Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q3 2020 (← Previous) (Next →)
Filing Date: Nov 16, 2020
Total Value: $6.85B (86.7% shares, 13.3% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | MIRATI THERAPEUTICS INC | 3,435,575 | $570M | 8.3% | $166.05 | $102.96 | — | COM | 60468T105 |
| — | RETROPHIN INC | 45,000,000 | $390M | 5.7% | $8.67 | $0.78 | — | NOTE 2.500% 9/1 | 761299AB2 |
| FOLD | AMICUS THERAPEUTICS INC | 25,122,048 | $355M | 5.2% | $14.12 * | $6.67 | +118.4% | COM | 03152W109 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 10,085,632 | $332M | 4.8% | $32.92 * | $13.07 | +134.6% | COM | 462260100 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 5,800,996 | $320M | 4.7% | $55.14 | $32.86 | — | COM | 37890U108 |
| BBIO | BRIDGEBIO PHARMA INC | 6,706,268 | $252M | 3.7% | $37.52 * | $27.26 | +15.4% | COM | 10806X102 |
| — | CYTOKINETICS INC | 9,770,000 | $218M | 3.2% | $22.34 | $23.83 | — | NOTE 4.000%11/1 | 23282WAA8 |
| — | ZYMEWORKS INC | 4,400,999 | $205M | 3.0% | $46.58 | $28.60 | — | COM | 98985W102 |
| — | MYOKARDIA INC | 1,395,017 | $190M | 2.8% | $136.33 | $40.25 | — | COM | 62857M105 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,481,148 | $166M | 2.4% | $47.67 | $22.48 | — | COM | 85205L107 |
| — | COLLEGIUM PHARMACEUTICAL INC | 17,500,000 | $164M | 2.4% | $9.36 | $8.98 | — | NOTE 2.625% 2/1 | 19459JAA2 |
| — | ATHENEX INC | 13,532,467 | $161M | 2.4% | $11.92 | $14.52 | — | COM | 04685N103 |
| — | VBI VACCINES INC | 55,042,465 | $157M | 2.3% | $2.86 | $1.95 | — | COM NEW | 91822J103 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,548,715 | $149M | 2.2% | $96.16 * | $39.11 | +195.8% | COM | 64125C109 |
| — | OUTSET MED INC | 2,847,822 | $142M | 2.1% | $50.00 | $50.00 | — | COM | 690145107 |
| — | NEVRO CORP | 9,000,000 | $142M | 2.1% | $15.76 | $13.50 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | NEVRO CORP | 826,164 | $115M | 1.7% | $139.30 | $74.32 | — | COM | 64157F103 |
| CRSP | CRISPR THERAPEUTICS AG | 1,341,308 | $112M | 1.6% | $83.64 * | $88.70 | 0.0% | NAMEN AKT | H17182108 |
| RLAY | RELAY THERAPEUTICS INC | 2,329,407 | $99.21M | 1.4% | $42.59 * | $38.13 | 0.0% | COM | 75943R102 |
| MGTX | MEIRAGTX HLDGS PLC | 6,433,277 | $85.18M | 1.2% | $13.24 | $14.20 | -7.3% | COM | G59665102 |
| — | QUOTIENT LTD | 16,200,818 | $83.27M | 1.2% | $5.14 | $7.28 | — | SHS | G73268107 |
| — | ALBIREO PHARMA INC | 2,360,139 | $78.76M | 1.1% | $33.37 | $25.25 | — | COM | 01345P106 |
| — | IMMUNOMEDICS INC | 912,140 | $77.56M | 1.1% | $85.03 | $65.34 | — | COM | 452907108 |
| NVAX | NOVAVAX INC | 707,715 | $76.68M | 1.1% | $108.35 * | $80.49 | +51.3% | COM NEW | 670002401 |
| CHRS | COHERUS BIOSCIENCES INC | 3,636,485 | $66.69M | 1.0% | $18.34 | $18.35 | +1.4% | COM | 19249H103 |
| — | FREQUENCY THERAPEUTICS INC | 3,256,518 | $62.56M | 0.9% | $19.21 | $16.61 | — | COM | 35803L108 |
| — | FORMA THERAPEUTICS HLDGS INC | 1,250,000 | $62.3M | 0.9% | $49.84 | $46.49 | — | SHS | 34633R104 |
| KOD | KODIAK SCIENCES INC | 1,043,021 | $61.76M | 0.9% | $59.21 * | $12.82 | +291.4% | COM | 50015M109 |
| — | BLUEPRINT MEDICINES CORP | 664,574 | $61.61M | 0.9% | $92.70 | $65.14 | — | COM | 09627Y109 |
| — | KADMON HLDGS INC | 15,711,334 | $61.59M | 0.9% | $3.92 | $4.45 | — | COM | 48283N106 |
| — | RETROPHIN INC | 3,240,112 | $59.81M | 0.9% | $18.46 | $15.94 | — | COM | 761299106 |
| — | INARI MED INC | 848,500 | $58.56M | 0.9% | $69.02 | $52.14 | — | COM | 45332Y109 |
| — | ATHIRA PHARMA INC | 3,114,805 | $57.5M | 0.8% | $18.46 | $18.46 | — | COM | 04746L104 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 3,659,381 | $57.34M | 0.8% | $15.67 * | $25.99 | -41.2% | COM | 22663K107 |
| — | PROVENTION BIO INC | 4,265,711 | $54.73M | 0.8% | $12.83 | $13.33 | — | COM | 74374N102 |
| RCKT | ROCKET PHARMACEUTICALS INC | 2,189,010 | $50.04M | 0.7% | $22.86 * | $17.11 | +44.0% | COM | 77313F106 |
| IMVT | IMMUNOVANT INC | 1,400,000 | $49.27M | 0.7% | $35.19 * | $23.28 | +29.2% | COM | 45258J102 |
| — | AGILE THERAPEUTICS INC | 15,919,925 | $48.4M | 0.7% | $3.04 | $1.63 | — | COM | 00847L100 |
| — | ARENA PHARMACEUTICALS INC | 625,129 | $46.75M | 0.7% | $74.79 | $51.08 | — | COM NEW | 040047607 |
| ALDX | ALDEYRA THERAPEUTICS INC | 6,285,458 | $46.58M | 0.7% | $7.41 * | $6.55 | -1.3% | COM | 01438T106 |
| ALLO | ALLOGENE THERAPEUTICS INC | 1,143,790 | $43.13M | 0.6% | $37.71 | $26.57 | +41.9% | COM | 019770106 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 2,058,068 | $42.85M | 0.6% | $20.82 * | $19.57 | -7.7% | COM | 19459J104 |
| PCVX | VAXCYTE INC | 850,000 | $41.97M | 0.6% | $49.38 * | $32.16 | +23.8% | COM | 92243G108 |
| — | NEPTUNE WELLNESS SOLUTIONS I | 19,436,906 | $41.01M | 0.6% | $2.11 | $3.44 | — | COM | 64079L105 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 830,000 | $40.36M | 0.6% | $48.63 * | $39.48 | +6.5% | COM | 00650F109 |
| ADMA | ADMA BIOLOGICS INC | 16,584,802 | $39.64M | 0.6% | $2.39 * | $4.00 | -31.4% | COM | 000899104 |
| — | VYNE THERAPEUTICS INC | 22,876,410 | $37.98M | 0.6% | $1.66 | $1.66 | — | COM NEW | 92941V100 |
| CMPS | COMPASS PATHWAYS PLC | 1,047,404 | $36.55M | 0.5% | $34.90 | $34.90 | — | SPONSORED ADS | 20451W101 |
| — | LYRA THERAPEUTICS INC | 3,222,561 | $36.03M | 0.5% | $11.18 | $11.34 | — | COM | 55234L105 |
| — | SILK RD MED INC | 520,100 | $34.96M | 0.5% | $67.21 | $44.75 | — | COM | 82710M100 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,235,818 | $34.79M | 0.5% | $28.15 * | $28.83 | +0.2% | COM | 05370A108 |
| — | EIDOS THERAPEUTICS INC | 686,922 | $34.71M | 0.5% | $50.53 | $20.90 | — | COM | 28249H104 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 1,050,003 | $34.33M | 0.5% | $32.69 * | $38.35 | -8.7% | COM | 98943L107 |
| MGNX | MACROGENICS INC | 1,291,181 | $32.52M | 0.5% | $25.19 * | $17.37 | +57.2% | COM | 556099109 |
| — | TURNING POINT THERAPEUTICS I | 329,890 | $28.82M | 0.4% | $87.36 | $39.81 | — | COM | 90041T108 |
| BIIB | BIOGEN INC | 100,000 | $28.37M | 0.4% | $283.68 | — | — | Call | 09062X103 |
| — | MOLECULAR TEMPLATES INC | 2,474,133 | $27.02M | 0.4% | $10.92 | $7.26 | — | COM | 608550109 |
| — | FUSION PHARMACEUTICALS INC | 2,235,983 | $26.88M | 0.4% | $12.02 | $16.08 | — | COM | 36118A100 |
| IMTX | IMMATICS N.V | 2,500,000 | $26.52M | 0.4% | $10.61 | $10.53 | 0.0% | SHS | N44445109 |
| — | VERRICA PHARMACEUTICALS INC | 3,410,412 | $26.4M | 0.4% | $7.74 | $19.73 | — | COM | 92511W108 |
| GERN | GERON CORP | 13,461,538 | $23.42M | 0.3% | $1.74 * | $1.49 | +23.7% | COM | 374163103 |
| STOK | STOKE THERAPEUTICS INC | 671,978 | $22.5M | 0.3% | $33.49 * | $26.85 | +6.3% | COM | 86150R107 |
| XBI | SPDR SER TR | 200,000 | $22.29M | 0.3% | $111.43 | — | — | Put | 78464A870 |
| UROV | UROVANT SCIENCES LTD | 2,366,831 | $22.11M | 0.3% | $9.34 | $9.55 | — | SHS | G9381B108 |
| — | THERAPEUTICS ACQUISITION COR | 1,500,000 | $21.57M | 0.3% | $14.38 | $14.38 | — | COM CL A | 88339T103 |
| PMVP | PMV PHARMACEUTICALS INC | 605,556 | $21.5M | 0.3% | $35.50 * | $36.80 | 0.0% | COM | 69353Y103 |
| WVE | WAVE LIFE SCIENCES LTD | 2,500,000 | $21.23M | 0.3% | $8.49 * | $10.96 | 0.0% | SHS | Y95308105 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $21.12M | 0.3% | $9.82 | $12.16 | — | COM | 206022105 |
| — | IVERIC BIO INC | 3,481,431 | $19.64M | 0.3% | $5.64 | $5.91 | — | COM | 46583P102 |
| — | UNUM THERAPEUTICS INC | 7,955,000 | $18.61M | 0.3% | $2.34 | $2.34 | — | COM | 903214104 |
| — | VERONA PHARMA PLC | 2,888,889 | $18.03M | 0.3% | $6.24 | $6.24 | — | SPONSORED ADS | 925050106 |
| CTMX | CYTOMX THERAPEUTICS INC | 2,577,043 | $17.14M | 0.3% | $6.65 * | $17.25 | -57.0% | COM | 23284F105 |
| — | LEAP THERAPEUTICS INC | 8,476,496 | $16.78M | 0.2% | $1.98 | $1.68 | — | COM | 52187K101 |
| — | MYLAN N.V | 1,004,419 | $14.89M | 0.2% | $14.83 | $15.68 | — | SHS EURO | N59465109 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 435,377 | $14.76M | 0.2% | $33.90 * | $36.46 | 0.0% | COM | 413197104 |
| — | DICERNA PHARMACEUTICALS INC | 800,000 | $14.39M | 0.2% | $17.99 | $25.40 | — | COM | 253031108 |
| — | SOLID BIOSCIENCES INC | 6,749,803 | $13.7M | 0.2% | $2.03 | $2.93 | — | COM | 83422E105 |
| — | AMERICAN WELL CORP | 455,000 | $13.49M | 0.2% | $29.64 | $29.64 | — | CL A | 03044L105 |
| — | MORPHIC HLDG INC | 487,000 | $13.31M | 0.2% | $27.34 | $19.82 | — | COM | 61775R105 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 678,633 | $12.57M | 0.2% | $18.53 * | $24.75 | -28.1% | COM | G31249108 |
| PPH | VANECK VECTORS ETF TR | 200,000 | $12.43M | 0.2% | $62.17 | — | — | Put | 92189F692 |
| — | DBV TECHNOLOGIES S A | 6,806,975 | $11.78M | 0.2% | $1.73 | $8.65 | — | SPONSORED ADR | 23306J101 |
| — | ACCOLADE INC | 293,138 | $11.39M | 0.2% | $38.87 | $38.87 | — | COM | 00437E102 |
| HOLX | HOLOGIC INC | 170,000 | $11.3M | 0.2% | $66.47 * | $49.07 | +29.0% | COM | 436440101 |
| HCAT | HEALTH CATALYST INC | 291,084 | $10.65M | 0.2% | $36.60 * | $36.58 | -7.2% | COM | 42225T107 |
| SCPE/U | SC HEALTH CORP | 1,000,000 | $10.6M | 0.2% | $10.60 | $10.35 | — | UNIT 99/99/9999 | G78516302 |
| TSHA | TAYSHA GENE THERAPIES INC | 470,440 | $10.54M | 0.2% | $22.40 * | $23.52 | 0.0% | COM SHS | 877619106 |
| TARA | PROTARA THERAPEUTICS INC | 608,544 | $10.24M | 0.1% | $16.83 * | $23.19 | 0.0% | COM STK | 74365U107 |
| PODD | INSULET CORP | 37,733 | $8.927M | 0.1% | $236.58 * | $182.74 | +15.3% | COM | 45784P101 |
| ATRC | ATRICURE INC | 216,449 | $8.636M | 0.1% | $39.90 * | $39.20 | +8.2% | COM | 04963C209 |
| VRAYQ | VIEWRAY INC | 2,451,748 | $8.581M | 0.1% | $3.50 * | $9.17 | -69.6% | COM | 92672L107 |
| — | AMYRIS INC | 3,333,332 | $8.568M | 0.1% | $2.57 | $3.08 | — | COM NEW | 03236M200 |
| TWST | TWIST BIOSCIENCE CORP | 112,756 | $8.566M | 0.1% | $75.97 * | $26.22 | +137.5% | COM | 90184D100 |
| AQST | AQUESTIVE THERAPEUTICS INC | 1,750,000 | $8.496M | 0.1% | $4.85 * | $4.60 | +42.0% | COM | 03843E104 |
| — | TCR2 THERAPEUTICS INC | 400,000 | $8.128M | 0.1% | $20.32 | $20.32 | — | COM | 87808K106 |
| DYN | DYNE THERAPEUTICS INC | 400,000 | $8.076M | 0.1% | $20.19 * | $21.96 | 0.0% | COM | 26818M108 |
| — | 1LIFE HEALTHCARE INC | 279,844 | $7.936M | 0.1% | $28.36 | $22.40 | — | COM | 68269G107 |
| RVMD | REVOLUTION MEDICINES INC | 224,224 | $7.803M | 0.1% | $34.80 * | $27.68 | +0.1% | COM | 76155X100 |
| — | LONGVIEW ACQUISITION CORP | 700,000 | $7.105M | 0.1% | $10.15 | $10.10 | — | UNIT 99/99/9999 | 543195200 |
| — | POSEIDA THERAPEUTICS INC | 787,745 | $6.987M | 0.1% | $8.87 | $8.87 | — | COM | 73730P108 |
| — | BCTG ACQUISITION CORP | 500,000 | $5.18M | 0.1% | $10.36 | $10.36 | — | COM | 05492W103 |
| — | HEALTH SCIENCES ACQ CORP 2 | 450,000 | $4.95M | 0.1% | $11.00 | $11.00 | — | ORD SHS | G4411D109 |
| — | VERU INC | 1,650,000 | $4.323M | 0.1% | $2.62 | $1.52 | — | COM | 92536C103 |
| — | TRANSLATE BIO INC | 315,237 | $4.29M | 0.1% | $13.61 | $12.65 | — | COM | 89374L104 |
| — | LIFESCI ACQUISITION CORP | 300,000 | $4.08M | 0.1% | $13.60 | $9.80 | — | UNIT 03/31/2025 | 53228P208 |
| — | MOTUS GI HLDGS INC | 4,210,542 | $4.027M | 0.1% | $0.96 | $4.01 | — | COM | 62014P108 |
| — | BURNING ROCK BIOTECH LTD | 150,000 | $3.762M | 0.1% | $25.08 | $27.01 | — | SPONSORED ADS | 12233L107 |
| ATEC | ALPHATEC HLDGS INC | 561,574 | $3.729M | 0.1% | $6.64 * | $5.20 | +8.5% | COM NEW | 02081G201 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 400,000 | $3.192M | 0.0% | $7.98 | $10.01 | — | SPONDS ADR | 00653A107 |
| — | DEERFIELD HEALTHCARE TECH AC | 300,000 | $3.189M | 0.0% | $10.63 | $10.63 | — | UNIT 07/16/2025 | 244413209 |
| GRTX | GALERA THERAPEUTICS INC | 325,000 | $2.938M | 0.0% | $9.04 * | $12.19 | -35.0% | COM | 36338D108 |
| REGN | REGENERON PHARMACEUTICALS | 5,000 | $2.799M | 0.0% | $559.80 * | $410.21 | +47.0% | COM | 75886F107 |
| — | TRILLIUM THERAPEUTICS INC | 114,674 | $1.63M | 0.0% | $14.21 | $8.09 | — | COM NEW | 89620X506 |
| — | LIVONGO HEALTH INC | 10,663 | $1.493M | 0.0% | $140.02 | $75.18 | — | COM | 539183103 |
| RACE | FERRARI N V | 6,200 | $1.141M | 0.0% | $184.03 | $40.37 | +360.8% | COM | N3167Y103 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $1.138M | 0.0% | $8.13 | $15.33 | — | COM | 28249U105 |
| TGTX | TG THERAPEUTICS INC | 33,893 | $907K | 0.0% | $26.76 * | $16.95 | +35.8% | COM | 88322Q108 |
| LEGN | LEGEND BIOTECH CORP | 25,000 | $772K | 0.0% | $30.88 | $42.56 | — | SPONSORED ADS | 52490G102 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 49,751 | $738K | 0.0% | $14.83 * | $11.71 | 0.0% | COM NEW | 15117B202 |
| — | SIERRA ONCOLOGY INC | 66,655 | $711K | 0.0% | $10.67 | $9.96 | — | COM NEW | 82640U404 |
| — | AKERO THERAPEUTICS INC | 21,938 | $675K | 0.0% | $30.77 | $30.77 | — | COM | 00973Y108 |
| — | COVETRUS INC | 26,075 | $636K | 0.0% | $24.39 | $24.39 | — | COM | 22304C100 |
| PSNL | PERSONALIS INC | 27,272 | $591K | 0.0% | $21.67 * | $19.87 | 0.0% | COM | 71535D106 |
| REPL | REPLIMUNE GROUP INC | 19,230 | $443K | 0.0% | $23.04 | $22.79 | 0.0% | COM | 76029N106 |
| BIO | BIO RAD LABS INC | 489 | $252K | 0.0% | $515.34 | $415.68 | +21.8% | CL A | 090572207 |
| — | OUTLOOK THERAPEUTICS INC | 420,875 | $54,000 | 0.0% | $0.13 | $0.17 | — | *W EXP 02/18/202 | 69012T115 |