EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 15, 2025

Total Value ($000): $1,686,023 (100.0% shares, 0.0% debt)

Holdings (46)

APLS APELLIS PHARMACEUTICALS INC 15.4%
Value ($000) $260,161 Shares 11,895,808 Est. Cost $43.04 Unrealized -35.8%
JAZZ JAZZ PHARMACEUTICALS PLC 12.6%
Value ($000) $211,858 Shares 1,706,469 Est. Cost $120.72 Unrealized +8.1%
ZYME ZYMEWORKS INC 12.2%
Value ($000) $205,561 Shares 17,259,548 Est. Cost $9.14 Unrealized +49.1%
ANAB ANAPTYSBIO INC 8.7%
Value ($000) $146,491 Shares 7,880,094 Est. Cost $23.54 Unrealized -29.1%
CRNX CRINETICS PHARMACEUTICALS IN 8.5%
Value ($000) $143,824 Shares 4,288,120 Est. Cost $32.41 Unrealized +15.2%
PRTA PROTHENA CORP PLC 8.5%
Value ($000) $143,355 Shares 11,584,280 Est. Cost $11.63 Unrealized +21.5%
SRPT SAREPTA THERAPEUTICS INC 4.9%
Value ($000) $82,480 Shares 1,292,386 Est. Cost $115.57 Unrealized -8.9%
XNCR XENCOR INC 3.9%
Value ($000) $65,380 Shares 6,144,767 Est. Cost $32.11 Unrealized -48.5%
CRSP CRISPR THERAPEUTICS AG 2.8%
Value ($000) $47,277 Shares 1,389,276 Est. Cost $71.59 Unrealized -40.8%
QURE UNIQURE NV 2.5%
Value ($000) $42,283 Shares 3,988,971 Est. Cost $9.43 Unrealized +48.7%
JANX JANUX THERAPEUTICS INC 2.4%
Value ($000) $39,685 Shares 1,469,818 Est. Cost $46.95 Unrealized -19.7%
IMNM IMMUNOME INC 1.6%
Value ($000) $27,454 Shares 4,079,415 Est. Cost $8.38 Unrealized +14.5%
ETON ETON PHARMACEUTICALS INC 1.5%
Value ($000) $25,172 Shares 1,939,288 Est. Cost $8.70 Unrealized +73.8%
MDGL MADRIGAL PHARMACEUTICALS INC 1.5%
Value ($000) $24,842 Shares 75,000 Est. Cost $235.62 Unrealized +39.5%
ORIC ORIC PHARMACEUTICALS INC 1.1%
Value ($000) $19,073 Shares 3,418,068 Est. Cost $30.24 Unrealized -71.1%
— AKERO THERAPEUTICS INC 1.1%
Value ($000) $17,811 Shares 440,000 Est. Cost $40.48 Unrealized —
KURA KURA ONCOLOGY INC 1.0%
Value ($000) $17,426 Shares 2,640,298 Est. Cost $18.76 Unrealized -58.5%
TECX TECTONIC THERAPEUTIC INC 1.0%
Value ($000) $16,561 Shares 935,121 Est. Cost $17.32 Unrealized +88.2%
RNAM AVIDITY BIOSCIENCES INC 1.0%
Value ($000) $16,460 Shares 557,576 Est. Cost $15.67 Unrealized +98.7%
NGNE NEUROGENE INC 0.9%
Value ($000) $14,887 Shares 1,271,342 Est. Cost $14.32 Unrealized +21.3%
TNGX TANGO THERAPEUTICS INC 0.9%
Value ($000) $14,564 Shares 10,630,736 Est. Cost $7.06 Unrealized -65.2%
VYGR VOYAGER THERAPEUTICS INC 0.8%
Value ($000) $13,241 Shares 3,917,546 Est. Cost $3.61 Unrealized —
BEAM BEAM THERAPEUTICS INC 0.6%
Value ($000) $10,286 Shares 526,685 Est. Cost $26.20 Unrealized 0.0%
MBX MBX BIOSCIENCES INC 0.6%
Value ($000) $9,293 Shares 1,259,273 Est. Cost $22.77 Unrealized -53.6%
DNA GINKGO BIOWORKS HOLDINGS INC 0.5%
Value ($000) $8,335 Shares 1,462,328 Est. Cost $8.57 Unrealized +18.9%
REPL REPLIMUNE GROUP INC 0.5%
Value ($000) $8,291 Shares 850,341 Est. Cost $6.97 Unrealized +77.6%
BCYC BICYCLE THERAPEUTICS PLC 0.5%
Value ($000) $7,726 Shares 910,000 Est. Cost $20.24 Unrealized —
DAWN DAY ONE BIOPHARMACEUTICALS I 0.4%
Value ($000) $6,836 Shares 862,068 Est. Cost $14.27 Unrealized -24.5%
— VERVE THERAPEUTICS INC 0.3%
Value ($000) $5,713 Shares 1,250,000 Est. Cost $13.94 Unrealized —
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.3%
Value ($000) $5,399 Shares 27,404,070 Est. Cost $1.58 Unrealized —
GLPG GALAPAGOS NV 0.2%
Value ($000) $3,894 Shares 155,006 Est. Cost $49.34 Unrealized —
WHWK WHITEHAWK THERAPEUTICS INC 0.2%
Value ($000) $3,706 Shares 2,082,000 Est. Cost $2.45 Unrealized +6.7%
ATRA ATARA BIOTHERAPEUTICS INC 0.2%
Value ($000) $3,405 Shares 573,183 Est. Cost $13.39 Unrealized -34.8%
SLDB SOLID BIOSCIENCES INC 0.2%
Value ($000) $2,754 Shares 744,450 Est. Cost $4.28 Unrealized 0.0%
KROS KEROS THERAPEUTICS INC 0.1%
Value ($000) $1,911 Shares 187,500 Est. Cost $59.30 Unrealized -80.4%
— NUVATION BIO INC 0.1%
Value ($000) $1,695 Shares 963,333 Est. Cost $10.45 Unrealized —
RLAY RELAY THERAPEUTICS INC 0.1%
Value ($000) $1,681 Shares 641,426 Est. Cost $7.47 Unrealized -47.6%
KLRS KALARIS THERAPEUTICS INC 0.1%
Value ($000) $1,620 Shares 201,718 Est. Cost $9.79 Unrealized 0.0%
QURE UNIQURE NV 0.1%
Value ($000) $1,431 Shares 135,000 Est. Cost $9.43 Unrealized +48.7%
PRME PRIME MEDICINE INC 0.1%
Value ($000) $1,393 Shares 700,000 Est. Cost $7.58 Unrealized -66.4%
— METSERA INC 0.1%
Value ($000) $1,361 Shares 50,000 Est. Cost $27.22 Unrealized —
TCRX TSCAN THERAPEUTICS INC 0.1%
Value ($000) $915 Shares 662,833 Est. Cost $2.68 Unrealized -19.3%
SRZNW SURROZEN INC 0.0%
Value ($000) $777 Shares 66,665 Est. Cost $7.07 Unrealized —
ALGS ALIGOS THERAPEUTICS INC 0.0%
Value ($000) $731 Shares 88,569 Est. Cost $12.44 Unrealized +76.2%
ETON ETON PHARMACEUTICALS INC 0.0%
Value ($000) $655 Shares 50,500 Est. Cost $8.70 Unrealized +73.8%
UPB UPSTREAM BIO INC 0.0%
Value ($000) $367 Shares 60,000 Est. Cost $22.33 Unrealized -57.2%