GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q3 2015 (← Previous) (Next →)

Filing Date: Nov 16, 2015

Total Value ($000): $252,823 (100.0% shares, 0.0% debt)

Holdings (36)

VNDA VANDA PHARMACEUTICALS INC 7.7%

Value ($000) $19,345 Shares 1,715,000 Est. Cost $11.46 Unrealized +6.8%

— FIVE PRIME THERAPEUTICS INC 7.5%

Value ($000) $18,880 Shares 1,226,785 Est. Cost $20.62 Unrealized —

— CONNECTURE INC 7.4%

Value ($000) $18,820 Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ADAMAS PHARMACEUTICALS INC 7.3%

Value ($000) $18,581 Shares 1,110,000 Est. Cost $18.53 Unrealized —

— ZOGENIX INC 7.3%

Value ($000) $18,397 Shares 1,362,763 Est. Cost $13.50 Unrealized —

— DYAX CORP 5.7%

Value ($000) $14,318 Shares 750,000 Est. Cost $20.69 Unrealized —

— RELYPSA INC 5.6%

Value ($000) $14,235 Shares 769,047 Est. Cost $23.06 Unrealized —

— GW PHARMACEUTICALS PLC 3.8%

Value ($000) $9,484 Shares 103,800 Est. Cost — Unrealized —

— GW PHARMACEUTICALS PLC 3.6%

Value ($000) $9,137 Shares 100,000 Est. Cost — Unrealized —

EXEL EXELIXIS, INC 3.5%

Value ($000) $8,920 Shares 1,590,000 Est. Cost $5.44 Unrealized 0.0%

— PARATEK PHARMACEUTICALS INC 3.4%

Value ($000) $8,624 Shares 453,878 Est. Cost $25.19 Unrealized —

— TETRAPHASE PHARMACEUTICALS I 3.3%

Value ($000) $8,355 Shares 1,120,000 Est. Cost $7.46 Unrealized —

— RAPTOR PHARMACEUTICAL CORP 3.2%

Value ($000) $8,077 Shares 1,335,000 Est. Cost $6.05 Unrealized —

— ALCOBRA LTD 2.9%

Value ($000) $7,279 Shares 1,205,183 Est. Cost $5.79 Unrealized —

— ARADIGM CORP 2.9%

Value ($000) $7,221 Shares 1,002,962 Est. Cost $8.85 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 2.7%

Value ($000) $6,917 Shares 2,457,144 Est. Cost $3.52 Unrealized -2.8%

— OCERA THERAPEUTICS INC 2.5%

Value ($000) $6,206 Shares 1,963,777 Est. Cost $6.20 Unrealized —

— SYNERGY PHARMACEUTICALS DEL 2.4%

Value ($000) $6,019 Shares 1,135,580 Est. Cost $8.30 Unrealized —

— MEDICINES CO 2.3%

Value ($000) $5,694 Shares 150,000 Est. Cost $37.96 Unrealized —

VCEL VERICEL CORP 2.2%

Value ($000) $5,653 Shares 2,086,028 Est. Cost $2.85 Unrealized +15.4%

— BOVIE MEDICAL CORP 2.1%

Value ($000) $5,226 Shares 2,680,000 Est. Cost $2.72 Unrealized —

— STEMLINE THERAPEUTICS INC 1.7%

Value ($000) $4,196 Shares 475,200 Est. Cost $14.47 Unrealized —

— ALIMERA SCIENCES INC 1.5%

Value ($000) $3,720 Shares 1,683,162 Est. Cost $6.86 Unrealized —

— CALADRIUS BIOSCIENCES INC 1.3%

Value ($000) $3,351 Shares 2,248,781 Est. Cost $1.87 Unrealized —

— TENAX THERAPEUTICS INC 1.3%

Value ($000) $3,326 Shares 1,108,593 Est. Cost $3.93 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.0%

Value ($000) $2,633 Shares 3,250,000 Est. Cost $2.35 Unrealized —

— ANTARES PHARMA INC 0.7%

Value ($000) $1,732 Shares 1,018,627 Est. Cost $2.08 Unrealized —

— BIODEL INC 0.6%

Value ($000) $1,459 Shares 3,316,966 Est. Cost $1.03 Unrealized —

— AQUINOX PHARMACEUTICALS INC 0.6%

Value ($000) $1,407 Shares 100,000 Est. Cost $14.07 Unrealized —

— OSIRIS THERAPEUTICS INC NEW 0.5%

Value ($000) $1,385 Shares 75,000 Est. Cost $18.47 Unrealized —

— FLEXION THERAPEUTICS INC 0.4%

Value ($000) $985 Shares 66,300 Est. Cost — Unrealized —

— THRESHOLD PHARMACEUTICALS INC 0.3%

Value ($000) $858 Shares 210,800 Est. Cost — Unrealized —

— TRANSITION THERAPEUTICS INC 0.3%

Value ($000) $800 Shares 447,026 Est. Cost $1.79 Unrealized —

— DISCOVERY LABORATORIES INC N 0.3%

Value ($000) $759 Shares 2,530,532 Est. Cost $0.30 Unrealized —

— DERMA SCIENCES INC CMN 0.2%

Value ($000) $477 Shares 101,235 Est. Cost $12.35 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.1%

Value ($000) $347 Shares 151,611 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
VNDA	VANDA PHARMACEUTICALS INC	1,715,000	$19,345	7.7%	$11.46	+6.8%	COM	921659108
—	FIVE PRIME THERAPEUTICS INC	1,226,785	$18,880	7.5%	$20.62	—	COM	33830X104
—	CONNECTURE INC	4,127,232	$18,820	7.4%	$9.01	—	COM	20786J106
—	ADAMAS PHARMACEUTICALS INC	1,110,000	$18,581	7.3%	$18.53	—	COM	00548A106
—	ZOGENIX INC	1,362,763	$18,397	7.3%	$13.50	—	COM NEW	98978L204
—	DYAX CORP	750,000	$14,318	5.7%	$20.69	—	COM	26746E103
—	RELYPSA INC	769,047	$14,235	5.6%	$23.06	—	COM	759531106
—	GW PHARMACEUTICALS PLC	103,800	$9,484	3.8%	—	—	Call	36197T103
—	GW PHARMACEUTICALS PLC	100,000	$9,137	3.6%	—	—	Put	36197T103
EXEL	EXELIXIS, INC	1,590,000	$8,920	3.5%	$5.44	0.0%	COM	30161Q104
—	PARATEK PHARMACEUTICALS INC	453,878	$8,624	3.4%	$25.19	—	COM	699374302
—	TETRAPHASE PHARMACEUTICALS I	1,120,000	$8,355	3.3%	$7.46	—	COM	88165N105
—	RAPTOR PHARMACEUTICAL CORP	1,335,000	$8,077	3.2%	$6.05	—	COM	75382F106
—	ALCOBRA LTD	1,205,183	$7,279	2.9%	$5.79	—	SHS	M2239P109
—	ARADIGM CORP	1,002,962	$7,221	2.9%	$8.85	—	COM NO PAR NEW	038505400
AUPH	AURINIA PHARMACEUTICALS INC	2,457,144	$6,917	2.7%	$3.52	-2.8%	COM	05156V102
—	OCERA THERAPEUTICS INC	1,963,777	$6,206	2.5%	$6.20	—	COM	67552A108
—	SYNERGY PHARMACEUTICALS DEL	1,135,580	$6,019	2.4%	$8.30	—	COM NEW	871639308
—	MEDICINES CO	150,000	$5,694	2.3%	$37.96	—	COM	584688105
VCEL	VERICEL CORP	2,086,028	$5,653	2.2%	$2.85	+15.4%	COM	92346J108
—	BOVIE MEDICAL CORP	2,680,000	$5,226	2.1%	$2.72	—	COM	10211F100
—	STEMLINE THERAPEUTICS INC	475,200	$4,196	1.7%	$14.47	—	COM	85858C107
—	ALIMERA SCIENCES INC	1,683,162	$3,720	1.5%	$6.86	—	COM	016259103
—	CALADRIUS BIOSCIENCES INC	2,248,781	$3,351	1.3%	$1.87	—	COM	128058104
—	TENAX THERAPEUTICS INC	1,108,593	$3,326	1.3%	$3.93	—	COM	88032L100
—	SUNESIS PHARMACEUTICALS INC	3,250,000	$2,633	1.0%	$2.35	—	COM NEW	867328601
—	ANTARES PHARMA INC	1,018,627	$1,732	0.7%	$2.08	—	COM	036642106
—	BIODEL INC	3,316,966	$1,459	0.6%	$1.03	—	COM NEW	09064M204
—	AQUINOX PHARMACEUTICALS INC	100,000	$1,407	0.6%	$14.07	—	COM	03842B101
—	OSIRIS THERAPEUTICS INC NEW	75,000	$1,385	0.5%	$18.47	—	COM	68827R108
—	FLEXION THERAPEUTICS INC	66,300	$985	0.4%	—	—	Call	33938J106
—	THRESHOLD PHARMACEUTICALS INC	210,800	$858	0.3%	—	—	Call	885807206
—	TRANSITION THERAPEUTICS INC	447,026	$800	0.3%	$1.79	—	COM NEW	893716209
—	DISCOVERY LABORATORIES INC N	2,530,532	$759	0.3%	$0.30	—	COM NEW	254668403
—	DERMA SCIENCES INC CMN	101,235	$477	0.2%	$12.35	—	COM	249827502
—	STREAMLINE HEALTH SOLUTIONS	151,611	$347	0.1%	$6.45	—	COM	86323X106