RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q3 2014 (← Previous) (Next →)

Filing Date: Nov 14, 2014

Total Value: $846M (100.0% shares, 0.0% debt)

Holdings (46)

ACAD ACADIA PHARMACEUTICALS INC 15.4%

Value $130M Shares 5,250,000 Est. Cost $23.39 Unrealized 0.0%

— DYAX CORP 9.3%

Value $79.03M Shares 7,809,139 Est. Cost $8.24 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 8.2%

Value $69.14M Shares 7,069,159 Est. Cost $9.01 Unrealized +36.1%

— ACHILLION PHARMACEUTICALS INC 7.9%

Value $66.87M Shares 6,700,000 Est. Cost $4.78 Unrealized —

SGMO SANGAMO BIOSCIENCES INC 7.6%

Value $64.71M Shares 6,000,000 Est. Cost $9.24 Unrealized +41.3%

— AVANIR PHARMACEUTICALS INC 7.6%

Value $64.21M Shares 5,386,700 Est. Cost $11.92 Unrealized —

— SUNESIS PHARMACEUTICALS INC 4.1%

Value $34.77M Shares 4,869,261 Est. Cost $5.18 Unrealized —

— DICERNA PHARMACEUTICALS INC 3.7%

Value $30.92M Shares 2,428,571 Est. Cost $28.25 Unrealized —

— ACHILLION PHARMACEUTICALS IN 3.5%

Value $29.94M Shares 3,000,000 Est. Cost $4.78 Unrealized —

— BLUEBIRD BIO INC 3.1%

Value $26.15M Shares 728,812 Est. Cost $30.29 Unrealized —

— OPHTHOTECH CORP 2.7%

Value $22.93M Shares 588,941 Est. Cost $33.27 Unrealized —

— ZS PHARMA INC 2.6%

Value $22.14M Shares 564,483 Est. Cost $39.23 Unrealized —

TGTX TG THERAPEUTICS INC 2.6%

Value $22.04M Shares 2,065,571 Est. Cost $9.27 Unrealized 0.0%

— NOVAVAX INC 2.5%

Value $21.13M Shares 5,067,083 Est. Cost $2.24 Unrealized —

— DYNAVAX TECHNOLOGIES CORP 2.1%

Value $17.42M Shares 12,179,002 Est. Cost $1.67 Unrealized —

— VERSARTIS INC 2.0%

Value $17.07M Shares 898,993 Est. Cost $41.65 Unrealized —

— THERAPEUTICSMD INC 1.9%

Value $16.03M Shares 3,454,332 Est. Cost $3.00 Unrealized —

— ZAFGEN INC 1.7%

Value $14.4M Shares 732,960 Est. Cost $19.65 Unrealized —

AKBA AKEBIA THERAPEUTICS INC 1.6%

Value $13.22M Shares 597,363 Est. Cost $24.08 Unrealized -4.6%

SGMO SANGAMO BIOSCIENCES INC 1.6%

Value $13.16M Shares 1,220,209 Est. Cost $9.24 Unrealized +41.3%

XNCR XENCOR INC 1.4%

Value $11.63M Shares 1,248,923 Est. Cost $8.86 Unrealized +14.1%

ENTA ENANTA PHARMACEUTICALS INC 1.2%

Value $9.893M Shares 250,000 Est. Cost $36.32 Unrealized +9.7%

— TENAX THERAPEUTICS INC 1.1%

Value $9.182M Shares 2,336,375 Est. Cost $3.93 Unrealized —

— SCYNEXIS INC 0.7%

Value $6.208M Shares 840,000 Est. Cost $8.02 Unrealized —

— VICAL INC 0.7%

Value $6.132M Shares 5,475,419 Est. Cost $1.12 Unrealized —

— AURIS MED HLDG AG 0.6%

Value $5.424M Shares 940,000 Est. Cost $5.77 Unrealized —

— T2 BIOSYSTEMS INC 0.3%

Value $2.496M Shares 138,002 Est. Cost $18.09 Unrealized —

— WAFERGEN BIO-SYSTEMS INC 0.3%

Value $2.436M Shares 560,000 Est. Cost $4.35 Unrealized —

— OCERA THERAPEUTICS INC 0.2%

Value $2.046M Shares 417,476 Est. Cost $11.51 Unrealized —

— ALIMERA SCIENCES INC 0.2%

Value $1.321M Shares 243,726 Est. Cost $7.89 Unrealized —

CDXS CODEXIS INC 0.1%

Value $1.175M Shares 504,279 Est. Cost $2.15 Unrealized 0.0%

PTCT PTC THERAPEUTICS INC 0.1%

Value $1.135M Shares 25,800 Est. Cost $31.28 Unrealized 0.0%

AGIO AGIOS PHARMACEUTICALS INC 0.1%

Value $1.08M Shares 17,600 Est. Cost $43.10 Unrealized 0.0%

VRTX VERTEX PHARMACEUTICALS INC 0.1%

Value $1.044M Shares 9,300 Est. Cost $95.21 Unrealized 0.0%

— MERRIMACK PHARMACEUTICALS INC 0.1%

Value $1.022M Shares 116,400 Est. Cost $8.78 Unrealized —

RGEN REPLIGEN CORP 0.1%

Value $896K Shares 45,000 Est. Cost $21.05 Unrealized 0.0%

REGN REGENERON PHARMACEUTICALS 0.1%

Value $883K Shares 2,450 Est. Cost $333.32 Unrealized 0.0%

BIIB BIOGEN IDEC INC 0.1%

Value $860K Shares 2,600 Est. Cost $329.72 Unrealized 0.0%

AMGN AMGEN INC 0.1%

Value $829K Shares 5,900 Est. Cost $94.52 Unrealized 0.0%

— CELGENE CORP 0.1%

Value $825K Shares 8,700 Est. Cost $94.83 Unrealized —

ALKS ALKERMES PLC 0.1%

Value $823K Shares 19,200 Est. Cost $44.82 Unrealized 0.0%

— KERYX BIOPHARMACEUTICALS INC 0.1%

Value $814K Shares 59,200 Est. Cost $13.75 Unrealized —

— KYTHERA BIOPHARMACEUTICALS 0.1%

Value $745K Shares 22,750 Est. Cost $32.75 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 0.1%

Value $743K Shares 30,000 Est. Cost $23.39 Unrealized 0.0%

PBYI PUMA BIOTECHNOLOGY INC 0.1%

Value $740K Shares 3,100 Est. Cost $205.34 Unrealized 0.0%

— NEWLINK GENETICS CORP 0.1%

Value $643K Shares 30,000 Est. Cost $21.43 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ACAD	ACADIA PHARMACEUTICALS INC	5,250,000	$130M	15.4%	$23.39	0.0%	Call	004225108
—	DYAX CORP	7,809,139	$79.03M	9.3%	$8.24	—	COM	26746E103
BCRX	BIOCRYST PHARMACEUTICALS	7,069,159	$69.14M	8.2%	$9.01	+36.1%	COM	09058V103
—	ACHILLION PHARMACEUTICALS INC	6,700,000	$66.87M	7.9%	$4.78	—	COM	00448Q201
SGMO	SANGAMO BIOSCIENCES INC	6,000,000	$64.71M	7.6%	$9.24	+41.3%	Call	800677106
—	AVANIR PHARMACEUTICALS INC	5,386,700	$64.21M	7.6%	$11.92	—	CL A NEW	05348P401
—	SUNESIS PHARMACEUTICALS INC	4,869,261	$34.77M	4.1%	$5.18	—	COM NEW	867328601
—	DICERNA PHARMACEUTICALS INC	2,428,571	$30.92M	3.7%	$28.25	—	COM	253031108
—	ACHILLION PHARMACEUTICALS IN	3,000,000	$29.94M	3.5%	$4.78	—	Call	00448Q201
—	BLUEBIRD BIO INC	728,812	$26.15M	3.1%	$30.29	—	COM	09609G100
—	OPHTHOTECH CORP	588,941	$22.93M	2.7%	$33.27	—	COM	683745103
—	ZS PHARMA INC	564,483	$22.14M	2.6%	$39.23	—	COM	98979G105
TGTX	TG THERAPEUTICS INC	2,065,571	$22.04M	2.6%	$9.27	0.0%	COM	88322Q108
—	NOVAVAX INC	5,067,083	$21.13M	2.5%	$2.24	—	COM	670002104
—	DYNAVAX TECHNOLOGIES CORP	12,179,002	$17.42M	2.1%	$1.67	—	COM	268158102
—	VERSARTIS INC	898,993	$17.07M	2.0%	$41.65	—	COM	92529L102
—	THERAPEUTICSMD INC	3,454,332	$16.03M	1.9%	$3.00	—	COM	88338N107
—	ZAFGEN INC	732,960	$14.4M	1.7%	$19.65	—	COM	98885E103
AKBA	AKEBIA THERAPEUTICS INC	597,363	$13.22M	1.6%	$24.08	-4.6%	COM	00972D105
SGMO	SANGAMO BIOSCIENCES INC	1,220,209	$13.16M	1.6%	$9.24	+41.3%	COM	800677106
XNCR	XENCOR INC	1,248,923	$11.63M	1.4%	$8.86	+14.1%	COM	98401F105
ENTA	ENANTA PHARMACEUTICALS INC	250,000	$9.893M	1.2%	$36.32	+9.7%	COM	29251M106
—	TENAX THERAPEUTICS INC	2,336,375	$9.182M	1.1%	$3.93	—	COM	88032L100
—	SCYNEXIS INC	840,000	$6.208M	0.7%	$8.02	—	COM	811292101
—	VICAL INC	5,475,419	$6.132M	0.7%	$1.12	—	COM	925602104
—	AURIS MED HLDG AG	940,000	$5.424M	0.6%	$5.77	—	COM	H03579101
—	T2 BIOSYSTEMS INC	138,002	$2.496M	0.3%	$18.09	—	COM	89853L104
—	WAFERGEN BIO-SYSTEMS INC	560,000	$2.436M	0.3%	$4.35	—	COM PAR$	93041P308
—	OCERA THERAPEUTICS INC	417,476	$2.046M	0.2%	$11.51	—	COM	67552A108
—	ALIMERA SCIENCES INC	243,726	$1.321M	0.2%	$7.89	—	COM	016259103
CDXS	CODEXIS INC	504,279	$1.175M	0.1%	$2.15	0.0%	COM	192005106
PTCT	PTC THERAPEUTICS INC	25,800	$1.135M	0.1%	$31.28	0.0%	COM	69366J200
AGIO	AGIOS PHARMACEUTICALS INC	17,600	$1.08M	0.1%	$43.10	0.0%	COM	00847X104
VRTX	VERTEX PHARMACEUTICALS INC	9,300	$1.044M	0.1%	$95.21	0.0%	COM	92532F100
—	MERRIMACK PHARMACEUTICALS INC	116,400	$1.022M	0.1%	$8.78	—	COM	590328100
RGEN	REPLIGEN CORP	45,000	$896K	0.1%	$21.05	0.0%	COM	759916109
REGN	REGENERON PHARMACEUTICALS	2,450	$883K	0.1%	$333.32	0.0%	COM	75886F107
BIIB	BIOGEN IDEC INC	2,600	$860K	0.1%	$329.72	0.0%	COM	09062X103
AMGN	AMGEN INC	5,900	$829K	0.1%	$94.52	0.0%	COM	031162100
—	CELGENE CORP	8,700	$825K	0.1%	$94.83	—	COM	151020104
ALKS	ALKERMES PLC	19,200	$823K	0.1%	$44.82	0.0%	SHS	G01767105
—	KERYX BIOPHARMACEUTICALS INC	59,200	$814K	0.1%	$13.75	—	COM	492515101
—	KYTHERA BIOPHARMACEUTICALS	22,750	$745K	0.1%	$32.75	—	COM	501570105
ACAD	ACADIA PHARMACEUTICALS INC	30,000	$743K	0.1%	$23.39	0.0%	COM	004225108
PBYI	PUMA BIOTECHNOLOGY INC	3,100	$740K	0.1%	$205.34	0.0%	COM	74587V107
—	NEWLINK GENETICS CORP	30,000	$643K	0.1%	$21.43	—	COM	651511107