Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q3 2014 (← Previous) (Next →)
Filing Date: Nov 17, 2014
Total Value: $988M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 12,339,444 | $73.42M | 7.4% | $5.95 * | $2.36 | +122.1% | COM | 03152W109 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 4,565,267 | $71.54M | 7.2% | $15.67 * | $12.74 | +17.3% | COM | 64125C109 |
| — | AFFIMED THERAPEUTICS B V | 999,989 | $63.01M | 6.4% | $63.01 | $63.01 | — | COM | N01045108 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,596,691 | $54.79M | 5.5% | $21.10 * | $34.39 | -34.4% | COM | 803607100 |
| — | ACELRX PHARMACEUTICALS INC | 6,574,060 | $36.09M | 3.7% | $5.49 | $9.69 | — | COM | 00444T100 |
| — | CELGENE CORP | 377,448 | $35.77M | 3.6% | $94.78 | $112.47 | — | COM | 151020104 |
| PTCT | PTC THERAPEUTICS INC | 671,736 | $29.56M | 3.0% | $44.01 * | $26.87 | +16.4% | COM | 69366J200 |
| — | DYAX CORP | 2,835,498 | $28.7M | 2.9% | $10.12 | $7.87 | — | COM | 26746E103 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,097,914 | $27.18M | 2.8% | $24.76 * | $24.52 | -4.6% | COM | 004225108 |
| VRTX | VERTEX PHARMACEUTICALS INC | 240,142 | $26.97M | 2.7% | $112.31 * | $73.30 | +29.9% | COM | 92532F100 |
| SRPT | Sarepta Therapeutics Inc | 1,250,000 | $26.38M | 2.7% | $21.10 * | $34.39 | -34.4% | Call | 803607100 |
| ZBH | ZIMMER HLDGS INC | 252,500 | $25.39M | 2.6% | $100.55 * | $88.71 | +1.0% | COM | 98956P102 |
| — | TARO PHARMACEUTICAL INDS LTD | 140,935 | $21.68M | 2.2% | $153.86 | $128.56 | — | SHS | M8737E108 |
| — | LION BIOTECHNOLOGIES | 2,914,549 | $20.84M | 2.1% | $7.15 | $9.44 | — | COM | 53619R102 |
| — | OPHTHOTECH CORP | 520,165 | $20.25M | 2.0% | $38.93 | $37.70 | — | COM | 683745103 |
| — | OTONOMY INC | 837,400 | $20.1M | 2.0% | $24.00 | $24.00 | — | COM | 68906L105 |
| — | RECEPTOS INC | 313,594 | $19.48M | 2.0% | $62.11 | $49.28 | — | COM | 756207106 |
| — | TESARO INC | 708,284 | $19.07M | 1.9% | $26.92 | $34.27 | — | COM | 881569107 |
| — | ARROWHEAD RESH CORP | 1,247,495 | $18.43M | 1.9% | $14.77 | $15.15 | — | COM NEW | 042797209 |
| XNCR | XENCOR INC | 1,922,707 | $17.9M | 1.8% | $9.31 * | $8.89 | +13.9% | COM | 98401F105 |
| HCA | HCA HOLDINGS INC | 230,306 | $16.24M | 1.6% | $70.52 * | $48.98 | +25.4% | COM | 40412C101 |
| — | RELYPSA INC | 762,705 | $16.09M | 1.6% | $21.09 | $23.78 | — | COM | 759531106 |
| — | ACCELERON PHARMA INC | 445,000 | $13.46M | 1.4% | $30.24 | $32.75 | — | COM | 00434H108 |
| — | RETROPHIN INC | 1,379,137 | $12.44M | 1.3% | $9.02 | $7.94 | — | COM | 761299106 |
| — | AEGERION PHARMACEUTICALS INC | 366,754 | $12.24M | 1.2% | $33.38 | $33.38 | — | COM | 00767E102 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 653,000 | $10.23M | 1.0% | $15.67 * | $12.74 | +17.3% | Put | 64125C109 |
| — | VERSARTIS INC | 487,262 | $9.253M | 0.9% | $18.99 | $26.16 | — | COM | 92529L102 |
| — | NEPTUNE TECHNOLOGIES BIORESO | 6,700,444 | $9.072M | 0.9% | $1.35 | $3.13 | — | COM | 64077P108 |
| — | ALLERGAN INC | 50,000 | $8.91M | 0.9% | $178.20 | $169.22 | — | COM | 018490102 |
| — | FLAMEL TECHNOLOGIES SA | 610,000 | $8.729M | 0.9% | $14.31 | $13.40 | — | SPONSORED ADR | 338488109 |
| SGMO | SANGAMO BIOSCIENCES INC | 800,000 | $8.628M | 0.9% | $10.79 * | $19.28 | -32.2% | COM | 800677106 |
| — | ALCOBRA LTD | 537,000 | $8.291M | 0.8% | $15.44 | — | — | Call | M2239P109 |
| INSM | INSMED INC | 600,000 | $7.83M | 0.8% | $13.05 * | $15.60 | -3.3% | COM PAR $.01 | 457669307 |
| — | EPIZYME INC | 283,890 | $7.696M | 0.8% | $27.11 | $26.46 | — | COM | 29428V104 |
| — | ALCOBRA LTD | 487,000 | $7.519M | 0.8% | $15.44 | — | — | Put | M2239P109 |
| HRTX | HERON THERAPEUTICS INC | 885,352 | $7.375M | 0.7% | $8.33 * | $12.60 | -26.1% | COM | 427746102 |
| VNDA | VANDA PHARMACEUTICALS INC | 700,000 | $7.266M | 0.7% | $10.38 | — | — | Put | 921659108 |
| PRTA | PROTHENA CORP PLC | 300,000 | $6.648M | 0.7% | $22.16 * | $30.24 | -29.9% | SHS | G72800108 |
| — | SAGE THERAPEUTICS INC | 208,676 | $6.573M | 0.7% | $31.50 | $31.50 | — | COM | 78667J108 |
| — | LANNET INC | 134,569 | $6.147M | 0.6% | $45.68 | $45.68 | — | COM | 516012101 |
| — | TRANSENTERIX INC | 1,311,941 | $5.72M | 0.6% | $4.36 | $5.04 | — | COM NEW | 89366M201 |
| — | APPLIED GENETIC TECHNOL CORP | 296,978 | $5.527M | 0.6% | $18.61 | $20.83 | — | COM | 03820J100 |
| — | AVANIR PHARMACEUTICALS INC | 460,000 | $5.483M | 0.6% | $11.92 | $11.92 | — | CL A NEW | 05348P401 |
| — | ALLIQUA INC | 1,121,951 | $5.441M | 0.6% | $4.85 | $6.42 | — | COM | 00771V108 |
| — | ZAFGEN INC | 275,000 | $5.404M | 0.5% | $19.65 | $19.65 | — | COM | 98885E103 |
| — | BIODELIVERY SCIENCES INTL IN | 306,000 | $5.23M | 0.5% | $17.09 | $11.09 | — | COM | 09060J106 |
| — | TREVENA INC | 770,000 | $4.943M | 0.5% | $6.42 | $7.86 | — | COM | 89532E109 |
| — | PHARMACYCLICS INC | 40,000 | $4.697M | 0.5% | $117.42 | $117.42 | — | COM | 716933106 |
| MGNX | MACROGENICS INC | 213,703 | $4.466M | 0.5% | $20.90 | $26.16 | -20.9% | COM | 556099109 |
| THC | TENET HEALTHCARE CORP | 67,500 | $4.009M | 0.4% | $59.39 * | $55.80 | 0.0% | COM NEW | 88033G407 |
| — | THORATEC CORP | 147,501 | $3.943M | 0.4% | $26.73 | $26.73 | — | COM NEW | 885175307 |
| — | SPECTRANETICS CORP | 138,371 | $3.677M | 0.4% | $26.57 | $22.19 | — | COM | 84760C107 |
| — | ACTAVIS PLC | 15,000 | $3.619M | 0.4% | $241.27 | $241.27 | — | SHS | G0083B108 |
| — | CHIMERIX INC | 128,000 | $3.535M | 0.4% | $27.62 | $15.45 | — | COM | 16934W106 |
| — | AASTROM BIOSCIENCES INC | 1,100,000 | $3.135M | 0.3% | $2.85 | $2.85 | — | COM PAR$ | 00253U404 |
| — | WALGREEN CO | 50,000 | $2.964M | 0.3% | $59.28 | $55.32 | — | COM | 931422109 |
| — | PFENEX INC | 400,000 | $2.944M | 0.3% | $7.36 | $7.36 | — | COM | 717071104 |
| — | SUNESIS PHARMACEUTICALS INC | 400,000 | $2.856M | 0.3% | $7.14 | — | — | Put | 867328601 |
| — | SUNESIS PHARMACEUTICALS INC | 400,000 | $2.856M | 0.3% | $7.14 | — | — | Call | 867328601 |
| — | KERYX BIOPHARMACEUTICALS | 200,000 | $2.75M | 0.3% | $13.75 | — | — | Put | 492515101 |
| ARNI | ARNO THERAPEUTICS | 2,034,721 | $2.746M | 0.3% | $1.35 * | $1.49 | 0.0% | COM | 042564203 |
| — | TOKAI PHARMACEUTICALS INC | 180,000 | $2.725M | 0.3% | $15.14 | $15.14 | — | COM | 88907J107 |
| PBYI | PUMA BIOTECHNOLOGY INC | 11,000 | $2.624M | 0.3% | $238.55 * | $205.34 | 0.0% | COM | 74587V107 |
| — | AUSPEX PHARMACEUTICALS INC | 100,000 | $2.567M | 0.3% | $25.67 | $25.67 | — | COM | 05211J102 |
| — | QUOTIENT LTD | 263,844 | $2.493M | 0.3% | $9.45 | $8.33 | — | SHS | G73268107 |
| — | CATALYST PHARM PARTNERS INC | 750,000 | $2.49M | 0.3% | $3.32 | $3.32 | — | COM | 4888U101 |
| — | LA JOLLA PHARMACEUTICAL CO | 250,000 | $2.403M | 0.2% | $9.61 | $9.61 | — | COM PAR $.0001 2 | 503459604 |
| — | MYLAN INC | 50,000 | $2.275M | 0.2% | $45.50 | $40.54 | — | COM | 628530107 |
| — | MGC DIAGNOSTICS CORP | 327,488 | $2.227M | 0.2% | $6.80 | $8.61 | — | COM | 552768103 |
| ARDX | ARDELYX INC | 153,077 | $2.175M | 0.2% | $14.21 | $14.46 | 0.0% | COM | 039697107 |
| — | ACASTI PHARMA INC | 2,573,645 | $1.982M | 0.2% | $0.77 | $1.23 | — | CL A SHS | 00430K105 |
| — | DERMA SCIENCES INC | 215,809 | $1.798M | 0.2% | $8.33 | $12.68 | — | COM PAR $.01 | 249827502 |
| — | FIVE PRIME THERAPEUTICS INC | 150,000 | $1.76M | 0.2% | $11.73 | $17.13 | — | COM | 33830X104 |
| — | UROPLASTY INC | 697,287 | $1.743M | 0.2% | $2.50 | $2.69 | — | COM NEW | 917277204 |
| PRQR | PROQR THRAPEUTICS N V | 100,000 | $1.719M | 0.2% | $17.19 * | $16.02 | 0.0% | SHS EURO | N71542109 |
| — | GENVEC INC | 820,000 | $1.706M | 0.2% | $2.08 | $2.65 | — | COM NEW | 37246C307 |
| — | ACHILLION PHARMACEUTICALS IN | 170,000 | $1.697M | 0.2% | $9.98 | $7.57 | — | COM | 00448Q201 |
| — | HEALTH INS INNOVATIONS INC | 131,025 | $1.591M | 0.2% | $12.14 | $12.14 | — | COM CL A | 42225K106 |
| — | SYNERON MEDICAL LTD | 150,000 | $1.503M | 0.2% | $10.02 | $11.88 | — | ORD SHS | M87245102 |
| — | CLOVIS ONCOLOGY INC | 30,917 | $1.402M | 0.1% | $45.35 | $53.54 | — | COM | 189464100 |
| — | DURECT CORP | 907,064 | $1.333M | 0.1% | $1.47 | $1.33 | — | COM | 266605104 |
| PARNEUR | PARNELL PHARMACEUT HLDGS LTD | 210,000 | $1.208M | 0.1% | $5.75 | $5.75 | — | SHS | Q73622104 |
| — | CHAMPIONS ONCOLOGY | 1,625,744 | $1.203M | 0.1% | $0.74 | $0.74 | — | COM | 15870P109 |
| — | MANNKIND CORP | 200,000 | $1.182M | 0.1% | $5.91 | — | — | Put | 56400P201 |
| SNN | SMITH & NEPHEW PLC | 12,963 | $1.091M | 0.1% | $84.16 | $89.27 | — | SPDN ADR NEW | 83175M205 |
| — | ANTHERA PHARMACEUTICALS INC | 478,456 | $919K | 0.1% | $1.92 | $1.92 | — | COM NEW | 03674U201 |
| — | AQUINOX PHARMACEUTICALS INC | 130,000 | $866K | 0.1% | $6.66 | $12.73 | — | COM | 03842B101 |
| — | TRANSGENOMIC INC | 183,957 | $692K | 0.1% | $3.76 | $4.58 | — | COM NEW | 89365K305 |
| — | GALMED PHARMACEUTICALS LTD | 75,000 | $645K | 0.1% | $8.60 | $11.47 | — | SHS | M47238106 |
| — | BIOTA PHARMACEUTIALS INC | 253,400 | $626K | 0.1% | $2.47 | $6.11 | — | COM | 090694100 |
| — | ONCOTHYREON INC | 325,000 | $624K | 0.1% | $1.92 | $2.10 | — | COM | 682324108 |
| — | ABIOMED INC | 25,000 | $621K | 0.1% | $24.84 | $24.84 | — | COM | 003654100 |
| — | THRESHOLD PHARMACEUTICAL INC | 160,000 | $578K | 0.1% | $3.61 | $3.61 | — | COM NEW | 885807206 |
| — | ACHAOGEN INC | 60,000 | $538K | 0.1% | $8.97 | $15.47 | — | COM | 004449104 |
| — | MEDGENICS INC | 55,073 | $286K | 0.0% | $5.19 | $3.80 | — | COM NEW | 58436Q203 |
| — | OXIGENE INC | 123,518 | $266K | 0.0% | $2.15 | $3.73 | — | COM PAR$.001 | 691828404 |
| — | NXSTAGE MEDICAL INC | 20,000 | $263K | 0.0% | $13.15 | $13.15 | — | COM | 67072V103 |
| — | PERNIX THERAPEUTICS INC | 25,000 | $192K | 0.0% | $7.68 | — | — | Call | 71426V108 |
| ICLR | ICON PLC | 2,440 | $140K | 0.0% | $57.38 * | $43.18 | +19.2% | SHS | G4705A100 |
| — | CHINA BIOLOGIC PRODS INC | 2,400 | $130K | 0.0% | $54.17 | $44.58 | — | COM | 16938C106 |
| AMN | AMN HEALTHCARE SERVICES INC | 7,855 | $123K | 0.0% | $15.66 * | $14.25 | 0.0% | COM | 001744101 |
| — | PROVIDENCE SVC CORP | 2,532 | $122K | 0.0% | $48.18 | $48.18 | — | COM | 743815102 |
| — | MAGELLAN HEALTH INC | 2,189 | $120K | 0.0% | $54.82 | $60.30 | — | COM NEW | 559079207 |
| ENTA | ENANTA PHARMACEUTICALS INC | 3,040 | $120K | 0.0% | $39.47 | $39.86 | 0.0% | COM | 29251M106 |
| — | GENTIVA HEALTH SERVICES INC | 7,052 | $118K | 0.0% | $16.73 | $15.03 | — | COM | 37247A102 |
| — | AMSURG CORP | 2,348 | $118K | 0.0% | $50.26 | $46.21 | — | COM | 03232P405 |
| — | TRIPLE-S MGMT CORP | 5,880 | $117K | 0.0% | $19.90 | $17.86 | — | CL B | 896749108 |
| CYH | COMMUNITY HEALTH SYS INC NEW | 2,123 | $116K | 0.0% | $54.64 * | $41.56 | 0.0% | COM | 203668108 |
| UHS | UNIVERSAL HLTH SVCS INC | 1,101 | $115K | 0.0% | $104.45 * | $82.36 | +23.1% | CL B | 913903100 |
| — | SYMMETRY MED INC | 11,148 | $112K | 0.0% | $10.05 | $8.88 | — | COM | 871546206 |
| CRL | CHARLES RIV LABS INTL INC | 1,860 | $111K | 0.0% | $59.68 * | $54.87 | +4.3% | COM | 159864107 |
| CNC | CENTENE CORP DEL | 1,336 | $111K | 0.0% | $83.08 * | $17.06 | +13.0% | COM | 15135B101 |
| — | SCICLONE PHARMACEUTICALS INC | 16,035 | $110K | 0.0% | $6.86 | $6.86 | — | COM | 80862K104 |
| — | HILL ROM HLDGS INC | 2,657 | $110K | 0.0% | $41.40 | $41.40 | — | COM | 431475102 |
| — | WELLPOINT INC | 901 | $108K | 0.0% | $119.87 | $119.87 | — | COM | 94973V107 |
| SEM | SELECT MED HLDGS CORP | 9,016 | $108K | 0.0% | $11.98 * | $6.98 | 0.0% | COM | 81619Q105 |
| — | AETNA INC NEW | 1,308 | $106K | 0.0% | $81.04 | $81.08 | — | COM | 00817Y108 |
| LGND | LIGAND PHARMACEUTICALS INC | 2,245 | $105K | 0.0% | $46.77 * | $40.58 | -18.2% | COM NEW | 53220K504 |
| — | GREATBATCH INC | 2,444 | $104K | 0.0% | $42.55 | $42.55 | — | COM | 39153L106 |
| MCK | MCKESSON CORP | 527 | $103K | 0.0% | $195.45 * | $163.23 | +8.3% | COM | 58155Q103 |
| — | EXACTECH INC | 4,464 | $102K | 0.0% | $22.85 | $25.31 | — | COM | 30064E109 |
| — | MERGE HEALTHCARE INC | 43,478 | $96,000 | 0.0% | $2.21 | $2.28 | — | COM | 589499102 |
| — | ALLIANCE HEALTHCARE SRVCS IN | 3,500 | $79,000 | 0.0% | $22.57 | $22.57 | — | COM PAR $0.01 | 018606301 |
| — | PDL BIOPHARMA INC | 10,183 | $76,000 | 0.0% | $7.46 | $9.72 | — | COM | 69329Y104 |
| — | CELLULAR DYNAMICS INTL INC | 164 | $1,000 | 0.0% | $6.10 | $6.10 | — | COM | 15117V109 |