Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q3 2021 (← Previous) (Next →)
Filing Date: Nov 15, 2021
Total Value: $1.689B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NTRA | Natera Inc | 3,102,960 | $346M | 20.5% | $111.44 * | $9.81 | +1068.6% | COMM | 632307104 |
| — | Karuna Therapeutics, Inc. | 1,953,077 | $239M | 14.1% | $122.33 | $26.41 | — | COMM | 48576A100 |
| ASND | Ascendis Pharma A/S | 499,824 | $79.67M | 4.7% | $159.39 | $69.98 | — | ADR | 04351P101 |
| — | Aerovate Therapeutics, Inc. | 3,758,686 | $78.86M | 4.7% | $20.98 | $22.83 | — | COMM | 008064107 |
| AZN | AstraZeneca PLC | 1,128,272 | $67.76M | 4.0% | $60.06 | $51.45 | — | ADR | 046353108 |
| — | Y-mAbs Therapeutics, Inc. | 2,194,278 | $62.63M | 3.7% | $28.54 | $26.75 | — | COMM | 984241109 |
| VERA | Vera Therapeutics, Inc. | 2,914,776 | $50.57M | 3.0% | $17.35 * | $15.54 | +15.1% | CL A | 92337R101 |
| — | Merck & Co Inc | 600,000 | $45.07M | 2.7% | $75.11 | — | — | Call | 58933Y905 |
| UTHR | United Therapeutics Corp | 222,094 | $40.99M | 2.4% | $184.58 * | $97.02 | +103.0% | COMM | 91307C102 |
| — | Bolt Biotherapeutics, Inc. | 2,754,437 | $34.84M | 2.1% | $12.65 | $32.91 | — | COMM | 097702104 |
| ALGN | Align Technology Inc | 47,000 | $31.27M | 1.9% | $665.43 * | $554.11 | +22.6% | COMM | 016255101 |
| ABBV | Abbvie Inc | 272,600 | $29.41M | 1.7% | $107.87 * | $97.22 | 0.0% | COMM | 00287Y109 |
| GRTX | Galera Therapeutics, Inc. | 3,083,712 | $24.98M | 1.5% | $8.10 * | $12.19 | -29.7% | COMM | 36338D108 |
| HRTX | Heron Therapeutics Inc | 2,301,179 | $24.6M | 1.5% | $10.69 * | $14.56 | -16.4% | COMM | 427746102 |
| — | Bristol-Myers Squibb Co | 400,000 | $23.67M | 1.4% | $59.17 | — | — | Call | 110122908 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $23.51M | 1.4% | $11.59 | $26.29 | — | COMM | 45790W108 |
| DXCM | Dexcom Inc | 37,266 | $20.38M | 1.2% | $546.85 * | $97.33 | +29.6% | COMM | 252131107 |
| — | Blueprint Medicines Corp | 181,860 | $18.7M | 1.1% | $102.81 | $102.81 | — | COMM | 09627Y109 |
| — | Regeneron Pharmaceuticals | 30,000 | $18.16M | 1.1% | $605.17 | — | — | Put | 75886F957 |
| — | Nextcure, Inc | 2,671,856 | $18.01M | 1.1% | $6.74 | $10.01 | — | COMM | 65343E108 |
| — | Akouos, Inc. | 1,515,074 | $17.59M | 1.0% | $11.61 | $22.50 | — | COMM | 00973J101 |
| — | United Therapeutics Corp | 94,500 | $17.44M | 1.0% | $184.58 | — | — | Put | 91307C952 |
| — | Horizon Therapeutics Pub L | 157,487 | $17.25M | 1.0% | $109.54 | $109.54 | — | SHS | G46188101 |
| — | Reata Pharmaceuticals Inc | 157,488 | $15.85M | 0.9% | $100.61 | $105.51 | — | COMM | 75615P103 |
| CYTK | Cytokinetics Inc | 426,632 | $15.25M | 0.9% | $35.74 * | $20.93 | +40.7% | COMM | 23282W605 |
| — | ObsEva SA | 4,749,623 | $14.77M | 0.9% | $3.11 | $13.49 | — | COMM | H5861P103 |
| ZTS | Zoetis Inc | 76,000 | $14.76M | 0.9% | $194.14 | $193.72 | 0.0% | CL A | 98978V103 |
| INSM | Insmed Inc | 535,120 | $14.74M | 0.9% | $27.54 * | $31.01 | -15.4% | COMM | 457669307 |
| SRPT | Sarepta Therapeutics, Inc. | 157,279 | $14.54M | 0.9% | $92.48 * | $75.81 | +1.6% | COMM | 803607100 |
| — | Nucana Plc | 5,599,999 | $14.45M | 0.9% | $2.58 | $9.47 | — | ADR | 67022C106 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $14.32M | 0.8% | $3.97 | $11.51 | — | COMM | 162818108 |
| KURA | Kura Oncology Inc | 755,121 | $14.14M | 0.8% | $18.73 | $21.22 | -11.2% | COMM | 50127T109 |
| — | Agenus Inc | 2,344,410 | $12.31M | 0.7% | $5.25 | $2.72 | — | COMM | 00847G705 |
| — | Zymeworks Inc | 410,619 | $11.92M | 0.7% | $29.04 | $29.04 | — | COMM | 98985W102 |
| TVTX | Travere Therapeutics Inc | 437,280 | $10.6M | 0.6% | $24.25 * | $18.37 | 0.0% | COMM | 89422G107 |
| EXEL | Exelixis Inc | 488,414 | $10.32M | 0.6% | $21.14 * | $22.75 | -18.4% | COMM | 30161Q104 |
| — | Mirati Therapeutics Inc | 56,900 | $10.07M | 0.6% | $176.91 | $171.30 | — | COMM | 60468T105 |
| BIIB | Biogen Inc | 33,220 | $9.401M | 0.6% | $282.99 * | $302.94 | +8.2% | COMM | 09062X103 |
| — | Kadmon Holdings Inc | 1,046,312 | $9.113M | 0.5% | $8.71 | $8.71 | — | COMM | 48283N106 |
| — | ChemoCentryx Inc | 517,708 | $8.853M | 0.5% | $17.10 | $26.63 | — | COMM | 16383L106 |
| — | ChemoCentryx Inc | 505,800 | $8.649M | 0.5% | $17.10 | — | — | Put | 16383L956 |
| PTCT | PTC Therapeutics Inc | 230,019 | $8.559M | 0.5% | $37.21 * | $47.53 | -13.6% | COMM | 69366J200 |
| — | Intra-Cellular Therapies Inc | 227,419 | $8.478M | 0.5% | $37.28 | $27.53 | — | COMM | 46116X101 |
| ALXO | ALX Oncology Holdings Inc | 107,220 | $7.919M | 0.5% | $73.86 * | $66.65 | 0.0% | COMM | 00166B105 |
| SNDX | Syndax Pharmaceuticals Inc | 413,841 | $7.909M | 0.5% | $19.11 * | $16.66 | 0.0% | COMM | 87164F105 |
| CLDX | Celldex Therapeutics, Inc. | 137,032 | $7.398M | 0.4% | $53.99 * | $27.78 | +68.9% | COMM | 15117B202 |
| — | Acceleron Pharma Inc | 39,589 | $6.813M | 0.4% | $172.09 | $121.00 | — | COMM | 00434H108 |
| IMTX | Immatics N.V | 478,216 | $6.217M | 0.4% | $13.00 * | $11.02 | +15.4% | COMM | N44445109 |
| — | Nucana Plc | 2,400,000 | $6.192M | 0.4% | $2.58 | $4.99 | — | Ordinary Shares | GB00BYWYV |
| — | CTI BioPharma Corp | 2,074,714 | $6.12M | 0.4% | $2.95 | $2.91 | — | COMM | 12648L601 |
| — | Iveric Bio Inc | 357,400 | $5.804M | 0.3% | $16.24 | $16.24 | — | COMM | 46583P102 |
| — | Amarin Corp | 1,069,968 | $5.457M | 0.3% | $5.10 | $7.81 | — | ADR | 023111206 |
| RGNX | Regenxbio Inc | 127,593 | $5.349M | 0.3% | $41.92 * | $36.38 | -1.1% | COMM | 75901B107 |
| — | Protagonist Therapeutics Inc | 300,000 | $5.316M | 0.3% | $17.72 | — | — | Call | 74366E902 |
| PTGX | Protagonist Therapeutics Inc | 297,709 | $5.275M | 0.3% | $17.72 * | $25.31 | +68.5% | COMM | 74366E102 |
| GH | Guardant Health Inc | 40,000 | $5M | 0.3% | $125.00 * | $118.81 | 0.0% | COMM | 40131M109 |
| — | Jounce Therapeutics Inc | 637,347 | $4.735M | 0.3% | $7.43 | $6.97 | — | COMM | 481116101 |
| — | Sierra Oncology, Inc. | 206,564 | $4.528M | 0.3% | $21.92 | $21.89 | — | COMM | 82640U404 |
| — | Cyteir Therapeutics, Inc. | 246,321 | $4.323M | 0.3% | $17.55 | $21.40 | — | COMM | 23284P103 |
| — | Iveric Bio Inc | 255,300 | $4.146M | 0.2% | $16.24 | — | — | Put | 46583P952 |
| — | Novocure Ltd | 30,000 | $3.485M | 0.2% | $116.17 | — | — | Call | G6674U908 |
| — | Intercept Pharmaceuticals In | 190,000 | $2.822M | 0.2% | $14.85 | — | — | Call | 45845P908 |
| QURE | Uniqure NV | 78,742 | $2.521M | 0.1% | $32.02 * | $35.84 | -14.9% | COMM | N90064101 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $2.125M | 0.1% | $14.90 * | $8.36 | +49.1% | COMM | 70465T107 |
| — | Aligos Therapeutics Inc | 124,342 | $1.929M | 0.1% | $15.51 | $27.65 | — | COMM | 01626L105 |
| — | Marinus Pharmaceuticals Inc | 166,711 | $1.897M | 0.1% | $11.38 | $13.05 | — | COMM | 56854Q200 |
| — | Synlogic Inc. | 574,972 | $1.754M | 0.1% | $3.05 | $9.38 | — | COMM | 87166L100 |
| FULC | Fulcrum Therapeutics Inc | 51,006 | $1.439M | 0.1% | $28.21 * | $18.95 | 0.0% | COMM | 359616109 |
| — | Fusion Pharmaceuticals Inc | 78,066 | $618K | 0.0% | $7.92 | $7.92 | — | COMM | 36118A100 |
| PODD | Insulet Corp | 1,066 | $303K | 0.0% | $284.24 | $270.80 | +5.3% | COMM | 45784P101 |