GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q3 2024 (← Previous) (Next →)

Filing Date: Nov 13, 2024

Total Value: $340M (100.0% shares, 0.0% debt)

Holdings (30)

NGNE NEUROGENE INC 12.4%

Value $42.14M Shares 1,004,291 Est. Cost $14.51 Unrealized +167.3%

ABVX ABIVAX SA 7.2%

Value $24.52M Shares 2,128,773 Est. Cost $12.06 Unrealized —

PLRX PLIANT THERAPEUTICS INC 6.3%

Value $21.41M Shares 1,910,121 Est. Cost $16.18 Unrealized -22.7%

EOLS EVOLUS INC 5.6%

Value $18.95M Shares 1,170,000 Est. Cost $9.65 Unrealized +44.8%

VRDN VIRIDIAN THERAPEUTICS INC 5.0%

Value $17.06M Shares 750,000 Est. Cost $18.37 Unrealized -11.0%

CYTK CYTOKINETICS INC 4.9%

Value $16.68M Shares 316,000 Est. Cost $51.75 Unrealized +7.7%

KALV KALVISTA PHARMACEUTICALS INC 4.4%

Value $15.05M Shares 1,299,503 Est. Cost $11.67 Unrealized +7.8%

— DYNAVAX TECHNOLOGIES CORP 4.3%

Value $14.77M Shares 1,326,234 Est. Cost $11.86 Unrealized —

CNTX CONTEXT THERAPEUTICS INC 4.0%

Value $13.59M Shares 6,934,982 Est. Cost $1.72 Unrealized +28.7%

ZURA ZURA BIO LTD 3.9%

Value $13.25M Shares 3,263,672 Est. Cost $6.43 Unrealized -41.9%

ORKA ORUKA THERAPEUTICS INC 3.7%

Value $12.61M Shares 514,659 Est. Cost $34.79 Unrealized 0.0%

— MERUS N V 3.7%

Value $12.49M Shares 250,000 Est. Cost $52.47 Unrealized —

OLMA OLEMA PHARMACEUTICALS INC 3.5%

Value $11.94M Shares 1,000,000 Est. Cost $11.24 Unrealized +13.8%

IONS IONIS PHARMACEUTICALS INC 3.0%

Value $10.22M Shares 255,000 Est. Cost $41.01 Unrealized +13.4%

AUTL AUTOLUS THERAPEUTICS PLC 3.0%

Value $10.21M Shares 2,811,955 Est. Cost $4.46 Unrealized —

URGN UROGEN PHARMA LTD 2.8%

Value $9.637M Shares 758,786 Est. Cost $15.87 Unrealized -6.5%

— OPTINOSE INC 2.5%

Value $8.617M Shares 12,861,136 Est. Cost $1.52 Unrealized —

ACLX ARCELLX INC 2.5%

Value $8.351M Shares 100,000 Est. Cost $56.99 Unrealized +16.8%

ACLX ARCELLX INC 2.5%

Value $8.351M Shares 100,000 Est. Cost $56.99 Unrealized +16.8%

DNTH DIANTHUS THERAPEUTICS INC 2.2%

Value $7.529M Shares 275,000 Est. Cost $22.14 Unrealized +25.8%

OTLK OUTLOOK THERAPEUTICS INC 2.0%

Value $6.905M Shares 1,293,028 Est. Cost $8.08 Unrealized -9.4%

JSPR JASPER THERAPEUTICS INC 1.8%

Value $6.064M Shares 322,380 Est. Cost $17.76 Unrealized +12.1%

VYGR VOYAGER THERAPEUTICS INC 1.7%

Value $5.616M Shares 959,953 Est. Cost $7.91 Unrealized —

BBOT HELIX ACQUISITION CORP II 1.5%

Value $5.225M Shares 500,000 Est. Cost $10.35 Unrealized +0.1%

TCRX TSCAN THERAPEUTICS INC 1.5%

Value $5.062M Shares 1,016,375 Est. Cost $7.74 Unrealized -22.0%

— UNICYCIVE THERAPEUTICS INC 1.0%

Value $3.491M Shares 8,559,000 Est. Cost $0.41 Unrealized —

— PROMIS NEUROSCIENCES INC 1.0%

Value $3.488M Shares 2,790,698 Est. Cost $1.25 Unrealized —

RNAC CARTESIAN THERAPEUTICS INC 0.9%

Value $3.224M Shares 200,000 Est. Cost $15.62 Unrealized 0.0%

VTGN VISTAGEN THERAPEUTICS INC 0.6%

Value $2.029M Shares 674,075 Est. Cost $3.78 Unrealized -9.8%

CLYM ELIEM THERAPEUTICS INC 0.4%

Value $1.263M Shares 248,168 Est. Cost $7.07 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
NGNE	NEUROGENE INC	1,004,291	$42.14M	12.4%	$14.51	+167.3%	COM	64135M105
ABVX	ABIVAX SA	2,128,773	$24.52M	7.2%	$12.06	—	SPONSORED ADS	00370M103
PLRX	PLIANT THERAPEUTICS INC	1,910,121	$21.41M	6.3%	$16.18	-22.7%	COM	729139105
EOLS	EVOLUS INC	1,170,000	$18.95M	5.6%	$9.65	+44.8%	COM	30052C107
VRDN	VIRIDIAN THERAPEUTICS INC	750,000	$17.06M	5.0%	$18.37	-11.0%	COM	92790C104
CYTK	CYTOKINETICS INC	316,000	$16.68M	4.9%	$51.75	+7.7%	COM NEW	23282W605
KALV	KALVISTA PHARMACEUTICALS INC	1,299,503	$15.05M	4.4%	$11.67	+7.8%	COM	483497103
—	DYNAVAX TECHNOLOGIES CORP	1,326,234	$14.77M	4.3%	$11.86	—	COM NEW	268158201
CNTX	CONTEXT THERAPEUTICS INC	6,934,982	$13.59M	4.0%	$1.72	+28.7%	COM	21077P108
ZURA	ZURA BIO LTD	3,263,672	$13.25M	3.9%	$6.43	-41.9%	CLASS A ORD SHS	G9TY5A101
ORKA	ORUKA THERAPEUTICS INC	514,659	$12.61M	3.7%	$34.79	0.0%	COM	687604108
—	MERUS N V	250,000	$12.49M	3.7%	$52.47	—	COM	N5749R100
OLMA	OLEMA PHARMACEUTICALS INC	1,000,000	$11.94M	3.5%	$11.24	+13.8%	COM	68062P106
IONS	IONIS PHARMACEUTICALS INC	255,000	$10.22M	3.0%	$41.01	+13.4%	COM	462222100
AUTL	AUTOLUS THERAPEUTICS PLC	2,811,955	$10.21M	3.0%	$4.46	—	SPON ADS	05280R100
URGN	UROGEN PHARMA LTD	758,786	$9.637M	2.8%	$15.87	-6.5%	COM	M96088105
—	OPTINOSE INC	12,861,136	$8.617M	2.5%	$1.52	—	COM	68404V100
ACLX	ARCELLX INC	100,000	$8.351M	2.5%	$56.99	+16.8%	COMMON STOCK	03940C100
ACLX	ARCELLX INC	100,000	$8.351M	2.5%	$56.99	+16.8%	Put	03940C100
DNTH	DIANTHUS THERAPEUTICS INC	275,000	$7.529M	2.2%	$22.14	+25.8%	COM	252828108
OTLK	OUTLOOK THERAPEUTICS INC	1,293,028	$6.905M	2.0%	$8.08	-9.4%	COM	69012T305
JSPR	JASPER THERAPEUTICS INC	322,380	$6.064M	1.8%	$17.76	+12.1%	COM NEW	471871202
VYGR	VOYAGER THERAPEUTICS INC	959,953	$5.616M	1.7%	$7.91	—	COM	92915B106
BBOT	HELIX ACQUISITION CORP II	500,000	$5.225M	1.5%	$10.35	+0.1%	CL A ORD SHS	G4444H101
TCRX	TSCAN THERAPEUTICS INC	1,016,375	$5.062M	1.5%	$7.74	-22.0%	COM	89854M101
—	UNICYCIVE THERAPEUTICS INC	8,559,000	$3.491M	1.0%	$0.41	—	COM	90466Y103
—	PROMIS NEUROSCIENCES INC	2,790,698	$3.488M	1.0%	$1.25	—	COM NEW	74346M406
RNAC	CARTESIAN THERAPEUTICS INC	200,000	$3.224M	0.9%	$15.62	0.0%	COM NEW	816212302
VTGN	VISTAGEN THERAPEUTICS INC	674,075	$2.029M	0.6%	$3.78	-9.8%	COM	92840H400
CLYM	ELIEM THERAPEUTICS INC	248,168	$1.263M	0.4%	$7.07	0.0%	COM	28658R106