GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q1 2016 (← Previous) (Next →)

Filing Date: May 16, 2016

Total Value: $279M (100.0% shares, 0.0% debt)

Holdings (33)

— ADAMAS PHARMACEUTICALS INC 10.9%

Value $30.5M Shares 2,109,099 Est. Cost $18.75 Unrealized —

— FIVE PRIME THERAPEUTICS INC 8.4%

Value $23.36M Shares 575,000 Est. Cost $20.62 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 8.2%

Value $22.83M Shares 2,731,210 Est. Cost $10.50 Unrealized -21.8%

— ZOGENIX INC 6.9%

Value $19.27M Shares 2,085,959 Est. Cost $12.16 Unrealized —

— TETRAPHASE PHARMACEUTICALS I 6.1%

Value $16.91M Shares 3,653,200 Est. Cost $6.71 Unrealized —

— BLUEBIRD BIO INC 6.0%

Value $16.71M Shares 393,135 Est. Cost $42.50 Unrealized —

EXEL EXELIXIS INC 5.6%

Value $15.58M Shares 3,896,113 Est. Cost $4.88 Unrealized -13.3%

NBIX NEUROCRINE BIOSCIENCES INC 4.6%

Value $12.87M Shares 325,300 Est. Cost $39.68 Unrealized 0.0%

— INTERCEPT PHARMACEUTICALS IN 4.6%

Value $12.85M Shares 100,000 Est. Cost — Unrealized —

VCEL VERICEL CORP 4.4%

Value $12.37M Shares 2,110,738 Est. Cost $2.85 Unrealized -1.5%

— CONNECTURE INC 3.8%

Value $10.57M Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ALCOBRA LTD 2.7%

Value $7.656M Shares 2,020,166 Est. Cost $5.99 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 2.6%

Value $7.187M Shares 2,457,144 Est. Cost $3.52 Unrealized -31.4%

XNCR XENCOR INC 2.5%

Value $7.095M Shares 528,692 Est. Cost $11.83 Unrealized 0.0%

— AVALANCHE BIOTECHNOLOGIES IN 2.4%

Value $6.697M Shares 1,295,416 Est. Cost $5.17 Unrealized —

— CHIMERIX INC 2.4%

Value $6.643M Shares 1,300,000 Est. Cost $5.11 Unrealized —

— RAPTOR PHARMACEUTICAL CORP 2.2%

Value $6.193M Shares 1,346,344 Est. Cost $5.98 Unrealized —

— SYNERGY PHARMACEUTICALS DEL 2.2%

Value $6.003M Shares 2,175,000 Est. Cost $6.20 Unrealized —

— OCERA THERAPEUTICS INC 2.1%

Value $5.774M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— PARATEK PHARMACEUTICALS INC 1.7%

Value $4.634M Shares 305,459 Est. Cost $25.19 Unrealized —

— BOVIE MEDICAL CORP 1.6%

Value $4.476M Shares 2,680,000 Est. Cost $2.72 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.6%

Value $4.455M Shares 8,250,000 Est. Cost $1.47 Unrealized —

— ARADIGM CORP 1.6%

Value $4.453M Shares 1,002,962 Est. Cost $8.85 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 1.1%

Value $2.928M Shares 150,000 Est. Cost — Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 1.0%

Value $2.796M Shares 100,000 Est. Cost $21.84 Unrealized 0.0%

— TENAX THERAPEUTICS INC 0.8%

Value $2.273M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— IGNYTA INC 0.7%

Value $1.944M Shares 287,173 Est. Cost $6.77 Unrealized —

— CALADRIUS BIOSCIENCES INC 0.5%

Value $1.283M Shares 1,710,600 Est. Cost $1.87 Unrealized —

— PORTOLA PHARMACEUTICALS INC 0.4%

Value $1.02M Shares 50,000 Est. Cost $20.40 Unrealized —

— PORTOLA PHARMACEUTICALS INC 0.2%

Value $598K Shares 29,300 Est. Cost $20.40 Unrealized —

— RIGEL PHARMACEUTICALS INC 0.1%

Value $328K Shares 157,872 Est. Cost $2.08 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.1%

Value $214K Shares 151,611 Est. Cost $6.45 Unrealized —

— ATYR PHARMA INC 0.1%

Value $197K Shares 49,906 Est. Cost $3.95 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ADAMAS PHARMACEUTICALS INC	2,109,099	$30.5M	10.9%	$18.75	—	COM	00548A106
—	FIVE PRIME THERAPEUTICS INC	575,000	$23.36M	8.4%	$20.62	—	COM	33830X104
VNDA	VANDA PHARMACEUTICALS INC	2,731,210	$22.83M	8.2%	$10.50	-21.8%	COM	921659108
—	ZOGENIX INC	2,085,959	$19.27M	6.9%	$12.16	—	COM NEW	98978L204
—	TETRAPHASE PHARMACEUTICALS I	3,653,200	$16.91M	6.1%	$6.71	—	COM	88165N105
—	BLUEBIRD BIO INC	393,135	$16.71M	6.0%	$42.50	—	COM	09609G100
EXEL	EXELIXIS INC	3,896,113	$15.58M	5.6%	$4.88	-13.3%	COM	30161Q104
NBIX	NEUROCRINE BIOSCIENCES INC	325,300	$12.87M	4.6%	$39.68	0.0%	COM	64125C109
—	INTERCEPT PHARMACEUTICALS IN	100,000	$12.85M	4.6%	—	—	Put	45845P108
VCEL	VERICEL CORP	2,110,738	$12.37M	4.4%	$2.85	-1.5%	COM	92346J108
—	CONNECTURE INC	4,127,232	$10.57M	3.8%	$9.01	—	COM	20786J106
—	ALCOBRA LTD	2,020,166	$7.656M	2.7%	$5.99	—	SHS	M2239P109
AUPH	AURINIA PHARMACEUTICALS INC	2,457,144	$7.187M	2.6%	$3.52	-31.4%	COM	05156V102
XNCR	XENCOR INC	528,692	$7.095M	2.5%	$11.83	0.0%	COM	98401F105
—	AVALANCHE BIOTECHNOLOGIES IN	1,295,416	$6.697M	2.4%	$5.17	—	COM	05337G107
—	CHIMERIX INC	1,300,000	$6.643M	2.4%	$5.11	—	COM	16934W106
—	RAPTOR PHARMACEUTICAL CORP	1,346,344	$6.193M	2.2%	$5.98	—	COM	75382F106
—	SYNERGY PHARMACEUTICALS DEL	2,175,000	$6.003M	2.2%	$6.20	—	COM NEW	871639308
—	OCERA THERAPEUTICS INC	1,963,777	$5.774M	2.1%	$6.20	—	COM	67552A108
—	PARATEK PHARMACEUTICALS INC	305,459	$4.634M	1.7%	$25.19	—	COM	699374302
—	BOVIE MEDICAL CORP	2,680,000	$4.476M	1.6%	$2.72	—	COM	10211F100
—	SUNESIS PHARMACEUTICALS INC	8,250,000	$4.455M	1.6%	$1.47	—	COM NEW	867328601
—	ARADIGM CORP	1,002,962	$4.453M	1.6%	$8.85	—	COM NO PAR NEW	038505400
SRPT	SAREPTA THERAPEUTICS INC	150,000	$2.928M	1.1%	—	—	Call	803607100
ACAD	ACADIA PHARMACEUTICALS INC	100,000	$2.796M	1.0%	$21.84	0.0%	COM	004225108
—	TENAX THERAPEUTICS INC	1,108,593	$2.273M	0.8%	$3.93	—	COM	88032L100
—	IGNYTA INC	287,173	$1.944M	0.7%	$6.77	—	COM	451731103
—	CALADRIUS BIOSCIENCES INC	1,710,600	$1.283M	0.5%	$1.87	—	COM	128058104
—	PORTOLA PHARMACEUTICALS INC	50,000	$1.02M	0.4%	$20.40	—	COM	737010108
—	PORTOLA PHARMACEUTICALS INC	29,300	$598K	0.2%	$20.40	—	Call	737010108
—	RIGEL PHARMACEUTICALS INC	157,872	$328K	0.1%	$2.08	—	COM NEW	766559603
—	STREAMLINE HEALTH SOLUTIONS	151,611	$214K	0.1%	$6.45	—	COM	86323X106
—	ATYR PHARMA INC	49,906	$197K	0.1%	$3.95	—	COM	002120103