GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q4 2015 (← Previous) (Next →)

Filing Date: Feb 16, 2016

Total Value: $238M (100.0% shares, 0.0% debt)

Holdings (25)

— ADAMAS PHARMACEUTICALS INC 17.1%

Value $40.7M Shares 1,437,335 Est. Cost $20.76 Unrealized —

— FIVE PRIME THERAPEUTICS INC 9.9%

Value $23.64M Shares 569,658 Est. Cost $20.62 Unrealized —

— ZOGENIX INC 8.8%

Value $20.86M Shares 1,414,927 Est. Cost $13.55 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 8.2%

Value $19.55M Shares 2,100,101 Est. Cost $11.18 Unrealized -10.8%

— TETRAPHASE PHARMACEUTICALS I 8.2%

Value $19.46M Shares 1,940,000 Est. Cost $8.55 Unrealized —

— CONNECTURE INC 6.3%

Value $14.9M Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ALCOBRA LTD 5.3%

Value $12.64M Shares 2,012,622 Est. Cost $5.99 Unrealized —

EXEL EXELIXIS, INC 4.8%

Value $11.46M Shares 2,032,494 Est. Cost $5.47 Unrealized +2.2%

— SYNERGY PHARMACEUTICALS DEL 3.7%

Value $8.771M Shares 1,546,888 Est. Cost $7.60 Unrealized —

— SUNESIS PHARMACEUTICALS INC 3.1%

Value $7.404M Shares 8,250,000 Est. Cost $1.47 Unrealized —

— GW PHARMACEUTICALS PLC 2.9%

Value $6.944M Shares 100,000 Est. Cost — Unrealized —

— PARATEK PHARMACEUTICALS INC 2.8%

Value $6.743M Shares 355,459 Est. Cost $25.19 Unrealized —

— RAPTOR PHARMACEUTICAL CORP 2.8%

Value $6.669M Shares 1,282,527 Est. Cost $6.05 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 2.6%

Value $6.16M Shares 2,457,144 Est. Cost $3.52 Unrealized -23.0%

— OCERA THERAPEUTICS INC 2.6%

Value $6.127M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— BOVIE MEDICAL CORP 2.4%

Value $5.628M Shares 2,680,000 Est. Cost $2.72 Unrealized —

VCEL VERICEL CORP 2.3%

Value $5.382M Shares 2,086,028 Est. Cost $2.85 Unrealized -21.5%

— ARADIGM CORP 1.7%

Value $3.982M Shares 1,002,962 Est. Cost $8.85 Unrealized —

— TENAX THERAPEUTICS INC 1.5%

Value $3.636M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— CALADRIUS BIOSCIENCES INC 1.0%

Value $2.429M Shares 2,248,781 Est. Cost $1.87 Unrealized —

— TRANSITION THERAPEUTICS INC 0.7%

Value $1.645M Shares 856,602 Est. Cost $1.85 Unrealized —

— FLEXION THERAPEUTICS INC 0.6%

Value $1.505M Shares 78,100 Est. Cost — Unrealized —

CYTK CYTOKINETICS INC 0.5%

Value $1.117M Shares 106,800 Est. Cost — Unrealized —

— MANNKIND CORP 0.3%

Value $729K Shares 503,000 Est. Cost — Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.1%

Value $214K Shares 151,611 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ADAMAS PHARMACEUTICALS INC	1,437,335	$40.7M	17.1%	$20.76	—	COM	00548A106
—	FIVE PRIME THERAPEUTICS INC	569,658	$23.64M	9.9%	$20.62	—	COM	33830X104
—	ZOGENIX INC	1,414,927	$20.86M	8.8%	$13.55	—	COM NEW	98978L204
VNDA	VANDA PHARMACEUTICALS INC	2,100,101	$19.55M	8.2%	$11.18	-10.8%	COM	921659108
—	TETRAPHASE PHARMACEUTICALS I	1,940,000	$19.46M	8.2%	$8.55	—	COM	88165N105
—	CONNECTURE INC	4,127,232	$14.9M	6.3%	$9.01	—	COM	20786J106
—	ALCOBRA LTD	2,012,622	$12.64M	5.3%	$5.99	—	SHS	M2239P109
EXEL	EXELIXIS, INC	2,032,494	$11.46M	4.8%	$5.47	+2.2%	COM	30161Q104
—	SYNERGY PHARMACEUTICALS DEL	1,546,888	$8.771M	3.7%	$7.60	—	COM NEW	871639308
—	SUNESIS PHARMACEUTICALS INC	8,250,000	$7.404M	3.1%	$1.47	—	COM NEW	867328601
—	GW PHARMACEUTICALS PLC	100,000	$6.944M	2.9%	—	—	Put	36197T103
—	PARATEK PHARMACEUTICALS INC	355,459	$6.743M	2.8%	$25.19	—	COM	699374302
—	RAPTOR PHARMACEUTICAL CORP	1,282,527	$6.669M	2.8%	$6.05	—	COM	75382F106
AUPH	AURINIA PHARMACEUTICALS INC	2,457,144	$6.16M	2.6%	$3.52	-23.0%	COM	05156V102
—	OCERA THERAPEUTICS INC	1,963,777	$6.127M	2.6%	$6.20	—	COM	67552A108
—	BOVIE MEDICAL CORP	2,680,000	$5.628M	2.4%	$2.72	—	COM	10211F100
VCEL	VERICEL CORP	2,086,028	$5.382M	2.3%	$2.85	-21.5%	COM	92346J108
—	ARADIGM CORP	1,002,962	$3.982M	1.7%	$8.85	—	COM NO PAR NEW	038505400
—	TENAX THERAPEUTICS INC	1,108,593	$3.636M	1.5%	$3.93	—	COM	88032L100
—	CALADRIUS BIOSCIENCES INC	2,248,781	$2.429M	1.0%	$1.87	—	COM	128058104
—	TRANSITION THERAPEUTICS INC	856,602	$1.645M	0.7%	$1.85	—	COM NEW	893716209
—	FLEXION THERAPEUTICS INC	78,100	$1.505M	0.6%	—	—	Call	33938J106
CYTK	CYTOKINETICS INC	106,800	$1.117M	0.5%	—	—	Put	23282W605
—	MANNKIND CORP	503,000	$729K	0.3%	—	—	Put	56400P201
—	STREAMLINE HEALTH SOLUTIONS	151,611	$214K	0.1%	$6.45	—	COM	86323X106