Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q2 2025 (← Previous) (Next →)
Filing Date: Aug 14, 2025
Total Value: $1.605B (99.7% shares, 0.3% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ARGX | ARGENX SE | 175,750 | $96.88M | 6.0% | $160.49 | — | SPONSORED ADR | 04016X101 |
| LLY | ELI LILLY & CO | 116,500 | $90.82M | 5.7% | $683.47 | +13.2% | COM | 532457108 |
| — | MERUS N V | 1,063,608 | $55.95M | 3.5% | $32.74 | — | COM | N5749R100 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 861,153 | $54.42M | 3.4% | $17.22 | +255.6% | COM | 76243J105 |
| INSM | INSMED INC | 525,000 | $52.84M | 3.3% | $39.44 | +93.9% | COM PAR $.01 | 457669307 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,391,072 | $50.58M | 3.2% | $58.22 | -38.1% | COM | 90400D108 |
| RVMD | REVOLUTION MEDICINES INC | 1,330,960 | $48.97M | 3.1% | $31.87 | +20.5% | COM | 76155X100 |
| ISRG | INTUITIVE SURGICAL INC | 82,000 | $44.56M | 2.8% | $264.69 | +97.5% | COM NEW | 46120E602 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 140,296 | $42.46M | 2.6% | $118.06 | +152.4% | COM | 558868105 |
| MIRM | MIRUM PHARMACEUTICALS INC | 818,206 | $41.64M | 2.6% | $14.67 | +203.6% | COM | 604749101 |
| BSX | BOSTON SCIENTIFIC CORP | 355,000 | $38.13M | 2.4% | $63.16 | +60.2% | COM | 101137107 |
| ASND | ASCENDIS PHARMA A/S | 217,000 | $37.45M | 2.3% | $92.14 | — | SPONSORED ADR | 04351P101 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 242,500 | $37.34M | 2.3% | $74.37 | +73.8% | COM | 450056106 |
| — | AKERO THERAPEUTICS INC | 640,526 | $34.18M | 2.1% | $29.53 | — | COM | 00973Y108 |
| PEN | PENUMBRA INC | 128,500 | $32.98M | 2.1% | $179.03 | +52.0% | COM | 70975L107 |
| AGIO | AGIOS PHARMACEUTICALS INC | 989,745 | $32.92M | 2.1% | $33.80 | -10.3% | COM | 00847X104 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 100,000 | $32.61M | 2.0% | $107.54 | +157.3% | COM | 02043Q107 |
| EVH | EVOLENT HEALTH INC | 2,820,700 | $31.76M | 2.0% | $20.99 | -56.3% | CL A | 30050B101 |
| ZLAB | ZAI LAB LTD | 871,392 | $30.47M | 1.9% | $51.35 | — | ADR | 98887Q104 |
| EXAS | EXACT SCIENCES CORP | 572,000 | $30.4M | 1.9% | $53.81 | -5.6% | COM | 30063P105 |
| XENE | XENON PHARMACEUTICALS INC | 931,681 | $29.16M | 1.8% | $24.19 | +34.8% | COM | 98420N105 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,908,208 | $28.24M | 1.8% | $13.21 | +25.4% | COM | 89422G107 |
| SRRK | SCHOLAR ROCK HLDG CORP | 794,133 | $28.13M | 1.8% | $32.85 | -4.4% | COM | 80706P103 |
| DXCM | DEXCOM INC | 286,750 | $25.03M | 1.6% | $94.97 | -17.5% | COM | 252131107 |
| PHR | PHREESIA INC | 837,300 | $23.83M | 1.5% | $25.92 | -2.1% | COM | 71944F106 |
| — | BLUEPRINT MEDICINES CORP | 185,500 | $23.78M | 1.5% | $70.25 | — | COM | 09627Y109 |
| GPCR | STRUCTURE THERAPEUTICS INC | 1,135,879 | $23.56M | 1.5% | $39.12 | — | SPONSORED ADS | 86366E106 |
| THC | TENET HEALTHCARE CORP | 130,000 | $22.88M | 1.4% | $148.69 | +1.2% | COM NEW | 88033G407 |
| CAI | CARIS LIFE SCIENCES INC | 793,651 | $21.21M | 1.3% | $26.95 | 0.0% | COM | 142152107 |
| KYMR | KYMERA THERAPEUTICS INC | 450,374 | $19.65M | 1.2% | $30.84 | +11.7% | COM | 501575104 |
| OMDA | OMADA HEALTH INC | 919,951 | $16.84M | 1.0% | $17.31 | 0.0% | COM | 68170A108 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 812,653 | $16.54M | 1.0% | $32.64 | -40.4% | COM NEW | 15117B202 |
| AZTA | AZENTA INC | 530,400 | $16.33M | 1.0% | $58.22 | -51.7% | COM | 114340102 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 696,000 | $15.79M | 1.0% | $53.71 | -55.9% | COM | 00404A109 |
| UNH | UNITEDHEALTH GROUP INC | 50,500 | $15.75M | 1.0% | $279.63 | +34.1% | COM | 91324P102 |
| TARS | TARSUS PHARMACEUTICALS INC | 373,750 | $15.14M | 0.9% | $48.01 | -6.3% | COM | 87650L103 |
| SMMT | SUMMIT THERAPEUTICS INC | 710,000 | $15.11M | 0.9% | $14.06 | +62.2% | COM | 86627T108 |
| AGL | AGILON HEALTH INC | 6,550,400 | $15.07M | 0.9% | $31.45 | -89.8% | COM | 00857U107 |
| OSCR | OSCAR HEALTH INC | 700,000 | $15.01M | 0.9% | $11.50 | +29.2% | CL A | 687793109 |
| VERA | VERA THERAPEUTICS INC | 617,396 | $14.55M | 0.9% | $35.12 | -36.0% | CL A | 92337R101 |
| ELVN | ENLIVEN THERAPEUTICS INC | 701,408 | $14.07M | 0.9% | $16.88 | +12.2% | COM | 29337E102 |
| INSP | INSPIRE MED SYS INC | 107,500 | $13.95M | 0.9% | $196.68 | -26.3% | COM | 457730109 |
| SLNO | SOLENO THERAPEUTICS INC | 154,528 | $12.95M | 0.8% | $56.35 | +32.8% | COM | 834203309 |
| CMPX | COMPASS THERAPEUTICS INC | 4,962,955 | $12.9M | 0.8% | $3.23 | -36.1% | COM | 20454B104 |
| XBI | SPDR SERIES TRUST | 151,750 | $12.58M | 0.8% | $82.93 | — | S&P BIOTECH | 78464A870 |
| ACLX | ARCELLX INC | 186,314 | $12.27M | 0.8% | $62.26 | 0.0% | COMMON STOCK | 03940C100 |
| MREO | MEREO BIOPHARMA GROUP PLC | 4,465,292 | $12.1M | 0.8% | $2.75 | — | SPON ADS | 589492107 |
| DHR | DANAHER CORPORATION | 59,000 | $11.65M | 0.7% | $216.97 | -11.0% | COM | 235851102 |
| FOLD | AMICUS THERAPEUTICS INC | 1,960,334 | $11.23M | 0.7% | $10.81 | -40.3% | COM | 03152W109 |
| WST | WEST PHARMACEUTICAL SVSC INC | 51,030 | $11.17M | 0.7% | $299.09 | -28.7% | COM | 955306105 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 88,800 | $11.16M | 0.7% | $78.19 | +46.7% | COM | 64125C109 |
| PHVS | PHARVARIS N V | 623,402 | $10.97M | 0.7% | $26.42 | -39.0% | COM | N69605108 |
| EW | EDWARDS LIFESCIENCES CORP | 131,000 | $10.25M | 0.6% | $63.05 | +18.3% | COM | 28176E108 |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 536,111 | $9.709M | 0.6% | $19.43 | -6.1% | ORDINARY SHARES | N62509109 |
| ARDX | ARDELYX INC | 2,286,273 | $8.962M | 0.6% | $5.10 | -19.1% | COM | 039697107 |
| NUVL | NUVALENT INC | 93,328 | $7.121M | 0.4% | $78.38 | -6.6% | COM | 670703107 |
| ACRS | ACLARIS THERAPEUTICS INC | 4,769,309 | $6.772M | 0.4% | $6.19 | -78.2% | COM | 00461U105 |
| — | CIDARA THERAPEUTICS INC | 134,133 | $6.534M | 0.4% | $48.71 | — | COM NEW | 171757206 |
| ZBIO | ZENAS BIOPHARMA INC | 640,467 | $6.206M | 0.4% | $17.98 | -45.8% | COM | 98937L105 |
| REGN | REGENERON PHARMACEUTICALS | 11,300 | $5.933M | 0.4% | $587.92 | -5.4% | COM | 75886F107 |
| COGT | COGENT BIOSCIENCES INC | 800,199 | $5.745M | 0.4% | $5.54 | 0.0% | COM | 19240Q201 |
| DYN | DYNE THERAPEUTICS INC | 580,998 | $5.531M | 0.3% | $21.04 | -47.7% | COM | 26818M108 |
| CGEM | CULLINAN THERAPEUTICS INC | 668,233 | $5.032M | 0.3% | $20.46 | -60.7% | COM | 230031106 |
| — | GOSSAMER BIO INC | 9,573,000 | $4.952M | 0.3% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| JANX | JANUX THERAPEUTICS INC | 210,266 | $4.857M | 0.3% | $52.16 | -49.5% | COM | 47103J105 |
| MLYS | MINERALYS THERAPEUTICS INC | 324,513 | $4.391M | 0.3% | $11.54 | +25.6% | COM | 603170101 |
| TMO | THERMO FISHER SCIENTIFIC INC | 10,000 | $4.055M | 0.3% | $417.06 | 0.0% | COM | 883556102 |
| GOSS | GOSSAMER BIO INC | 3,266,960 | $4.018M | 0.3% | $2.62 | -58.3% | COM | 38341P102 |
| IMVT | IMMUNOVANT INC | 221,500 | $3.544M | 0.2% | $28.27 | -46.5% | COM | 45258J102 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 499,764 | $3.203M | 0.2% | $3.97 | +22.6% | COM | 03237H101 |
| BCAX | BICARA THERAPEUTICS INC | 336,070 | $3.122M | 0.2% | $25.50 | -53.3% | COM | 055477103 |
| JSPR | JASPER THERAPEUTICS INC | 545,171 | $3.026M | 0.2% | $16.31 | -69.8% | COM NEW | 471871202 |
| PRTA | PROTHENA CORP PLC | 492,601 | $2.99M | 0.2% | $17.57 | -57.3% | SHS | G72800108 |
| ATEC | ALPHATEC HLDGS INC | 267,500 | $2.969M | 0.2% | $8.68 | +32.4% | COM NEW | 02081G201 |
| LENZ | LENZ THERAPEUTICS INC | 83,982 | $2.462M | 0.2% | $26.70 | +1.9% | COM | 52635N103 |
| EDAP | EDAP TMS S A | 1,270,000 | $2.095M | 0.1% | $7.23 | — | SPONSORED ADR | 268311107 |
| CGEN | COMPUGEN LTD | 989,990 | $1.762M | 0.1% | $6.12 | -75.8% | ORD | M25722105 |
| SION | SIONNA THERAPEUTICS INC | 99,429 | $1.725M | 0.1% | $16.34 | -19.8% | COM | 829401108 |
| LUNG | PULMONX CORP | 651,100 | $1.686M | 0.1% | $31.32 | -87.4% | COM | 745848101 |
| NGNE | NEUROGENE INC | 104,339 | $1.56M | 0.1% | $35.51 | -55.8% | COM | 64135M105 |
| CATX | PERSPECTIVE THERAPEUTICS INC | 444,383 | $1.529M | 0.1% | $14.00 | -81.1% | COM NEW | 46489V302 |
| APLS | APELLIS PHARMACEUTICALS INC | 84,300 | $1.459M | 0.1% | $43.92 | -57.9% | COM | 03753U106 |
| SRPT | SAREPTA THERAPEUTICS INC | 68,600 | $1.173M | 0.1% | $68.51 | -37.7% | COM | 803607100 |
| — | MERSANA THERAPEUTICS INC | 3,814,684 | $1.129M | 0.1% | $10.59 | — | COM | 59045L106 |
| — | APPLIED THERAPEUTICS INC | 2,075,991 | $646K | 0.0% | $12.37 | — | COM | 03828A101 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,483,468 | $595K | 0.0% | $6.95 | — | SPONDS ADS | 00653A107 |
| KRRO | KORRO BIO INC | 35,719 | $446K | 0.0% | $55.25 | -73.9% | COM | 500946108 |
| CRL | CHARLES RIV LABS INTL INC | 2,700 | $410K | 0.0% | $133.35 | 0.0% | COM | 159864107 |
| — | 89BIO INC | 40,000 | $393K | 0.0% | $7.63 | — | COM | 282559103 |
| PCVX | VAXCYTE INC | 11,100 | $361K | 0.0% | $32.78 | 0.0% | COM | 92243G108 |
| NVAX | NOVAVAX INC | 53,900 | $340K | 0.0% | $31.79 | -79.2% | COM NEW | 670002401 |
| TLPH | TALPHERA INC | 316,460 | $146K | 0.0% | $2.81 | -82.3% | COM NEW | 00444T209 |
| — | NUVATION BIO INC | 134,028 | $36,174 | 0.0% | $2.67 | — | *W EXP 02/10/202 | 67080N119 |