Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q1 2020 (← Previous) (Next →)
Filing Date: May 18, 2020
Total Value: $3.84B (99.1% shares, 0.9% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 11,670,057 | $349M | 9.1% | $12.83 | +106.6% | COM | 462260100 |
| — | GLOBAL BLOOD THERAPEUTICS INC | 6,065,726 | $310M | 8.1% | $32.86 | — | COM | 37890U108 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 3,063,263 | $265M | 6.9% | $39.11 | +150.2% | COM | 64125C109 |
| — | MIRATI THERAPEUTICS INC | 3,319,450 | $255M | 6.6% | $87.83 | — | COM | 60468T105 |
| FOLD | AMICUS THERAPEUTICS INC | 25,182,364 | $233M | 6.1% | $6.67 | +42.5% | COM | 03152W109 |
| BBIO | BRIDGEBIO PHARMA INC | 6,706,268 | $194M | 5.1% | $27.26 | +13.7% | COM | 10806X102 |
| KOD | KODIAK SCIENCES INC | 3,663,557 | $175M | 4.6% | $12.82 | +367.9% | COM | 50015M109 |
| — | ZYMEWORKS INC | 3,560,999 | $126M | 3.3% | $24.49 | — | COM | 98985W102 |
| — | NEVRO CORP | 1,092,068 | $107M | 2.8% | $74.32 | — | COM | 64157F103 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,484,358 | $94.08M | 2.5% | $22.48 | — | COM | 85205L107 |
| — | ATHENEX INC | 11,532,467 | $89.26M | 2.3% | $14.97 | — | COM | 04685N103 |
| MGTX | MEIRAGTX HOLDINGS PLC | 6,433,277 | $86.46M | 2.3% | $14.20 | +18.9% | COM | G59665102 |
| — | ZOGENIX INC | 3,452,921 | $85.39M | 2.2% | $20.89 | — | COM | 98978L204 |
| — | KADMON HOLDINGS INC | 15,711,334 | $65.83M | 1.7% | $4.45 | — | COM | 48283N106 |
| — | MYOKARDIA INC | 1,314,209 | $61.61M | 1.6% | $36.78 | — | COM | 62857M105 |
| — | FREQUENCY THERAPEUTICS INC | 3,034,296 | $54.04M | 1.4% | $16.42 | — | COM | 35803L108 |
| — | QUOTIENT LTD | 13,289,054 | $52.49M | 1.4% | $7.74 | — | COM | G73268107 |
| ADMA | ADMA BIOLOGICS INC | 16,584,802 | $47.76M | 1.2% | $4.00 | -13.5% | COM | 000899104 |
| — | VBI VACCINES INC | 45,951,556 | $43.65M | 1.1% | $1.73 | — | COM | 91822J103 |
| — | RETROPHIN INC | 2,890,608 | $42.17M | 1.1% | $16.80 | — | COM | 761299106 |
| — | BLUEPRINT MEDICINES CORP | 688,624 | $40.27M | 1.0% | $65.14 | — | COM | 09627Y109 |
| REGN | REGENERON PHARMACEUTICALS INC | 80,000 | $39.06M | 1.0% | $410.21 | 0.0% | COM | 75886F107 |
| CRNX | CRINETICS PHARMACEUTICALS INC | 2,587,953 | $38.04M | 1.0% | $29.69 | -31.0% | COM | 22663K107 |
| — | VERRICA PHARMACEUTICALS INC | 3,410,412 | $37.27M | 1.0% | $19.73 | — | COM | 92511W108 |
| — | RETROPHIN INC | 45,000,000 | $35.02M | 0.9% | $0.78 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | EIDOS THERAPEUTICS INC | 686,922 | $33.65M | 0.9% | $20.90 | — | COM | 28249H104 |
| — | MOLECULAR TEMPLATES INC | 2,474,133 | $32.88M | 0.9% | $7.26 | — | COM | 608550109 |
| — | ALBIREO PHARMA INC | 1,960,139 | $31.93M | 0.8% | $23.60 | — | COM | 01345P106 |
| AGIO | AGIOS PHARMACEUTICALS INC | 900,000 | $31.86M | 0.8% | $37.79 | +22.3% | COM | 00847X104 |
| — | VAPOTHERM INC | 1,670,067 | $31.45M | 0.8% | $18.08 | — | COM | 922107107 |
| RCKT | ROCKET PHARMACEUTICALS INC | 2,189,010 | $30.54M | 0.8% | $17.11 | +15.7% | COM | 77313F106 |
| ALLO | ALLOGENE THERAPEUTICS INC | 1,543,790 | $30.01M | 0.8% | $26.57 | -10.3% | COM | 019770106 |
| — | AGILE THERAPEUTICS INC | 15,919,325 | $29.61M | 0.8% | $1.63 | — | COM | 00847L100 |
| — | DBV TECHNOLOGIES SA | 7,317,809 | $28.68M | 0.7% | $8.65 | — | SPONSORED ADR | 23306J101 |
| — | ARENA PHARMACEUTICALS INC | 675,129 | $28.36M | 0.7% | $43.70 | — | COM | 040047607 |
| — | PROVENTION BIO INC | 3,011,574 | $27.71M | 0.7% | $12.94 | — | COM | 74374N102 |
| BDTX | BLACK DIAMOND THERAPEUTICS INC | 1,104,656 | $27.56M | 0.7% | $30.22 | 0.0% | COM | 09203E105 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 1,551,722 | $25.34M | 0.7% | $19.56 | +5.5% | COM | 19459J104 |
| CTMX | CYTOMX THERAPEUTICS INC | 3,253,923 | $24.96M | 0.7% | $17.25 | -59.6% | COM | 23284F105 |
| TBPH | THERAVANCE BIOPHARMA INC | 1,000,000 | $23.11M | 0.6% | $25.03 | 0.0% | COM | G8807B106 |
| UROV | UROVANT SCIENCES LTD | 2,366,831 | $21.82M | 0.6% | $9.55 | — | COM | G9381B108 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $19.55M | 0.5% | $12.16 | — | COM | 206022105 |
| — | MENLO THERAPEUTICS INC | 6,637,179 | $17.46M | 0.5% | $2.63 | — | COM | 586858102 |
| RGNX | REGENXBIO INC | 508,000 | $17.14M | 0.4% | $38.79 | +7.4% | COM | 75901B107 |
| — | SOLID BIOSCIENCES INC | 6,749,803 | $16.13M | 0.4% | $4.45 | — | COM | 3422E1055 |
| — | NEPTUNE WELLNESS SOLUTIONS INC | 13,436,906 | $15.72M | 0.4% | $3.77 | — | COM | 64079L105 |
| — | TURNING POINT THERAPEUTICS INC | 349,890 | $15.44M | 0.4% | $39.81 | — | COM | 90041T108 |
| STOK | STOKE THERAPEUTICS INC | 671,978 | $15.39M | 0.4% | $26.85 | -8.0% | COM | 86150R107 |
| DNLI | DENALI THERAPEUTICS INC | 850,000 | $14.88M | 0.4% | $20.86 | 0.0% | COM | 24823R105 |
| TXG | 10X GENOMICS INC | 220,000 | $13.82M | 0.4% | $55.34 | +41.0% | CLASS A COM | 88025U109 |
| PODD | INSULET CORP | 82,733 | $13.71M | 0.4% | $182.74 | 0.0% | COM | 45784P101 |
| — | REVANCE THERAPEUTICS INC | 925,000 | $13.69M | 0.4% | $16.07 | — | COM | 761330109 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES CORP | 495,000 | $13.42M | 0.3% | $37.62 | -25.8% | COM | 00650F109 |
| ESTA | ESTABLISHMENT LABS HOLDINGS INC | 922,633 | $13.33M | 0.3% | $24.75 | -10.8% | COM | G31249108 |
| ALEC | ALECTOR INC | 511,731 | $12.35M | 0.3% | $18.92 | +34.7% | COM | 014442107 |
| — | Y-MABS THERAPEUTICS INC | 522,480 | $12.09M | 0.3% | $26.06 | — | COM | 984241109 |
| GILD | GILEAD SCIENCES INC | 1,500,000 | $11.21M | 0.3% | $54.92 | 0.0% | COM | 375558103 |
| — | LEAP THERAPEUTICS INC | 6,726,496 | $10.63M | 0.3% | $1.58 | — | COM | 52187K101 |
| SDGR | SCHRODINGER INC | 250,000 | $10.54M | 0.3% | $37.76 | 0.0% | COM | 80810D103 |
| TWST | TWIST BIOSCIENCE CORP | 322,356 | $10.38M | 0.3% | $26.22 | +2.5% | COM | 90184D100 |
| — | VOCERA COMMUNICATIONS INC | 470,000 | $10.3M | 0.3% | $23.54 | — | COM | 92857F107 |
| ATRC | ATRICURE INC | 302,227 | $10.15M | 0.3% | $35.95 | 0.0% | COM | 04963C209 |
| SCPE/U | SC HEALTH CORP | 1,000,000 | $10M | 0.3% | $10.35 | — | UNIT 99/99/9999 | G78516302 |
| — | MORPHIC HOLDING INC | 650,000 | $9.542M | 0.2% | $19.82 | — | COM | 61775R105 |
| HCAT | HEALTH CATALYST INC | 328,698 | $8.375M | 0.2% | $36.77 | -16.9% | COM | 42225T107 |
| RVMD | REVOLUTION MEDICINES INC | 350,000 | $7.816M | 0.2% | $27.68 | 0.0% | COM | 76155X100 |
| ALDX | ALDEYRA THERAPEUTICS INC | 3,085,458 | $7.621M | 0.2% | $6.64 | -32.2% | COM | 01438T106 |
| — | IMMUNOVANT INC | 400,000 | $7.356M | 0.2% | $24.87 | — | UNIT 12/18/2024 | 45258J201 |
| FULC | FULCRUM THERAPEUTICS INC | 600,000 | $7.164M | 0.2% | $11.06 | +44.6% | COM | 359616109 |
| ANAB | ANAPTYSBIO INC | 500,000 | $7.07M | 0.2% | $23.65 | -35.9% | COM | 032724106 |
| — | CERNER CORP | 105,000 | $6.745M | 0.2% | $70.16 | — | COM | 156782104 |
| — | SILK ROAD MEDICAL INC | 204,600 | $6.639M | 0.2% | $32.45 | — | COM | 82710M100 |
| — | MYLAN N.V. | 400,000 | $6.028M | 0.2% | $15.07 | — | SHS EURO | N59465109 |
| VRAYQ | VIEWRAY INC | 2,451,748 | $5.713M | 0.1% | $9.17 | -69.1% | COM | 92672L107 |
| — | NEOLEUKIN THERAPEUTICS INC | 500,000 | $5.535M | 0.1% | $12.32 | — | COM | 64049K104 |
| — | VERU INC REGISTERED SHS | 1,650,000 | $5.396M | 0.1% | $1.52 | — | COM | 92536C103 |
| — | TRANSLATE BIO INC | 435,000 | $4.994M | 0.1% | $12.65 | — | COM | 89374L104 |
| ZBH | ZIMMER BIOMET HOLDINGS INC | 50,000 | $4.914M | 0.1% | $122.61 | +1.8% | COM | 98956P102 |
| — | MEI PHARMA INC | 3,030,440 | $4.879M | 0.1% | $1.61 | — | COM NEW | 55279B202 |
| — | IVERIC BIO INC | 1,377,289 | $4.738M | 0.1% | $7.14 | — | COM | 46583P102 |
| IDYA | IDEAYA BIOSCIENCES INC | 1,141,484 | $4.702M | 0.1% | $10.88 | -34.9% | COM | 45166A102 |
| — | AQUESTIVE THERAPEUTICS INC | 1,750,000 | $3.833M | 0.1% | $6.27 | — | COM | 3843E1047 |
| — | 1LIFE HEALTHCARE INC | 185,000 | $3.31M | 0.1% | $17.89 | — | COM | 68269G107 |
| DMTKQ | DERMTECH INC | 285,856 | $3.215M | 0.1% | $11.25 | — | COM | 24984K105 |
| GRTX | GALERA THERAPEUTICS INC | 325,000 | $3.088M | 0.1% | $12.19 | +5.7% | COM | 36338D108 |
| — | ABEONA THERAPEUTICS INC | 1,500,000 | $3.06M | 0.1% | $3.27 | — | COM | 00289Y107 |
| — | LIFESCI ACQUISITION CORP | 300,000 | $2.94M | 0.1% | $9.80 | — | UNIT 3/31/2025 | 53228P208 |
| — | MOTUS GI HLDGS INC | 4,210,542 | $2.837M | 0.1% | $4.01 | — | COM | 62014P108 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 170,859 | $2.6M | 0.1% | $22.21 | -19.4% | COM | 76243J105 |
| ATEC | ALPHATEC HOLDINGS INC | 561,574 | $2.021M | 0.1% | $5.20 | +10.6% | COM | 02081G201 |
| PHR | PHREESIA INC | 70,000 | $1.424M | 0.0% | $27.64 | -0.8% | COM | 71944F106 |
| BIO | BIO-RAD LABORATORIES INC | 3,489 | $1.218M | 0.0% | $327.56 | +12.2% | COM | 090572207 |
| — | AXONICS MODULATION TECHNOLOGIES INC | 50,000 | $1.188M | 0.0% | $27.71 | — | COM | 05465P101 |
| — | THERAPEUTICSMD INC | 1,096,101 | $1.173M | 0.0% | $2.42 | — | COM | 88338N107 |
| RACE | FERRARI N.V. | 6,200 | $957K | 0.0% | $40.37 | +299.4% | COM | N3167Y103 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $951K | 0.0% | $15.33 | — | COM | 28249U105 |
| — | MOMENTA PHARMACEUTICALS INC | 30,637 | $881K | 0.0% | $11.17 | — | COM | 60877T100 |
| — | ZOGENIX INC | 300,000 | $724K | 0.0% | $20.89 | — | Put | 98978L204 |
| — | SIERRA ONCOLOGY INC | 66,654 | $664K | 0.0% | $9.96 | — | COM | 82640U404 |
| — | ACCELERON PHARMA INC | 6,813 | $583K | 0.0% | $85.57 | — | COM | 00434H108 |
| KRMD | REPRO MED SYS INC | 74,813 | $537K | 0.0% | $4.66 | +44.4% | COM | 759910102 |
| — | LUMINEX CORP | 18,926 | $500K | 0.0% | $26.42 | — | COM | 5027E1029 |
| — | KARUNA THERAPEUTICS INC | 6,944 | $497K | 0.0% | $75.32 | — | COM | 48576A100 |
| — | CHEMOCENTRYX INC | 10,252 | $406K | 0.0% | $39.60 | — | COM | 16383L106 |
| CUE | CUE BIOPHARMA INC | 26,371 | $362K | 0.0% | $16.16 | 0.0% | COM | 22978P106 |
| APLS | APELLIS PHARMACEUTICALS INC | 11,418 | $327K | 0.0% | $35.50 | 0.0% | COM | 03753U106 |
| MREO | MEREO BIOPHARMA GROUP PLC | 179,419 | $187K | 0.0% | $2.52 | — | ADS | 589492107 |
| — | ARTARA THERAPEUTICS INC | 8,543 | $184K | 0.0% | $21.54 | — | COM | 04300J107 |
| SPY | SPDR S&P 500 ETF TR | 325,000 | $159K | 0.0% | — | — | Call | 78462F103 |
| — | MIRATI THERAPEUTICS INC | 100,000 | $149K | 0.0% | $87.83 | — | Put | 60468T105 |
| — | AVADEL PHARMACEUTICALS PLC | 8,681 | $76,000 | 0.0% | $7.60 | — | ADR | 05337M104 |
| — | OUTLOOK THERAPEUTICS INC | 420,875 | $46,000 | 0.0% | $0.17 | — | W EXP 02/18/202 | 69012T115 |
| — | RESTORBIO INC | 9,306 | $10,000 | 0.0% | $1.50 | — | COM | 76133L103 |