Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
NBIS	NEBIUS GROUP N.V.	40,000	$9.435M	1.8%	$235.88	$215.08	+9.7%	SHS CLASS A	N97284108
BBIO	BRIDGEBIO PHARMA INC	89,151	$5.866M	1.1%	$65.80	$77.87	-15.5%	COM	10806X102
NBIX	NEUROCRINE BIOSCIENCES INC	26,200	$3.716M	0.7%	$141.84	$160.75	-11.8%	COM	64125C109
URNM	SPROTT FDS TR	8,178	$388K	0.1%	$47.46	$52.73	-10.0%	URANI MINER ETF	85208P303
RRC	RANGE RES CORP	7,147	$265K	0.1%	$37.04	$39.27	-5.7%	COM	75281A109
EXE	EXPAND ENERGY CORPORATION	3,046	$256K	0.0%	$84.09	$92.25	-8.8%	COM	165167735
EQT	EQT CORP	5,266	$256K	0.0%	$48.56	$52.40	-7.3%	COM	26884L109
PFE	PFIZER INC	7,406	$211K	0.0%	$28.52	$26.60	+7.2%	COM	717081103
COPY	RBB FUND TRUST	13,250	$203K	0.0%	$15.32	$15.58	-1.7%	TWEEDY BROWNE	75526L860

Increased Positions (21)

SPCX SPACE EXPLORATION TECHN CORP 7.3%

Value $37.72M (+451.8%) Shares 250,000 (+525.0%) Share Price $150.86 Est. Cost/Share $143.58 Unrealized @ Report Date +5.1%

IONS IONIS PHARMACEUTICALS INC 3.0%

Value $15.58M (-38.6%) Shares 349,003 (+9.1%) Share Price $44.65 Est. Cost/Share $46.57 Unrealized @ Report Date -4.1%

CBRS CEREBRAS SYSTEMS INC 3.8%

Value $19.72M (+47.5%) Shares 111,000 (+83.5%) Share Price $177.65 Est. Cost/Share $219.76 Unrealized @ Report Date -19.2%

OPEN OPENDOOR TECHNOLOGIES INC 2.4%

Value $12.18M (-33.1%) Shares 5,140,904 (+30.4%) Share Price $2.37 Est. Cost/Share $4.51 Unrealized @ Report Date -47.4%

AXSM AXSOME THERAPEUTICS INC. 1.5%

Value $7.918M (-19.0%) Shares 42,944 (+7.5%) Share Price $184.39 Est. Cost/Share $87.34 Unrealized @ Report Date +111.1%

ALNY ALNYLAM PHARMACEUTICALS INC 1.0%

Value $5.085M (+48.5%) Shares 20,607 (+81.2%) Share Price $246.74 Est. Cost/Share $301.83 Unrealized @ Report Date -18.3%

BTG B2GOLD CORP 0.3%

Value $1.386M (+90.0%) Shares 265,505 (+36.1%) Share Price $5.22 Est. Cost/Share $4.79 Unrealized @ Report Date +9.0%

SRPT SAREPTA THERAPEUTICS INC 0.6%

Value $3.036M (+23.8%) Shares 166,605 (+22.1%) Share Price $18.22 Est. Cost/Share $19.44 Unrealized @ Report Date -6.3%

RNAC CARTESIAN THERAPEUTICS INC 0.2%

Value $1.118M (-29.3%) Shares 155,000 (+2.2%) Share Price $7.21 Est. Cost/Share $8.06 Unrealized @ Report Date -10.6%

IREN IREN LIMITED 2.9%

Value $15.13M (-2.7%) Shares 370,150 (+8.8%) Share Price $40.88 Est. Cost/Share $40.47 Unrealized @ Report Date +1.0%

ZTS ZOETIS INC 0.3%

Value $1.651M (+32.6%) Shares 23,643 (+36.5%) Share Price $69.83 Est. Cost/Share $88.95 Unrealized @ Report Date -21.5%

ABEV AMBEV SA 0.6%

Value $2.89M (+14.7%) Shares 989,723 (+23.4%) Share Price $2.92 Est. Cost/Share $2.54 Unrealized @ Report Date +14.9%

MGTX MEIRAGTX HLDGS PLC 0.4%

Value $2.294M (-13.4%) Shares 208,512 (+6.3%) Share Price $11.00 Est. Cost/Share $6.72 Unrealized @ Report Date +63.7%

BNTX BIONTECH SE 0.6%

Value $3.155M (+12.7%) Shares 32,100 (+6.6%) Share Price $98.30 Est. Cost/Share $101.20 Unrealized @ Report Date -2.9%

AUTL AUTOLUS THERAPEUTICS LTD 0.2%

Value $911K (+56.6%) Shares 469,490 (+29.2%) Share Price $1.94 Est. Cost/Share $2.92 Unrealized @ Report Date -33.5%

CRSP CRISPR THERAPEUTICS AG 0.5%

Value $2.709M (+10.5%) Shares 48,974 (+8.9%) Share Price $55.32 Est. Cost/Share $50.12 Unrealized @ Report Date +10.4%

TSHA TAYSHA GENE THERAPIES INC 0.2%

Value $1.134M (-16.3%) Shares 232,900 (+17.1%) Share Price $4.87 Est. Cost/Share $3.80 Unrealized @ Report Date +28.0%

BEAM BEAM THERAPEUTICS INC 0.4%

Value $2.232M (-7.5%) Shares 91,282 (+29.9%) Share Price $24.45 Est. Cost/Share $23.01 Unrealized @ Report Date +6.3%

RIG TRANSOCEAN LTD 0.2%

Value $816K (+14.6%) Shares 155,699 (+6.9%) Share Price $5.24 Est. Cost/Share $4.15 Unrealized @ Report Date +26.4%

LULU LULULEMON ATHLETICA INC 0.1%

Value $676K (+16.9%) Shares 7,023 (+38.7%) Share Price $96.19 Est. Cost/Share $128.00 Unrealized @ Report Date -24.9%

MOH MOLINA HEALTHCARE INC 0.1%

Value $769K (+12.8%) Shares 4,064 (+36.4%) Share Price $189.10 Est. Cost/Share $171.77 Unrealized @ Report Date +10.1%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
SPCX	SPACE EXPLORATION TECHN CORP	250,000 (+525.0%)	$37.72M (+451.8%)	7.3%	$150.86	$143.58	+5.1%	CLASS A COM STK	84615Q103
IONS	IONIS PHARMACEUTICALS INC	349,003 (+9.1%)	$15.58M (-38.6%)	3.0%	$44.65	$46.57	-4.1%	COM	462222100
CBRS	CEREBRAS SYSTEMS INC	111,000 (+83.5%)	$19.72M (+47.5%)	3.8%	$177.65	$219.76	-19.2%	COM CL A	15675D103
OPEN	OPENDOOR TECHNOLOGIES INC	5,140,904 (+30.4%)	$12.18M (-33.1%)	2.4%	$2.37	$4.51	-47.4%	COM	683712103
AXSM	AXSOME THERAPEUTICS INC.	42,944 (+7.5%)	$7.918M (-19.0%)	1.5%	$184.39	$87.34	+111.1%	COM	05464T104
ALNY	ALNYLAM PHARMACEUTICALS INC	20,607 (+81.2%)	$5.085M (+48.5%)	1.0%	$246.74	$301.83	-18.3%	COM	02043Q107
BTG	B2GOLD CORP	265,505 (+36.1%)	$1.386M (+90.0%)	0.3%	$5.22	$4.79	+9.0%	COM	11777Q209
SRPT	SAREPTA THERAPEUTICS INC	166,605 (+22.1%)	$3.036M (+23.8%)	0.6%	$18.22	$19.44	-6.3%	COM	803607100
RNAC	CARTESIAN THERAPEUTICS INC	155,000 (+2.2%)	$1.118M (-29.3%)	0.2%	$7.21	$8.06	-10.6%	COM NEW	816212302
IREN	IREN LIMITED	370,150 (+8.8%)	$15.13M (-2.7%)	2.9%	$40.88	$40.47	+1.0%	ORDINARY SHARES	Q4982L109
ZTS	ZOETIS INC	23,643 (+36.5%)	$1.651M (+32.6%)	0.3%	$69.83	$88.95	-21.5%	CL A	98978V103
ABEV	AMBEV SA	989,723 (+23.4%)	$2.89M (+14.7%)	0.6%	$2.92	$2.54	+14.9%	SPONSORED ADR	02319V103
MGTX	MEIRAGTX HLDGS PLC	208,512 (+6.3%)	$2.294M (-13.4%)	0.4%	$11.00	$6.72	+63.7%	COM	G59665102
BNTX	BIONTECH SE	32,100 (+6.6%)	$3.155M (+12.7%)	0.6%	$98.30	$101.20	-2.9%	SPONSORED ADS	09075V102
AUTL	AUTOLUS THERAPEUTICS LTD	469,490 (+29.2%)	$911K (+56.6%)	0.2%	$1.94	$2.92	-33.5%	SPON ADS	05280R100
CRSP	CRISPR THERAPEUTICS AG	48,974 (+8.9%)	$2.709M (+10.5%)	0.5%	$55.32	$50.12	+10.4%	NAMEN AKT	H17182108
TSHA	TAYSHA GENE THERAPIES INC	232,900 (+17.1%)	$1.134M (-16.3%)	0.2%	$4.87	$3.80	+28.0%	COM SHS	877619106
BEAM	BEAM THERAPEUTICS INC	91,282 (+29.9%)	$2.232M (-7.5%)	0.4%	$24.45	$23.01	+6.3%	COM	07373V105
RIG	TRANSOCEAN LTD	155,699 (+6.9%)	$816K (+14.6%)	0.2%	$5.24	$4.15	+26.4%	REGISTERED SHS	H8817H100
LULU	LULULEMON ATHLETICA INC	7,023 (+38.7%)	$676K (+16.9%)	0.1%	$96.19	$128.00	-24.9%	COM	550021109
MOH	MOLINA HEALTHCARE INC	4,064 (+36.4%)	$769K (+12.8%)	0.1%	$189.10	$171.77	+10.1%	COM	60855R100

Exited Positions (12)

ASTS AST SPACEMOBILE INC 2.5%

Value $12.88M Shares 145,000 Share Price $88.86 * Est. Cost/Share $53.79 Unrealized @ Report Date +9.4%

VRTX VERTEX PHARMACEUTICALS INC 0.9%

Value $4.669M Shares 9,400 Share Price $496.73 * Est. Cost/Share $462.80 Unrealized @ Report Date +13.0%

VRDN VIRIDIAN THERAPEUTICS INC 0.6%

Value $3.187M Shares 173,516 Share Price $18.37 * Est. Cost/Share $27.43 Unrealized @ Report Date -24.9%

HIMS HIMS & HERS HEALTH INC 0.5%

Value $2.774M Shares 80,000 Share Price $34.67 * Est. Cost/Share $37.38 Unrealized @ Report Date -20.3%

ZLAB ZAI LAB LTD 0.5%

Value $2.322M Shares 122,189 Share Price $19.00 * Est. Cost/Share $79.02 Unrealized @ Report Date -66.7%

MRNA MODERNA INC 0.4%

Value $2.1M Shares 29,994 Share Price $70.03 * Est. Cost/Share $64.57 Unrealized @ Report Date +198.2%

MICC MAGNUM ICE CREAM CO NV 0.3%

Value $1.496M Shares 98,221 Share Price $15.24 * Est. Cost/Share $15.57 Unrealized @ Report Date +14.2%

WVE WAVE LIFE SCIENCES LTD 0.3%

Value $1.4M Shares 241,010 Share Price $5.81 * Est. Cost/Share $9.86 Unrealized @ Report Date -62.5%

LEGN LEGEND BIOTECH CORP 0.2%

Value $1.022M Shares 35,400 Share Price $28.88 * Est. Cost/Share $26.97 Unrealized @ Report Date -26.3%

TTE TOTALENERGIES SE 0.1%

Value $729K Shares 10,723 Share Price $68.03 * Est. Cost/Share $88.44 Unrealized @ Report Date -3.3%

TDW TIDEWATER INC NEW 0.1%

Value $579K Shares 8,683 Share Price $66.63 * Est. Cost/Share $55.04 Unrealized @ Report Date +47.4%

CSAN COSAN S A 0.0%

Value $150K Shares 52,000 Share Price $2.88 * Est. Cost/Share $3.54 Unrealized @ Report Date -15.1%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ASTS	AST SPACEMOBILE INC	145,000	$12.88M	2.5%	$88.86 *	$53.79	+9.4%	—	00217D100
VRTX	VERTEX PHARMACEUTICALS INC	9,400	$4.669M	0.9%	$496.73 *	$462.80	+13.0%	—	92532F100
VRDN	VIRIDIAN THERAPEUTICS INC	173,516	$3.187M	0.6%	$18.37 *	$27.43	-24.9%	—	92790C104
HIMS	HIMS & HERS HEALTH INC	80,000	$2.774M	0.5%	$34.67 *	$37.38	-20.3%	—	433000106
ZLAB	ZAI LAB LTD	122,189	$2.322M	0.5%	$19.00 *	$79.02	-66.7%	—	98887Q104
MRNA	MODERNA INC	29,994	$2.1M	0.4%	$70.03 *	$64.57	+198.2%	—	60770K107
MICC	MAGNUM ICE CREAM CO NV	98,221	$1.496M	0.3%	$15.24 *	$15.57	+14.2%	—	N5505D105
WVE	WAVE LIFE SCIENCES LTD	241,010	$1.4M	0.3%	$5.81 *	$9.86	-62.5%	—	Y95308105
LEGN	LEGEND BIOTECH CORP	35,400	$1.022M	0.2%	$28.88 *	$26.97	-26.3%	—	52490G102
TTE	TOTALENERGIES SE	10,723	$729K	0.1%	$68.03 *	$88.44	-3.3%	—	F92124100
TDW	TIDEWATER INC NEW	8,683	$579K	0.1%	$66.63 *	$55.04	+47.4%	—	88642R109
CSAN	COSAN S A	52,000	$150K	0.0%	$2.88 *	$3.54	-15.1%	—	22113B103

Decreased Positions (12)

TSLA TESLA INC 15.5%

Value $79.83M (-16.8%) Shares 225,000 (-1.3%) Share Price $354.81 Est. Cost/Share $213.74 Unrealized @ Report Date +66.0%

QURE UNIQURE NV 1.0%

Value $5.223M (-65.5%) Shares 216,197 (-34.2%) Share Price $24.16 Est. Cost/Share $16.05 Unrealized @ Report Date +50.5%

SPOT SPOTIFY TECHNOLOGY S A 3.1%

Value $16.08M (-36.3%) Shares 33,000 (-40.0%) Share Price $487.38 Est. Cost/Share $198.24 Unrealized @ Report Date +145.8%

RARE ULTRAGENYX PHARMACEUTICAL IN 0.7%

Value $3.503M (-69.0%) Shares 233,037 (-31.2%) Share Price $15.03 Est. Cost/Share $47.15 Unrealized @ Report Date -68.1%

ARWR ARROWHEAD PHARMACEUTICALS IN 2.7%

Value $14.13M (-26.0%) Shares 215,818 (-7.9%) Share Price $65.45 Est. Cost/Share $35.12 Unrealized @ Report Date +86.3%

URGN UROGEN PHARMA LTD 0.9%

Value $4.385M (-43.3%) Shares 107,915 (-48.6%) Share Price $40.63 Est. Cost/Share $15.30 Unrealized @ Report Date +165.6%

SHOP SHOPIFY INC 8.8%

Value $45.23M (+7.1%) Shares 305,000 (-17.6%) Share Price $148.30 Est. Cost/Share $50.26 Unrealized @ Report Date +195.1%

ARQT ARCUTIS BIOTHERAPEUTICS INC 1.7%

Value $8.806M (-15.9%) Shares 333,193 (-16.6%) Share Price $26.43 Est. Cost/Share $14.05 Unrealized @ Report Date +88.1%

KRYS KRYSTAL BIOTECH INC 0.6%

Value $3.316M (-20.1%) Shares 9,970 (-10.7%) Share Price $332.56 Est. Cost/Share $135.26 Unrealized @ Report Date +145.9%

NOV NOV INC 0.1%

Value $638K (-18.2%) Shares 34,050 (-19.0%) Share Price $18.73 Est. Cost/Share $15.12 Unrealized @ Report Date +23.9%

NU NU HLDGS LTD 0.1%

Value $483K (-17.8%) Shares 38,168 (-13.3%) Share Price $12.66 Est. Cost/Share $13.48 Unrealized @ Report Date -6.1%

SA SEABRIDGE GOLD INC 0.1%

Value $402K (-5.5%) Shares 14,172 (-14.2%) Share Price $28.34 Est. Cost/Share $25.74 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
TSLA	TESLA INC	225,000 (-1.3%)	$79.83M (-16.8%)	15.5%	$354.81	$213.74	+66.0%	COM	88160R101
QURE	UNIQURE NV	216,197 (-34.2%)	$5.223M (-65.5%)	1.0%	$24.16	$16.05	+50.5%	SHS	N90064101
SPOT	SPOTIFY TECHNOLOGY S A	33,000 (-40.0%)	$16.08M (-36.3%)	3.1%	$487.38	$198.24	+145.8%	SHS	L8681T102
RARE	ULTRAGENYX PHARMACEUTICAL IN	233,037 (-31.2%)	$3.503M (-69.0%)	0.7%	$15.03	$47.15	-68.1%	COM	90400D108
ARWR	ARROWHEAD PHARMACEUTICALS IN	215,818 (-7.9%)	$14.13M (-26.0%)	2.7%	$65.45	$35.12	+86.3%	COM	04280A100
URGN	UROGEN PHARMA LTD	107,915 (-48.6%)	$4.385M (-43.3%)	0.9%	$40.63	$15.30	+165.6%	COM	M96088105
SHOP	SHOPIFY INC	305,000 (-17.6%)	$45.23M (+7.1%)	8.8%	$148.30	$50.26	+195.1%	CL A SUB VTG SHS	82509L107
ARQT	ARCUTIS BIOTHERAPEUTICS INC	333,193 (-16.6%)	$8.806M (-15.9%)	1.7%	$26.43	$14.05	+88.1%	COM	03969K108
KRYS	KRYSTAL BIOTECH INC	9,970 (-10.7%)	$3.316M (-20.1%)	0.6%	$332.56	$135.26	+145.9%	COM	501147102
NOV	NOV INC	34,050 (-19.0%)	$638K (-18.2%)	0.1%	$18.73	$15.12	+23.9%	COM	62955J103
NU	NU HLDGS LTD	38,168 (-13.3%)	$483K (-17.8%)	0.1%	$12.66	$13.48	-6.1%	ORD SHS CL A	G6683N103
SA	SEABRIDGE GOLD INC	14,172 (-14.2%)	$402K (-5.5%)	0.1%	$28.34	$25.74	—	COM	811927102

Unchanged Positions (16)

PLTR PALANTIR TECHNOLOGIES INC 7.3%

Value $37.41M Shares 200,000 Share Price $187.05 Est. Cost/Share $15.54 Unrealized @ Report Date +1103.5%

LMND LEMONADE INC 2.4%

Value $12.2M Shares 270,259 Share Price $45.14 Est. Cost/Share $56.88 Unrealized @ Report Date -20.6%

NVDA NVIDIA CORPORATION 3.6%

Value $18.5M Shares 81,000 Share Price $228.38 Est. Cost/Share $100.98 Unrealized @ Report Date +126.2%

AMD ADVANCED MICRO DEVICES INC 7.4%

Value $37.93M Shares 62,000 Share Price $611.76 Est. Cost/Share $163.06 Unrealized @ Report Date +275.2%

AMZN AMAZON COM INC 6.8%

Value $34.88M Shares 140,000 Share Price $249.15 Est. Cost/Share $135.14 Unrealized @ Report Date +84.4%

PRQR PROQR THRAPEUTICS N V 1.8%

Value $9.075M Shares 5,467,149 Share Price $1.66 Est. Cost/Share $6.48 Unrealized @ Report Date -74.4%

DNLI DENALI THERAPEUTICS INC 0.9%

Value $4.751M Shares 229,857 Share Price $20.67 Est. Cost/Share $19.91 Unrealized @ Report Date +3.8%

BIIB BIOGEN INC 2.1%

Value $10.93M Shares 48,400 Share Price $225.88 Est. Cost/Share $145.32 Unrealized @ Report Date +55.4%

BMRN BIOMARIN PHARMACEUTICAL INC 0.9%

Value $4.5M Shares 75,000 Share Price $60.00 Est. Cost/Share $58.30 Unrealized @ Report Date +2.9%

LXEO LEXEO THERAPEUTICS INC 0.1%

Value $524K Shares 155,000 Share Price $3.38 Est. Cost/Share $6.84 Unrealized @ Report Date -50.6%

RCKT ROCKET PHARMACEUTICALS INC 0.1%

Value $642K Shares 244,146 Share Price $2.63 Est. Cost/Share $13.46 Unrealized @ Report Date -80.5%

FATE FATE THERAPEUTICS INC 0.2%

Value $982K Shares 414,311 Share Price $2.37 Est. Cost/Share $1.58 Unrealized @ Report Date +50.0%

VYGR VOYAGER THERAPEUTICS INC 0.1%

Value $322K Shares 120,000 Share Price $2.68 Est. Cost/Share $3.91 Unrealized @ Report Date —

FDMT 4D MOLECULAR THERAPEUTICS IN 0.3%

Value $1.289M Shares 90,110 Share Price $14.31 Est. Cost/Share $10.95 Unrealized @ Report Date +30.7%

ENGN ENGENE THERAPEUTICS INC 0.1%

Value $340K Shares 170,000 Share Price $2.00 Est. Cost/Share $1.73 Unrealized @ Report Date —

SD SANDRIDGE ENERGY INC 0.1%

Value $523K Shares 38,792 Share Price $13.49 Est. Cost/Share $12.11 Unrealized @ Report Date +11.4%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
PLTR	PALANTIR TECHNOLOGIES INC	200,000	$37.41M	7.3%	$187.05	$15.54	+1103.5%	CL A	69608A108
LMND	LEMONADE INC	270,259	$12.2M	2.4%	$45.14	$56.88	-20.6%	COM	52567D107
NVDA	NVIDIA CORPORATION	81,000	$18.5M	3.6%	$228.38	$100.98	+126.2%	COM	67066G104
AMD	ADVANCED MICRO DEVICES INC	62,000	$37.93M	7.4%	$611.76	$163.06	+275.2%	COM	007903107
AMZN	AMAZON COM INC	140,000	$34.88M	6.8%	$249.15	$135.14	+84.4%	COM	023135106
PRQR	PROQR THRAPEUTICS N V	5,467,149	$9.075M	1.8%	$1.66	$6.48	-74.4%	SHS EURO	N71542109
DNLI	DENALI THERAPEUTICS INC	229,857	$4.751M	0.9%	$20.67	$19.91	+3.8%	COM	24823R105
BIIB	BIOGEN INC	48,400	$10.93M	2.1%	$225.88	$145.32	+55.4%	COM	09062X103
BMRN	BIOMARIN PHARMACEUTICAL INC	75,000	$4.5M	0.9%	$60.00	$58.30	+2.9%	COM	09061G101
LXEO	LEXEO THERAPEUTICS INC	155,000	$524K	0.1%	$3.38	$6.84	-50.6%	COM	52886X107
RCKT	ROCKET PHARMACEUTICALS INC	244,146	$642K	0.1%	$2.63	$13.46	-80.5%	COM	77313F106
FATE	FATE THERAPEUTICS INC	414,311	$982K	0.2%	$2.37	$1.58	+50.0%	COM	31189P102
VYGR	VOYAGER THERAPEUTICS INC	120,000	$322K	0.1%	$2.68	$3.91	—	COM	92915B106
FDMT	4D MOLECULAR THERAPEUTICS IN	90,110	$1.289M	0.3%	$14.31	$10.95	+30.7%	COM	35104E100
ENGN	ENGENE THERAPEUTICS INC	170,000	$340K	0.1%	$2.00	$1.73	—	COM	29286X101
SD	SANDRIDGE ENERGY INC	38,792	$523K	0.1%	$13.49	$12.11	+11.4%	COM NEW	80007P869