RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q3 2019 (← Previous) (Next →)

Filing Date: Nov 14, 2019

Total Value: $1.678B (100.0% shares, 0.0% debt)

Holdings (32)

ASND ASCENDIS PHARMA A S 23.7%

Value $398M Shares 4,132,442 Share Price $96.32 Est. Cost/Share $17.96 Unrealized @ Report Date —

WVE WAVE LIFE SCIENCES LTD 9.5%

Value $160M Shares 7,775,207 Share Price $20.53 * Est. Cost/Share $17.26 Unrealized @ Report Date +32.9%

— SYNTHORX INC 9.4%

Value $158M Shares 9,724,598 Share Price $16.27 Est. Cost/Share $17.38 Unrealized @ Report Date —

— RA PHARMACEUTICALS INC 6.8%

Value $115M Shares 4,858,260 Share Price $23.65 Est. Cost/Share $8.41 Unrealized @ Report Date —

— ZOGENIX INC 5.4%

Value $90.52M Shares 2,260,751 Share Price $40.04 Est. Cost/Share $37.11 Unrealized @ Report Date —

— EIDOS THERAPEUTICS INC 4.6%

Value $77.79M Shares 2,162,671 Share Price $35.97 Est. Cost/Share $20.34 Unrealized @ Report Date —

RYTM RHYTHM PHARMACEUTICALS INC 4.4%

Value $73.89M Shares 3,422,312 Share Price $21.59 Est. Cost/Share $25.19 Unrealized @ Report Date -14.8%

— SATSUMA PHARMACEUTICALS INC 4.2%

Value $70.28M Shares 4,681,858 Share Price $15.01 Est. Cost/Share $15.01 Unrealized @ Report Date —

— ORCHARD THERAPEUTICS PLC 3.7%

Value $62.07M Shares 5,224,475 Share Price $11.88 Est. Cost/Share $15.75 Unrealized @ Report Date —

— SOLID BIOSCIENCES INC 2.8%

Value $47.27M Shares 4,571,164 Share Price $10.34 Est. Cost/Share $8.67 Unrealized @ Report Date —

— RETROPHIN INC 2.8%

Value $46.22M Shares 3,987,560 Share Price $11.59 Est. Cost/Share $11.59 Unrealized @ Report Date —

— PREVAIL THERAPEUTICS INC 2.5%

Value $41.3M Shares 3,363,605 Share Price $12.28 Est. Cost/Share $13.03 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 2.3%

Value $38.63M Shares 6,880,323 Share Price $5.61 * Est. Cost/Share $12.35 Unrealized @ Report Date -43.5%

ARVN ARVINAS INC 2.1%

Value $35.85M Shares 1,663,512 Share Price $21.55 * Est. Cost/Share $16.46 Unrealized @ Report Date +49.1%

— DICERNA PHARMACEUTICALS INC 2.1%

Value $35.28M Shares 2,456,669 Share Price $14.36 Est. Cost/Share $18.43 Unrealized @ Report Date —

— MYOVANT SCIENCES LTD 1.9%

Value $32.07M Shares 6,166,875 Share Price $5.20 Est. Cost/Share $12.18 Unrealized @ Report Date —

CRNX CRINETICS PHARMACEUTICALS INC 1.7%

Value $28.2M Shares 1,875,209 Share Price $15.04 * Est. Cost/Share $29.55 Unrealized @ Report Date -34.2%

STOK STOKE THERAPEUTICS INC 1.4%

Value $24.07M Shares 1,119,963 Share Price $21.49 * Est. Cost/Share $26.85 Unrealized @ Report Date +3.8%

— SCPHARMACEUTICALS INC 1.1%

Value $19.06M Shares 3,247,005 Share Price $5.87 Est. Cost/Share $11.02 Unrealized @ Report Date —

— KALA PHARMACEUTICALS INC 1.0%

Value $17.27M Shares 4,537,478 Share Price $3.80 Est. Cost/Share $13.25 Unrealized @ Report Date —

— PRECISION BIOSCIENCES INC 0.9%

Value $15.46M Shares 1,842,366 Share Price $8.39 Est. Cost/Share $17.95 Unrealized @ Report Date —

KOD KODIAK SCIENCES INC 0.9%

Value $14.74M Shares 1,025,165 Share Price $14.38 * Est. Cost/Share $13.06 Unrealized @ Report Date 0.0%

ALEC ALECTOR INC 0.9%

Value $14.42M Shares 1,000,000 Share Price $14.42 * Est. Cost/Share $18.92 Unrealized @ Report Date -4.6%

AXSM AXSOME THERAPEUTICS INC 0.8%

Value $13.45M Shares 664,385 Share Price $20.24 * Est. Cost/Share $9.29 Unrealized @ Report Date +176.7%

— PORTOLA PHARMACEUTICALS INC 0.7%

Value $11.52M Shares 429,399 Share Price $26.82 Est. Cost/Share $26.82 Unrealized @ Report Date —

— DYNAVAX TECHNOLOGIES CORP 0.5%

Value $8.458M Shares 2,365,912 Share Price $3.57 Est. Cost/Share $3.57 Unrealized @ Report Date —

— IGM BIOSCIENCES INC 0.5%

Value $8.278M Shares 466,368 Share Price $17.75 Est. Cost/Share $17.75 Unrealized @ Report Date —

— X4 PHARMACEUTICALS INC 0.4%

Value $6.077M Shares 478,107 Share Price $12.71 Est. Cost/Share $15.00 Unrealized @ Report Date —

— ODONATE THERAPEUTICS INC 0.3%

Value $5.206M Shares 200,000 Share Price $26.03 Est. Cost/Share $36.69 Unrealized @ Report Date —

— CHIMERIX INC 0.2%

Value $4.188M Shares 1,782,202 Share Price $2.35 Est. Cost/Share $2.35 Unrealized @ Report Date —

— ESSA PHARMA INC 0.2%

Value $3.37M Shares 1,000,000 Share Price $3.37 Est. Cost/Share $3.37 Unrealized @ Report Date —

— SENSEONICS HLDGS INC 0.2%

Value $2.696M Shares 2,727,273 Share Price $0.99 Est. Cost/Share $0.99 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ASND	ASCENDIS PHARMA A S	4,132,442	$398M	23.7%	$96.32	$17.96	—	SPONSORED ADR	04351P101
WVE	WAVE LIFE SCIENCES LTD	7,775,207	$160M	9.5%	$20.53 *	$17.26	+32.9%	SHS	Y95308105
—	SYNTHORX INC	9,724,598	$158M	9.4%	$16.27	$17.38	—	COM	87167A103
—	RA PHARMACEUTICALS INC	4,858,260	$115M	6.8%	$23.65	$8.41	—	COM	74933V108
—	ZOGENIX INC	2,260,751	$90.52M	5.4%	$40.04	$37.11	—	COM NEW	98978L204
—	EIDOS THERAPEUTICS INC	2,162,671	$77.79M	4.6%	$35.97	$20.34	—	COM	28249H104
RYTM	RHYTHM PHARMACEUTICALS INC	3,422,312	$73.89M	4.4%	$21.59	$25.19	-14.8%	COM	76243J105
—	SATSUMA PHARMACEUTICALS INC	4,681,858	$70.28M	4.2%	$15.01	$15.01	—	COM	80405P107
—	ORCHARD THERAPEUTICS PLC	5,224,475	$62.07M	3.7%	$11.88	$15.75	—	ADS	68570P101
—	SOLID BIOSCIENCES INC	4,571,164	$47.27M	2.8%	$10.34	$8.67	—	COM	83422E105
—	RETROPHIN INC	3,987,560	$46.22M	2.8%	$11.59	$11.59	—	COM	761299106
—	PREVAIL THERAPEUTICS INC	3,363,605	$41.3M	2.5%	$12.28	$13.03	—	COM	74140Y101
TGTX	TG THERAPEUTICS INC	6,880,323	$38.63M	2.3%	$5.61 *	$12.35	-43.5%	COM	88322Q108
ARVN	ARVINAS INC	1,663,512	$35.85M	2.1%	$21.55 *	$16.46	+49.1%	COM	04335A105
—	DICERNA PHARMACEUTICALS INC	2,456,669	$35.28M	2.1%	$14.36	$18.43	—	COM	253031108
—	MYOVANT SCIENCES LTD	6,166,875	$32.07M	1.9%	$5.20	$12.18	—	COM	G637AM102
CRNX	CRINETICS PHARMACEUTICALS INC	1,875,209	$28.2M	1.7%	$15.04 *	$29.55	-34.2%	COM	22663K107
STOK	STOKE THERAPEUTICS INC	1,119,963	$24.07M	1.4%	$21.49 *	$26.85	+3.8%	COM	86150R107
—	SCPHARMACEUTICALS INC	3,247,005	$19.06M	1.1%	$5.87	$11.02	—	COM	810648105
—	KALA PHARMACEUTICALS INC	4,537,478	$17.27M	1.0%	$3.80	$13.25	—	COM	483119103
—	PRECISION BIOSCIENCES INC	1,842,366	$15.46M	0.9%	$8.39	$17.95	—	COM	74019P108
KOD	KODIAK SCIENCES INC	1,025,165	$14.74M	0.9%	$14.38 *	$13.06	0.0%	COM	50015M109
ALEC	ALECTOR INC	1,000,000	$14.42M	0.9%	$14.42 *	$18.92	-4.6%	COM	014442107
AXSM	AXSOME THERAPEUTICS INC	664,385	$13.45M	0.8%	$20.24 *	$9.29	+176.7%	COM	05464T104
—	PORTOLA PHARMACEUTICALS INC	429,399	$11.52M	0.7%	$26.82	$26.82	—	COM	737010108
—	DYNAVAX TECHNOLOGIES CORP	2,365,912	$8.458M	0.5%	$3.57	$3.57	—	COM NEW	268158201
—	IGM BIOSCIENCES INC	466,368	$8.278M	0.5%	$17.75	$17.75	—	COM	449585108
—	X4 PHARMACEUTICALS INC	478,107	$6.077M	0.4%	$12.71	$15.00	—	COM	98420X103
—	ODONATE THERAPEUTICS INC	200,000	$5.206M	0.3%	$26.03	$36.69	—	COM	676079106
—	CHIMERIX INC	1,782,202	$4.188M	0.2%	$2.35	$2.35	—	COM	16934W106
—	ESSA PHARMA INC	1,000,000	$3.37M	0.2%	$3.37	$3.37	—	COM NEW	29668H708
—	SENSEONICS HLDGS INC	2,727,273	$2.696M	0.2%	$0.99	$0.99	—	COM	81727U105