CHEMOCENTRYX INC	118,000	$1.104M	0.2%	$7.28	—	COM	16383L106
BMY	BRISTOL MYERS SQUIBB CO	17,060	$951K	0.2%	$39.73	+0.4%	COM	110122108
—	CLOVIS ONCOLOGY INC	10,000	$936K	0.2%	$93.60	—	COM	189464100
ALNY	ALNYLAM PHARMACEUTICALS INC	10,425	$831K	0.1%	$63.91	0.0%	COM	02043Q107
—	SEATTLE GENETICS INC	15,000	$776K	0.1%	$51.73	—	COM	812578102
—	ARATANA THERAPEUTICS INC	100,000	$723K	0.1%	$7.23	—	COM	03874P101