GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2024 (← Previous) (Next →)

Filing Date: Aug 14, 2024

Total Value: $522M (100.0% shares, 0.0% debt)

Holdings (33)

URGN UROGEN PHARMA LTD 9.3%

Value $48.77M Shares 2,906,259 Est. Cost $15.87 Unrealized -10.4%

NGNE NEUROGENE INC 7.0%

Value $36.55M Shares 1,004,291 Est. Cost $14.51 Unrealized +143.1%

ABVX ABIVAX SA 6.3%

Value $32.68M Shares 2,472,188 Est. Cost $12.06 Unrealized —

— MERUS N V 5.9%

Value $30.96M Shares 523,288 Est. Cost $52.47 Unrealized —

PLRX PLIANT THERAPEUTICS INC 5.4%

Value $28.35M Shares 2,636,864 Est. Cost $16.18 Unrealized -20.3%

ACLX ARCELLX INC 5.2%

Value $27.15M Shares 492,000 Est. Cost $56.99 Unrealized -4.6%

— DYNAVAX TECHNOLOGIES CORP 5.1%

Value $26.66M Shares 2,374,000 Est. Cost $11.86 Unrealized —

EOLS EVOLUS INC 5.1%

Value $26.6M Shares 2,451,772 Est. Cost $9.65 Unrealized +27.4%

CYTK CYTOKINETICS INC 4.9%

Value $25.69M Shares 474,202 Est. Cost $51.75 Unrealized +16.6%

DNTH DIANTHUS THERAPEUTICS INC 3.8%

Value $19.62M Shares 757,929 Est. Cost $22.14 Unrealized +8.6%

INSM INSMED INC 3.2%

Value $16.75M Shares 250,000 Est. Cost $26.50 Unrealized +46.4%

ZURA ZURA BIO LTD 3.1%

Value $16.25M Shares 4,642,241 Est. Cost $6.43 Unrealized -36.6%

KALV KALVISTA PHARMACEUTICALS INC 3.0%

Value $15.77M Shares 1,338,568 Est. Cost $11.67 Unrealized 0.0%

IONS IONIS PHARMACEUTICALS INC 3.0%

Value $15.73M Shares 330,000 Est. Cost $41.01 Unrealized 0.0%

CNTX CONTEXT THERAPEUTICS INC 2.8%

Value $14.88M Shares 7,419,355 Est. Cost $1.72 Unrealized 0.0%

FOLD AMICUS THERAPEUTICS INC 2.8%

Value $14.84M Shares 1,495,500 Est. Cost $12.08 Unrealized -15.0%

— OPTINOSE INC 2.7%

Value $14.28M Shares 13,727,097 Est. Cost $1.52 Unrealized —

ESPR ESPERION THERAPEUTICS INC NE 2.5%

Value $12.86M Shares 5,791,594 Est. Cost $2.43 Unrealized -3.2%

VYGR VOYAGER THERAPEUTICS INC 2.4%

Value $12.67M Shares 1,601,527 Est. Cost $7.91 Unrealized —

OTLK OUTLOOK THERAPEUTICS INC 2.4%

Value $12.56M Shares 1,701,510 Est. Cost $8.08 Unrealized -0.6%

AUTL AUTOLUS THERAPEUTICS PLC 2.3%

Value $11.98M Shares 3,441,667 Est. Cost $4.46 Unrealized —

JSPR JASPER THERAPEUTICS INC 1.7%

Value $9.126M Shares 402,015 Est. Cost $17.76 Unrealized +35.0%

OLMA OLEMA PHARMACEUTICALS INC 1.7%

Value $8.622M Shares 796,880 Est. Cost $10.84 Unrealized 0.0%

TERN TERNS PHARMACEUTICALS INC 1.5%

Value $7.827M Shares 1,149,406 Est. Cost $5.81 Unrealized +4.3%

VRDN VIRIDIAN THERAPEUTICS INC 1.2%

Value $6.505M Shares 500,000 Est. Cost $19.39 Unrealized -28.6%

TCRX TSCAN THERAPEUTICS INC 1.1%

Value $5.504M Shares 940,831 Est. Cost $7.88 Unrealized 0.0%

VTGN VISTAGEN THERAPEUTICS INC 1.0%

Value $5.322M Shares 1,529,338 Est. Cost $3.78 Unrealized +14.4%

BBOT HELIX ACQUISITION CORP II 1.0%

Value $5.11M Shares 500,000 Est. Cost $10.35 Unrealized -0.6%

PBYI PUMA BIOTECHNOLOGY INC 0.9%

Value $4.846M Shares 1,486,544 Est. Cost $3.77 Unrealized +16.6%

KYTX KYVERNA THERAPEUTICS INC 0.7%

Value $3.744M Shares 499,152 Est. Cost $19.05 Unrealized -19.8%

SYRE SPYRE THERAPEUTICS INC 0.6%

Value $3.165M Shares 134,612 Est. Cost $15.20 Unrealized +121.9%

ANAB ANAPTYSBIO INC 0.1%

Value $627K Shares 25,000 Est. Cost $23.39 Unrealized -0.5%

LXRX LEXICON PHARMACEUTICALS INC 0.0%

Value $50,400 Shares 30,000 Est. Cost $1.79 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
URGN	UROGEN PHARMA LTD	2,906,259	$48.77M	9.3%	$15.87	-10.4%	COM	M96088105
NGNE	NEUROGENE INC	1,004,291	$36.55M	7.0%	$14.51	+143.1%	COM	64135M105
ABVX	ABIVAX SA	2,472,188	$32.68M	6.3%	$12.06	—	SPONSORED ADS	00370M103
—	MERUS N V	523,288	$30.96M	5.9%	$52.47	—	COM	N5749R100
PLRX	PLIANT THERAPEUTICS INC	2,636,864	$28.35M	5.4%	$16.18	-20.3%	COM	729139105
ACLX	ARCELLX INC	492,000	$27.15M	5.2%	$56.99	-4.6%	COMMON STOCK	03940C100
—	DYNAVAX TECHNOLOGIES CORP	2,374,000	$26.66M	5.1%	$11.86	—	COM NEW	268158201
EOLS	EVOLUS INC	2,451,772	$26.6M	5.1%	$9.65	+27.4%	COM	30052C107
CYTK	CYTOKINETICS INC	474,202	$25.69M	4.9%	$51.75	+16.6%	COM NEW	23282W605
DNTH	DIANTHUS THERAPEUTICS INC	757,929	$19.62M	3.8%	$22.14	+8.6%	COM	252828108
INSM	INSMED INC	250,000	$16.75M	3.2%	$26.50	+46.4%	COM PAR $.01	457669307
ZURA	ZURA BIO LTD	4,642,241	$16.25M	3.1%	$6.43	-36.6%	CLASS A ORD SHS	G9TY5A101
KALV	KALVISTA PHARMACEUTICALS INC	1,338,568	$15.77M	3.0%	$11.67	0.0%	COM	483497103
IONS	IONIS PHARMACEUTICALS INC	330,000	$15.73M	3.0%	$41.01	0.0%	COM	462222100
CNTX	CONTEXT THERAPEUTICS INC	7,419,355	$14.88M	2.8%	$1.72	0.0%	COM	21077P108
FOLD	AMICUS THERAPEUTICS INC	1,495,500	$14.84M	2.8%	$12.08	-15.0%	COM	03152W109
—	OPTINOSE INC	13,727,097	$14.28M	2.7%	$1.52	—	COM	68404V100
ESPR	ESPERION THERAPEUTICS INC NE	5,791,594	$12.86M	2.5%	$2.43	-3.2%	COM	29664W105
VYGR	VOYAGER THERAPEUTICS INC	1,601,527	$12.67M	2.4%	$7.91	—	COM	92915B106
OTLK	OUTLOOK THERAPEUTICS INC	1,701,510	$12.56M	2.4%	$8.08	-0.6%	COM	69012T305
AUTL	AUTOLUS THERAPEUTICS PLC	3,441,667	$11.98M	2.3%	$4.46	—	SPON ADS	05280R100
JSPR	JASPER THERAPEUTICS INC	402,015	$9.126M	1.7%	$17.76	+35.0%	COM NEW	471871202
OLMA	OLEMA PHARMACEUTICALS INC	796,880	$8.622M	1.7%	$10.84	0.0%	COM	68062P106
TERN	TERNS PHARMACEUTICALS INC	1,149,406	$7.827M	1.5%	$5.81	+4.3%	COM	880881107
VRDN	VIRIDIAN THERAPEUTICS INC	500,000	$6.505M	1.2%	$19.39	-28.6%	COM	92790C104
TCRX	TSCAN THERAPEUTICS INC	940,831	$5.504M	1.1%	$7.88	0.0%	COM	89854M101
VTGN	VISTAGEN THERAPEUTICS INC	1,529,338	$5.322M	1.0%	$3.78	+14.4%	COM	92840H400
BBOT	HELIX ACQUISITION CORP II	500,000	$5.11M	1.0%	$10.35	-0.6%	CL A ORD SHS	G4444H101
PBYI	PUMA BIOTECHNOLOGY INC	1,486,544	$4.846M	0.9%	$3.77	+16.6%	COM	74587V107
KYTX	KYVERNA THERAPEUTICS INC	499,152	$3.744M	0.7%	$19.05	-19.8%	COM	501976104
SYRE	SPYRE THERAPEUTICS INC	134,612	$3.165M	0.6%	$15.20	+121.9%	COM NEW	00773J202
ANAB	ANAPTYSBIO INC	25,000	$627K	0.1%	$23.39	-0.5%	COM	032724106
LXRX	LEXICON PHARMACEUTICALS INC	30,000	$50,400	0.0%	$1.79	0.0%	COM NEW	528872302