GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q4 2016 (← Previous) (Next →)

Filing Date: Feb 14, 2017

Total Value: $487M (100.0% shares, 0.0% debt)

Holdings (35)

— ADAMAS PHARMACEUTICALS INC 9.0%

Value $43.96M Shares 2,601,351 Est. Cost $18.31 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 6.8%

Value $33.3M Shares 3,000,000 Est. Cost $9.14 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 6.6%

Value $32.06M Shares 2,010,000 Est. Cost $10.50 Unrealized +53.1%

— SYNERGY PHARMACEUTICALS DEL 6.2%

Value $30.29M Shares 4,973,509 Est. Cost $4.49 Unrealized —

— ZOGENIX INC 6.1%

Value $29.66M Shares 2,440,959 Est. Cost $11.56 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 6.0%

Value $29.02M Shares 750,000 Est. Cost $43.36 Unrealized +4.4%

ENTA ENANTA PHARMACEUTICALS INC 5.7%

Value $27.75M Shares 828,253 Est. Cost $25.39 Unrealized +12.9%

— MEDICINES CO 5.2%

Value $25.45M Shares 750,000 Est. Cost — Unrealized —

— IGNYTA INC 4.4%

Value $21.2M Shares 4,000,000 Est. Cost $5.55 Unrealized —

— MERRIMACK PHARMACEUTICALS INC 4.2%

Value $20.4M Shares 5,000,000 Est. Cost $5.19 Unrealized —

— AVEXIS INC 4.1%

Value $19.72M Shares 413,179 Est. Cost $41.71 Unrealized —

— SAGE THERAPEUTICS INC 4.0%

Value $19.69M Shares 385,683 Est. Cost $36.69 Unrealized —

— THERAPEUTICSMD INC 3.9%

Value $18.9M Shares 3,276,010 Est. Cost $5.77 Unrealized —

— TREVENA INC 3.6%

Value $17.64M Shares 3,000,650 Est. Cost $5.88 Unrealized —

— COLUCID PHARMACEUTICALS INC 3.3%

Value $15.94M Shares 437,865 Est. Cost $38.00 Unrealized —

— GLOBAL BLOOD THERAPEUTICS INC 3.0%

Value $14.45M Shares 1,000,000 Est. Cost $14.45 Unrealized —

— DBV TECHNOLOGIES S A 2.7%

Value $13M Shares 370,000 Est. Cost $35.56 Unrealized —

— BOVIE MEDICAL CORP 2.3%

Value $10.97M Shares 3,055,000 Est. Cost $2.83 Unrealized —

— INOTEK PHARMACEUTICALS CORP 1.9%

Value $9.15M Shares 1,500,000 Est. Cost $6.31 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 1.6%

Value $7.787M Shares 270,000 Est. Cost $26.46 Unrealized 0.0%

— CONNECTURE INC 1.4%

Value $6.934M Shares 4,127,232 Est. Cost $9.01 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.1%

Value $5.567M Shares 1,537,873 Est. Cost $4.14 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 0.9%

Value $4.589M Shares 725,000 Est. Cost — Unrealized —

— MYOVANT SCIENCES LTD 0.9%

Value $4.354M Shares 350,000 Est. Cost $12.44 Unrealized —

— MIRATI THERAPEUTICS INC 0.8%

Value $4.134M Shares 870,261 Est. Cost $5.24 Unrealized —

— OCERA THERAPEUTICS INC 0.8%

Value $4.124M Shares 1,963,777 Est. Cost $6.20 Unrealized —

— DERMIRA INC 0.7%

Value $3.46M Shares 114,080 Est. Cost $29.25 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 0.7%

Value $3.165M Shares 500,000 Est. Cost — Unrealized —

— ALIMERA SCIENCES INC 0.5%

Value $2.477M Shares 2,293,675 Est. Cost $1.49 Unrealized —

— TENAX THERAPEUTICS INC 0.4%

Value $2.162M Shares 1,108,593 Est. Cost $3.93 Unrealized —

— CATABASIS PHARMACEUTICALS INC 0.4%

Value $2.009M Shares 556,537 Est. Cost $4.76 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 0.4%

Value $1.944M Shares 51,935 Est. Cost $41.87 Unrealized 0.0%

— ARADIGM CORP 0.3%

Value $1.267M Shares 791,870 Est. Cost $8.85 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.0%

Value $190K Shares 151,611 Est. Cost $6.45 Unrealized —

— OPHTHOTECH CORP 0.0%

Value $34,000 Shares 7,100 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ADAMAS PHARMACEUTICALS INC	2,601,351	$43.96M	9.0%	$18.31	—	COM	00548A106
—	FOAMIX PHARMACEUTICALS LTD	3,000,000	$33.3M	6.8%	$9.14	—	SHS	M46135105
VNDA	VANDA PHARMACEUTICALS INC	2,010,000	$32.06M	6.6%	$10.50	+53.1%	COM	921659108
—	SYNERGY PHARMACEUTICALS DEL	4,973,509	$30.29M	6.2%	$4.49	—	COM NEW	871639308
—	ZOGENIX INC	2,440,959	$29.66M	6.1%	$11.56	—	COM NEW	98978L204
NBIX	NEUROCRINE BIOSCIENCES INC	750,000	$29.02M	6.0%	$43.36	+4.4%	COM	64125C109
ENTA	ENANTA PHARMACEUTICALS INC	828,253	$27.75M	5.7%	$25.39	+12.9%	COM	29251M106
—	MEDICINES CO	750,000	$25.45M	5.2%	—	—	Put	584688105
—	IGNYTA INC	4,000,000	$21.2M	4.4%	$5.55	—	COM	451731103
—	MERRIMACK PHARMACEUTICALS INC	5,000,000	$20.4M	4.2%	$5.19	—	COM	590328100
—	AVEXIS INC	413,179	$19.72M	4.1%	$41.71	—	COM	05366U100
—	SAGE THERAPEUTICS INC	385,683	$19.69M	4.0%	$36.69	—	COM	78667J108
—	THERAPEUTICSMD INC	3,276,010	$18.9M	3.9%	$5.77	—	COM	88338N107
—	TREVENA INC	3,000,650	$17.64M	3.6%	$5.88	—	COM	89532E109
—	COLUCID PHARMACEUTICALS INC	437,865	$15.94M	3.3%	$38.00	—	COM	19716T101
—	GLOBAL BLOOD THERAPEUTICS INC	1,000,000	$14.45M	3.0%	$14.45	—	COM	37890U108
—	DBV TECHNOLOGIES S A	370,000	$13M	2.7%	$35.56	—	SPONSORED ADR	23306J101
—	BOVIE MEDICAL CORP	3,055,000	$10.97M	2.3%	$2.83	—	COM	10211F100
—	INOTEK PHARMACEUTICALS CORP	1,500,000	$9.15M	1.9%	$6.31	—	COM	45780V102
ACAD	ACADIA PHARMACEUTICALS INC	270,000	$7.787M	1.6%	$26.46	0.0%	COM	004225108
—	CONNECTURE INC	4,127,232	$6.934M	1.4%	$9.01	—	COM	20786J106
—	SUNESIS PHARMACEUTICALS INC	1,537,873	$5.567M	1.1%	$4.14	—	COM PAR	867328700
BCRX	BIOCRYST PHARMACEUTICALS	725,000	$4.589M	0.9%	—	—	Put	09058V103
—	MYOVANT SCIENCES LTD	350,000	$4.354M	0.9%	$12.44	—	COM	G637AM102
—	MIRATI THERAPEUTICS INC	870,261	$4.134M	0.8%	$5.24	—	COM	60468T105
—	OCERA THERAPEUTICS INC	1,963,777	$4.124M	0.8%	$6.20	—	COM	67552A108
—	DERMIRA INC	114,080	$3.46M	0.7%	$29.25	—	COM	24983L104
BCRX	BIOCRYST PHARMACEUTICALS	500,000	$3.165M	0.7%	—	—	Call	09058V103
—	ALIMERA SCIENCES INC	2,293,675	$2.477M	0.5%	$1.49	—	COM	016259103
—	TENAX THERAPEUTICS INC	1,108,593	$2.162M	0.4%	$3.93	—	COM	88032L100
—	CATABASIS PHARMACEUTICALS INC	556,537	$2.009M	0.4%	$4.76	—	COM	14875P107
ALNY	ALNYLAM PHARMACEUTICALS INC	51,935	$1.944M	0.4%	$41.87	0.0%	COM	02043Q107
—	ARADIGM CORP	791,870	$1.267M	0.3%	$8.85	—	COM NO PAR VALUE	038505400
—	STREAMLINE HEALTH SOLUTIONS	151,611	$190K	0.0%	$6.45	—	COM	86323X106
—	OPHTHOTECH CORP	7,100	$34,000	0.0%	—	—	Call	683745103