GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q3 2016 (← Previous) (Next →)

Filing Date: Nov 14, 2016

Total Value ($000): $392,073 (100.0% shares, 0.0% debt)

Holdings (35)

VNDA VANDA PHARMACEUTICALS INC. CMN 11.5%

Value ($000) $45,030 Shares 2,706,134 Est. Cost $10.50 Unrealized +28.3%

— ADAMAS PHARMACEUTICALS INC CMN 10.9%

Value ($000) $42,688 Shares 2,601,351 Est. Cost $18.31 Unrealized —

— SYNERGY PHARMACEUTICALS INC CMN 9.0%

Value ($000) $35,386 Shares 6,422,232 Est. Cost $4.49 Unrealized —

— ZOGENIX INC CMN 7.1%

Value ($000) $27,900 Shares 2,440,959 Est. Cost $11.56 Unrealized —

— FOAMIX PHARMACEUTICALS LIMITED CMN 6.5%

Value ($000) $25,645 Shares 2,769,425 Est. Cost $8.97 Unrealized —

— DERMIRA INC CMN 5.9%

Value ($000) $22,977 Shares 679,403 Est. Cost $29.25 Unrealized —

— IGNYTA INC CMN 5.6%

Value ($000) $21,859 Shares 3,475,227 Est. Cost $5.59 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC CMN 5.4%

Value ($000) $21,022 Shares 790,000 Est. Cost $25.23 Unrealized -8.0%

NBIX NEUROCRINE BIOSCIENCES INC CMN 5.1%

Value ($000) $19,956 Shares 394,080 Est. Cost $41.64 Unrealized +19.6%

— AVEXIS INC CMN 4.0%

Value ($000) $15,703 Shares 381,095 Est. Cost $41.20 Unrealized —

— MERRIMACK PHARMACEUTICALS INC CMN 4.0%

Value ($000) $15,508 Shares 2,442,159 Est. Cost $6.35 Unrealized —

— COLUCID PHARMACEUTICALS INC CMN 3.9%

Value ($000) $15,260 Shares 400,000 Est. Cost $38.15 Unrealized —

— BOVIE MEDICAL CORPORATION CMN 3.6%

Value ($000) $13,963 Shares 2,680,000 Est. Cost $2.72 Unrealized —

— SAGE THERAPEUTICS, INC CMN 3.1%

Value ($000) $12,198 Shares 264,893 Est. Cost $30.13 Unrealized —

— CONNECTURE INC 2.0%

Value ($000) $7,759 Shares 4,127,232 Est. Cost $9.01 Unrealized —

— ARADIGM CORP CMN 1.8%

Value ($000) $6,900 Shares 1,002,962 Est. Cost $8.85 Unrealized —

— OCERA THERAPEUTICS INC CMN CLASS 1.3%

Value ($000) $5,184 Shares 1,963,777 Est. Cost $6.20 Unrealized —

— DBV TECHNOLOGIES SA SPONSORED ADR CMN 1.2%

Value ($000) $4,776 Shares 131,452 Est. Cost $36.33 Unrealized —

— SUNESIS PHARMACEUTICALS INC CMN 1.2%

Value ($000) $4,648 Shares 1,063,573 Est. Cost $4.37 Unrealized —

— ALIMERA SCIENCES CMN 1.0%

Value ($000) $3,931 Shares 2,637,969 Est. Cost $1.49 Unrealized —

BCRX PUT/BCRX @ 5 EXP 03/17/2017 0.8%

Value ($000) $3,197 Shares 725,000 Est. Cost — Unrealized —

— PUT/GWPH @ 95 EXP 10/21/2016 0.8%

Value ($000) $3,159 Shares 23,800 Est. Cost — Unrealized —

— DIPEXIUM PHARMACEUTICALS INC CMN 0.7%

Value ($000) $2,594 Shares 178,930 Est. Cost $12.24 Unrealized —

— TENAX THERAPEUTICS INC CMN 0.7%

Value ($000) $2,568 Shares 1,108,593 Est. Cost $3.93 Unrealized —

— PDL BIOPHARMA INC CMN 0.6%

Value ($000) $2,161 Shares 645,000 Est. Cost $3.35 Unrealized —

— TETRAPHASE PHARMACEUTICALS INC CMN 0.4%

Value ($000) $1,733 Shares 452,375 Est. Cost $6.71 Unrealized —

— CATABASIS PHARMACEUTICALS, INC CMN 0.4%

Value ($000) $1,540 Shares 250,000 Est. Cost $6.16 Unrealized —

— MIRATI THERAPEUTICS INC CMN 0.4%

Value ($000) $1,505 Shares 227,657 Est. Cost $6.61 Unrealized —

— SERES THERAPEUTICS, INC. CMN 0.4%

Value ($000) $1,475 Shares 120,000 Est. Cost $12.29 Unrealized —

— PUT/MCRB @ 20 EXP 10/21/2016 0.4%

Value ($000) $1,475 Shares 120,000 Est. Cost $12.29 Unrealized —

— INOTEK PHARMACEUTICALS CORP CMN 0.2%

Value ($000) $892 Shares 94,077 Est. Cost $9.48 Unrealized —

— CALL/NVAX @ 8 EXP 10/21/2016 0.2%

Value ($000) $851 Shares 409,200 Est. Cost — Unrealized —

— STREAMLINE HEALTH SOLUTNS, INC CMN 0.1%

Value ($000) $279 Shares 151,611 Est. Cost $6.45 Unrealized —

ARDX ARDELYX INC CMN 0.0%

Value ($000) $194 Shares 15,000 Est. Cost $9.95 Unrealized +5.3%

— CALL/OPHT @ 80 EXP 01/20/2017 0.0%

Value ($000) $157 Shares 3,400 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
VNDA	VANDA PHARMACEUTICALS INC. CMN	2,706,134	$45,030	11.5%	$10.50	+28.3%	COM	921659108
—	ADAMAS PHARMACEUTICALS INC CMN	2,601,351	$42,688	10.9%	$18.31	—	COM	00548A106
—	SYNERGY PHARMACEUTICALS INC CMN	6,422,232	$35,386	9.0%	$4.49	—	COM	871639308
—	ZOGENIX INC CMN	2,440,959	$27,900	7.1%	$11.56	—	COM	98978L204
—	FOAMIX PHARMACEUTICALS LIMITED CMN	2,769,425	$25,645	6.5%	$8.97	—	COM	M46135105
—	DERMIRA INC CMN	679,403	$22,977	5.9%	$29.25	—	COM	24983L104
—	IGNYTA INC CMN	3,475,227	$21,859	5.6%	$5.59	—	COM	451731103
ENTA	ENANTA PHARMACEUTICALS INC CMN	790,000	$21,022	5.4%	$25.23	-8.0%	COM	29251M106
NBIX	NEUROCRINE BIOSCIENCES INC CMN	394,080	$19,956	5.1%	$41.64	+19.6%	COM	64125C109
—	AVEXIS INC CMN	381,095	$15,703	4.0%	$41.20	—	COM	05366U100
—	MERRIMACK PHARMACEUTICALS INC CMN	2,442,159	$15,508	4.0%	$6.35	—	COM	590328100
—	COLUCID PHARMACEUTICALS INC CMN	400,000	$15,260	3.9%	$38.15	—	COM	19716T101
—	BOVIE MEDICAL CORPORATION CMN	2,680,000	$13,963	3.6%	$2.72	—	COM	10211F100
—	SAGE THERAPEUTICS, INC CMN	264,893	$12,198	3.1%	$30.13	—	COM	78667J108
—	CONNECTURE INC	4,127,232	$7,759	2.0%	$9.01	—	COM	20786J106
—	ARADIGM CORP CMN	1,002,962	$6,900	1.8%	$8.85	—	COM	038505400
—	OCERA THERAPEUTICS INC CMN CLASS	1,963,777	$5,184	1.3%	$6.20	—	COM	67552A108
—	DBV TECHNOLOGIES SA SPONSORED ADR CMN	131,452	$4,776	1.2%	$36.33	—	COM	23306J101
—	SUNESIS PHARMACEUTICALS INC CMN	1,063,573	$4,648	1.2%	$4.37	—	COM	867328700
—	ALIMERA SCIENCES CMN	2,637,969	$3,931	1.0%	$1.49	—	COM	016259103
BCRX	PUT/BCRX @ 5 EXP 03/17/2017	725,000	$3,197	0.8%	—	—	Put	09058V103
—	PUT/GWPH @ 95 EXP 10/21/2016	23,800	$3,159	0.8%	—	—	Put	36197T103
—	DIPEXIUM PHARMACEUTICALS INC CMN	178,930	$2,594	0.7%	$12.24	—	COM	25456J104
—	TENAX THERAPEUTICS INC CMN	1,108,593	$2,568	0.7%	$3.93	—	COM	88032L100
—	PDL BIOPHARMA INC CMN	645,000	$2,161	0.6%	$3.35	—	COM	69329Y104
—	TETRAPHASE PHARMACEUTICALS INC CMN	452,375	$1,733	0.4%	$6.71	—	COM	88165N105
—	CATABASIS PHARMACEUTICALS, INC CMN	250,000	$1,540	0.4%	$6.16	—	COM	14875P107
—	MIRATI THERAPEUTICS INC CMN	227,657	$1,505	0.4%	$6.61	—	COM	60468T105
—	SERES THERAPEUTICS, INC. CMN	120,000	$1,475	0.4%	$12.29	—	COM	81750R102
—	PUT/MCRB @ 20 EXP 10/21/2016	120,000	$1,475	0.4%	$12.29	—	Put	81750R102
—	INOTEK PHARMACEUTICALS CORP CMN	94,077	$892	0.2%	$9.48	—	COM	45780V102
—	CALL/NVAX @ 8 EXP 10/21/2016	409,200	$851	0.2%	—	—	Call	670002104
—	STREAMLINE HEALTH SOLUTNS, INC CMN	151,611	$279	0.1%	$6.45	—	COM	86323X106
ARDX	ARDELYX INC CMN	15,000	$194	0.0%	$9.95	+5.3%	COM	039697107
—	CALL/OPHT @ 80 EXP 01/20/2017	3,400	$157	0.0%	—	—	Call	683745103