Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2020 (← Previous) (Next →)
Filing Date: Aug 17, 2020
Total Value: $6.171B (86.0% shares, 14.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 25,182,364 | $380M | 6.2% | $15.08 * | $6.67 | +82.6% | COM | 03152W109 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 5,842,100 | $369M | 6.0% | $63.13 | $32.86 | — | COM | 37890U108 |
| — | RETROPHIN INC | 45,000,000 | $350M | 5.7% | $7.78 | $0.78 | — | NOTE 2.500% 9/1 | 761299AB2 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 11,809,494 | $324M | 5.3% | $27.45 * | $13.07 | +151.6% | COM | 462260100 |
| — | MIRATI THERAPEUTICS INC | 2,771,050 | $316M | 5.1% | $114.17 | $87.83 | — | COM | 60468T105 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 2,141,410 | $261M | 4.2% | $122.00 * | $39.11 | +182.6% | COM | 64125C109 |
| — | CYTOKINETICS INC | 10,000,000 | $238M | 3.9% | $23.83 | $23.83 | — | NOTE 4.000%11/1 | 23282WAA8 |
| BBIO | BRIDGEBIO PHARMA INC | 6,706,268 | $219M | 3.5% | $32.61 * | $27.26 | +11.7% | COM | 10806X102 |
| KOD | KODIAK SCIENCES INC | 3,513,572 | $190M | 3.1% | $54.12 * | $12.82 | +339.8% | COM | 50015M109 |
| — | VBI VACCINES INC | 55,042,465 | $171M | 2.8% | $3.10 | $1.95 | — | COM NEW | 91822J103 |
| — | COLLEGIUM PHARMACEUTICAL INC | 17,500,000 | $157M | 2.5% | $8.98 | $8.98 | — | NOTE 2.625% 2/1 | 19459JAA2 |
| — | ATHENEX INC | 11,532,467 | $156M | 2.5% | $13.52 | $14.97 | — | COM | 04685N103 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,514,358 | $148M | 2.4% | $42.00 | $22.48 | — | COM | 85205L107 |
| — | MYOKARDIA INC | 1,395,017 | $135M | 2.2% | $96.62 | $40.25 | — | COM | 62857M105 |
| — | ZOGENIX INC | 4,907,139 | $133M | 2.1% | $27.01 | $22.71 | — | COM NEW | 98978L204 |
| — | ZYMEWORKS INC | 3,580,999 | $129M | 2.1% | $36.07 | $24.49 | — | COM | 98985W102 |
| — | NEVRO CORP | 9,000,000 | $122M | 2.0% | $13.50 | $13.50 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NEVRO CORP | 899,972 | $108M | 1.7% | $119.47 | $74.32 | — | COM | 64157F103 |
| — | QUOTIENT LTD | 13,289,054 | $98.34M | 1.6% | $7.40 | $7.74 | — | COM | G73268107 |
| MGTX | MEIRAGTX HOLDINGS PLC | 6,433,277 | $80.54M | 1.3% | $12.52 * | $14.20 | -1.8% | COM | G59665102 |
| — | KADMON HLDGS INC | 15,711,334 | $80.44M | 1.3% | $5.12 | $4.45 | — | COM | 48283N106 |
| — | FREQUENCY THERAPEUTICS INC | 3,034,296 | $70.55M | 1.1% | $23.25 | $16.42 | — | COM | 35803L108 |
| — | ARENA PHARMACEUTICALS INC | 1,095,129 | $68.94M | 1.1% | $62.95 | $51.08 | — | COM NEW | 040047607 |
| ALLO | ALLOGENE THERAPEUTICS INC | 1,543,790 | $66.11M | 1.1% | $42.82 * | $26.57 | +36.1% | COM | 019770106 |
| — | PROVENTION BIO INC | 4,525,711 | $63.86M | 1.0% | $14.11 | $13.33 | — | COM | 74374N102 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 3,659,381 | $59.17M | 1.0% | $16.17 * | $25.99 | -34.4% | COM | 22663K107 |
| — | FORMA THERAPEUTICS HLDGS INC | 1,250,000 | $58.11M | 0.9% | $46.49 | $46.49 | — | SHS | 34633R104 |
| — | VAPOTHERM INC | 1,338,760 | $54.88M | 0.9% | $40.99 | $18.08 | — | COM | 922107107 |
| — | BLUEPRINT MEDICINES CORP | 688,624 | $53.71M | 0.9% | $78.00 | $65.14 | — | COM | 09627Y109 |
| — | ALBIREO PHARMA INC | 1,960,139 | $51.92M | 0.8% | $26.49 | $23.60 | — | COM | 01345P106 |
| — | NEPTUNE WELLNESS SOLUTIONS I | 18,436,906 | $51.62M | 0.8% | $2.80 | $3.51 | — | COM | 64079L105 |
| ADMA | ADMA BIOLOGICS INC | 16,584,802 | $48.59M | 0.8% | $2.93 | $4.00 | -28.1% | COM | 000899104 |
| AGIO | AGIO PHARMACEUTICALS INC | 900,000 | $48.13M | 0.8% | $53.48 * | $37.79 | +22.5% | COM | 00847X104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 2,189,010 | $45.82M | 0.7% | $20.93 * | $17.11 | +5.4% | COM | 77313F106 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 1,050,003 | $45.78M | 0.7% | $43.60 * | $38.35 | 0.0% | COM | 98943L107 |
| — | AGILE THERAPEUTICS INC | 15,919,925 | $44.26M | 0.7% | $2.78 | $1.63 | — | COM | 00847L100 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 1,104,656 | $44M | 0.7% | $39.83 * | $30.22 | +21.8% | COM | 09203E105 |
| — | MENLO THERAPEUTICS INC | 22,876,410 | $39.58M | 0.6% | $1.73 | $1.99 | — | COM | 586858102 |
| — | VERRICA PHARMACEUTICALS INC | 3,410,412 | $37.55M | 0.6% | $11.01 | $19.73 | — | COM | 92511W108 |
| — | LYRA THERAPEUTICS INC | 3,222,561 | $36.54M | 0.6% | $11.34 | $11.34 | — | COM | 55234L105 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 2,058,068 | $36.02M | 0.6% | $17.50 * | $19.57 | +0.1% | COM | 19459J104 |
| MGNX | MACROGENICS INC | 1,288,014 | $35.96M | 0.6% | $27.92 * | $17.37 | 0.0% | COM | 556099109 |
| — | FUSION PHARMACEUTICALS INC | 2,235,983 | $35.95M | 0.6% | $16.08 | $16.08 | — | COM | 36118A100 |
| — | MOLECULAR TEMPLATES INC | 2,474,133 | $34.12M | 0.6% | $13.79 | $7.26 | — | COM | 608550109 |
| — | INARI MED INC | 696,000 | $33.71M | 0.5% | $48.44 | $48.44 | — | COM | 45332Y109 |
| — | DBV TECHNOLOGIES S A | 7,317,809 | $32.13M | 0.5% | $4.39 | $8.65 | — | SPONSORED ADR | 23306J101 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,235,818 | $31.61M | 0.5% | $25.58 * | $28.83 | 0.0% | COM | 05370A108 |
| — | EIDOS THERAPEUTICS INC | 686,922 | $30.11M | 0.5% | $43.84 | $20.90 | — | COM | 28249H104 |
| GERN | GERON CORP | 13,461,538 | $29.35M | 0.5% | $2.18 * | $1.49 | 0.0% | COM | 374163103 |
| NVAX | NOVAVAX INC | 350,000 | $29.17M | 0.5% | $83.35 * | $38.25 | 0.0% | COM NEW | 670002401 |
| — | RETROPHIN INC | 3,240,112 | $28.87M | 0.5% | $8.91 | $15.94 | — | COM | 761299106 |
| PCVX | VAXCYTE INC | 850,000 | $26.87M | 0.4% | $31.61 | $32.16 | 0.0% | COM | 92243G108 |
| IMVT | IMMUNOVANT INC | 1,100,000 | $26.79M | 0.4% | $24.35 * | $21.43 | 0.0% | COM | 45258J102 |
| ATRC | ATRICURE INC | 528,776 | $23.77M | 0.4% | $44.95 * | $39.20 | +11.1% | COM | 04963C209 |
| UROV | UROVANT SCIENCES LTD | 2,366,831 | $23.29M | 0.4% | $9.84 | $9.55 | — | COM | G9381B108 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 480,000 | $23.22M | 0.4% | $48.38 * | $37.62 | -3.1% | COM | 00650F109 |
| CTMX | CYTOMX THERAPEUTICS INC | 2,577,043 | $21.47M | 0.3% | $8.33 * | $17.25 | -46.2% | COM | 23284F105 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $21.4M | 0.3% | $9.95 | $12.16 | — | COM | 206022105 |
| — | TURNING POINT THERAPEUTICS I | 329,890 | $21.31M | 0.3% | $64.59 | $39.81 | — | COM | 90041T108 |
| — | DENALI THERAPEUTICS INC | 850,000 | $20.55M | 0.3% | $24.18 | $24.18 | — | COM | 28423R105 |
| — | DICERNA PHARMACEUTICALS INC | 800,000 | $20.32M | 0.3% | $25.40 | $25.40 | — | COM | 253031108 |
| — | SOLID BIOSCIENCES INC | 6,749,803 | $19.78M | 0.3% | $2.93 | $2.93 | — | COM | 83422E105 |
| — | IVERIC BIO INC | 3,481,431 | $17.75M | 0.3% | $5.10 | $5.91 | — | COM | 46583P102 |
| — | MORPHIC HLDG INC | 650,000 | $17.58M | 0.3% | $27.05 | $19.82 | — | COM | 61775R105 |
| — | LEAP THERAPEUTICS INC | 8,476,496 | $17.47M | 0.3% | $2.06 | $1.68 | — | COM | 52187K101 |
| — | MYLAN N.V | 1,004,419 | $16.15M | 0.3% | $16.08 | $15.68 | — | SHS EURO | N59465109 |
| — | SILK RD MED INC | 385,100 | $16.13M | 0.3% | $41.89 | $36.87 | — | COM | 82710M100 |
| STOK | STOKE THERAPEUTICS INC | 671,978 | $16.01M | 0.3% | $23.83 | $26.85 | -11.6% | COM | 86150R107 |
| FULC | FULCRUM THERAPEUTICS INC | 894,118 | $15.77M | 0.3% | $17.64 * | $12.60 | +24.9% | COM | 359616109 |
| — | Y-MABS THERAPEUTICS INC | 355,366 | $15.35M | 0.2% | $43.20 | $26.06 | — | COM | 984241109 |
| ESTA | ESTABLISHMENT LABS HOLDINGS INC | 736,121 | $13.75M | 0.2% | $18.68 * | $24.75 | -31.3% | SHS | G31249108 |
| HOLX | HOLOGIC INC | 230,000 | $13.11M | 0.2% | $57.00 * | $49.07 | 0.0% | COM | 436440101 |
| ALDX | ALDEYRA THERAPEUTICS INC | 3,085,458 | $12.87M | 0.2% | $4.17 * | $6.64 | -44.9% | COM | 01438T106 |
| — | IMMUNOMEDICS INC | 362,140 | $12.83M | 0.2% | $35.44 | $35.44 | — | COM | 452907108 |
| ALEC | ALECTOR INC | 511,731 | $12.51M | 0.2% | $24.44 * | $18.92 | +45.9% | COM | 014442107 |
| TWST | TWIST BIOSCIENCE CORP | 272,756 | $12.36M | 0.2% | $45.30 * | $26.22 | +36.9% | COM | 90184D100 |
| — | BELLUS HEALTH INC NEW | 1,125,000 | $11.58M | 0.2% | $10.29 | $10.29 | — | COM NEW | 07987C204 |
| RVMD | REVOLUTION MEDICINES INC | 350,000 | $11.05M | 0.2% | $31.57 | $27.68 | +13.6% | COM | 76155X100 |
| PODD | INSULET CORP | 52,733 | $10.24M | 0.2% | $194.26 | $182.74 | +4.6% | COM | 45784P101 |
| SCPE/U | SC HEALTH CORP | 1,000,000 | $10.11M | 0.2% | $10.11 | $10.35 | — | UNIT 99/99/9999 | G78516302 |
| HCAT | HEALTH CATALYST INC | 335,782 | $9.795M | 0.2% | $29.17 * | $36.58 | -24.5% | COM | 42225T107 |
| CHRS | COHERUS BIOSCIENCES INC | 545,285 | $9.739M | 0.2% | $17.86 * | $16.93 | 0.0% | COM | 19249H103 |
| REGN | REGENERON PHARMACEUTICALS | 15,000 | $9.354M | 0.2% | $623.60 * | $410.21 | +37.6% | COM | 75886F107 |
| — | NEOLEUKIN THERAPEUTICS INC | 537,425 | $8.921M | 0.1% | $16.60 | $12.62 | — | COM | 64049K104 |
| AQST | AQUESTIVE THERAPEUTICS INC | 1,750,000 | $8.505M | 0.1% | $4.86 * | $4.60 | 0.0% | COM | 03843E104 |
| — | 1LIFE HEALTHCARE INC | 218,844 | $7.948M | 0.1% | $36.32 | $20.74 | — | COM | 68269G107 |
| — | LONGVIEW ACQUISITION CORP | 700,000 | $7.07M | 0.1% | $10.10 | $10.10 | — | UNIT 99/99/9999 | 543195200 |
| BIO | BIO RAD LABS INC | 15,489 | $6.993M | 0.1% | $451.48 * | $415.68 | +6.2% | CL A | 090572207 |
| — | AMYRIS INC | 1,844,612 | $6.449M | 0.1% | $3.50 | $3.50 | — | COM NEW | 03236M200 |
| DMTKQ | DERMTECH INC | 487,121 | $6.445M | 0.1% | $13.23 | $12.07 | — | COM | 24984K105 |
| MRNA | MODERNA INC | 100,000 | $6.421M | 0.1% | $64.21 | — | — | Put | 60770K107 |
| — | VOCERA COMMUNICATIONS INC | 290,000 | $6.148M | 0.1% | $21.20 | $23.54 | — | COM | 92857F107 |
| — | TRANSLATE BIO INC | 315,237 | $5.649M | 0.1% | $17.92 | $12.65 | — | COM | 89374L104 |
| — | MOTUS GI HLDGS INC | 4,210,542 | $5.557M | 0.1% | $1.32 | $4.01 | — | COM | 62014P108 |
| — | VERU INC | 1,650,000 | $5.511M | 0.1% | $3.34 | $1.52 | — | COM | 92536C103 |
| VRAYQ | VIEWRAY INC | 2,451,748 | $5.492M | 0.1% | $2.24 * | $9.17 | -76.7% | COM | 92672L107 |
| AXSM | AXSOME THERAPEUTICS INC | 50,000 | $4.114M | 0.1% | $82.28 * | $76.97 | 0.0% | COM | 05464T104 |
| — | BURNING ROCK BIOTECH LTD | 150,000 | $4.052M | 0.1% | $27.01 | $27.01 | — | SPONSORED ADS | 12233L107 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 400,000 | $4.004M | 0.1% | $10.01 | $10.01 | — | SPONDS ADR | 00653A107 |
| — | IMMUNOMEDICS INC | 100,000 | $3.544M | 0.1% | $35.44 | $35.44 | — | Put | 452907108 |
| — | LIFESCI ACQUISITION CORP | 300,000 | $3.3M | 0.1% | $11.00 | $9.80 | — | UNIT 03/31/2025 | 53228P208 |
| ATEC | ALPHATEC HLDGS INC | 561,574 | $2.639M | 0.0% | $4.70 * | $5.20 | -15.0% | COM NEW | 02081G201 |
| GRTX | GALERA THERAPEUTICS INC | 325,000 | $2.321M | 0.0% | $7.14 * | $12.19 | -12.9% | COM | 36338D108 |
| PHR | PHREESIA INC | 70,000 | $1.979M | 0.0% | $28.27 * | $27.64 | -5.8% | COM | 71944F106 |
| MDT | MEDTRONIC PLC | 20,000 | $1.834M | 0.0% | $91.70 * | $81.79 | 0.0% | SHS | G5960L103 |
| — | REVANCE THERAPEUTICS INC | 65,839 | $1.608M | 0.0% | $24.42 | $16.07 | — | COM | 761330109 |
| — | DYNAVAX TECHNOLOGIES CORP | 176,950 | $1.57M | 0.0% | $8.87 | $8.87 | — | COM NEW | 268158201 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $1.343M | 0.0% | $9.60 | $15.33 | — | COM | 28249U105 |
| LEGN | LEGEND BIOTECH CORP | 25,000 | $1.064M | 0.0% | $42.56 | $42.56 | — | SPONSORED ADS | 52490G102 |
| RACE | FERRARI N.V | 6,200 | $1.06M | 0.0% | $170.97 * | $40.37 | +299.3% | SHS | N3167Y103 |
| — | LIVONGO HEALTH INC | 13,620 | $1.024M | 0.0% | $75.18 | $75.18 | — | COM | 539183103 |
| — | MOMENTA PHARMACEUTICALS INC | 30,637 | $1.019M | 0.0% | $33.26 | $11.17 | — | COM | 60877T100 |
| — | TRILLIUM THERAPEUTICS INC | 114,674 | $928K | 0.0% | $8.09 | $8.09 | — | COM NEW | 89620X506 |
| — | SIERRA ONCOLOGY INC | 66,655 | $807K | 0.0% | $12.11 | $9.96 | — | COM NEW | 82640U404 |
| — | KARUNA THERAPEUTICS INC | 6,944 | $774K | 0.0% | $111.46 | $75.32 | — | COM | 48576A100 |
| AKBA | AKEBIA THERAPEUTICS INC | 52,724 | $716K | 0.0% | $13.58 * | $10.35 | 0.0% | COM | 00972D105 |
| KRMD | REPRO MED SYS INC | 74,813 | $672K | 0.0% | $8.98 * | $4.66 | +117.1% | COM | 759910102 |
| CUE | CUE BIOPHARMA INC | 26,371 | $646K | 0.0% | $24.50 | $16.16 | +49.4% | COM | 22978P106 |
| — | LUMINEX CORP DEL | 18,926 | $616K | 0.0% | $32.55 | $32.55 | — | COM | 55027E102 |
| — | CHEMOCENTRYX INC | 10,252 | $590K | 0.0% | $57.55 | $39.60 | — | COM | 16383L106 |
| TGTX | TG THERAPEUTICS INC | 29,762 | $580K | 0.0% | $19.49 * | $16.11 | 0.0% | COM | 88322Q108 |
| VIR | VIR BIOTECHNOLOGY INC | 13,024 | $534K | 0.0% | $41.00 * | $33.56 | 0.0% | COM | 92764N102 |
| APLS | APELLIS PHARMACEUTICALS INC | 11,418 | $373K | 0.0% | $32.67 | $35.50 | -9.5% | COM | 03753U106 |
| — | AVADEL PHARMACEUTICALS PLC | 8,681 | $133K | 0.0% | $15.32 | $7.60 | — | SPONSORED ADR | 05337M104 |
| — | OUTLOOK THERAPEUTICS INC | 420,875 | $108K | 0.0% | $0.26 | $0.17 | — | *W EXP 02/18/202 | 69012T115 |