GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value: $242M (100.0% shares, 0.0% debt)

Holdings (30)

AMLX AMYLYX PHARMACEUTICALS INC 9.5%
Value $23.1M Shares 1,700,000 Est. Cost $3.68 Unrealized +155.7%
RZLT REZOLUTE INC COM NEW 9.5%
Value $23.05M Shares 2,451,809 Est. Cost $4.03 Unrealized +65.3%
NKTR NEKTAR THERAPEUTICS COM NEW 7.0%
Value $17.07M Shares 300,000 Est. Cost $33.10 Unrealized 0.0%
ZURA ZURA BIO LTD CLASS A ORD SHS 6.8%
Value $16.52M Shares 3,815,930 Est. Cost $5.64 Unrealized -68.1%
SLNO SOLENO THERAPEUTICS INC 6.3%
Value $15.21M Shares 225,000 Est. Cost $74.14 Unrealized 0.0%
ASND ASCENDIS PHARMA A/S SPONSORED ADR 6.1%
Value $14.91M Shares 75,000 Est. Cost $198.81 Unrealized
ABVX ABIVAX SA SPONSORED ADS 5.3%
Value $12.73M Shares 150,000 Est. Cost $12.06 Unrealized
APGE APOGEE THERAPEUTICS INC 5.0%
Value $12.08M Shares 304,000 Est. Cost $38.18 Unrealized 0.0%
DNTH DIANTHUS THERAPEUTICS INC 4.3%
Value $10.46M Shares 265,803 Est. Cost $25.56 Unrealized 0.0%
CYTK CYTOKINETICS INC COM NEW 3.4%
Value $8.244M Shares 150,000 Est. Cost $51.61 Unrealized -20.2%
IMVT IMMUNOVANT INC 3.3%
Value $8.06M Shares 500,000 Est. Cost $18.67 Unrealized -13.3%
XENE XENON PHARMACEUTICALS INC 3.3%
Value $8.03M Shares 200,000 Est. Cost $41.35 Unrealized -14.8%
NGNE NEUROGENE INC 3.2%
Value $7.743M Shares 446,814 Est. Cost $14.71 Unrealized +36.5%
EPRX EUPRAXIA PHARMACEUTICALS INC 2.9%
Value $7.08M Shares 1,200,000 Est. Cost $5.44 Unrealized 0.0%
UPB UPSTREAM BIO INC 2.3%
Value $5.643M Shares 300,000 Est. Cost $22.33 Unrealized -30.4%
JBIO JADE BIOSCIENCES INC COM NEW 2.3%
Value $5.459M Shares 632,599 Est. Cost $27.97 Unrealized -70.8%
IONS IONIS PHARMACEUTICALS INC 2.2%
Value $5.234M Shares 80,000 Est. Cost $35.97 Unrealized +35.7%
AKERO THERAPEUTICS INC 2.0%
Value $4.931M Shares 103,848 Est. Cost $53.36 Unrealized
TSHA TAYSHA GENE THERAPIES INC COM SHS 2.0%
Value $4.905M Shares 1,500,000 Est. Cost $2.17 Unrealized +30.3%
CNTX CONTEXT THERAPEUTICS INC 1.9%
Value $4.538M Shares 4,683,711 Est. Cost $1.72 Unrealized -53.0%
PHVS PHARVARIS N V 1.6%
Value $3.87M Shares 155,105 Est. Cost $22.18 Unrealized 0.0%
DBVT DBV TECHNOLOGIES S A SPONSORED ADS 1.6%
Value $3.786M Shares 378,594 Est. Cost $9.17 Unrealized
LEGN LEGEND BIOTECH CORP SPONSORED ADS 1.5%
Value $3.7M Shares 113,460 Est. Cost $34.87 Unrealized
ORKA ORUKA THERAPEUTICS INC 1.5%
Value $3.525M Shares 183,330 Est. Cost $14.82 Unrealized 0.0%
UNCY UNICYCIVE THERAPEUTICS INC COM NEW 1.4%
Value $3.473M Shares 796,558 Est. Cost $6.18 Unrealized -29.5%
SANA SANA BIOTECHNOLOGY INC 1.0%
Value $2.485M Shares 700,000 Est. Cost $3.62 Unrealized 0.0%
ABSI ABSCI CORPORATION 1.0%
Value $2.421M Shares 796,438 Est. Cost $2.76 Unrealized 0.0%
HRMY HRMY 10/17/2025 40 Call 1.0%
Value $2.343M Shares 85,000 Est. Cost Unrealized
PLRX PLIANT THERAPEUTICS INC 0.5%
Value $1.258M Shares 850,000 Est. Cost $16.18 Unrealized -90.6%
CAPR CAPR 12/19/2025 7.5 Put 0.3%
Value $632K Shares 87,700 Est. Cost Unrealized