RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q1 2019 (← Previous) (Next →)

Filing Date: May 15, 2019

Total Value: $2.319B (100.0% shares, 0.0% debt)

Holdings (29)

ASND ASCENDIS PHARMA A S 21.0%

Value $486M Shares 4,132,442 Share Price $117.70 Est. Cost/Share $17.96 Unrealized @ Report Date —

WVE WAVE LIFE SCIENCES LTD 13.0%

Value $302M Shares 7,775,207 Share Price $38.85 * Est. Cost/Share $17.26 Unrealized @ Report Date +135.1%

— SYNTHORX INC 8.5%

Value $198M Shares 9,724,598 Share Price $20.37 Est. Cost/Share $17.38 Unrealized @ Report Date —

— ZOGENIX INC 5.7%

Value $131M Shares 2,382,168 Share Price $55.01 Est. Cost/Share $31.10 Unrealized @ Report Date —

— RA PHARMACEUTICALS INC 4.7%

Value $109M Shares 4,858,260 Share Price $22.40 Est. Cost/Share $8.41 Unrealized @ Report Date —

IFRX INFLARX NV 4.6%

Value $106M Shares 2,810,708 Share Price $37.79 Est. Cost/Share $25.52 Unrealized @ Report Date +46.0%

— ORCHARD THERAPEUTICS PLC 3.9%

Value $91.34M Shares 5,108,330 Share Price $17.88 Est. Cost/Share $15.84 Unrealized @ Report Date —

— EIDOS THERAPEUTICS INC 3.9%

Value $91.07M Shares 2,162,671 Share Price $42.11 Est. Cost/Share $20.34 Unrealized @ Report Date —

— MYOVANT SCIENCES LTD 3.6%

Value $84.6M Shares 3,544,227 Share Price $23.87 Est. Cost/Share $14.83 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 3.0%

Value $70.49M Shares 8,659,983 Share Price $8.14 * Est. Cost/Share $7.30 Unrealized @ Report Date +17.3%

TGTX TG THERAPEUTICS INC 2.8%

Value $65.92M Shares 8,198,337 Share Price $8.04 * Est. Cost/Share $12.35 Unrealized @ Report Date -56.2%

— SAGE THERAPEUTICS INC 2.6%

Value $61.08M Shares 384,001 Share Price $159.05 Est. Cost/Share $159.05 Unrealized @ Report Date —

RYTM RHYTHM PHARMACEUTICALS INC 2.2%

Value $51.66M Shares 1,884,782 Share Price $27.41 * Est. Cost/Share $28.23 Unrealized @ Report Date +1.8%

AXSM AXSOME THERAPEUTICS INC 2.0%

Value $46.87M Shares 3,293,789 Share Price $14.23 * Est. Cost/Share $9.29 Unrealized @ Report Date 0.0%

CRNX CRINETICS PHARMACEUTICALS INC 1.8%

Value $42.68M Shares 1,875,209 Share Price $22.76 * Est. Cost/Share $29.55 Unrealized @ Report Date -16.8%

KALV KALVISTA PHARMACEUTICALS INC 1.8%

Value $41.24M Shares 1,441,070 Share Price $28.62 * Est. Cost/Share $9.16 Unrealized @ Report Date +136.6%

— KALA PHARMACEUTICALS INC 1.6%

Value $37.52M Shares 4,537,478 Share Price $8.27 Est. Cost/Share $13.25 Unrealized @ Report Date —

— MOMENTA PHARMACEUTICALS INC 1.6%

Value $37.25M Shares 2,563,657 Share Price $14.53 Est. Cost/Share $16.77 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 1.6%

Value $35.99M Shares 2,456,669 Share Price $14.65 Est. Cost/Share $18.43 Unrealized @ Report Date —

— EIGER BIOPHARMACEUTICALS INC 1.5%

Value $33.77M Shares 2,415,458 Share Price $13.98 Est. Cost/Share $10.16 Unrealized @ Report Date —

— PRECISION BIOSCIENCES INC 1.4%

Value $33.07M Shares 1,842,366 Share Price $17.95 Est. Cost/Share $17.95 Unrealized @ Report Date —

ARVN ARVINAS INC 1.4%

Value $31.56M Shares 2,138,412 Share Price $14.76 * Est. Cost/Share $16.46 Unrealized @ Report Date +7.8%

MRNA MODERNA INC 1.3%

Value $30.81M Shares 1,513,929 Share Price $20.35 * Est. Cost/Share $16.43 Unrealized @ Report Date +12.9%

IOVA IOVANCE BIOTHERAPEUTICS INC 1.1%

Value $24.83M Shares 2,610,510 Share Price $9.51 * Est. Cost/Share $11.82 Unrealized @ Report Date -17.8%

— SOLID BIOSCIENCES INC 1.1%

Value $24.74M Shares 2,689,444 Share Price $9.20 Est. Cost/Share $7.50 Unrealized @ Report Date —

ALEC ALECTOR INC 0.8%

Value $18.72M Shares 1,000,000 Share Price $18.72 Est. Cost/Share $18.92 Unrealized @ Report Date 0.0%

— SHOCKWAVE MED INC 0.7%

Value $16.59M Shares 495,608 Share Price $33.47 Est. Cost/Share $33.47 Unrealized @ Report Date —

— SCPHARMACEUTICALS INC 0.4%

Value $8.571M Shares 2,857,143 Share Price $3.00 Est. Cost/Share $12.09 Unrealized @ Report Date —

— G1 THERAPEUTICS INC 0.3%

Value $6.027M Shares 363,051 Share Price $16.60 Est. Cost/Share $16.60 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ASND	ASCENDIS PHARMA A S	4,132,442	$486M	21.0%	$117.70	$17.96	—	SPONSORED ADR	04351P101
WVE	WAVE LIFE SCIENCES LTD	7,775,207	$302M	13.0%	$38.85 *	$17.26	+135.1%	SHS	Y95308105
—	SYNTHORX INC	9,724,598	$198M	8.5%	$20.37	$17.38	—	COM	87167A103
—	ZOGENIX INC	2,382,168	$131M	5.7%	$55.01	$31.10	—	COM NEW	98978L204
—	RA PHARMACEUTICALS INC	4,858,260	$109M	4.7%	$22.40	$8.41	—	COM	74933V108
IFRX	INFLARX NV	2,810,708	$106M	4.6%	$37.79	$25.52	+46.0%	COM	N44821101
—	ORCHARD THERAPEUTICS PLC	5,108,330	$91.34M	3.9%	$17.88	$15.84	—	ADS	68570P101
—	EIDOS THERAPEUTICS INC	2,162,671	$91.07M	3.9%	$42.11	$20.34	—	COM	28249H104
—	MYOVANT SCIENCES LTD	3,544,227	$84.6M	3.6%	$23.87	$14.83	—	COM	G637AM102
BCRX	BIOCRYST PHARMACEUTICALS	8,659,983	$70.49M	3.0%	$8.14 *	$7.30	+17.3%	COM	09058V103
TGTX	TG THERAPEUTICS INC	8,198,337	$65.92M	2.8%	$8.04 *	$12.35	-56.2%	COM	88322Q108
—	SAGE THERAPEUTICS INC	384,001	$61.08M	2.6%	$159.05	$159.05	—	COM	78667J108
RYTM	RHYTHM PHARMACEUTICALS INC	1,884,782	$51.66M	2.2%	$27.41 *	$28.23	+1.8%	COM	76243J105
AXSM	AXSOME THERAPEUTICS INC	3,293,789	$46.87M	2.0%	$14.23 *	$9.29	0.0%	COM	05464T104
CRNX	CRINETICS PHARMACEUTICALS INC	1,875,209	$42.68M	1.8%	$22.76 *	$29.55	-16.8%	COM	22663K107
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$41.24M	1.8%	$28.62 *	$9.16	+136.6%	COM	483497103
—	KALA PHARMACEUTICALS INC	4,537,478	$37.52M	1.6%	$8.27	$13.25	—	COM	483119103
—	MOMENTA PHARMACEUTICALS INC	2,563,657	$37.25M	1.6%	$14.53	$16.77	—	COM	60877T100
—	DICERNA PHARMACEUTICALS INC	2,456,669	$35.99M	1.6%	$14.65	$18.43	—	COM	253031108
—	EIGER BIOPHARMACEUTICALS INC	2,415,458	$33.77M	1.5%	$13.98	$10.16	—	COM	28249U105
—	PRECISION BIOSCIENCES INC	1,842,366	$33.07M	1.4%	$17.95	$17.95	—	COM	74019P108
ARVN	ARVINAS INC	2,138,412	$31.56M	1.4%	$14.76 *	$16.46	+7.8%	COM	04335A105
MRNA	MODERNA INC	1,513,929	$30.81M	1.3%	$20.35 *	$16.43	+12.9%	COM	60770K107
IOVA	IOVANCE BIOTHERAPEUTICS INC	2,610,510	$24.83M	1.1%	$9.51 *	$11.82	-17.8%	COM	462260100
—	SOLID BIOSCIENCES INC	2,689,444	$24.74M	1.1%	$9.20	$7.50	—	COM	83422E105
ALEC	ALECTOR INC	1,000,000	$18.72M	0.8%	$18.72	$18.92	0.0%	COM	014442107
—	SHOCKWAVE MED INC	495,608	$16.59M	0.7%	$33.47	$33.47	—	COM	82489T104
—	SCPHARMACEUTICALS INC	2,857,143	$8.571M	0.4%	$3.00	$12.09	—	COM	810648105
—	G1 THERAPEUTICS INC	363,051	$6.027M	0.3%	$16.60	$16.60	—	COM	3621LQ109