GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q4 2020 (← Previous) (Next →)

Filing Date: Feb 16, 2021

Total Value: $616M (100.0% shares, 0.0% debt)

Holdings (33)

— GW PHARMACEUTICALS PLC 7.3%

Value $45.01M Shares 390,000 Est. Cost $93.52 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 6.9%

Value $42.57M Shares 917,427 Est. Cost $18.64 Unrealized +113.0%

— SAGE THERAPEUTICS INC 6.4%

Value $39.31M Shares 454,417 Est. Cost $46.88 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 6.3%

Value $38.52M Shares 720,502 Est. Cost $30.25 Unrealized +64.1%

RCKT ROCKET PHARMACEUTICALS INC 6.2%

Value $38.39M Shares 700,000 Est. Cost $36.45 Unrealized 0.0%

— ZYMEWORKS INC 6.1%

Value $37.8M Shares 799,722 Est. Cost $8101.10 Unrealized —

— INTERSECT ENT INC 4.8%

Value $29.84M Shares 1,302,871 Est. Cost $19.12 Unrealized —

— CONSTELLATION PHARMCETICLS I 4.8%

Value $29.51M Shares 1,024,800 Est. Cost $35.95 Unrealized —

MGNX MACROGENICS INC 4.6%

Value $28.33M Shares 1,239,287 Est. Cost $17.37 Unrealized +32.5%

VCEL VERICEL CORP 4.5%

Value $27.79M Shares 900,000 Est. Cost $13.53 Unrealized +75.9%

— ARENA PHARMACEUTICALS INC 4.3%

Value $26.52M Shares 345,120 Est. Cost $56.72 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 4.2%

Value $25.79M Shares 595,473 Est. Cost $61.75 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 3.7%

Value $22.77M Shares 150,000 Est. Cost $85.83 Unrealized +52.9%

OCUL OCULAR THERAPEUTIX INC 2.9%

Value $17.72M Shares 856,162 Est. Cost $14.85 Unrealized 0.0%

— KADMON HLDGS INC 2.8%

Value $16.95M Shares 4,083,909 Est. Cost $4.21 Unrealized —

PODD INSULET CORP 2.5%

Value $15.34M Shares 60,000 Est. Cost $248.10 Unrealized 0.0%

TBPH THERAVANCE BIOPHARMA INC 2.4%

Value $14.65M Shares 824,580 Est. Cost $17.95 Unrealized 0.0%

ARVN ARVINAS INC 2.3%

Value $13.94M Shares 164,150 Est. Cost $34.48 Unrealized 0.0%

PBYI PUMA BIOTECHNOLOGY INC 2.2%

Value $13.34M Shares 1,300,000 Est. Cost $10.19 Unrealized -0.6%

— MERSANA THERAPEUTICS INC 2.1%

Value $12.97M Shares 487,452 Est. Cost $26.61 Unrealized —

PRTA PROTHENA CORP PLC 1.9%

Value $11.74M Shares 977,647 Est. Cost $10.02 Unrealized +18.0%

EXEL EXELIXIS INC 1.5%

Value $9.533M Shares 475,000 Est. Cost $20.93 Unrealized 0.0%

— CALITHERA BIOSCIENCES INC 1.5%

Value $9.059M Shares 1,845,000 Est. Cost $4.87 Unrealized —

COLL COLLEGIUM PHARMACEUTICAL INC 1.4%

Value $8.44M Shares 421,383 Est. Cost $19.53 Unrealized 0.0%

— FORMA THERAPEUTICS HLDGS INC 1.3%

Value $8.25M Shares 236,400 Est. Cost $34.90 Unrealized —

GERN GERON CORP 1.3%

Value $8.038M Shares 5,055,189 Est. Cost $1.49 Unrealized +21.9%

— FIBROGEN INC 1.0%

Value $6.176M Shares 166,500 Est. Cost — Unrealized —

LUNG PULMONX CORP 0.7%

Value $4.441M Shares 64,345 Est. Cost $48.97 Unrealized 0.0%

IONS IONIS PHARMACEUTICALS INC 0.7%

Value $4.241M Shares 75,000 Est. Cost $49.83 Unrealized 0.0%

SPRY SILVERBACK THERAPEUTICS INC 0.5%

Value $3.244M Shares 70,000 Est. Cost $33.40 Unrealized 0.0%

— CALITHERA BIOSCIENCES INC 0.4%

Value $2.455M Shares 500,000 Est. Cost $4.87 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 0.4%

Value $2.42M Shares 175,000 Est. Cost $14.49 Unrealized +0.5%

— MILLENDO THERAPEUTICS INC 0.1%

Value $578K Shares 270,000 Est. Cost $7.64 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	GW PHARMACEUTICALS PLC	390,000	$45.01M	7.3%	$93.52	—	ADS	36197T103
IOVA	IOVANCE BIOTHERAPEUTICS INC	917,427	$42.57M	6.9%	$18.64	+113.0%	COM	462260100
—	SAGE THERAPEUTICS INC	454,417	$39.31M	6.4%	$46.88	—	COM	78667J108
ACAD	ACADIA PHARMACEUTICALS INC	720,502	$38.52M	6.3%	$30.25	+64.1%	COM	004225108
RCKT	ROCKET PHARMACEUTICALS INC	700,000	$38.39M	6.2%	$36.45	0.0%	COM	77313F106
—	ZYMEWORKS INC	799,722	$37.8M	6.1%	$8101.10	—	COM	98985W102
—	INTERSECT ENT INC	1,302,871	$29.84M	4.8%	$19.12	—	COM	46071F103
—	CONSTELLATION PHARMCETICLS I	1,024,800	$29.51M	4.8%	$35.95	—	COM	210373106
MGNX	MACROGENICS INC	1,239,287	$28.33M	4.6%	$17.37	+32.5%	COM	556099109
VCEL	VERICEL CORP	900,000	$27.79M	4.5%	$13.53	+75.9%	COM	92346J108
—	ARENA PHARMACEUTICALS INC	345,120	$26.52M	4.3%	$56.72	—	COM NEW	040047607
—	GLOBAL BLOOD THERAPEUTICS IN	595,473	$25.79M	4.2%	$61.75	—	COM	37890U108
UTHR	UNITED THERAPEUTICS CORP DEL	150,000	$22.77M	3.7%	$85.83	+52.9%	COM	91307C102
OCUL	OCULAR THERAPEUTIX INC	856,162	$17.72M	2.9%	$14.85	0.0%	COM	67576A100
—	KADMON HLDGS INC	4,083,909	$16.95M	2.8%	$4.21	—	COM	48283N106
PODD	INSULET CORP	60,000	$15.34M	2.5%	$248.10	0.0%	COM	45784P101
TBPH	THERAVANCE BIOPHARMA INC	824,580	$14.65M	2.4%	$17.95	0.0%	COM	G8807B106
ARVN	ARVINAS INC	164,150	$13.94M	2.3%	$34.48	0.0%	COM	04335A105
PBYI	PUMA BIOTECHNOLOGY INC	1,300,000	$13.34M	2.2%	$10.19	-0.6%	COM	74587V107
—	MERSANA THERAPEUTICS INC	487,452	$12.97M	2.1%	$26.61	—	COM	59045L106
PRTA	PROTHENA CORP PLC	977,647	$11.74M	1.9%	$10.02	+18.0%	SHS	G72800108
EXEL	EXELIXIS INC	475,000	$9.533M	1.5%	$20.93	0.0%	COM	30161Q104
—	CALITHERA BIOSCIENCES INC	1,845,000	$9.059M	1.5%	$4.87	—	COM	13089P101
COLL	COLLEGIUM PHARMACEUTICAL INC	421,383	$8.44M	1.4%	$19.53	0.0%	COM	19459J104
—	FORMA THERAPEUTICS HLDGS INC	236,400	$8.25M	1.3%	$34.90	—	SHS	34633R104
GERN	GERON CORP	5,055,189	$8.038M	1.3%	$1.49	+21.9%	COM	374163103
—	FIBROGEN INC	166,500	$6.176M	1.0%	—	—	Call	31572Q808
LUNG	PULMONX CORP	64,345	$4.441M	0.7%	$48.97	0.0%	COM	745848101
IONS	IONIS PHARMACEUTICALS INC	75,000	$4.241M	0.7%	$49.83	0.0%	COM	462222100
SPRY	SILVERBACK THERAPEUTICS INC	70,000	$3.244M	0.5%	$33.40	0.0%	COM	82835W108
—	CALITHERA BIOSCIENCES INC	500,000	$2.455M	0.4%	$4.87	—	Call	13089P101
AUPH	AURINIA PHARMACEUTICALS INC	175,000	$2.42M	0.4%	$14.49	+0.5%	COM	05156V102
—	MILLENDO THERAPEUTICS INC	270,000	$578K	0.1%	$7.64	—	COM	60040X103