Prosight Management, LP Quant / Systematic

CIK: 0001617201 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value ($000): $428,779 (100.0% shares, 0.0% debt)

Holdings (42)

GLPG GALAPAGOS NV 9.3%

Value ($000) $39,836 Shares 1,150,000 Est. Cost $33.19 Unrealized —

MGTX MEIRAGTX HLDGS PLC 7.8%

Value ($000) $33,657 Shares 4,089,509 Est. Cost $6.93 Unrealized +14.0%

ADCT ADC THERAPEUTICS SA 7.0%

Value ($000) $29,889 Shares 7,472,303 Est. Cost $3.11 Unrealized +1.2%

KURA KURA ONCOLOGY INC 5.7%

Value ($000) $24,413 Shares 2,758,516 Est. Cost $9.51 Unrealized -25.0%

ISRG INTUITIVE SURGICAL INC 5.1%

Value ($000) $21,785 Shares 48,711 Est. Cost $479.87 Unrealized 0.0%

JANX JANUX THERAPEUTICS INC 4.9%

Value ($000) $21,149 Shares 865,350 Est. Cost $38.94 Unrealized -37.5%

ROIV ROIVANT SCIENCES LTD 4.7%

Value ($000) $20,206 Shares 1,335,500 Est. Cost $10.80 Unrealized +14.6%

ICLR ICON PLC 4.5%

Value ($000) $19,163 Shares 109,500 Est. Cost $194.71 Unrealized -14.0%

SNDX SYNDAX PHARMACEUTICALS INC 3.6%

Value ($000) $15,437 Shares 1,003,400 Est. Cost $16.38 Unrealized -20.1%

BBIO BRIDGEBIO PHARMA INC 3.2%

Value ($000) $13,738 Shares 264,500 Est. Cost $30.67 Unrealized +59.0%

CRNX CRINETICS PHARMACEUTICALS IN 3.2%

Value ($000) $13,690 Shares 328,684 Est. Cost $30.98 Unrealized +3.2%

FOLD AMICUS THERAPEUTICS INC 3.1%

Value ($000) $13,471 Shares 1,709,533 Est. Cost $7.87 Unrealized -9.5%

DXCM DEXCOM INC 3.1%

Value ($000) $13,136 Shares 195,217 Est. Cost $78.87 Unrealized +0.3%

STTK SHATTUCK LABS INC 3.0%

Value ($000) $13,028 Shares 5,451,195 Est. Cost $5.19 Unrealized -76.4%

ZYME ZYMEWORKS INC 3.0%

Value ($000) $12,803 Shares 749,611 Est. Cost $10.69 Unrealized +33.9%

CON CONCENTRA GROUP HOLDINGS PAR 3.0%

Value ($000) $12,767 Shares 610,000 Est. Cost $21.22 Unrealized +0.1%

— CORCEPT THERAPEUTICS INC 2.9%

Value ($000) $12,284 Shares 147,800 Est. Cost — Unrealized —

IMVT IMMUNOVANT INC 2.6%

Value ($000) $11,259 Shares 698,472 Est. Cost $23.65 Unrealized -31.5%

SEM SELECT MED HLDGS CORP 2.6%

Value ($000) $11,234 Shares 874,915 Est. Cost $14.11 Unrealized -6.3%

BHVN BIOHAVEN LTD 2.1%

Value ($000) $9,006 Shares 600,000 Est. Cost $20.40 Unrealized -28.6%

VRTX VERTEX PHARMACEUTICALS INC 1.9%

Value ($000) $8,029 Shares 20,500 Est. Cost $417.92 Unrealized 0.0%

BSX BOSTON SCIENTIFIC CORP 1.7%

Value ($000) $7,430 Shares 76,100 Est. Cost $103.56 Unrealized 0.0%

CDNA CAREDX INC 1.7%

Value ($000) $7,329 Shares 504,030 Est. Cost $17.83 Unrealized -20.0%

ACHC ACADIA HEALTHCARE COMPANY IN 1.4%

Value ($000) $6,190 Shares 250,000 Est. Cost $41.81 Unrealized -46.6%

TECX TECTONIC THERAPEUTIC INC 1.4%

Value ($000) $5,950 Shares 379,254 Est. Cost $31.39 Unrealized -34.2%

KIDS ORTHOPEDIATRICS CORP 1.3%

Value ($000) $5,720 Shares 308,707 Est. Cost $20.84 Unrealized -1.2%

CRBP CORBUS PHARMACEUTICALS HLDGS 1.0%

Value ($000) $4,344 Shares 343,400 Est. Cost $20.33 Unrealized -53.2%

RCKT ROCKET PHARMACEUTICALS INC 1.0%

Value ($000) $4,134 Shares 1,267,965 Est. Cost $13.68 Unrealized -77.0%

PRCT PROCEPT BIOROBOTICS CORP 0.6%

Value ($000) $2,748 Shares 76,991 Est. Cost $45.66 Unrealized 0.0%

ALGN ALIGN TECHNOLOGY INC 0.6%

Value ($000) $2,435 Shares 19,442 Est. Cost $156.63 Unrealized 0.0%

ARGX ARGENX SE 0.6%

Value ($000) $2,434 Shares 3,300 Est. Cost $576.53 Unrealized —

TWST TWIST BIOSCIENCE CORP 0.5%

Value ($000) $2,111 Shares 75,000 Est. Cost $30.29 Unrealized 0.0%

— AKERO THERAPEUTICS INC 0.4%

Value ($000) $1,855 Shares 39,072 Est. Cost $47.48 Unrealized —

CTMX CYTOMX THERAPEUTICS INC 0.4%

Value ($000) $1,802 Shares 564,800 Est. Cost $1.23 Unrealized +83.7%

SGHT SIGHT SCIENCES INC 0.4%

Value ($000) $1,513 Shares 439,941 Est. Cost $5.64 Unrealized -34.0%

OKUR ONKURE THERAPEUTICS INC 0.2%

Value ($000) $737 Shares 267,959 Est. Cost $6.29 Unrealized -60.6%

SDGR SCHRODINGER INC 0.2%

Value ($000) $699 Shares 34,830 Est. Cost $20.09 Unrealized 0.0%

RNTX REIN THERAPEUTICS INC 0.2%

Value ($000) $650 Shares 567,898 Est. Cost $2.99 Unrealized -57.5%

TBI TRUEBLUE INC 0.1%

Value ($000) $487 Shares 79,476 Est. Cost $6.33 Unrealized 0.0%

PRTA PROTHENA CORP PLC 0.0%

Value ($000) $195 Shares 20,000 Est. Cost $26.88 Unrealized -71.4%

PLRX PLIANT THERAPEUTICS INC 0.0%

Value ($000) $30 Shares 20,487 Est. Cost $3.27 Unrealized -53.4%

ACTU ACTUATE THERAPEUTICS ORD 0.0%

Value ($000) $6 Shares 885 Est. Cost $7.25 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
GLPG	GALAPAGOS NV	1,150,000	$39,836	9.3%	$33.19	—	SPON ADR	36315X101
MGTX	MEIRAGTX HLDGS PLC	4,089,509	$33,657	7.8%	$6.93	+14.0%	COM	G59665102
ADCT	ADC THERAPEUTICS SA	7,472,303	$29,889	7.0%	$3.11	+1.2%	SHS	H0036K147
KURA	KURA ONCOLOGY INC	2,758,516	$24,413	5.7%	$9.51	-25.0%	COM	50127T109
ISRG	INTUITIVE SURGICAL INC	48,711	$21,785	5.1%	$479.87	0.0%	COM NEW	46120E602
JANX	JANUX THERAPEUTICS INC	865,350	$21,149	4.9%	$38.94	-37.5%	COM	47103J105
ROIV	ROIVANT SCIENCES LTD	1,335,500	$20,206	4.7%	$10.80	+14.6%	SHS	G76279101
ICLR	ICON PLC	109,500	$19,163	4.5%	$194.71	-14.0%	SHS	G4705A100
SNDX	SYNDAX PHARMACEUTICALS INC	1,003,400	$15,437	3.6%	$16.38	-20.1%	COM	87164F105
BBIO	BRIDGEBIO PHARMA INC	264,500	$13,738	3.2%	$30.67	+59.0%	COM	10806X102
CRNX	CRINETICS PHARMACEUTICALS IN	328,684	$13,690	3.2%	$30.98	+3.2%	COM	22663K107
FOLD	AMICUS THERAPEUTICS INC	1,709,533	$13,471	3.1%	$7.87	-9.5%	COM	03152W109
DXCM	DEXCOM INC	195,217	$13,136	3.1%	$78.87	+0.3%	COM	252131107
STTK	SHATTUCK LABS INC	5,451,195	$13,028	3.0%	$5.19	-76.4%	COM	82024L103
ZYME	ZYMEWORKS INC	749,611	$12,803	3.0%	$10.69	+33.9%	COM	98985Y108
CON	CONCENTRA GROUP HOLDINGS PAR	610,000	$12,767	3.0%	$21.22	+0.1%	COMMON STOCK	20603L102
—	CORCEPT THERAPEUTICS INC	147,800	$12,284	2.9%	—	—	Call	218352902
IMVT	IMMUNOVANT INC	698,472	$11,259	2.6%	$23.65	-31.5%	COM	45258J102
SEM	SELECT MED HLDGS CORP	874,915	$11,234	2.6%	$14.11	-6.3%	COM	81619Q105
BHVN	BIOHAVEN LTD	600,000	$9,006	2.1%	$20.40	-28.6%	COM	G1110E107
VRTX	VERTEX PHARMACEUTICALS INC	20,500	$8,029	1.9%	$417.92	0.0%	COM	92532F100
BSX	BOSTON SCIENTIFIC CORP	76,100	$7,430	1.7%	$103.56	0.0%	COM	101137107
CDNA	CAREDX INC	504,030	$7,329	1.7%	$17.83	-20.0%	COM	14167L103
ACHC	ACADIA HEALTHCARE COMPANY IN	250,000	$6,190	1.4%	$41.81	-46.6%	COM	00404A109
TECX	TECTONIC THERAPEUTIC INC	379,254	$5,950	1.4%	$31.39	-34.2%	COM	878972108
KIDS	ORTHOPEDIATRICS CORP	308,707	$5,720	1.3%	$20.84	-1.2%	COM	68752L100
CRBP	CORBUS PHARMACEUTICALS HLDGS	343,400	$4,344	1.0%	$20.33	-53.2%	COM NEW	21833P301
RCKT	ROCKET PHARMACEUTICALS INC	1,267,965	$4,134	1.0%	$13.68	-77.0%	COM	77313F106
PRCT	PROCEPT BIOROBOTICS CORP	76,991	$2,748	0.6%	$45.66	0.0%	COM	74276L105
ALGN	ALIGN TECHNOLOGY INC	19,442	$2,435	0.6%	$156.63	0.0%	COM	016255101
ARGX	ARGENX SE	3,300	$2,434	0.6%	$576.53	—	SPONSORED ADR	04016X101
TWST	TWIST BIOSCIENCE CORP	75,000	$2,111	0.5%	$30.29	0.0%	COM	90184D100
—	AKERO THERAPEUTICS INC	39,072	$1,855	0.4%	$47.48	—	COM	00973Y108
CTMX	CYTOMX THERAPEUTICS INC	564,800	$1,802	0.4%	$1.23	+83.7%	COM	23284F105
SGHT	SIGHT SCIENCES INC	439,941	$1,513	0.4%	$5.64	-34.0%	COM	82657M105
OKUR	ONKURE THERAPEUTICS INC	267,959	$737	0.2%	$6.29	-60.6%	COM CL A	68277Q105
SDGR	SCHRODINGER INC	34,830	$699	0.2%	$20.09	0.0%	COM	80810D103
RNTX	REIN THERAPEUTICS INC	567,898	$650	0.2%	$2.99	-57.5%	COM NEW	00887A204
TBI	TRUEBLUE INC	79,476	$487	0.1%	$6.33	0.0%	COM	89785X101
PRTA	PROTHENA CORP PLC	20,000	$195	0.0%	$26.88	-71.4%	SHS	G72800108
PLRX	PLIANT THERAPEUTICS INC	20,487	$30	0.0%	$3.27	-53.4%	COM	729139105
ACTU	ACTUATE THERAPEUTICS ORD	885	$6	0.0%	$7.25	0.0%	COM	005083100