Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q2 2018 (← Previous) (Next →)
Filing Date: Nov 15, 2018
Total Value: $906M
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| ASND | Ascendis Pharma A/S | 2,479,514 | $165M | 18.2% | $66.52 | $65.40 | — | American Depositary Shares | 04351P101 |
| — | Nucana Biomed | 4,000,000 | $76M | 8.4% | $19.00 | $19.00 | — | Ordinary Shares | GB00BYWYV |
| — | ObsEva SA | 4,749,623 | $71.91M | 7.9% | $15.14 | $13.49 | — | Common Shares | H5861P103 |
| NTRA | Natera | 3,100,560 | $58.35M | 6.4% | $18.82 * | $9.81 | +24.0% | Common Shares | 632307104 |
| — | Merus N.V. | 1,961,039 | $44.63M | 4.9% | $22.76 | $18.53 | — | Common Shares | N5749R100 |
| CHRS | Coherus BioSciences (frmly Intekrin) | 2,893,221 | $40.51M | 4.5% | $14.00 * | $10.94 | +30.8% | Common Shares | 19249H103 |
| — | Spark Therapeutics | 481,270 | $39.83M | 4.4% | $82.76 | $66.59 | — | Common Shares | 84652J103 |
| — | Audentes Therapeutics | 933,640 | $35.67M | 3.9% | $38.21 | $30.05 | — | Common Shares | 05070R104 |
| ACRS | Aclaris Therapeutics | 1,539,480 | $30.74M | 3.4% | $19.97 * | $21.19 | -12.8% | Common Shares | 00461U105 |
| — | Iterum Therapeutics | 1,726,514 | $18.8M | 2.1% | $10.89 | $10.89 | — | Common Shares | G6333L101 |
| — | Allergan plc ⚠ | 111,550 | $18.6M | 2.1% | $166.72 | $167.97 | — | — | G0177J108 |
| — | Alexion Pharmaceuticals Inc ⚠ | 140,752 | $17.47M | 1.9% | $124.15 | $116.15 | — | — | 015351109 |
| — | Kiniksa Pharmaceuticals, Ltd | 922,700 | $16.01M | 1.8% | $17.35 | $17.35 | — | Common Stock Class A | G5269C101 |
| — | Celgene Corp ⚠ | 184,399 | $14.64M | 1.6% | $79.42 | $79.42 | — | — | 151020104 |
| APLS | Apellis Pharmaceuticals, Inc | 615,802 | $13.55M | 1.5% | $22.00 * | $19.65 | +16.9% | Common Shares | 03753U106 |
| — | Nucana Biomed | 666,666 | $12.67M | 1.4% | $19.00 | $18.92 | — | American Depositary Shares | 67022C106 |
| — | Amarin | 3,886,718 | $12.01M | 1.3% | $3.09 | $3.09 | — | Series A Preferred Stock | 023111PR2 |
| CRSP | CRISPR Therapeutics AG ⚠ | 200,000 | $11.75M | 1.3% | $58.76 | — | — | PUT | H17182108 |
| AZN | AstraZeneca PLC ⚠ | 329,800 | $11.58M | 1.3% | $35.11 | $35.01 | — | — | 046353108 |
| — | Amarin | 3,321,588 | $10.26M | 1.1% | $3.09 | $3.01 | — | American Depositary Shares | 023111206 |
| — | Aimmune Therapeutics Inc ⚠ | 375,044 | $10.09M | 1.1% | $26.89 | $29.48 | — | — | 00900T107 |
| HRTX | Heron Therapeutics Inc ⚠ | 258,585 | $10.05M | 1.1% | $38.85 * | $22.68 | +40.3% | — | 427746102 |
| — | Intercept Pharmaceuticals Inc ⚠ | 106,817 | $8.963M | 1.0% | $83.91 | $83.87 | — | — | 45845P108 |
| — | GW Pharmaceuticals PLC ⚠ | 63,070 | $8.801M | 1.0% | $139.54 | $124.56 | — | — | 36197T103 |
| — | bluebird bio Inc ⚠ | 55,371 | $8.691M | 1.0% | $156.96 | $157.00 | — | — | 09609G100 |
| — | Adamas Pharmaceuticals Inc ⚠ | 283,398 | $7.321M | 0.8% | $25.83 | $24.75 | — | — | 00548A106 |
| — | Rigel Pharmaceuticals Inc ⚠ | 2,272,727 | $6.433M | 0.7% | $2.83 | $3.15 | — | — | 766559603 |
| SRPT | Sarepta Therapeutics Inc ⚠ | 48,400 | $6.398M | 0.7% | $132.19 * | $94.31 | 0.0% | — | 803607100 |
| — | Kadmon Holdings Inc ⚠ | 1,769,583 | $6.056M | 0.7% | $3.42 | $4.16 | — | — | 48283N106 |
| ESPR | Esperion Therapeutics Inc ⚠ | 151,161 | $5.924M | 0.7% | $39.19 * | $50.52 | 0.0% | — | 29664W105 |
| — | Blueprint Medicines Corp ⚠ | 92,200 | $5.853M | 0.6% | $63.48 | $63.48 | — | — | 09627Y109 |
| — | Synlogic Inc. (fmrly Mirna) | 574,972 | $5.652M | 0.6% | $9.83 | $9.38 | — | Common Shares | 87166L100 |
| — | Histogenics | 2,077,040 | $5.193M | 0.6% | $2.50 | $2.75 | — | Common Shares | 43358V109 |
| — | Clearside Biomedical Inc ⚠ | 432,904 | $4.628M | 0.5% | $10.69 | $10.73 | — | — | 185063104 |
| CPRX | Catalyst Pharmaceuticals Inc ⚠ | 1,449,957 | $4.524M | 0.5% | $3.12 * | $3.30 | -8.1% | — | 14888U101 |
| RYTM | Rhythm Pharmaceuticals Inc ⚠ | 140,300 | $4.386M | 0.5% | $31.26 * | $27.34 | 0.0% | — | 76243J105 |
| PTCT | PTC Therapeutics Inc ⚠ | 127,079 | $4.287M | 0.5% | $33.73 * | $25.34 | +23.1% | — | 69366J200 |
| — | Kala Pharmaceuticals Inc ⚠ | 303,376 | $4.166M | 0.5% | $13.73 | $15.06 | — | — | 483119103 |
| — | Otonomy Inc ⚠ | 979,978 | $3.774M | 0.4% | $3.85 | $4.19 | — | — | 68906L105 |
| — | Conatus Pharmaceuticals Inc ⚠ | 858,850 | $3.676M | 0.4% | $4.28 | $4.28 | — | — | 20600T108 |
| PBYI | Puma Biotechnology Inc ⚠ | 61,936 | $3.664M | 0.4% | $59.16 * | $57.95 | 0.0% | — | 74587V107 |
| — | Spectrum Pharmaceuticals Inc ⚠ | 169,965 | $3.563M | 0.4% | $20.96 | $20.99 | — | — | 84763A108 |
| — | Foamix Pharmaceuticals Ltd ⚠ | 682,399 | $3.419M | 0.4% | $5.01 | $5.12 | — | — | M46135105 |
| — | Dermira Inc ⚠ | 364,340 | $3.352M | 0.4% | $9.20 | $7.99 | — | — | 24983L104 |
| — | Reata Pharmaceuticals Inc ⚠ | 89,909 | $3.144M | 0.3% | $34.97 | $20.52 | — | — | 75615P103 |
| KURA | Kura Oncology Inc ⚠ | 167,900 | $3.056M | 0.3% | $18.20 * | $16.94 | 0.0% | — | 50127T109 |
| — | Edge Therapeutics | 2,852,711 | $2.938M | 0.3% | $1.03 | $1.18 | — | Common Shares | 279870109 |
| SVRA | Savara Inc ⚠ | 256,692 | $2.905M | 0.3% | $11.32 * | $10.03 | 0.0% | — | 805111101 |
| — | AMAG Pharmaceuticals Inc ⚠ | 142,511 | $2.78M | 0.3% | $19.51 | $19.53 | — | — | 00163U106 |
| — | Chiasma | 1,767,102 | $2.445M | 0.3% | $1.38 | $1.49 | — | Common Shares | 16706W102 |
| — | ALLERGAN PLC ⚠ | 11,490 | $1.916M | 0.2% | $166.75 | $167.97 | — | Common Shares | G0177J108 |
| — | ALEXION PHARMACEUTICALS INC ⚠ | 14,498 | $1.8M | 0.2% | $124.16 | $116.15 | — | Common Shares | 015351109 |
| — | Aduro Biotech Inc ⚠ | 241,318 | $1.689M | 0.2% | $7.00 | $8.53 | — | — | 00739L101 |
| — | CELGENE CORP ⚠ | 19,014 | $1.51M | 0.2% | $79.42 | $79.42 | — | Common Shares | 151020104 |
| — | Calithera Biosciences Inc ⚠ | 297,223 | $1.486M | 0.2% | $5.00 | $5.86 | — | — | 13089P101 |
| CRSP | CRISPR THERAPEUTICS AG ⚠ | 20,600 | $1.21M | 0.1% | $58.74 | — | — | PUT | H17182108 |
| AZN | ASTRAZENECA PLC-SPONS ADR ⚠ | 33,981 | $1.193M | 0.1% | $35.11 | $35.01 | — | American Depositary Shares | 046353108 |
| — | KADMON HOLDINGS LLC ⚠ | 288,021 | $1.15M | 0.1% | $3.99 | $4.16 | — | Common Shares | 48283N106 |
| — | AIMMUNE THERAPEUTICS INC ⚠ | 38,528 | $1.036M | 0.1% | $26.89 | $29.48 | — | Common Shares | 00900T107 |
| HRTX | HERON THERAPEUTICS INC ⚠ | 26,644 | $1.035M | 0.1% | $38.85 * | $22.68 | +40.3% | Common Shares | 427746102 |
| — | INTERCEPT PHARMACEUTICALS IN ⚠ | 11,005 | $923K | 0.1% | $83.87 | $83.87 | — | Common Shares | 45845P108 |
| — | OncoMed Pharmaceuticals Inc ⚠ | 396,244 | $915K | 0.1% | $2.31 | $3.15 | — | — | 68234X102 |
| — | GW PHARMACEUTICALS -ADR ⚠ | 6,497 | $907K | 0.1% | $139.60 | $124.56 | — | American Depositary Shares | 36197T103 |
| — | ChemoCentryx Inc | 68,258 | $899K | 0.1% | $13.17 | $13.17 | — | COMM | 16383L106 |
| — | BLUEBIRD BIO INC ⚠ | 5,707 | $896K | 0.1% | $157.00 | $157.00 | — | Common Shares | 09609G100 |
| — | ADAMAS PHARMACEUTICALS INC ⚠ | 29,192 | $754K | 0.1% | $25.83 | $24.75 | — | Common Shares | 00548A106 |
| SNDX | Syndax Pharmaceuticals Inc ⚠ | 98,613 | $693K | 0.1% | $7.03 * | $10.60 | -7.4% | — | 87164F105 |
| — | RIGEL PHARMACEUTICALS INC ⚠ | 234,107 | $663K | 0.1% | $2.83 | $3.15 | — | Common Shares | 766559603 |
| SRPT | SAREPTA THERAPEUTICS INC ⚠ | 4,986 | $659K | 0.1% | $132.17 * | $94.31 | 0.0% | Common Shares | 803607100 |
| ESPR | ESPERION THERAPEUTICS INC ⚠ | 15,571 | $610K | 0.1% | $39.18 * | $50.52 | 0.0% | Common Shares | 29664W105 |
| IPHYF | Innate Pharma SA | 110,788 | $604K | 0.1% | $5.45 * | $7.12 | 0.0% | COMM | F5277D100 |
| — | BLUEPRINT MEDICINES CORP ⚠ | 9,499 | $603K | 0.1% | $63.48 | $63.48 | — | Common Shares | 09627Y109 |
| CPRX | CATALYST PHARMACEUTICAL PART ⚠ | 161,089 | $503K | 0.1% | $3.12 * | $3.30 | -8.1% | Common Shares | 14888U101 |
| — | CLEARSIDE BIOMEDICAL INC ⚠ | 44,620 | $477K | 0.1% | $10.69 | $10.73 | — | Common Shares | 185063104 |
| RYTM | RHYTHM PHARMACEUTICALS INC ⚠ | 14,452 | $452K | 0.0% | $31.28 * | $27.34 | 0.0% | Common Shares | 76243J105 |
| — | KALA PHARMACEUTICALS INC ⚠ | 32,248 | $443K | 0.0% | $13.74 | $15.06 | — | Common Shares | 483119103 |
| PTCT | PTC THERAPEUTICS INC ⚠ | 13,104 | $442K | 0.0% | $33.73 * | $25.34 | +23.1% | Common Shares | 69366J200 |
| — | OTONOMY INC ⚠ | 99,874 | $385K | 0.0% | $3.85 | $4.19 | — | Common Shares | 68906L105 |
| — | CONATUS PHARMACEUTICALS INC ⚠ | 88,742 | $380K | 0.0% | $4.28 | $4.28 | — | Common Shares | 20600T108 |
| — | Forty Seven Inc | 23,700 | $379K | 0.0% | $15.99 | $15.99 | — | COMM | 34983P104 |
| PBYI | PUMA BIOTECHNOLOGY INC ⚠ | 6,384 | $378K | 0.0% | $59.21 * | $57.95 | 0.0% | Common Shares | 74587V107 |
| — | SPECTRUM PHARMACEUTICALS INC ⚠ | 17,488 | $367K | 0.0% | $20.99 | $20.99 | — | Common Shares | 84763A108 |
| — | FOAMIX PHARMACEUTICALS LTD ⚠ | 72,017 | $361K | 0.0% | $5.01 | $5.12 | — | Common Shares | M46135105 |
| — | DERMIRA INC ⚠ | 37,543 | $345K | 0.0% | $9.19 | $7.99 | — | Common Shares | 24983L104 |
| — | REATA PHARMACEUTICALS INC-A ⚠ | 9,307 | $325K | 0.0% | $34.92 | $20.52 | — | Common Shares | 75615P103 |
| KURA | KURA ONCOLOGY INC ⚠ | 17,295 | $315K | 0.0% | $18.21 * | $16.94 | 0.0% | Common Shares | 50127T109 |
| SVRA | SAVARA INC ⚠ | 26,441 | $299K | 0.0% | $11.31 * | $10.03 | 0.0% | Common Shares | 805111101 |
| — | AMAG PHARMACEUTICALS INC ⚠ | 14,695 | $287K | 0.0% | $19.53 | $19.53 | — | Common Shares | 00163U106 |
| — | ADURO BIOTECH INC ⚠ | 24,857 | $174K | 0.0% | $7.00 | $8.53 | — | Common Shares | 00739L101 |
| — | ONCOMED PHARMACEUTICALS INC ⚠ | 68,899 | $159K | 0.0% | $2.31 | $3.15 | — | Common Shares | 68234X102 |
| — | CALITHERA BIOSCIENCES INC ⚠ | 30,622 | $153K | 0.0% | $5.00 | $5.86 | — | Common Shares | 13089P101 |
| SNDX | SYNDAX PHARMACEUTICALS INC ⚠ | 12,354 | $87,000 | 0.0% | $7.04 * | $10.60 | -7.4% | Common Shares | 87164F105 |
| — | Auris Medical Holding AG (frmlyAuris Medical) | 140,000 | $0 | 0.0% | $0.00 | $1.60 | — | Warrant(s) | H0381L104 |