RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q2 2019 (← Previous) (Next →)

Filing Date: Aug 14, 2019

Total Value: $1.863B (100.0% shares, 0.0% debt)

Holdings (25)

ASND ASCENDIS PHARMA A S 25.5%

Value $476M Shares 4,132,442 Share Price $115.15 Est. Cost/Share $17.96 Unrealized @ Report Date —

WVE WAVE LIFE SCIENCES LTD 10.9%

Value $203M Shares 7,775,207 Share Price $26.09 * Est. Cost/Share $17.26 Unrealized @ Report Date +62.5%

— ZOGENIX INC 9.5%

Value $178M Shares 3,722,504 Share Price $47.78 Est. Cost/Share $37.11 Unrealized @ Report Date —

— RA PHARMACEUTICALS INC 7.4%

Value $137M Shares 4,858,260 Share Price $28.19 Est. Cost/Share $8.41 Unrealized @ Report Date —

— SYNTHORX INC 7.1%

Value $131M Shares 9,724,598 Share Price $13.51 Est. Cost/Share $17.38 Unrealized @ Report Date —

— EIDOS THERAPEUTICS INC 6.1%

Value $113M Shares 2,162,671 Share Price $52.12 Est. Cost/Share $20.34 Unrealized @ Report Date —

— ORCHARD THERAPEUTICS PLC 3.8%

Value $71.47M Shares 5,108,330 Share Price $13.99 Est. Cost/Share $15.84 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 3.2%

Value $59.52M Shares 6,880,323 Share Price $8.65 * Est. Cost/Share $12.35 Unrealized @ Report Date -38.8%

— MYOVANT SCIENCES LTD 3.2%

Value $59.24M Shares 6,545,642 Share Price $9.05 Est. Cost/Share $12.18 Unrealized @ Report Date —

CRNX CRINETICS PHARMACEUTICALS INC 2.5%

Value $46.88M Shares 1,875,209 Share Price $25.00 Est. Cost/Share $29.55 Unrealized @ Report Date -16.2%

RYTM RHYTHM PHARMACEUTICALS INC 2.2%

Value $41.47M Shares 1,884,782 Share Price $22.00 * Est. Cost/Share $28.23 Unrealized @ Report Date -10.6%

— DICERNA PHARMACEUTICALS INC 2.1%

Value $38.69M Shares 2,456,669 Share Price $15.75 Est. Cost/Share $18.43 Unrealized @ Report Date —

ARVN ARVINAS INC 2.0%

Value $37.13M Shares 1,688,412 Share Price $21.99 * Est. Cost/Share $16.46 Unrealized @ Report Date +27.7%

— PREVAIL THERAPEUTICS INC 1.9%

Value $36.22M Shares 2,743,625 Share Price $13.20 Est. Cost/Share $13.20 Unrealized @ Report Date —

AXSM AXSOME THERAPEUTICS INC 1.9%

Value $34.53M Shares 1,340,828 Share Price $25.75 * Est. Cost/Share $9.29 Unrealized @ Report Date +115.9%

STOK STOKE THERAPEUTICS INC 1.8%

Value $32.67M Shares 1,119,963 Share Price $29.17 * Est. Cost/Share $26.85 Unrealized @ Report Date 0.0%

— KALA PHARMACEUTICALS INC 1.6%

Value $28.95M Shares 4,537,478 Share Price $6.38 Est. Cost/Share $13.25 Unrealized @ Report Date —

— SHOCKWAVE MED INC 1.5%

Value $28.29M Shares 495,608 Share Price $57.09 Est. Cost/Share $33.47 Unrealized @ Report Date —

— PRECISION BIOSCIENCES INC 1.3%

Value $24.41M Shares 1,842,366 Share Price $13.25 Est. Cost/Share $17.95 Unrealized @ Report Date —

— SOLID BIOSCIENCES INC 1.1%

Value $21.29M Shares 2,689,444 Share Price $7.92 Est. Cost/Share $7.50 Unrealized @ Report Date —

ALEC ALECTOR INC 1.0%

Value $19M Shares 1,000,000 Share Price $19.00 * Est. Cost/Share $18.92 Unrealized @ Report Date +7.3%

— G1 THERAPEUTICS INC 0.8%

Value $14.84M Shares 483,990 Share Price $30.66 Est. Cost/Share $20.11 Unrealized @ Report Date —

— X4 PHARMACEUTICALS INC 0.7%

Value $12.92M Shares 861,393 Share Price $15.00 Est. Cost/Share $15.00 Unrealized @ Report Date —

— SCPHARMACEUTICALS INC 0.6%

Value $10.36M Shares 3,247,005 Share Price $3.19 Est. Cost/Share $11.02 Unrealized @ Report Date —

— ODONATE THERAPEUTICS INC 0.4%

Value $7.338M Shares 200,000 Share Price $36.69 Est. Cost/Share $36.69 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ASND	ASCENDIS PHARMA A S	4,132,442	$476M	25.5%	$115.15	$17.96	—	SPONSORED ADR	04351P101
WVE	WAVE LIFE SCIENCES LTD	7,775,207	$203M	10.9%	$26.09 *	$17.26	+62.5%	SHS	Y95308105
—	ZOGENIX INC	3,722,504	$178M	9.5%	$47.78	$37.11	—	COM NEW	98978L204
—	RA PHARMACEUTICALS INC	4,858,260	$137M	7.4%	$28.19	$8.41	—	COM	74933V108
—	SYNTHORX INC	9,724,598	$131M	7.1%	$13.51	$17.38	—	COM	87167A103
—	EIDOS THERAPEUTICS INC	2,162,671	$113M	6.1%	$52.12	$20.34	—	COM	28249H104
—	ORCHARD THERAPEUTICS PLC	5,108,330	$71.47M	3.8%	$13.99	$15.84	—	ADS	68570P101
TGTX	TG THERAPEUTICS INC	6,880,323	$59.52M	3.2%	$8.65 *	$12.35	-38.8%	COM	88322Q108
—	MYOVANT SCIENCES LTD	6,545,642	$59.24M	3.2%	$9.05	$12.18	—	COM	G637AM102
CRNX	CRINETICS PHARMACEUTICALS INC	1,875,209	$46.88M	2.5%	$25.00	$29.55	-16.2%	COM	22663K107
RYTM	RHYTHM PHARMACEUTICALS INC	1,884,782	$41.47M	2.2%	$22.00 *	$28.23	-10.6%	COM	76243J105
—	DICERNA PHARMACEUTICALS INC	2,456,669	$38.69M	2.1%	$15.75	$18.43	—	COM	253031108
ARVN	ARVINAS INC	1,688,412	$37.13M	2.0%	$21.99 *	$16.46	+27.7%	COM	04335A105
—	PREVAIL THERAPEUTICS INC	2,743,625	$36.22M	1.9%	$13.20	$13.20	—	COM	74140Y101
AXSM	AXSOME THERAPEUTICS INC	1,340,828	$34.53M	1.9%	$25.75 *	$9.29	+115.9%	COM	05464T104
STOK	STOKE THERAPEUTICS INC	1,119,963	$32.67M	1.8%	$29.17 *	$26.85	0.0%	COM	86150R107
—	KALA PHARMACEUTICALS INC	4,537,478	$28.95M	1.6%	$6.38	$13.25	—	COM	483119103
—	SHOCKWAVE MED INC	495,608	$28.29M	1.5%	$57.09	$33.47	—	COM	82489T104
—	PRECISION BIOSCIENCES INC	1,842,366	$24.41M	1.3%	$13.25	$17.95	—	COM	74019P108
—	SOLID BIOSCIENCES INC	2,689,444	$21.29M	1.1%	$7.92	$7.50	—	COM	83422E105
ALEC	ALECTOR INC	1,000,000	$19M	1.0%	$19.00 *	$18.92	+7.3%	COM	014442107
—	G1 THERAPEUTICS INC	483,990	$14.84M	0.8%	$30.66	$20.11	—	COM	3621LQ109
—	X4 PHARMACEUTICALS INC	861,393	$12.92M	0.7%	$15.00	$15.00	—	COM	98420X103
—	SCPHARMACEUTICALS INC	3,247,005	$10.36M	0.6%	$3.19	$11.02	—	COM	810648105
—	ODONATE THERAPEUTICS INC	200,000	$7.338M	0.4%	$36.69	$36.69	—	COM	676079106