RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q1 2018 (← Previous) (Next →)

Filing Date: May 15, 2018

Total Value: $1.305B (100.0% shares, 0.0% debt)

Holdings (31)

WVE WAVE LIFE SCIENCES LTD 23.1%

Value $301M Shares 7,512,049 Est. Cost $16.44 Unrealized +155.7%

ASND ASCENDIS PHARMA A S 21.2%

Value $277M Shares 4,240,536 Est. Cost $17.96 Unrealized —

— AVEXIS INC 9.7%

Value $127M Shares 1,028,289 Est. Cost $31.86 Unrealized —

— MYOVANT SCIENCES LTD 4.6%

Value $60.2M Shares 2,830,455 Est. Cost $12.11 Unrealized —

— SAGE THERAPEUTICS INC 4.4%

Value $56.88M Shares 353,133 Est. Cost $164.71 Unrealized —

IFRX INFLARX NV 3.6%

Value $46.74M Shares 1,620,653 Est. Cost $17.97 Unrealized +46.7%

— ZOGENIX INC 3.5%

Value $45.87M Shares 1,145,268 Est. Cost $16.89 Unrealized —

— DICERNA PHARMACEUTICALS INC 2.9%

Value $37.6M Shares 3,933,489 Est. Cost $18.43 Unrealized —

— SCPHARMACEUTICALS INC 2.7%

Value $35.43M Shares 2,857,143 Est. Cost $12.09 Unrealized —

— ENDOCYTE INC 2.7%

Value $35.28M Shares 3,881,793 Est. Cost $4.92 Unrealized —

TGTX TG THERAPEUTICS INC 2.7%

Value $35.11M Shares 2,472,344 Est. Cost $12.78 Unrealized 0.0%

— KALA PHARMACEUTICALS INC 2.6%

Value $33.45M Shares 2,113,236 Est. Cost $22.84 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 2.6%

Value $33.32M Shares 6,984,692 Est. Cost $7.39 Unrealized -30.5%

— RA PHARMACEUTICALS INC 1.6%

Value $20.45M Shares 3,851,808 Est. Cost $8.78 Unrealized —

— SOLID BIOSCIENCES INC 1.5%

Value $20.17M Shares 2,689,444 Est. Cost $7.50 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 1.5%

Value $19.9M Shares 900,000 Est. Cost $14.72 Unrealized +33.5%

— CLEARSIDE BIOMEDICAL INC 1.3%

Value $16.36M Shares 1,525,000 Est. Cost $10.73 Unrealized —

— AVEO PHARMACEUTICALS INC 1.1%

Value $14.68M Shares 5,062,759 Est. Cost $2.59 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 1.0%

Value $13.66M Shares 1,441,070 Est. Cost $9.16 Unrealized +14.3%

— CATALYST BIOSCIENCES INC 1.0%

Value $13.29M Shares 514,917 Est. Cost $25.80 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 0.9%

Value $11.14M Shares 659,059 Est. Cost $15.14 Unrealized 0.0%

SPRO SPERO THERAPEUTICS INC 0.8%

Value $10.57M Shares 741,647 Est. Cost $12.27 Unrealized -1.2%

— BIOHAVEN PHARMACTL HLDG CO LTD 0.7%

Value $9.367M Shares 363,636 Est. Cost $25.00 Unrealized —

VKTX VIKING THERAPEUTICS INC 0.7%

Value $8.868M Shares 2,029,396 Est. Cost $5.53 Unrealized 0.0%

— SUNESIS PHARMACEUTICALS INC 0.5%

Value $6.722M Shares 2,471,456 Est. Cost $3.69 Unrealized —

KRYS KRYSTAL BIOTECH INC 0.4%

Value $5.005M Shares 496,071 Est. Cost $10.08 Unrealized -2.2%

— GLYCOMIMETICS INC 0.3%

Value $4.115M Shares 253,547 Est. Cost $16.23 Unrealized —

— PROTEON THERAPEUTICS INC 0.3%

Value $3.344M Shares 1,337,462 Est. Cost $1.53 Unrealized —

— G1 THERAPEUTICS INC 0.1%

Value $1.482M Shares 40,000 Est. Cost $17.44 Unrealized —

— EDGE THERAPEUTICS INC 0.0%

Value $337K Shares 285,491 Est. Cost $1.18 Unrealized —

— CTI BIOPHARMA CORP 0.0%

Value $222K Shares 56,951 Est. Cost $3.90 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,512,049	$301M	23.1%	$16.44	+155.7%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	4,240,536	$277M	21.2%	$17.96	—	SPONSORED ADR	04351P101
—	AVEXIS INC	1,028,289	$127M	9.7%	$31.86	—	COM	05366U100
—	MYOVANT SCIENCES LTD	2,830,455	$60.2M	4.6%	$12.11	—	COM	G637AM102
—	SAGE THERAPEUTICS INC	353,133	$56.88M	4.4%	$164.71	—	COM	78667J108
IFRX	INFLARX NV	1,620,653	$46.74M	3.6%	$17.97	+46.7%	COM	N44821101
—	ZOGENIX INC	1,145,268	$45.87M	3.5%	$16.89	—	COM NEW	98978L204
—	DICERNA PHARMACEUTICALS INC	3,933,489	$37.6M	2.9%	$18.43	—	COM	253031108
—	SCPHARMACEUTICALS INC	2,857,143	$35.43M	2.7%	$12.09	—	COM	810648105
—	ENDOCYTE INC	3,881,793	$35.28M	2.7%	$4.92	—	COM	29269A102
TGTX	TG THERAPEUTICS INC	2,472,344	$35.11M	2.7%	$12.78	0.0%	COM	88322Q108
—	KALA PHARMACEUTICALS INC	2,113,236	$33.45M	2.6%	$22.84	—	COM	483119103
BCRX	BIOCRYST PHARMACEUTICALS	6,984,692	$33.32M	2.6%	$7.39	-30.5%	COM	09058V103
—	RA PHARMACEUTICALS INC	3,851,808	$20.45M	1.6%	$8.78	—	COM	74933V108
—	SOLID BIOSCIENCES INC	2,689,444	$20.17M	1.5%	$7.50	—	COM	83422E105
APLS	APELLIS PHARMACEUTICALS INC	900,000	$19.9M	1.5%	$14.72	+33.5%	COM	03753U106
—	CLEARSIDE BIOMEDICAL INC	1,525,000	$16.36M	1.3%	$10.73	—	COM	185063104
—	AVEO PHARMACEUTICALS INC	5,062,759	$14.68M	1.1%	$2.59	—	COM	053588109
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$13.66M	1.0%	$9.16	+14.3%	COM	483497103
—	CATALYST BIOSCIENCES INC	514,917	$13.29M	1.0%	$25.80	—	COM NEW	14888D208
IOVA	IOVANCE BIOTHERAPEUTICS INC	659,059	$11.14M	0.9%	$15.14	0.0%	COM	462260100
SPRO	SPERO THERAPEUTICS INC	741,647	$10.57M	0.8%	$12.27	-1.2%	COM	84833T103
—	BIOHAVEN PHARMACTL HLDG CO LTD	363,636	$9.367M	0.7%	$25.00	—	COM	G11196105
VKTX	VIKING THERAPEUTICS INC	2,029,396	$8.868M	0.7%	$5.53	0.0%	COM	92686J106
—	SUNESIS PHARMACEUTICALS INC	2,471,456	$6.722M	0.5%	$3.69	—	COM PAR	867328700
KRYS	KRYSTAL BIOTECH INC	496,071	$5.005M	0.4%	$10.08	-2.2%	COM	501147102
—	GLYCOMIMETICS INC	253,547	$4.115M	0.3%	$16.23	—	COM	38000Q102
—	PROTEON THERAPEUTICS INC	1,337,462	$3.344M	0.3%	$1.53	—	COM	74371L109
—	G1 THERAPEUTICS INC	40,000	$1.482M	0.1%	$17.44	—	COM	3621LQ109
—	EDGE THERAPEUTICS INC	285,491	$337K	0.0%	$1.18	—	COM	279870109
—	CTI BIOPHARMA CORP	56,951	$222K	0.0%	$3.90	—	COM NEW	12648L601