GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q3 2015 (← Previous) (Next →)

Filing Date: Nov 16, 2015

Total Value: $253M (100.0% shares, 0.0% debt)

Holdings (36)

VNDA VANDA PHARMACEUTICALS INC 7.7%

Value $19.34M Shares 1,715,000 Est. Cost $11.46 Unrealized +6.8%

— FIVE PRIME THERAPEUTICS INC 7.5%

Value $18.88M Shares 1,226,785 Est. Cost $20.62 Unrealized —

— CONNECTURE INC 7.4%

Value $18.82M Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ADAMAS PHARMACEUTICALS INC 7.3%

Value $18.58M Shares 1,110,000 Est. Cost $18.53 Unrealized —

— ZOGENIX INC 7.3%

Value $18.4M Shares 1,362,763 Est. Cost $13.50 Unrealized —

— DYAX CORP 5.7%

Value $14.32M Shares 750,000 Est. Cost $20.69 Unrealized —

— RELYPSA INC 5.6%

Value $14.23M Shares 769,047 Est. Cost $23.06 Unrealized —

— GW PHARMACEUTICALS PLC 3.8%

Value $9.484M Shares 103,800 Est. Cost — Unrealized —

— GW PHARMACEUTICALS PLC 3.6%

Value $9.137M Shares 100,000 Est. Cost — Unrealized —

EXEL EXELIXIS, INC 3.5%

Value $8.92M Shares 1,590,000 Est. Cost $5.44 Unrealized 0.0%

— PARATEK PHARMACEUTICALS INC 3.4%

Value $8.624M Shares 453,878 Est. Cost $25.19 Unrealized —

— TETRAPHASE PHARMACEUTICALS I 3.3%

Value $8.355M Shares 1,120,000 Est. Cost $7.46 Unrealized —

— RAPTOR PHARMACEUTICAL CORP 3.2%

Value $8.077M Shares 1,335,000 Est. Cost $6.05 Unrealized —

— ALCOBRA LTD 2.9%

Value $7.279M Shares 1,205,183 Est. Cost $5.79 Unrealized —

— ARADIGM CORP 2.9%

Value $7.221M Shares 1,002,962 Est. Cost $8.85 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 2.7%

Value $6.917M Shares 2,457,144 Est. Cost $3.52 Unrealized -2.8%

— OCERA THERAPEUTICS INC 2.5%

Value $6.206M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— SYNERGY PHARMACEUTICALS DEL 2.4%

Value $6.019M Shares 1,135,580 Est. Cost $8.30 Unrealized —

— MEDICINES CO 2.3%

Value $5.694M Shares 150,000 Est. Cost $37.96 Unrealized —

VCEL VERICEL CORP 2.2%

Value $5.653M Shares 2,086,028 Est. Cost $2.85 Unrealized +15.4%

— BOVIE MEDICAL CORP 2.1%

Value $5.226M Shares 2,680,000 Est. Cost $2.72 Unrealized —

— STEMLINE THERAPEUTICS INC 1.7%

Value $4.196M Shares 475,200 Est. Cost $14.47 Unrealized —

— ALIMERA SCIENCES INC 1.5%

Value $3.72M Shares 1,683,162 Est. Cost $6.86 Unrealized —

— CALADRIUS BIOSCIENCES INC 1.3%

Value $3.351M Shares 2,248,781 Est. Cost $1.87 Unrealized —

— TENAX THERAPEUTICS INC 1.3%

Value $3.326M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.0%

Value $2.633M Shares 3,250,000 Est. Cost $2.35 Unrealized —

— ANTARES PHARMA INC 0.7%

Value $1.732M Shares 1,018,627 Est. Cost $2.08 Unrealized —

— BIODEL INC 0.6%

Value $1.459M Shares 3,316,966 Est. Cost $1.03 Unrealized —

— AQUINOX PHARMACEUTICALS INC 0.6%

Value $1.407M Shares 100,000 Est. Cost $14.07 Unrealized —

— OSIRIS THERAPEUTICS INC NEW 0.5%

Value $1.385M Shares 75,000 Est. Cost $18.47 Unrealized —

— FLEXION THERAPEUTICS INC 0.4%

Value $985K Shares 66,300 Est. Cost — Unrealized —

— THRESHOLD PHARMACEUTICALS INC 0.3%

Value $858K Shares 210,800 Est. Cost — Unrealized —

— TRANSITION THERAPEUTICS INC 0.3%

Value $800K Shares 447,026 Est. Cost $1.79 Unrealized —

— DISCOVERY LABORATORIES INC N 0.3%

Value $759K Shares 2,530,532 Est. Cost $0.30 Unrealized —

— DERMA SCIENCES INC CMN 0.2%

Value $477K Shares 101,235 Est. Cost $12.35 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.1%

Value $347K Shares 151,611 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
VNDA	VANDA PHARMACEUTICALS INC	1,715,000	$19.34M	7.7%	$11.46	+6.8%	COM	921659108
—	FIVE PRIME THERAPEUTICS INC	1,226,785	$18.88M	7.5%	$20.62	—	COM	33830X104
—	CONNECTURE INC	4,127,232	$18.82M	7.4%	$9.01	—	COM	20786J106
—	ADAMAS PHARMACEUTICALS INC	1,110,000	$18.58M	7.3%	$18.53	—	COM	00548A106
—	ZOGENIX INC	1,362,763	$18.4M	7.3%	$13.50	—	COM NEW	98978L204
—	DYAX CORP	750,000	$14.32M	5.7%	$20.69	—	COM	26746E103
—	RELYPSA INC	769,047	$14.23M	5.6%	$23.06	—	COM	759531106
—	GW PHARMACEUTICALS PLC	103,800	$9.484M	3.8%	—	—	Call	36197T103
—	GW PHARMACEUTICALS PLC	100,000	$9.137M	3.6%	—	—	Put	36197T103
EXEL	EXELIXIS, INC	1,590,000	$8.92M	3.5%	$5.44	0.0%	COM	30161Q104
—	PARATEK PHARMACEUTICALS INC	453,878	$8.624M	3.4%	$25.19	—	COM	699374302
—	TETRAPHASE PHARMACEUTICALS I	1,120,000	$8.355M	3.3%	$7.46	—	COM	88165N105
—	RAPTOR PHARMACEUTICAL CORP	1,335,000	$8.077M	3.2%	$6.05	—	COM	75382F106
—	ALCOBRA LTD	1,205,183	$7.279M	2.9%	$5.79	—	SHS	M2239P109
—	ARADIGM CORP	1,002,962	$7.221M	2.9%	$8.85	—	COM NO PAR NEW	038505400
AUPH	AURINIA PHARMACEUTICALS INC	2,457,144	$6.917M	2.7%	$3.52	-2.8%	COM	05156V102
—	OCERA THERAPEUTICS INC	1,963,777	$6.206M	2.5%	$6.20	—	COM	67552A108
—	SYNERGY PHARMACEUTICALS DEL	1,135,580	$6.019M	2.4%	$8.30	—	COM NEW	871639308
—	MEDICINES CO	150,000	$5.694M	2.3%	$37.96	—	COM	584688105
VCEL	VERICEL CORP	2,086,028	$5.653M	2.2%	$2.85	+15.4%	COM	92346J108
—	BOVIE MEDICAL CORP	2,680,000	$5.226M	2.1%	$2.72	—	COM	10211F100
—	STEMLINE THERAPEUTICS INC	475,200	$4.196M	1.7%	$14.47	—	COM	85858C107
—	ALIMERA SCIENCES INC	1,683,162	$3.72M	1.5%	$6.86	—	COM	016259103
—	CALADRIUS BIOSCIENCES INC	2,248,781	$3.351M	1.3%	$1.87	—	COM	128058104
—	TENAX THERAPEUTICS INC	1,108,593	$3.326M	1.3%	$3.93	—	COM	88032L100
—	SUNESIS PHARMACEUTICALS INC	3,250,000	$2.633M	1.0%	$2.35	—	COM NEW	867328601
—	ANTARES PHARMA INC	1,018,627	$1.732M	0.7%	$2.08	—	COM	036642106
—	BIODEL INC	3,316,966	$1.459M	0.6%	$1.03	—	COM NEW	09064M204
—	AQUINOX PHARMACEUTICALS INC	100,000	$1.407M	0.6%	$14.07	—	COM	03842B101
—	OSIRIS THERAPEUTICS INC NEW	75,000	$1.385M	0.5%	$18.47	—	COM	68827R108
—	FLEXION THERAPEUTICS INC	66,300	$985K	0.4%	—	—	Call	33938J106
—	THRESHOLD PHARMACEUTICALS INC	210,800	$858K	0.3%	—	—	Call	885807206
—	TRANSITION THERAPEUTICS INC	447,026	$800K	0.3%	$1.79	—	COM NEW	893716209
—	DISCOVERY LABORATORIES INC N	2,530,532	$759K	0.3%	$0.30	—	COM NEW	254668403
—	DERMA SCIENCES INC CMN	101,235	$477K	0.2%	$12.35	—	COM	249827502
—	STREAMLINE HEALTH SOLUTIONS	151,611	$347K	0.1%	$6.45	—	COM	86323X106