DAFNA Capital Management LLC Diversified Active

Location: Los Angeles, CA

CIK: 0001389933 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value: $362M (98.6% shares, 1.4% debt)

Holdings (76)

XBI SPDR S&P BIOTECH ETF 9.5%
Value $34.46M Shares 415,505 Est. Cost $81.52 Unrealized
STXS STEREOTAXIS INC 8.0%
Value $29M Shares 13,680,554 Est. Cost $0.97 Unrealized +110.3%
RVMD REVOLUTION MEDICINES INC 6.9%
Value $24.91M Shares 677,176 Est. Cost $33.32 Unrealized +15.3%
BLUEPRINT MEDICINES CORP 6.0%
Value $21.63M Shares 168,763 Est. Cost $72.74 Unrealized
MERUS BV 5.8%
Value $20.98M Shares 398,804 Est. Cost $28.88 Unrealized
ATRC ATRICURE INC 5.4%
Value $19.41M Shares 592,273 Est. Cost $25.94 Unrealized +25.3%
CYTK CYTOKINETICS INC 3.6%
Value $13.15M Shares 398,100 Est. Cost $34.56 Unrealized +0.7%
IDYA IDEAYA BIOSCIENCES INC 3.6%
Value $13.01M Shares 619,090 Est. Cost $19.18 Unrealized +0.0%
IBB ISHARES NASDAQ BIOTECH INDX 3.6%
Value $12.97M Shares 102,500 Est. Cost $126.22 Unrealized
ASND ASCENDIS PHARMA A/S 3.5%
Value $12.54M Shares 72,677 Est. Cost $109.10 Unrealized
XENE XENON PHARMACEUTICALS INC 2.5%
Value $9.012M Shares 287,939 Est. Cost $14.21 Unrealized +129.5%
NBIX NEUROCRINE BIOSCIENCES INC 2.5%
Value $8.876M Shares 70,615 Est. Cost $81.16 Unrealized +41.3%
AXGN AXOGEN INC 2.2%
Value $8.048M Shares 741,782 Est. Cost $9.08 Unrealized +44.2%
KALV KALVISTA PHARMACEUTICALS INC 1.8%
Value $6.577M Shares 581,757 Est. Cost $11.48 Unrealized +6.5%
DXCM DEXCOM INC 1.6%
Value $5.722M Shares 65,552 Est. Cost $72.93 Unrealized +7.5%
DAWN DAY ONE BIOPHARMACEUTICALS I 1.6%
Value $5.715M Shares 879,163 Est. Cost $12.03 Unrealized -42.8%
STOK STOKE THERAPEUTICS INC 1.6%
Value $5.697M Shares 501,972 Est. Cost $8.99 Unrealized +5.6%
TNDM TANDEM DIABETES CARE INC 1.5%
Value $5.484M Shares 294,208 Est. Cost $29.63 Unrealized -33.2%
RCUS ARCUS BIOSCIENCES INC 1.4%
Value $5.109M Shares 627,626 Est. Cost $16.20 Unrealized -47.3%
SNDX SYNDAX PHARMACEUTICALS INC 1.4%
Value $5.091M Shares 543,602 Est. Cost $17.82 Unrealized -38.2%
MLYS MINERALYS THERAPEUTICS INC 1.4%
Value $5.027M Shares 371,523 Est. Cost $12.15 Unrealized +19.2%
ASCENDIS PHARMA A/S 1.4%
Value $5.01M Shares 4,000,000 Est. Cost $0.91 Unrealized
URGN UROGEN PHARMA LTD 1.3%
Value $4.788M Shares 349,515 Est. Cost $14.07 Unrealized -31.8%
INGN INOGEN INC 1.2%
Value $4.258M Shares 605,625 Est. Cost $10.19 Unrealized -34.0%
GLPG GALAPAGOS NV 1.0%
Value $3.644M Shares 130,175 Est. Cost $55.30 Unrealized
BHVN BIOHAVEN LTD 0.9%
Value $3.319M Shares 235,235 Est. Cost $34.08 Unrealized -47.7%
PRQR PROQR THERAPEUTICS N V 0.9%
Value $3.198M Shares 1,567,561 Est. Cost $3.11 Unrealized -47.6%
EWTX EDGEWISE THERAPEUTICS INC 0.9%
Value $3.122M Shares 238,140 Est. Cost $11.22 Unrealized +28.5%
PODD INSULET CORP 0.9%
Value $3.11M Shares 9,900 Est. Cost $186.49 Unrealized +54.8%
IMVT IMMUNOVANT INC 0.8%
Value $3.064M Shares 191,493 Est. Cost $24.59 Unrealized -38.5%
ALKS ALKERMES PLC 0.8%
Value $2.968M Shares 103,748 Est. Cost $25.01 Unrealized +19.0%
BCAX BICARA THERAPEUTICS INC 0.8%
Value $2.945M Shares 317,001 Est. Cost $15.33 Unrealized -22.3%
TELA TELA BIO INC 0.8%
Value $2.796M Shares 1,441,029 Est. Cost $2.81 Unrealized -53.4%
KURA KURA ONCOLOGY INC 0.7%
Value $2.674M Shares 463,368 Est. Cost $13.09 Unrealized -53.2%
DNLI DENALI THERAPEUTICS INC 0.7%
Value $2.357M Shares 168,500 Est. Cost $17.93 Unrealized -21.5%
CMPS COMPASS PATHWAYS PLC 0.6%
Value $2.271M Shares 811,046 Est. Cost $4.27 Unrealized
ALGN ALIGN TECHNOLOGY INC 0.6%
Value $2.083M Shares 11,000 Est. Cost $209.84 Unrealized -15.8%
BCRX BIOCRYST PHARMACEUTICALS INC 0.5%
Value $1.956M Shares 218,255 Est. Cost $10.00 Unrealized -6.8%
ASTRIA THERAPEUTICS INC 0.5%
Value $1.741M Shares 324,775 Est. Cost $8.44 Unrealized
KROS KEROS THERAPEUTICS INC 0.5%
Value $1.74M Shares 130,316 Est. Cost $46.06 Unrealized -70.7%
VKTX VIKING THERAPEUTICS INC 0.5%
Value $1.71M Shares 64,516 Est. Cost $8.10 Unrealized +224.8%
ARAY ACCURAY INC 0.5%
Value $1.675M Shares 1,222,358 Est. Cost $3.02 Unrealized -51.0%
BWAY BRAINSWAY LTD 0.5%
Value $1.672M Shares 127,151 Est. Cost $4.74 Unrealized
ALLO ALLOGENE THERAPEUTICS INC 0.4%
Value $1.56M Shares 1,380,118 Est. Cost $2.68 Unrealized -50.5%
LXEO LEXEO THERAPEUTICS INC 0.4%
Value $1.52M Shares 378,083 Est. Cost $10.46 Unrealized -68.6%
FHTX FOGHORN THERAPEUTICS INC 0.4%
Value $1.412M Shares 300,452 Est. Cost $6.06 Unrealized -31.1%
ITEOS THERAPEUTICS INC 0.4%
Value $1.404M Shares 140,847 Est. Cost $18.46 Unrealized
ORIC ORIC PHARMACEUTICALS INC 0.4%
Value $1.373M Shares 135,271 Est. Cost $8.74 Unrealized -23.2%
CMPX COMPASS THERAPEUTICS INC 0.4%
Value $1.369M Shares 526,660 Est. Cost $2.06 Unrealized 0.0%
IMTX IMMATICS NV 0.4%
Value $1.318M Shares 245,000 Est. Cost $9.36 Unrealized -47.0%
ALEC ALECTOR INC 0.4%
Value $1.278M Shares 912,928 Est. Cost $11.94 Unrealized -89.5%
MDWD MEDIWOUND LTD 0.3%
Value $1.249M Shares 64,479 Est. Cost $10.64 Unrealized +77.1%
GPCR STRUCTURE THERAPEUTICS INC 0.3%
Value $1.224M Shares 59,000 Est. Cost $32.49 Unrealized
BDTX BLACK DIAMOND THERAPEUTICS I 0.3%
Value $1.168M Shares 471,000 Est. Cost $2.89 Unrealized -33.3%
LRMR LARIMAR THERAPEUTICS INC 0.3%
Value $1.073M Shares 371,434 Est. Cost $5.77 Unrealized -59.9%
VYNE VYNE THERAPEUTICS INC 0.3%
Value $1.05M Shares 636,103 Est. Cost $2.46 Unrealized -47.2%
GOSS GOSSAMER BIO INC 0.3%
Value $1.045M Shares 849,921 Est. Cost $1.15 Unrealized -5.4%
PVLA PALVELLA THERAPEUTICS INC 0.3%
Value $977K Shares 43,348 Est. Cost $15.71 Unrealized +49.4%
AUTL AUTOLUS THERAPEUTICS PLC 0.3%
Value $970K Shares 425,616 Est. Cost $3.25 Unrealized
IPSC CENTURY THERAPEUTICS INC 0.3%
Value $952K Shares 1,704,232 Est. Cost $6.77 Unrealized -92.1%
NGNE NEUROGENE INC 0.2%
Value $764K Shares 51,096 Est. Cost $36.92 Unrealized -57.5%
BNTX BIONTECH SE 0.2%
Value $745K Shares 7,000 Est. Cost $113.49 Unrealized
PYPD POLYPID LTD 0.2%
Value $734K Shares 207,900 Est. Cost $5.05 Unrealized -42.0%
KRRO KORRO BIO INC 0.2%
Value $721K Shares 57,691 Est. Cost $26.85 Unrealized -46.4%
CGEN COMPUGEN LTD 0.1%
Value $485K Shares 272,402 Est. Cost $4.18 Unrealized -64.5%
AQST AQUESTIVE THERAPEUTICS INC 0.1%
Value $470K Shares 142,000 Est. Cost $3.35 Unrealized -14.3%
BCYC BICYCLE THERAPEUTICS PLC 0.1%
Value $448K Shares 64,492 Est. Cost $27.77 Unrealized
ERAS ERASCA INC 0.1%
Value $445K Shares 350,000 Est. Cost $1.71 Unrealized -21.5%
ADICET BIO INC 0.1%
Value $329K Shares 540,000 Est. Cost $2.35 Unrealized
ADCT ADC THERAPEUTICS SA 0.1%
Value $327K Shares 122,081 Est. Cost $3.85 Unrealized -45.4%
SUTRO BIOPHARMA INC 0.1%
Value $312K Shares 437,079 Est. Cost $3.96 Unrealized
NKTR NEKTAR THERAPEUTICS 0.1%
Value $258K Shares 10,000 Est. Cost $11.24 Unrealized 0.0%
APRE APREA THERAPEUTICS INC 0.1%
Value $232K Shares 137,174 Est. Cost $6.22 Unrealized -72.6%
BIOMX INC 0.0%
Value $181K Shares 401,136 Est. Cost $1.02 Unrealized
PRCT PROCEPT BIOROBOTICS CORP 0.0%
Value $173K Shares 3,000 Est. Cost $56.54 Unrealized 0.0%
IFRX INFLARX NV 0.0%
Value $158K Shares 200,000 Est. Cost $1.89 Unrealized -37.3%