Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value ($000): $695,014 (100.0% shares, 0.0% debt)

Holdings (36)

APLS APELLIS PHARMACEUTICALS INC 30.8%

Value ($000) $214,370 Shares 3,250,000 Est. Cost $48.31 Unrealized +19.4%

— CHINOOK THERAPEUTICS INC 8.5%

Value ($000) $59,072 Shares 2,551,703 Est. Cost $16.88 Unrealized —

— VERONA PHARMA PLC 7.1%

Value ($000) $49,557 Shares 2,468,000 Est. Cost $17.59 Unrealized —

— CYMABAY THERAPEUTICS INC 5.7%

Value ($000) $39,858 Shares 4,570,918 Est. Cost $7.72 Unrealized —

RCUS ARCUS BIOSCIENCES INC 5.7%

Value ($000) $39,617 Shares 2,172,000 Est. Cost $33.27 Unrealized -42.6%

VRDN VIRIDIAN THERAPEUTICS INC 4.3%

Value ($000) $30,146 Shares 1,185,000 Est. Cost $25.79 Unrealized +24.3%

ROIV ROIVANT SCIENCES LTD 4.1%

Value ($000) $28,812 Shares 3,904,000 Est. Cost $8.23 Unrealized 0.0%

— MIRATI THERAPEUTICS INC 4.0%

Value ($000) $27,885 Shares 750,000 Est. Cost $52.54 Unrealized —

CLDX CELLDEX THERAPEUTICS INC NEW 3.9%

Value ($000) $27,341 Shares 759,898 Est. Cost $25.60 Unrealized +68.6%

BBIO BRIDGEBIO PHARMA INC 3.2%

Value ($000) $22,187 Shares 1,338,160 Est. Cost $30.51 Unrealized -61.8%

TNDM TANDEM DIABETES CARE INC 2.8%

Value ($000) $19,287 Shares 474,929 Est. Cost $54.82 Unrealized -24.5%

— AEROVATE THERAPEUTICS INC 1.8%

Value ($000) $12,540 Shares 621,712 Est. Cost $29.30 Unrealized —

— JASPER THERAPEUTICS INC 1.7%

Value ($000) $11,552 Shares 6,382,500 Est. Cost $1.81 Unrealized —

TVTX TRAVERE THERAPEUTICS INC 1.6%

Value ($000) $11,133 Shares 495,000 Est. Cost $21.26 Unrealized 0.0%

— ALPINE IMMUNE SCIENCES INC 1.3%

Value ($000) $9,279 Shares 1,202,000 Est. Cost $7.20 Unrealized —

FDMT 4D MOLECULAR THERAPEUTICS IN 1.2%

Value ($000) $8,595 Shares 499,996 Est. Cost $30.23 Unrealized -35.7%

— ITEOS THERAPEUTICS INC 1.2%

Value ($000) $8,112 Shares 596,000 Est. Cost $18.03 Unrealized —

DYN DYNE THERAPEUTICS INC 1.1%

Value ($000) $7,983 Shares 692,945 Est. Cost $12.99 Unrealized 0.0%

XLO XILIO THERAPEUTICS INC 1.1%

Value ($000) $7,687 Shares 2,425,000 Est. Cost $2.77 Unrealized +13.1%

VKTX VIKING THERAPEUTICS INC 0.9%

Value ($000) $6,244 Shares 375,000 Est. Cost $4.46 Unrealized +131.4%

VERA VERA THERAPEUTICS INC 0.9%

Value ($000) $6,169 Shares 795,000 Est. Cost $14.69 Unrealized -47.4%

— 89BIO INC 0.9%

Value ($000) $6,092 Shares 400,000 Est. Cost $12.86 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 0.8%

Value ($000) $5,864 Shares 382,000 Est. Cost $26.66 Unrealized -17.5%

— INTRA-CELLULAR THERAPIES INC 0.7%

Value ($000) $5,128 Shares 94,700 Est. Cost $46.53 Unrealized —

GERN GERON CORP 0.7%

Value ($000) $4,943 Shares 2,278,000 Est. Cost $2.84 Unrealized 0.0%

ACRS ACLARIS THERAPEUTICS INC 0.7%

Value ($000) $4,668 Shares 577,000 Est. Cost $12.69 Unrealized 0.0%

ANNX ANNEXON INC 0.7%

Value ($000) $4,582 Shares 1,190,000 Est. Cost $5.50 Unrealized 0.0%

— GLYCOMIMETICS INC 0.5%

Value ($000) $3,780 Shares 3,000,000 Est. Cost $1.26 Unrealized —

— RENEO PHARMACEUTICALS INC 0.4%

Value ($000) $2,512 Shares 420,000 Est. Cost $5.98 Unrealized —

GOSS GOSSAMER BIO INC 0.4%

Value ($000) $2,467 Shares 1,958,069 Est. Cost $9.60 Unrealized -80.1%

GPCR STRUCTURE THERAPEUTICS INC 0.3%

Value ($000) $2,229 Shares 93,692 Est. Cost $23.79 Unrealized —

BBIO BRIDGEBIO PHARMA INC 0.2%

Value ($000) $1,658 Shares 100,000 Est. Cost $30.51 Unrealized -61.8%

STOK STOKE THERAPEUTICS INC 0.2%

Value ($000) $1,547 Shares 185,669 Est. Cost $27.91 Unrealized -67.7%

CNTA CENTESSA PHARMACEUTICALS PLC 0.2%

Value ($000) $1,525 Shares 396,000 Est. Cost $3.85 Unrealized —

— VECTIVBIO HLDG AG 0.0%

Value ($000) $300 Shares 35,259 Est. Cost $8.51 Unrealized —

— PIERIS PHARMACEUTICALS INC 0.0%

Value ($000) $294 Shares 301,490 Est. Cost $0.98 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	3,250,000	$214,370	30.8%	$48.31	+19.4%	COM	03753U106
—	CHINOOK THERAPEUTICS INC	2,551,703	$59,072	8.5%	$16.88	—	COM	16961L106
—	VERONA PHARMA PLC	2,468,000	$49,557	7.1%	$17.59	—	SPONSORED ADS	925050106
—	CYMABAY THERAPEUTICS INC	4,570,918	$39,858	5.7%	$7.72	—	COM	23257D103
RCUS	ARCUS BIOSCIENCES INC	2,172,000	$39,617	5.7%	$33.27	-42.6%	COM	03969F109
VRDN	VIRIDIAN THERAPEUTICS INC	1,185,000	$30,146	4.3%	$25.79	+24.3%	COM	92790C104
ROIV	ROIVANT SCIENCES LTD	3,904,000	$28,812	4.1%	$8.23	0.0%	SHS	G76279101
—	MIRATI THERAPEUTICS INC	750,000	$27,885	4.0%	$52.54	—	COM	60468T105
CLDX	CELLDEX THERAPEUTICS INC NEW	759,898	$27,341	3.9%	$25.60	+68.6%	COM NEW	15117B202
BBIO	BRIDGEBIO PHARMA INC	1,338,160	$22,187	3.2%	$30.51	-61.8%	COM	10806X102
TNDM	TANDEM DIABETES CARE INC	474,929	$19,287	2.8%	$54.82	-24.5%	COM NEW	875372203
—	AEROVATE THERAPEUTICS INC	621,712	$12,540	1.8%	$29.30	—	COM	008064107
—	JASPER THERAPEUTICS INC	6,382,500	$11,552	1.7%	$1.81	—	COM	471871103
TVTX	TRAVERE THERAPEUTICS INC	495,000	$11,133	1.6%	$21.26	0.0%	COM	89422G107
—	ALPINE IMMUNE SCIENCES INC	1,202,000	$9,279	1.3%	$7.20	—	COM	02083G100
FDMT	4D MOLECULAR THERAPEUTICS IN	499,996	$8,595	1.2%	$30.23	-35.7%	COM	35104E100
—	ITEOS THERAPEUTICS INC	596,000	$8,112	1.2%	$18.03	—	COM	46565G104
DYN	DYNE THERAPEUTICS INC	692,945	$7,983	1.1%	$12.99	0.0%	COM	26818M108
XLO	XILIO THERAPEUTICS INC	2,425,000	$7,687	1.1%	$2.77	+13.1%	COM	98422T100
VKTX	VIKING THERAPEUTICS INC	375,000	$6,244	0.9%	$4.46	+131.4%	COM	92686J106
VERA	VERA THERAPEUTICS INC	795,000	$6,169	0.9%	$14.69	-47.4%	CL A	92337R101
—	89BIO INC	400,000	$6,092	0.9%	$12.86	—	COM	282559103
RNAM	AVIDITY BIOSCIENCES INC	382,000	$5,864	0.8%	$26.66	-17.5%	COM	05370A108
—	INTRA-CELLULAR THERAPIES INC	94,700	$5,128	0.7%	$46.53	—	COM	46116X101
GERN	GERON CORP	2,278,000	$4,943	0.7%	$2.84	0.0%	COM	374163103
ACRS	ACLARIS THERAPEUTICS INC	577,000	$4,668	0.7%	$12.69	0.0%	COM	00461U105
ANNX	ANNEXON INC	1,190,000	$4,582	0.7%	$5.50	0.0%	COM	03589W102
—	GLYCOMIMETICS INC	3,000,000	$3,780	0.5%	$1.26	—	COM	38000Q102
—	RENEO PHARMACEUTICALS INC	420,000	$2,512	0.4%	$5.98	—	COM	75974E103
GOSS	GOSSAMER BIO INC	1,958,069	$2,467	0.4%	$9.60	-80.1%	COM	38341P102
GPCR	STRUCTURE THERAPEUTICS INC	93,692	$2,229	0.3%	$23.79	—	SPONSORED ADS	86366E106
BBIO	BRIDGEBIO PHARMA INC	100,000	$1,658	0.2%	$30.51	-61.8%	Call	10806X102
STOK	STOKE THERAPEUTICS INC	185,669	$1,547	0.2%	$27.91	-67.7%	COM	86150R107
CNTA	CENTESSA PHARMACEUTICALS PLC	396,000	$1,525	0.2%	$3.85	—	SPONSORED ADS	152309100
—	VECTIVBIO HLDG AG	35,259	$300	0.0%	$8.51	—	ORD SHS	H9060V101
—	PIERIS PHARMACEUTICALS INC	301,490	$294	0.0%	$0.98	—	COM	720795103