GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q1 2021 (← Previous) (Next →)

Filing Date: May 17, 2021

Total Value ($000): $483,855 (100.0% shares, 0.0% debt)

Holdings (28)

MGNX MACROGENICS INC 8.9%

Value ($000) $42,998 Shares 1,350,000 Est. Cost $17.94 Unrealized +35.4%

RCKT ROCKET PHARMACEUTICALS INC 7.0%

Value ($000) $33,721 Shares 760,000 Est. Cost $37.91 Unrealized +44.8%

IOVA IOVANCE BIOTHERAPEUTICS INC 6.1%

Value ($000) $29,444 Shares 930,000 Est. Cost $18.95 Unrealized +118.7%

— SAGE THERAPEUTICS INC 5.9%

Value ($000) $28,599 Shares 382,085 Est. Cost $46.88 Unrealized —

— INTERSECT ENT INC 5.8%

Value ($000) $27,828 Shares 1,332,773 Est. Cost $19.16 Unrealized —

EXEL EXELIXIS INC 5.6%

Value ($000) $27,133 Shares 1,201,100 Est. Cost $21.93 Unrealized +3.0%

UTHR UNITED THERAPEUTICS CORP DEL 5.4%

Value ($000) $26,162 Shares 156,406 Est. Cost $89.14 Unrealized +87.0%

— ARENA PHARMACEUTICALS INC 5.4%

Value ($000) $26,082 Shares 375,870 Est. Cost $57.75 Unrealized —

PODD INSULET CORP 4.8%

Value ($000) $23,378 Shares 89,600 Est. Cost $254.61 Unrealized +5.2%

— MIRATI THERAPEUTICS INC 4.8%

Value ($000) $23,126 Shares 135,000 Est. Cost $171.30 Unrealized —

BIIB BIOGEN INC 4.3%

Value ($000) $20,981 Shares 75,000 Est. Cost $269.69 Unrealized 0.0%

COLL COLLEGIUM PHARMACEUTICAL INC 4.2%

Value ($000) $20,415 Shares 861,410 Est. Cost $21.69 Unrealized +9.5%

— CONSTELLATION PHARMCETICLS I 4.2%

Value ($000) $20,406 Shares 872,415 Est. Cost $35.95 Unrealized —

— KADMON HLDGS INC 3.8%

Value ($000) $18,497 Shares 4,755,000 Est. Cost $4.16 Unrealized —

OCUL OCULAR THERAPEUTIX INC 3.4%

Value ($000) $16,525 Shares 1,007,012 Est. Cost $15.51 Unrealized +24.2%

TVTX TRAVERE THERAPEUTICS INC 3.1%

Value ($000) $14,825 Shares 593,712 Est. Cost $27.63 Unrealized 0.0%

LNTH LANTHEUS HLDGS INC 2.9%

Value ($000) $13,880 Shares 649,516 Est. Cost $18.14 Unrealized 0.0%

PBYI PUMA BIOTECHNOLOGY INC 2.6%

Value ($000) $12,636 Shares 1,300,000 Est. Cost $10.19 Unrealized +9.6%

— NEVRO CORP 2.3%

Value ($000) $11,160 Shares 80,000 Est. Cost $139.50 Unrealized —

IFRX INFLARX NV 1.8%

Value ($000) $8,580 Shares 2,200,000 Est. Cost $5.12 Unrealized 0.0%

ACAD ACADIA PHARMACEUTICALS INC 1.7%

Value ($000) $8,029 Shares 311,217 Est. Cost $30.25 Unrealized +45.5%

LUNG PULMONX CORP 1.1%

Value ($000) $5,230 Shares 114,345 Est. Cost $52.64 Unrealized +9.0%

— REDHILL BIOPHARMA LTD 1.1%

Value ($000) $5,163 Shares 705,305 Est. Cost $7.32 Unrealized —

— PROMETHEUS BIOSCIENCES INC 0.9%

Value ($000) $4,565 Shares 250,000 Est. Cost $18.26 Unrealized —

— Y-MABS THERAPEUTICS INC 0.9%

Value ($000) $4,536 Shares 150,000 Est. Cost $30.24 Unrealized —

GERN GERON CORP 0.9%

Value ($000) $4,124 Shares 2,610,000 Est. Cost $1.49 Unrealized +19.5%

— AEGLEA BIOTHERAPEUTICS INC 0.8%

Value ($000) $3,983 Shares 502,900 Est. Cost $7.92 Unrealized —

— TRICIDA INC 0.4%

Value ($000) $1,849 Shares 349,600 Est. Cost $5.29 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
MGNX	MACROGENICS INC	1,350,000	$42,998	8.9%	$17.94	+35.4%	COM	556099109
RCKT	ROCKET PHARMACEUTICALS INC	760,000	$33,721	7.0%	$37.91	+44.8%	COM	77313F106
IOVA	IOVANCE BIOTHERAPEUTICS INC	930,000	$29,444	6.1%	$18.95	+118.7%	COM	462260100
—	SAGE THERAPEUTICS INC	382,085	$28,599	5.9%	$46.88	—	COM	78667J108
—	INTERSECT ENT INC	1,332,773	$27,828	5.8%	$19.16	—	COM	46071F103
EXEL	EXELIXIS INC	1,201,100	$27,133	5.6%	$21.93	+3.0%	COM	30161Q104
UTHR	UNITED THERAPEUTICS CORP DEL	156,406	$26,162	5.4%	$89.14	+87.0%	COM	91307C102
—	ARENA PHARMACEUTICALS INC	375,870	$26,082	5.4%	$57.75	—	COM NEW	040047607
PODD	INSULET CORP	89,600	$23,378	4.8%	$254.61	+5.2%	COM	45784P101
—	MIRATI THERAPEUTICS INC	135,000	$23,126	4.8%	$171.30	—	COM	60468T105
BIIB	BIOGEN INC	75,000	$20,981	4.3%	$269.69	0.0%	COM	09062X103
COLL	COLLEGIUM PHARMACEUTICAL INC	861,410	$20,415	4.2%	$21.69	+9.5%	COM	19459J104
—	CONSTELLATION PHARMCETICLS I	872,415	$20,406	4.2%	$35.95	—	COM	210373106
—	KADMON HLDGS INC	4,755,000	$18,497	3.8%	$4.16	—	COM	48283N106
OCUL	OCULAR THERAPEUTIX INC	1,007,012	$16,525	3.4%	$15.51	+24.2%	COM	67576A100
TVTX	TRAVERE THERAPEUTICS INC	593,712	$14,825	3.1%	$27.63	0.0%	COM	89422G107
LNTH	LANTHEUS HLDGS INC	649,516	$13,880	2.9%	$18.14	0.0%	COM	516544103
PBYI	PUMA BIOTECHNOLOGY INC	1,300,000	$12,636	2.6%	$10.19	+9.6%	COM	74587V107
—	NEVRO CORP	80,000	$11,160	2.3%	$139.50	—	COM	64157F103
IFRX	INFLARX NV	2,200,000	$8,580	1.8%	$5.12	0.0%	COM	N44821101
ACAD	ACADIA PHARMACEUTICALS INC	311,217	$8,029	1.7%	$30.25	+45.5%	COM	004225108
LUNG	PULMONX CORP	114,345	$5,230	1.1%	$52.64	+9.0%	COM	745848101
—	REDHILL BIOPHARMA LTD	705,305	$5,163	1.1%	$7.32	—	SPONSORED ADS	757468103
—	PROMETHEUS BIOSCIENCES INC	250,000	$4,565	0.9%	$18.26	—	COM	74349U108
—	Y-MABS THERAPEUTICS INC	150,000	$4,536	0.9%	$30.24	—	COM	984241109
GERN	GERON CORP	2,610,000	$4,124	0.9%	$1.49	+19.5%	COM	374163103
—	AEGLEA BIOTHERAPEUTICS INC	502,900	$3,983	0.8%	$7.92	—	COM	00773J103
—	TRICIDA INC	349,600	$1,849	0.4%	$5.29	—	COM	89610F101