GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2016 (← Previous) (Next →)

Filing Date: Aug 15, 2016

Total Value: $349M (100.0% shares, 0.0% debt)

Holdings (39)

— ADAMAS PHARMACEUTICALS INC 9.1%

Value $31.93M Shares 2,109,099 Est. Cost $18.75 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 8.7%

Value $30.28M Shares 2,705,758 Est. Cost $10.50 Unrealized -7.7%

— SYNERGY PHARMACEUTICALS DEL 8.3%

Value $28.84M Shares 7,590,000 Est. Cost $4.49 Unrealized —

EXEL EXELIXIS INC 7.2%

Value $24.99M Shares 3,200,000 Est. Cost $4.88 Unrealized +18.1%

— DERMIRA INC 6.7%

Value $23.4M Shares 800,000 Est. Cost $29.25 Unrealized —

— BLUEBIRD BIO INC 6.2%

Value $21.64M Shares 500,000 Est. Cost $42.67 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 6.1%

Value $21.36M Shares 470,000 Est. Cost $41.64 Unrealized +10.6%

EGRX EAGLE PHARMACEUTICALS INC 6.1%

Value $21.27M Shares 548,290 Est. Cost $41.64 Unrealized 0.0%

— ZOGENIX INC 5.6%

Value $19.65M Shares 2,440,959 Est. Cost $11.56 Unrealized —

— IGNYTA INC 5.0%

Value $17.55M Shares 3,238,703 Est. Cost $5.54 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 3.4%

Value $11.86M Shares 538,024 Est. Cost $26.18 Unrealized 0.0%

— SAGE THERAPEUTICS INC 2.8%

Value $9.943M Shares 330,000 Est. Cost $30.13 Unrealized —

— TETRAPHASE PHARMACEUTICALS I 2.8%

Value $9.888M Shares 2,299,529 Est. Cost $6.71 Unrealized —

— CONNECTURE INC 2.7%

Value $9.328M Shares 4,127,232 Est. Cost $9.01 Unrealized —

XNCR XENCOR INC 2.4%

Value $8.546M Shares 450,000 Est. Cost $11.83 Unrealized +15.9%

AUPH AURINIA PHARMACEUTICALS INC 2.1%

Value $7.192M Shares 2,457,144 Est. Cost $3.52 Unrealized -22.5%

— ALCOBRA LTD 1.8%

Value $6.351M Shares 1,414,573 Est. Cost $5.99 Unrealized —

— RAPTOR PHARMACEUTICAL CORP 1.5%

Value $5.254M Shares 978,350 Est. Cost $5.98 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 1.3%

Value $4.556M Shares 238,900 Est. Cost — Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.3%

Value $4.477M Shares 8,173,937 Est. Cost $1.47 Unrealized —

— BOVIE MEDICAL CORP 1.3%

Value $4.395M Shares 2,680,000 Est. Cost $2.72 Unrealized —

— ARADIGM CORP 1.3%

Value $4.383M Shares 1,002,962 Est. Cost $8.85 Unrealized —

— INTRA CELLULAR THERAPIES INC 1.1%

Value $3.882M Shares 100,000 Est. Cost $38.82 Unrealized —

— OCERA THERAPEUTICS INC 1.1%

Value $3.731M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— SERES THERAPEUTICS INC 1.0%

Value $3.486M Shares 120,000 Est. Cost — Unrealized —

— TENAX THERAPEUTICS INC 0.8%

Value $2.838M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 0.5%

Value $1.745M Shares 274,756 Est. Cost $6.35 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 0.5%

Value $1.738M Shares 550,116 Est. Cost $3.16 Unrealized —

ASND ASCENDIS PHARMA A S 0.3%

Value $1.015M Shares 76,511 Est. Cost $13.27 Unrealized —

— CALADRIUS BIOSCIENCES INC 0.3%

Value $900K Shares 1,525,244 Est. Cost $1.87 Unrealized —

— DIPEXIUM PHARMACEUTICALS INC 0.2%

Value $871K Shares 87,914 Est. Cost $9.91 Unrealized —

VCEL VERICEL CORP 0.2%

Value $570K Shares 253,502 Est. Cost $2.85 Unrealized +1.3%

— PARATEK PHARMACEUTICALS INC 0.1%

Value $407K Shares 29,266 Est. Cost $25.19 Unrealized —

— AXOVANT SCIENCES LTD 0.1%

Value $321K Shares 25,000 Est. Cost $12.84 Unrealized —

— REVANCE THERAPEUTICS INC 0.1%

Value $295K Shares 21,665 Est. Cost $13.62 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.1%

Value $182K Shares 151,611 Est. Cost $6.45 Unrealized —

— RIGEL PHARMACEUTICALS INC 0.0%

Value $112K Shares 50,000 Est. Cost $2.08 Unrealized —

ARDX ARDELYX INC 0.0%

Value $30,000 Shares 3,444 Est. Cost $8.17 Unrealized 0.0%

— AMARIN CORP PLC 0.0%

Value $4,000 Shares 2,000 Est. Cost $2.00 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ADAMAS PHARMACEUTICALS INC	2,109,099	$31.93M	9.1%	$18.75	—	COM	00548A106
VNDA	VANDA PHARMACEUTICALS INC	2,705,758	$30.28M	8.7%	$10.50	-7.7%	COM	921659108
—	SYNERGY PHARMACEUTICALS DEL	7,590,000	$28.84M	8.3%	$4.49	—	COM NEW	871639308
EXEL	EXELIXIS INC	3,200,000	$24.99M	7.2%	$4.88	+18.1%	COM	30161Q104
—	DERMIRA INC	800,000	$23.4M	6.7%	$29.25	—	COM	24983L104
—	BLUEBIRD BIO INC	500,000	$21.64M	6.2%	$42.67	—	COM	09609G100
NBIX	NEUROCRINE BIOSCIENCES INC	470,000	$21.36M	6.1%	$41.64	+10.6%	COM	64125C109
EGRX	EAGLE PHARMACEUTICALS INC	548,290	$21.27M	6.1%	$41.64	0.0%	COM	269796108
—	ZOGENIX INC	2,440,959	$19.65M	5.6%	$11.56	—	COM NEW	98978L204
—	IGNYTA INC	3,238,703	$17.55M	5.0%	$5.54	—	COM	451731103
ENTA	ENANTA PHARMACEUTICALS INC	538,024	$11.86M	3.4%	$26.18	0.0%	COM	29251M106
—	SAGE THERAPEUTICS INC	330,000	$9.943M	2.8%	$30.13	—	COM	78667J108
—	TETRAPHASE PHARMACEUTICALS I	2,299,529	$9.888M	2.8%	$6.71	—	COM	88165N105
—	CONNECTURE INC	4,127,232	$9.328M	2.7%	$9.01	—	COM	20786J106
XNCR	XENCOR INC	450,000	$8.546M	2.4%	$11.83	+15.9%	COM	98401F105
AUPH	AURINIA PHARMACEUTICALS INC	2,457,144	$7.192M	2.1%	$3.52	-22.5%	COM	05156V102
—	ALCOBRA LTD	1,414,573	$6.351M	1.8%	$5.99	—	SHS	M2239P109
—	RAPTOR PHARMACEUTICAL CORP	978,350	$5.254M	1.5%	$5.98	—	COM	75382F106
SRPT	SAREPTA THERAPEUTICS INC	238,900	$4.556M	1.3%	—	—	Call	803607100
—	SUNESIS PHARMACEUTICALS INC	8,173,937	$4.477M	1.3%	$1.47	—	COM NEW	867328601
—	BOVIE MEDICAL CORP	2,680,000	$4.395M	1.3%	$2.72	—	COM	10211F100
—	ARADIGM CORP	1,002,962	$4.383M	1.3%	$8.85	—	COM NO PAR NEW	038505400
—	INTRA CELLULAR THERAPIES INC	100,000	$3.882M	1.1%	$38.82	—	COM	46116X101
—	OCERA THERAPEUTICS INC	1,963,777	$3.731M	1.1%	$6.20	—	COM	67552A108
—	SERES THERAPEUTICS INC	120,000	$3.486M	1.0%	—	—	Put	81750R102
—	TENAX THERAPEUTICS INC	1,108,593	$2.838M	0.8%	$3.93	—	COM	88032L100
—	FOAMIX PHARMACEUTICALS LTD	274,756	$1.745M	0.5%	$6.35	—	SHS	M46135105
—	ADVERUM BIOTECHNOLOGIES INC	550,116	$1.738M	0.5%	$3.16	—	COM	00773U108
ASND	ASCENDIS PHARMA A S	76,511	$1.015M	0.3%	$13.27	—	SPONSORED ADR	04351P101
—	CALADRIUS BIOSCIENCES INC	1,525,244	$900K	0.3%	$1.87	—	COM	128058104
—	DIPEXIUM PHARMACEUTICALS INC	87,914	$871K	0.2%	$9.91	—	COM	25456J104
VCEL	VERICEL CORP	253,502	$570K	0.2%	$2.85	+1.3%	COM	92346J108
—	PARATEK PHARMACEUTICALS INC	29,266	$407K	0.1%	$25.19	—	COM	699374302
—	AXOVANT SCIENCES LTD	25,000	$321K	0.1%	$12.84	—	COM	G0750W104
—	REVANCE THERAPEUTICS INC	21,665	$295K	0.1%	$13.62	—	COM	761330109
—	STREAMLINE HEALTH SOLUTIONS	151,611	$182K	0.1%	$6.45	—	COM	86323X106
—	RIGEL PHARMACEUTICALS INC	50,000	$112K	0.0%	$2.08	—	COM NEW	766559603
ARDX	ARDELYX INC	3,444	$30,000	0.0%	$8.17	0.0%	COM	039697107
—	AMARIN CORP PLC	2,000	$4,000	0.0%	$2.00	—	SPON ADR NEW	023111206