Location: San Francisco, CA
CIK: 0001587114 · Show all filings
Period: Q4 2024 (← Previous) (Next →)
Filing Date: Feb 14, 2025
Total Value: $2.645B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| APLS | APELLIS PHARMACEUTICALS INC | 11,890,843 | $379M | 14.3% | $43.04 | -30.1% | COM | 03753U106 |
| ZYME | ZYMEWORKS INC | 15,028,079 | $220M | 8.3% | $8.48 | +65.0% | COM | 98985Y108 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 4,288,120 | $219M | 8.3% | $32.41 | +72.6% | COM | 22663K107 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 1,706,469 | $210M | 7.9% | $120.72 | -2.4% | SHS USD | G50871105 |
| PRTA | PROTHENA CORP PLC | 11,584,280 | $160M | 6.1% | $11.63 | +35.6% | SHS | G72800108 |
| XNCR | XENCOR INC | 6,144,767 | $141M | 5.3% | $32.11 | -28.4% | COM | 98401F105 |
| PFE | PFIZER INC | 5,000,000 | $133M | 5.0% | — | — | Call | 717081103 |
| ARVN | ARVINAS INC | 6,726,491 | $129M | 4.9% | $41.18 | -41.0% | COM | 04335A105 |
| ANAB | ANAPTYSBIO INC | 7,873,448 | $104M | 3.9% | $23.54 | +2.9% | COM | 032724106 |
| SRPT | SAREPTA THERAPEUTICS INC | 770,000 | $93.62M | 3.5% | $122.55 | 0.0% | COM | 803607100 |
| JANX | JANUX THERAPEUTICS INC | 1,469,818 | $78.69M | 3.0% | $46.95 | +12.7% | COM | 47103J105 |
| QURE | UNIQURE NV | 3,400,000 | $60.04M | 2.3% | $8.63 | 0.0% | SHS | N90064101 |
| — | SPRINGWORKS THERAPEUTICS INC | 1,560,000 | $56.36M | 2.1% | $36.13 | — | COM | 85205L107 |
| CRSP | CRISPR THERAPEUTICS AG | 1,389,276 | $54.68M | 2.1% | $71.59 | -34.0% | NAMEN AKT | H17182108 |
| IMNM | IMMUNOME INC | 3,879,415 | $41.2M | 1.6% | $8.31 | +45.3% | COM | 45257U108 |
| TECX | TECTONIC THERAPEUTIC INC | 849,143 | $39.2M | 1.5% | $15.77 | +168.1% | COM | 878972108 |
| TNGX | TANGO THERAPEUTICS INC | 10,630,736 | $32.85M | 1.2% | $7.06 | -34.2% | COM | 87583X109 |
| — | THIRD HARMONIC BIO INC | 3,182,444 | $32.75M | 1.2% | $5.25 | — | COM | 88427A107 |
| KURA | KURA ONCOLOGY INC | 3,557,269 | $30.98M | 1.2% | $18.76 | -23.3% | COM | 50127T109 |
| NGNE | NEUROGENE INC | 1,271,342 | $29.06M | 1.1% | $14.32 | +159.9% | COM | 64135M105 |
| ORIC | ORIC PHARMACEUTICALS INC | 3,418,068 | $27.58M | 1.0% | $30.24 | -69.7% | COM | 68622P109 |
| ETON | ETON PHARMACEUTICALS INC | 1,829,603 | $24.37M | 0.9% | $8.31 | +22.0% | COM | 29772L108 |
| MBX | MBX BIOSCIENCES INC | 1,259,273 | $23.21M | 0.9% | $22.77 | -6.4% | COM | 55287L101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 75,000 | $23.14M | 0.9% | $235.62 | +19.4% | COM | 558868105 |
| VYGR | VOYAGER THERAPEUTICS INC | 3,917,546 | $22.21M | 0.8% | $3.61 | — | COM | 92915B106 |
| NMRA | NEUMORA THERAPEUTICS INC. | 2,071,450 | $21.96M | 0.8% | $12.87 | -6.9% | COM | 640979100 |
| — | CARGO THERAPEUTICS INC | 1,470,000 | $21.2M | 0.8% | $16.42 | — | COM | 14179K101 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 332,522 | $18.01M | 0.7% | $51.06 | 0.0% | CLASS A ORD | 61559X104 |
| DNA | GINKGO BIOWORKS HOLDINGS INC | 1,743,344 | $17.12M | 0.6% | $8.57 | 0.0% | CL A NEW | 37611X209 |
| RNAM | AVIDITY BIOSCIENCES INC | 557,576 | $16.21M | 0.6% | $15.67 | +166.7% | COM | 05370A108 |
| — | MERSANA THERAPEUTICS INC | 11,328,000 | $16.2M | 0.6% | $1.27 | — | COM | 59045L106 |
| TCRX | TSCAN THERAPEUTICS INC | 5,000,000 | $15.2M | 0.6% | $2.68 | +69.2% | COM | 89854M101 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 27,404,070 | $14.76M | 0.6% | $1.58 | — | SPONDS ADR | 00653A107 |
| KYMR | KYMERA THERAPEUTICS INC | 350,000 | $14.08M | 0.5% | $45.17 | 0.0% | COM | 501575104 |
| DYN | DYNE THERAPEUTICS INC | 555,644 | $13.09M | 0.5% | $26.59 | +11.2% | COM | 26818M108 |
| BCYC | BICYCLE THERAPEUTICS PLC | 910,000 | $12.74M | 0.5% | $20.24 | — | SPONSORED ADS | 088786108 |
| AVIR | ATEA PHARMACEUTICALS INC | 3,341,653 | $11.19M | 0.4% | $13.03 | -74.5% | COM | 04683R106 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 862,068 | $10.92M | 0.4% | $14.27 | -2.5% | COM | 23954D109 |
| REPL | REPLIMUNE GROUP INC | 850,341 | $10.3M | 0.4% | $6.97 | +74.3% | COM | 76029N106 |
| ALGS | ALIGOS THERAPEUTICS INC | 255,573 | $10.18M | 0.4% | $12.44 | +55.4% | COM NEW | 01626L204 |
| ATRA | ATARA BIOTHERAPEUTICS INC | 532,134 | $7.083M | 0.3% | $13.75 | -23.4% | COM NEW | 046513206 |
| — | VERVE THERAPEUTICS INC | 1,250,000 | $7.05M | 0.3% | $13.94 | — | COM | 92539P101 |
| QURE | UNIQURE NV | 385,000 | $6.799M | 0.3% | $8.63 | 0.0% | Call | N90064101 |
| FATE | FATE THERAPEUTICS INC | 3,049,405 | $5.032M | 0.2% | $2.52 | 0.0% | COM | 31189P102 |
| GLPG | GALAPAGOS NV | 155,006 | $4.263M | 0.2% | $49.34 | — | SPON ADR | 36315X101 |
| — | ALLOVIR INC | 408,688 | $3.948M | 0.1% | $0.75 | — | COM | 019818103 |
| KROS | KEROS THERAPEUTICS INC | 187,500 | $2.968M | 0.1% | $59.30 | -12.4% | COM | 492327101 |
| RLAY | RELAY THERAPEUTICS INC | 641,426 | $2.643M | 0.1% | $7.47 | -27.2% | COM | 75943R102 |
| DSGN | DESIGN THERAPEUTICS INC | 426,683 | $2.633M | 0.1% | $5.65 | +2.4% | COM | 25056L103 |
| — | NUVATION BIO INC | 963,333 | $2.562M | 0.1% | $10.45 | — | *W EXP 02/10/202 | 67080N119 |
| — | GENERATION BIO CO | 2,046,867 | $2.17M | 0.1% | $4.35 | — | COM | 37148K100 |
| PRME | PRIME MEDICINE INC | 700,000 | $2.044M | 0.1% | $7.58 | -53.7% | COM | 74168J101 |
| ETON | ETON PHARMACEUTICALS INC | 151,400 | $2.017M | 0.1% | $8.31 | +22.0% | Call | 29772L108 |
| WHWK | AADI BIOSCIENCE INC | 345,253 | $1.089M | 0.0% | $1.62 | +40.1% | COM | 00032Q104 |
| UPB | UPSTREAM BIO INC | 60,000 | $986K | 0.0% | $22.33 | 0.0% | COM | 91678A107 |
| SRZNW | SURROZEN INC | 66,665 | $957K | 0.0% | $7.07 | — | *W EXP 08/01/203 | 86889P117 |
| HOOK | HOOKIPA PHARMA INC | 388,861 | $782K | 0.0% | $5.28 | -41.4% | COM NEW | 43906K209 |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | 41,453 | $418K | 0.0% | $11.59 | +3.6% | COM | 04317A107 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 21,700 | $151K | 0.0% | — | — | Call | 61225M102 |