TIZIANA LIFE SCIENCES LTD

Ticker: TLSA CUSIP: G88912103 Class: COMMON SHARES

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (5)

Focus Partners Wealth

Value ($000) $119 Shares 79,971

OMERS ADMINISTRATION Corp

Value ($000) $59 Shares 39,600

Steward Partners Investment Advisory, LLC

Value ($000) $0 Shares 245

HRT FINANCIAL LP

Value ($000) $0 Shares 24,504

Value ($000) $0 Shares 500

Institution	Shares	Value ($000)
Focus Partners Wealth	79,971	$119
OMERS ADMINISTRATION Corp	39,600	$59
Steward Partners Investment Advisory, LLC	245	$0
HRT FINANCIAL LP	24,504	$0
CWM, LLC	500	$0

Increased Positions (4)

GOLDMAN SACHS GROUP INC

Value ($000) $164 (+254.5%) Shares 110,290 (+413.9%)

Value ($000) $157 (+207.2%) Shares 105,218 (+345.3%)

Zhang Financial LLC

Value ($000) $149 (-18.2%) Shares 99,900 (+18.6%)

MARSHALL WACE, LLP

Value ($000) $420 (-27.4%) Shares 282,017 (+5.2%)

Institution	Prev Shares	Curr Shares	Change
GOLDMAN SACHS GROUP INC	21,460	110,290	+88,830 (+413.9%)
UBS Group AG	23,630	105,218	+81,588 (+345.3%)
Zhang Financial LLC	84,200	99,900	+15,700 (+18.6%)
MARSHALL WACE, LLP	268,012	282,017	+14,005 (+5.2%)

Decreased Positions (6)

Dauntless Investment Group, LLC

Value ($000) $1,271 (-78.5%) Shares 1,759,782 (-35.7%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $77 (-85.2%) Shares 51,589 (-78.6%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $20 (-85.3%) Shares 13,089 (-78.7%)

Value ($000) $78 (-62.9%) Shares 52,156 (-46.3%)

HSBC HOLDINGS PLC

Value ($000) $94 (-41.0%) Shares 62,437 (-17.2%)

US BANCORP \DE\

Value ($000) $1 (-93.2%) Shares 1,000 (-90.2%)

Institution	Prev Shares	Curr Shares	Change
Dauntless Investment Group, LLC	2,735,933	1,759,782	-976,151 (-35.7%)
MILLENNIUM MANAGEMENT LLC	240,814	51,589	-189,225 (-78.6%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	61,530	13,089	-48,441 (-78.7%)
MORGAN STANLEY	97,102	52,156	-44,946 (-46.3%)
HSBC HOLDINGS PLC	75,365	62,437	-12,928 (-17.2%)
US BANCORP \DE\	10,157	1,000	-9,157 (-90.2%)

Exited Positions (6)

ARS Investment Partners, LLC

Value ($000) $66 Shares 30,700

Kovitz Investment Group Partners, LLC

Value ($000) $171 Shares 79,365

Caitlin John, LLC

Value ($000) $8 Shares 3,500

Quadrature Capital Ltd

Value ($000) $81 Shares 37,405

Value ($000) $46 Shares 47,500

JANE STREET GROUP, LLC

Value ($000) $39 Shares 17,987

Institution	Prev Shares	Prev Value ($000)
ARS Investment Partners, LLC	30,700	$66
Kovitz Investment Group Partners, LLC	79,365	$171
Caitlin John, LLC	3,500	$8
Quadrature Capital Ltd	37,405	$81
BARCLAYS PLC	47,500	$46
JANE STREET GROUP, LLC	17,987	$39